{"text_format":"3","workbook":"xls","n_sheets":2,"sheets":["Canonical Pathway","Detail"],"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"Canonical Pathway","index":0,"n_rows":384,"n_cols":6,"rows_kept":384,"flags":["formulas_cached_only"]}
["Ingenuity Canonical Pathways"," -log(p-value)","Ratio","z-score","Molecules","Counts of AntibodyList"]
["HER-2 Signaling in Breast Cancer",4.8,0.148,"NaN","ITGB1,TSC1,GRB2,FGFR1,CDK6,FGFR2,ITGB8,PIK3R3,CCNE1,PRKCI,CDC42,CDKN1A,AKT3",7]
["Germ Cell-Sertoli Cell Junction Signaling",4.78,0.11,"NaN","ITGB1,TUBB3,TGFBR1,MAPK1,GRB2,FGFR1,WASL,TUBB2A,MAPK9,MLLT4,FGFR2,LIMK2,PIK3R3,CDH1,CDH2,CDC42,RHOU,MTMR2,NECTIN2",10]
["Glioblastoma Multiforme Signaling",4.74,0.113,-0.258,"TSC1,FZD10,MAPK1,GRB2,FGFR1,CDK6,FGFR2,ITPR1,FZD1,PTEN,PIK3R3,CCNE1,CDC42,CDKN1A,IGF1R,RHOU,AKT3,FZD5",10]
["Melanoma Signaling",4.62,0.182,"NaN","PIK3R3,CDH1,MAPK1,GRB2,MITF,FGFR1,CDKN1A,AKT3,FGFR2,PTEN",7]
["PTEN Signaling",4.59,0.126,-1.069,"ITGB1,TGFBR1,MAPK1,GRB2,FGFR1,FGFR2,CNKSR3,PTEN,PIK3R3,IKBKG,CDC42,CDKN1A,RPS6KB2,IGF1R,AKT3",9]
["IGF-1 Signaling",4.56,0.132,0.577,"PIK3R3,NEDD4,PRKCI,MAPK1,GRB2,FGFR1,IGF1R,RPS6KB2,PRKAG2,AKT3,FGFR2,IGFBP1,CYR61,GRB10",5]
["p53 Signaling",4.33,0.126,-1.508,"GADD45B,GRB2,MED1,PLAGL1,FGFR1,FGFR2,BIRC5,PTEN,CHEK1,PIK3R3,PCNA,CDKN1A,AKT3,CHEK2",8]
["Type II Diabetes Mellitus Signaling",4.26,0.118,0.535,"MAPK1,GRB2,FGFR1,MAPK9,FGFR2,CEBPB,PIK3R3,TRADD,IKBKG,PRKCI,PRKAG2,PRKAA2,AKT3,ADIPOR2,NSMAF",7]
["HGF Signaling",4.16,0.122,0.832,"ITGB1,MAPK1,GRB2,FGFR1,MAPK9,FGFR2,ATF2,MET,PIK3R3,PRKCI,CDC42,CDKN1A,AKT3,PTGS2",9]
["Gα12/13 Signaling",4.14,0.115,0.258,"MAPK1,GRB2,FGFR1,MEF2A,MAPK9,FGFR2,MYL6B,ROCK2,PIK3R3,CDH2,CDH1,IKBKG,CDC42,MEF2D,AKT3",8]
["ILK Signaling",4.03,0.0969,0.728,"ITGB1,FBLIM1,MAPK1,GRB2,FGFR1,FERMT2,MAPK9,FGFR2,MYL6B,ITGB8,ATF2,PTEN,PIK3R3,CDH1,CDC42,RHOU,AKT3,RSU1,PTGS2",9]
["Molecular Mechanisms of Cancer",3.99,0.0775,"NaN","RAP2B,FZD10,TGFBR1,MAPK1,PSENEN,SMAD5,FZD1,CHEK1,HHAT,RHOU,AKT3,CHEK2,ITGB1,GRB2,FGFR1,RALB,CDK6,MAPK9,FGFR2,PIK3R3,CDH1,CCNE1,PRKCI,CDC42,CDKN1A,PRKAG2,APH1B,FZD5,BMP6",15]
["Role of Tissue Factor in Cancer",3.88,0.115,"NaN","ITGB1,CXCL8,MAPK1,GRB2,FGFR1,PLAUR,FGFR2,LIMK2,PTEN,PIK3R3,ARRB1,CDC42,AKT3,CYR61",7]
["AMPK Signaling",3.75,0.0952,1,"PBRM1,TSC1,MAPK1,SLC2A1,GRB2,FGFR1,FGFR2,ATF2,PPM1D,PIK3R3,CDKN1A,PRKAA2,PRKAG2,AKT3,CPT1C,EEF2K,HNF4A,HMGCR",7]
["Small Cell Lung Cancer Signaling",3.67,0.131,"NaN","PIK3R3,IKBKG,CCNE1,GRB2,FGFR1,CDK6,AKT3,FGFR2,PTGS2,SKP2,PTEN",8]
["IL-17 Signaling",3.63,0.129,"NaN","PIK3R3,CXCL8,MAPK1,GRB2,FGFR1,AKT3,MAPK9,FGFR2,CEBPB,PTGS2,ATF2",8]
["Signaling by Rho Family GTPases",3.58,0.085,2.065,"GNG4,ITGB1,SEPT8,NEDD4,MAPK1,GRB2,FGFR1,WASL,MAPK9,FGFR2,MYL6B,LIMK2,ROCK2,PIK3R3,CDH1,CDH2,PRKCI,CDC42,RHOU,SEPT6,SEPT2",8]
["LPS-stimulated MAPK Signaling",3.58,0.128,0.302,"PIK3R3,IKBKG,PRKCI,ATF1,MAPK1,GRB2,CDC42,FGFR1,MAPK9,FGFR2,ATF2",5]
["Epithelial Adherens Junction Signaling",3.58,0.103,"NaN","TUBB3,TGFBR1,FGFR1,WASL,TUBB2A,MLLT4,MYL6B,PTEN,MET,CDH2,CDH1,CDC42,SSX2IP,AKT3,NECTIN2",9]
["Glucocorticoid Receptor Signaling",3.49,0.0801,"NaN","PBRM1,CXCL8,TGFBR1,MAPK1,GRB2,MED1,FGFR1,PBX1,FGFR2,MAPK9,CEBPB,HSPA5,PIK3R3,IKBKG,TAF1,CDKN1A,PRKAA2,PRKAG2,AKT3,HSP90AA1,PTGS2,SERPINE1,CREBZF",13]
["Pancreatic Adenocarcinoma Signaling",3.47,0.11,0.905,"PIK3R3,CCNE1,TGFBR1,MAPK1,CDC42,GRB2,FGFR1,CDKN1A,AKT3,FGFR2,MAPK9,PTGS2,BIRC5",11]
["Aldosterone Signaling in Epithelial Cells",3.46,0.0964,0.632,"NEDD4,MAPK1,GRB2,SLC12A2,FGFR1,DNAJC6,FGFR2,ITPR1,HSPA5,PIK3R3,PRKCI,ASIC1,DNAJC18,HSP90AA1,DNAJB6,DNAJB1",5]
["Mouse Embryonic Stem Cell Pluripotency",3.35,0.113,0,"SOX2,PIK3R3,LIFR,FZD10,MAPK1,GRB2,FGFR1,AKT3,FGFR2,FZD5,FZD1,SMAD5",4]
["Pyridoxal 5'-phosphate Salvage Pathway",3.34,0.141,"NaN","PDXK,PRKX,MAPK1,PRPF4B,PRKAA2,CDK6,MAPK9,LIMK2,HIPK1",4]
["Role of NANOG in Mammalian Embryonic Stem Cell Pluripotency",3.33,0.107,1.633,"PIK3R3,SOX2,LIFR,FZD10,MAPK1,GRB2,FGFR1,AKT3,FGFR2,FZD5,SMAD5,FZD1,BMP6",5]
["Huntington's Disease Signaling",3.3,0.083,"NaN","GNG4,MAPK1,GRB2,GLS,FGFR1,MAPK9,FGFR2,ITPR1,HSPA5,SNAP25,ATF2,HDAC6,TGM2,PIK3R3,PRKCI,CASP2,CASP1,IGF1R,AKT3,DNAJB1",10]
["Regulation of the Epithelial-Mesenchymal Transition Pathway",3.29,0.0899,"NaN","FZD10,LOX,TGFBR1,PSENEN,MAPK1,GRB2,FGFR1,FGFR2,FZD1,MET,PIK3R3,CDH1,CDH2,AKT3,APH1B,FZD5,HMGA2",9]
["PI3K/AKT Signaling",3.26,0.105,0.577,"ITGB1,PIK3R3,TSC1,IKBKG,MAPK1,GRB2,GDF15,CDKN1A,RPS6KB2,HSP90AA1,AKT3,PTGS2,PTEN",7]
["Prostate Cancer Signaling",3.24,0.117,"NaN","PIK3R3,CCNE1,MAPK1,GRB2,FGFR1,CDKN1A,HSP90AA1,AKT3,FGFR2,PTEN,ATF2",8]
["Insulin Receptor Signaling",3.23,0.0993,0.535,"TSC1,MAPK1,GRB2,FGFR1,FGFR2,PTEN,GRB10,PIK3R3,PRKCI,PDE3B,RPS6KB2,PRKAG2,ASIC1,AKT3",5]
["Role of NFAT in Cardiac Hypertrophy",3.21,0.0885,0.5,"GNG4,TGFBR1,MAPK1,GRB2,FGFR1,MEF2A,MAPK9,FGFR2,ITPR1,HDAC6,PIK3R3,PRKCI,MEF2D,IGF1R,PRKAG2,AKT3,RCAN3",8]
["Hereditary Breast Cancer Signaling",3.2,0.0986,"NaN","PBRM1,GADD45B,GRB2,FGFR1,CDK6,FGFR2,RFC1,PTEN,CHEK1,PIK3R3,HDAC6,CDKN1A,AKT3,CHEK2",7]
["Role of IL-17A in Arthritis",3.19,0.134,"NaN","PIK3R3,CXCL8,MAPK1,GRB2,FGFR1,MAPK9,FGFR2,PTGS2,ATF2",6]
["Macropinocytosis Signaling",3.18,0.123,-0.378,"ITGB1,MET,PIK3R3,RAB5A,PRKCI,GRB2,CDC42,FGFR1,FGFR2,ITGB8",4]
["Ovarian Cancer Signaling",3.13,0.0972,"NaN","FZD10,MAPK1,GRB2,FGFR1,FGFR2,FZD1,PTEN,PIK3R3,ARRB1,PRKAG2,RPS6KB2,AKT3,FZD5,PTGS2",6]
["Inflammasome pathway",3.12,0.238,-1,"CXCL8,MYD88,CASP1,NEK7,PANX1",3]
["Nitric Oxide Signaling in the Cardiovascular System",3.1,0.106,1.155,"PIK3R3,PRKCI,MAPK1,GRB2,PDE3B,FGFR1,CAV1,PRKAG2,HSP90AA1,AKT3,FGFR2,ITPR1",6]
["Cholecystokinin/Gastrin-mediated Signaling",2.98,0.109,"NaN","ROCK2,PRKCI,MAPK1,GRB2,MEF2D,MEF2A,RHOU,MAPK9,PTGS2,ITPR1,ATF2",3]
["PAK Signaling",2.98,0.109,0.905,"ITGB1,PIK3R3,MAPK1,GRB2,CDC42,FGFR1,WASL,MAPK9,FGFR2,LIMK2,MYL6B",5]
["NGF Signaling",2.97,0.103,0.905,"ROCK2,PIK3R3,IKBKG,MAPK1,GRB2,CDC42,FGFR1,RPS6KB2,AKT3,MAPK9,FGFR2,ATF2",6]
["Adipogenesis pathway",2.94,0.097,"NaN","SAP18,FZD10,SAP30L,FGFR1,FGFR2,SENP2,SMAD5,FZD1,CEBPB,HDAC6,LPL,FZD5,KLF3",2]
["Breast Cancer Regulation by Stathmin1",2.94,0.0837,"NaN","GNG4,TUBB3,MAPK1,GRB2,FGFR1,TUBB2A,FGFR2,LIMK2,ITPR1,ROCK2,PIK3R3,CCNE1,PRKCI,CDC42,CDKN1A,PRKAG2,UHMK1",8]
["Inhibition of Angiogenesis by TSP1",2.91,0.176,"NaN","TGFBR1,SDC1,MAPK1,SDC2,AKT3,MAPK9",5]
["Neuregulin Signaling",2.9,0.114,-0.707,"ITGB1,PIK3R3,PRKCI,MAPK1,GRB2,DCN,RPS6KB2,HSP90AA1,AKT3,PTEN",5]
["Glycine Biosynthesis I",2.89,1,"NaN","SHMT1,SHMT2",0]
["Chronic Myeloid Leukemia Signaling",2.87,0.106,"NaN","HDAC6,PIK3R3,IKBKG,TGFBR1,MAPK1,GRB2,FGFR1,CDKN1A,CDK6,AKT3,FGFR2",7]
["Colorectal Cancer Metastasis Signaling",2.78,0.0769,-0.471,"GNG4,FZD10,TGFBR1,MAPK1,GRB2,FGFR1,MAPK9,FGFR2,FZD1,BIRC5,PIK3R3,APPL1,CDH1,ARRB1,RHOU,PRKAG2,AKT3,FZD5,PTGS2",10]
["Estrogen-Dependent Breast Cancer Signaling",2.75,0.117,1.414,"PIK3R3,MAPK1,GRB2,FGFR1,IGF1R,AKT3,FGFR2,AKR1C4,ATF2",5]
["IL-17A Signaling in Airway Cells",2.75,0.117,1.667,"PIK3R3,IKBKG,MAPK1,GRB2,FGFR1,AKT3,MAPK9,FGFR2,PTEN",6]
["PCP pathway",2.73,0.127,0,"ROCK2,FZD10,SDC1,SDC2,MAPK9,FZD5,FZD1,ATF2",2]
["CD40 Signaling",2.71,0.115,0.707,"PIK3R3,IKBKG,ATF1,MAPK1,GRB2,FGFR1,MAPK9,FGFR2,PTGS2",5]
["Endometrial Cancer Signaling",2.69,0.125,"NaN","PIK3R3,CDH1,MAPK1,GRB2,FGFR1,AKT3,FGFR2,PTEN",6]
["Sertoli Cell-Sertoli Cell Junction Signaling",2.69,0.0843,"NaN","ITGB1,TUBB3,MAPK1,TUBB2A,MAPK9,MLLT4,ATF2,PTEN,CDH1,CDC42,CGN,PRKAG2,AKT3,MTMR2,NECTIN2",8]
["Glioma Signaling",2.68,0.1,0.905,"PIK3R3,PRKCI,MAPK1,GRB2,FGFR1,CDKN1A,IGF1R,CDK6,AKT3,FGFR2,PTEN",8]
["Antiproliferative Role of TOB in T Cell Signaling",2.67,0.192,"NaN","CCNE1,TGFBR1,MAPK1,TOB1,SKP2",4]
["IL-8 Signaling",2.66,0.0812,0.535,"GNG4,CXCL8,MAPK1,GRB2,FGFR1,MAPK9,FGFR2,LIMK2,ROCK2,PIK3R3,CDH1,IKBKG,PRKCI,RHOU,AKT3,PTGS2",9]
["Renal Cell Carcinoma Signaling",2.59,0.111,0.707,"MET,PIK3R3,SLC2A1,MAPK1,GRB2,CDC42,FGFR1,AKT3,FGFR2",6]
["Integrin Signaling",2.59,0.0776,1,"RAP2B,ITGB1,MAPK1,ASAP1,GRB2,FGFR1,WASL,RALB,FGFR2,ITGB8,PTEN,PIK3R3,CDC42,RHOU,CAV1,AKT3,NEDD9",8]
["CXCR4 Signaling",2.57,0.0848,0.832,"ROCK2,PIK3R3,GNG4,PRKCI,MAPK1,GRB2,CXCR4,FGFR1,RHOU,AKT3,MAPK9,FGFR2,MYL6B,ITPR1",6]
["Semaphorin Signaling in Neurons",2.55,0.132,"NaN","ROCK2,ITGB1,MET,CRMP1,MAPK1,RHOU,LIMK2",2]
["Superpathway of Cholesterol Biosynthesis",2.53,0.179,"NaN","SQLE,PMVK,MSMO1,HMGCR,GGPS1",0]
["FAK Signaling",2.51,0.101,"NaN","ITGB1,PIK3R3,MAPK1,ASAP1,GRB2,HMMR,FGFR1,AKT3,FGFR2,PTEN",5]
["Folate Transformations I",2.48,0.333,"NaN","SHMT1,MTR,SHMT2",0]
["Rac Signaling",2.47,0.094,0.632,"ITGB1,PIK3R3,MCF2L,ABI2,PRKCI,MAPK1,GRB2,CDC42,FGFR1,FGFR2,LIMK2",4]
["Role of CHK Proteins in Cell Cycle Checkpoint Control",2.46,0.127,0,"PCNA,CDKN1A,ATMIN,RFC1,CHEK2,CHEK1,RAD1",3]
["Axonal Guidance Signaling",2.44,0.0625,"NaN","FZD10,GLI2,MAPK1,WASL,LIMK2,MYL6B,FZD1,ROCK2,SDC2,AKT3,GNG4,ITGB1,TUBB3,CXCR4,GRB2,SEMA5A,FGFR1,TUBB2A,FGFR2,EFNA1,MET,PIK3R3,PRKCI,ADAM12,CDC42,PRKAG2,FZD5,BMP6",10]
["Glioma Invasiveness Signaling",2.44,0.114,0,"PIK3R3,MAPK1,GRB2,HMMR,FGFR1,RHOU,PLAUR,FGFR2",3]
["Virus Entry via Endocytic Pathways",2.42,0.098,"NaN","ITGB1,PIK3R3,CD55,PRKCI,GRB2,CDC42,FGFR1,CAV1,FGFR2,ITGB8",4]
["NF-κB Activation by Viruses",2.42,0.105,0.333,"ITGB1,PIK3R3,IKBKG,PRKCI,MAPK1,GRB2,FGFR1,AKT3,FGFR2",4]
["TGF-β Signaling",2.38,0.103,0.333,"TGFBR1,MAPK1,GRB2,CDC42,MAPK9,SMURF2,SMAD5,SERPINE1,HNF4A",4]
["eNOS Signaling",2.38,0.0839,0.333,"GRB2,FGFR1,FGFR2,ITPR1,HSPA5,PIK3R3,AQP3,PRKCI,PRKAG2,PRKAA2,CAV1,AKT3,HSP90AA1",7]
["GADD45 Signaling",2.37,0.211,"NaN","PCNA,CCNE1,GADD45B,CDKN1A",3]
["ErbB4 Signaling",2.36,0.111,0,"PIK3R3,PRKCI,MAPK1,PSENEN,GRB2,FGFR1,FGFR2,APH1B",4]
["NRF2-mediated Oxidative Stress Response",2.35,0.0777,-0.816,"MAPK1,GRB2,PRDX1,FGFR1,DNAJC6,MAPK9,GCLC,FGFR2,PIK3R3,GSTT2/GSTT2B,FTL,PRKCI,DNAJC18,DNAJB6,DNAJB1",4]
["FGF Signaling",2.29,0.1,1.667,"MET,PIK3R3,MAPK1,GRB2,FGFR1,AKT3,FGFR2,ITPR1,ATF2",5]
["ATM Signaling",2.28,0.119,1.633,"GADD45B,CDKN1A,MAPK9,CHEK2,CHEK1,SMC1A,ATF2",3]
["Ephrin A Signaling",2.24,0.117,"NaN","ROCK2,PIK3R3,GRB2,CDC42,FGFR1,FGFR2,EFNA1",3]
["Human Embryonic Stem Cell Pluripotency",2.24,0.0839,"NaN","SOX2,PIK3R3,FZD10,TGFBR1,GRB2,FGFR1,AKT3,FGFR2,FZD5,FZD1,SMAD5,BMP6",5]
["mTOR Signaling",2.23,0.0754,-1.508,"TSC1,MAPK1,GRB2,FGFR1,EIF3J,FGFR2,EIF3M,PIK3R3,PRKCI,RHOU,PRKAG2,PRKAA2,RPS6KB2,AKT3,RPS27A",6]
["Reelin Signaling in Neurons",2.22,0.0978,"NaN","ITGB1,PIK3R3,NDEL1,GRB2,FGFR1,MAPK8IP2,MAPK9,FGFR2,PAFAH1B3",3]
["Factors Promoting Cardiogenesis in Vertebrates",2.22,0.0978,"NaN","FZD10,CCNE1,PRKCI,TGFBR1,FZD5,FZD1,SMAD5,BMP6,ATF2",3]
["GDNF Family Ligand-Receptor Interactions",2.22,0.105,0.378,"PIK3R3,MAPK1,GRB2,CDC42,FGFR1,MAPK9,FGFR2,ITPR1",5]
["Salvage Pathways of Pyrimidine Ribonucleotides",2.19,0.0968,"NaN","PRKX,MAPK1,PRPF4B,PRKAA2,CDK6,MAPK9,CMPK1,LIMK2,HIPK1",4]
["Non-Small Cell Lung Cancer Signaling",2.19,0.104,1.134,"PIK3R3,MAPK1,GRB2,FGFR1,CDK6,AKT3,FGFR2,ITPR1",5]
["Melanocyte Development and Pigmentation Signaling",2.13,0.0947,1,"PIK3R3,MAPK1,GRB2,MITF,FGFR1,RPS6KB2,PRKAG2,FGFR2,ATF2",3]
["CNTF Signaling",2.13,0.111,0.378,"PIK3R3,LIFR,MAPK1,GRB2,FGFR1,RPS6KB2,FGFR2",3]
["14-3-3-mediated Signaling",2.12,0.0846,"NaN","PIK3R3,TSC1,TUBB3,PRKCI,MAPK1,GRB2,FGFR1,TUBB2A,AKT3,MAPK9,FGFR2",6]
["Tight Junction Signaling",2.11,0.0778,"NaN","TGFBR1,MLLT4,MYL6B,CNKSR3,SNAP25,PTEN,PRKCI,CDC42,CGN,PRKAG2,AKT3,PATJ,NECTIN2",5]
["Growth Hormone Signaling",2.06,0.0988,-0.378,"PIK3R3,PRKCI,MAPK1,GRB2,FGFR1,IGF1R,RPS6KB2,FGFR2",4]
["HMGB1 Signaling",2.05,0.0827,0,"PIK3R3,CXCL8,MAPK1,GRB2,CDC42,FGFR1,RHOU,AKT3,MAPK9,FGFR2,SERPINE1",7]
["UVB-Induced MAPK Signaling",2.02,0.106,0.378,"PIK3R3,PRKCI,MAPK1,GRB2,FGFR1,MAPK9,FGFR2",4]
["JAK/Stat Signaling",1.99,0.0964,0.707,"PIK3R3,MAPK1,GRB2,FGFR1,CDKN1A,AKT3,FGFR2,CEBPB",6]
["Lymphotoxin β Receptor Signaling",1.99,0.104,1.134,"PIK3R3,IKBKG,MAPK1,GRB2,FGFR1,AKT3,FGFR2",4]
["Ephrin Receptor Signaling",1.97,0.0747,0.905,"ROCK2,GNG4,ITGB1,MAPK1,CDC42,SDC2,CXCR4,GRB2,WASL,AKT3,LIMK2,EFNA1,ATF2",5]
["Docosahexaenoic Acid (DHA) Signaling",1.97,0.115,"NaN","PIK3R3,GRB2,FGFR1,BIK,AKT3,FGFR2",3]
["RANK Signaling in Osteoclasts",1.97,0.0891,1.667,"PIK3R3,IKBKG,MAPK1,GRB2,MITF,FGFR1,AKT3,MAPK9,FGFR2",5]
["PEDF Signaling",1.96,0.0952,0.707,"ROCK2,PIK3R3,IKBKG,MAPK1,GRB2,FGFR1,AKT3,FGFR2",4]
["EGF Signaling",1.95,0.103,1.134,"PIK3R3,MAPK1,GRB2,FGFR1,AKT3,FGFR2,ITPR1",4]
["Cardiac Hypertrophy Signaling",1.94,0.0681,1.291,"GNG4,TGFBR1,MAPK1,GRB2,FGFR1,MEF2A,MAPK9,FGFR2,MYL6B,ATF2,ROCK2,PIK3R3,MEF2D,RHOU,IGF1R,PRKAG2",7]
["FLT3 Signaling in Hematopoietic Progenitor Cells",1.93,0.0941,0.707,"PIK3R3,MAPK1,GRB2,FLT3LG,FGFR1,AKT3,FGFR2,ATF2",4]
["Leptin Signaling in Obesity",1.93,0.0941,1.134,"PIK3R3,MAPK1,GRB2,PDE3B,FGFR1,PRKAG2,AKT3,FGFR2",4]
["Superpathway of D-myo-inositol (1,4,5)-trisphosphate Metabolism",1.93,0.16,"NaN","BPNT1,IMPA2,INPP5A,PTEN",1]
["Renin-Angiotensin Signaling",1.93,0.0833,"NaN","PIK3R3,PRKCI,MAPK1,GRB2,FGFR1,PRKAG2,MAPK9,FGFR2,ITPR1,ATF2",4]
["dTMP De Novo Biosynthesis",1.92,0.4,"NaN","SHMT1,SHMT2",0]
["Folate Polyglutamylation",1.92,0.4,"NaN","SHMT1,SHMT2",0]
["Calcium Signaling",1.9,0.073,0.378,"RAP2B,HDAC6,TNNT1,MAPK1,ATP2C1,MEF2D,TNNT2,MEF2A,PRKAG2,RCAN3,MYL6B,ITPR1,ATF2",1]
["Aryl Hydrocarbon Receptor Signaling",1.9,0.0786,-1,"TGM2,GSTT2/GSTT2B,CCNE1,MAPK1,MED1,NFIA,CDKN1A,CDK6,HSP90AA1,CHEK2,CHEK1",6]
["SAPK/JNK Signaling",1.89,0.0865,0.707,"PIK3R3,TRADD,GRB2,CDC42,FGFR1,MAPK8IP2,MAPK9,FGFR2,ATF2",4]
["Sphingosine-1-phosphate Signaling",1.89,0.082,1,"PIK3R3,MAPK1,GRB2,FGFR1,CASP2,CASP1,RHOU,AKT3,FGFR2,ASAH1",6]
["Myc Mediated Apoptosis Signaling",1.89,0.1,"NaN","PIK3R3,GRB2,FGFR1,IGF1R,AKT3,MAPK9,FGFR2",5]
["Gαq Signaling",1.87,0.075,0.905,"ROCK2,PIK3R3,GNG4,IKBKG,PRKCI,MAPK1,GRB2,FGFR1,RHOU,AKT3,FGFR2,ITPR1",5]
["G Beta Gamma Signaling",1.85,0.0909,0.707,"GNG4,PRKCI,MAPK1,GRB2,CDC42,CAV1,PRKAG2,AKT3",5]
["Actin Nucleation by ARP-WASP Complex",1.82,0.107,-0.447,"ROCK2,ITGB1,GRB2,CDC42,WASL,RHOU",1]
["Role of NFAT in Regulation of the Immune Response",1.8,0.071,0.302,"GNG4,MAPK1,GRB2,FGFR1,MEF2A,FGFR2,ITPR1,ATF2,PIK3R3,IKBKG,MEF2D,AKT3,RCAN3",5]
["STAT3 Pathway",1.79,0.0959,2.646,"TGFBR1,MAPK1,FGFR1,CDKN1A,IGF1R,MAPK9,FGFR2",6]
["3-phosphoinositide Biosynthesis",1.79,0.0707,"NaN","MTMR9,GRB2,FGFR1,NUDT12,PPFIA3,FGFR2,STYX,STYXL1,PTEN,PIK3R3,PPM1H,MTMR2,PPM1F",3]
["IL-6 Signaling",1.77,0.0787,0.632,"PIK3R3,CXCL8,IKBKG,MAPK1,GRB2,FGFR1,AKT3,MAPK9,FGFR2,CEBPB",7]
["IL-12 Signaling and Production in Macrophages",1.77,0.0753,"NaN","PIK3R3,IKBKG,PRKCI,MAPK1,GRB2,MYD88,FGFR1,AKT3,MAPK9,FGFR2,CEBPB",7]
["B Cell Receptor Signaling",1.77,0.0703,0.832,"RAP2B,MAPK1,GRB2,FGFR1,MAPK9,FGFR2,ATF2,PTEN,PIK3R3,IKBKG,CDC42,RPS6KB2,AKT3",7]
["Acute Myeloid Leukemia Signaling",1.77,0.0879,0,"PIK3R3,MAPK1,GRB2,FLT3LG,FGFR1,RPS6KB2,AKT3,FGFR2",4]
["TREM1 Signaling",1.73,0.0933,-1.134,"ITGB1,CXCL8,MAPK1,GRB2,MYD88,CASP1,AKT3",5]
["Antiproliferative Role of Somatostatin Receptor 2",1.73,0.0933,0.816,"PIK3R3,GNG4,MAPK1,GRB2,FGFR1,CDKN1A,FGFR2",5]
["Gap Junction Signaling",1.72,0.0714,"NaN","PIK3R3,TUBB3,PRKCI,MAPK1,GRB2,FGFR1,TUBB2A,CAV1,PRKAG2,AKT3,FGFR2,ITPR1",6]
["Corticotropin Releasing Hormone Signaling",1.72,0.0811,-0.378,"PRKCI,GLI2,MAPK1,MEF2D,MEF2A,PRKAG2,PTGS2,ITPR1,ATF2",2]
["Telomerase Signaling",1.72,0.0811,1.134,"HDAC6,PIK3R3,MAPK1,GRB2,FGFR1,CDKN1A,HSP90AA1,AKT3,FGFR2",6]
["Fcγ Receptor-mediated Phagocytosis in Macrophages and Monocytes",1.72,0.086,-0.707,"MYO5A,PIK3R3,PRKCI,MAPK1,CDC42,RPS6KB2,AKT3,PTEN",5]
["CCR3 Signaling in Eosinophils",1.71,0.0769,"NaN","ROCK2,PIK3R3,GNG4,PRKCI,MAPK1,GRB2,FGFR1,FGFR2,LIMK2,ITPR1",4]
["IL-15 Signaling",1.7,0.0921,"NaN","PIK3R3,CXCL8,MAPK1,GRB2,FGFR1,AKT3,FGFR2",5]
["Neurotrophin/TRK Signaling",1.7,0.0921,0.378,"PIK3R3,MAPK1,GRB2,CDC42,FGFR1,FGFR2,ATF2",4]
["BMP signaling pathway",1.7,0.0921,1.134,"MAPK1,GRB2,PRKAG2,MAPK9,SMAD5,BMP6,ATF2",3]
["Acute Phase Response Signaling",1.7,0.071,0.905,"PIK3R3,TRADD,IKBKG,FTL,MAPK1,GRB2,MYD88,AKT3,MAPK9,CEBPB,SERPINE1,CRABP2",6]
["Leukocyte Extravasation Signaling",1.69,0.0667,-0.277,"ITGB1,MAPK1,GRB2,CXCR4,FGFR1,WASL,MAPK9,MLLT4,FGFR2,ROCK2,PIK3R3,PRKCI,CDC42,ARHGAP12",6]
["RAR Activation",1.68,0.0684,"NaN","PBRM1,PIK3R3,NSD1,PRKCI,MAPK1,MED1,PRKAG2,AKT3,MAPK9,SMAD5,CRABP2,CITED2,PTEN",6]
["Angiopoietin Signaling",1.68,0.0909,0,"PIK3R3,IKBKG,GRB2,FGFR1,AKT3,FGFR2,BIRC5",4]
["Paxillin Signaling",1.67,0.0796,0,"ITGB1,PIK3R3,MAPK1,GRB2,CDC42,FGFR1,MAPK9,FGFR2,ITGB8",5]
["P2Y Purigenic Receptor Signaling Pathway",1.67,0.0758,1,"PIK3R3,GNG4,PRKCI,MAPK1,GRB2,FGFR1,PRKAG2,AKT3,FGFR2,ATF2",5]
["Role of Osteoblasts, Osteoclasts and Chondrocytes in Rheumatoid Arthritis",1.66,0.0647,"NaN","ITGB1,FZD10,MAPK1,GRB2,FGFR1,MAPK9,FGFR2,SMAD5,FZD1,PIK3R3,TRADD,IKBKG,AKT3,FZD5,BMP6",6]
["Superpathway of Geranylgeranyldiphosphate Biosynthesis I (via Mevalonate)",1.66,0.176,"NaN","PMVK,HMGCR,GGPS1",0]
["HIF1α Signaling",1.63,0.0783,"NaN","PIK3R3,SLC2A1,MAPK1,GRB2,FGFR1,HSP90AA1,AKT3,MAPK9,FGFR2",6]
["Erythropoietin Signaling",1.62,0.0886,"NaN","PIK3R3,PRKCI,MAPK1,GRB2,FGFR1,AKT3,FGFR2",4]
["Superpathway of Serine and Glycine Biosynthesis I",1.62,0.286,"NaN","SHMT1,SHMT2",0]
["4-1BB Signaling in T Lymphocytes",1.61,0.129,2,"IKBKG,MAPK1,MAPK9,ATF2",2]
["TR/RXR Activation",1.59,0.0816,"NaN","PIK3R3,SLC2A1,GRB2,PDE3B,MED1,FGFR1,AKT3,FGFR2",3]
["ErbB Signaling",1.59,0.0816,"NaN","PIK3R3,PRKCI,MAPK1,GRB2,CDC42,FGFR1,MAPK9,FGFR2",5]
["D-myo-inositol (1,4,5)-trisphosphate Degradation",1.59,0.167,"NaN","BPNT1,IMPA2,INPP5A",0]
["Phospholipase C Signaling",1.59,0.0633,-0.707,"ITGB1,TGM2,HDAC6,GNG4,PRKCI,AHNAK,MAPK1,GRB2,MEF2D,RALB,MEF2A,RHOU,MYL6B,ITPR1,ATF2",3]
["Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses",1.57,0.073,-0.333,"PIK3R3,CXCL8,PRKCI,MAPK1,GRB2,MYD88,FGFR1,CASP1,MAPK9,FGFR2",7]
["Regulation of eIF4 and p70S6K Signaling",1.56,0.0701,0.378,"ITGB1,PIK3R3,MAPK1,GRB2,FGFR1,PAIP1,EIF3J,AKT3,FGFR2,RPS27A,EIF3M",5]
["IL-2 Signaling",1.56,0.0938,0.816,"PIK3R3,MAPK1,GRB2,FGFR1,AKT3,FGFR2",4]
["DNA damage-induced 14-3-3σ Signaling",1.53,0.158,"NaN","CCNE1,AKT3,RAD1",2]
["Thrombopoietin Signaling",1.53,0.0923,0,"PIK3R3,PRKCI,MAPK1,GRB2,FGFR1,FGFR2",3]
["IL-3 Signaling",1.52,0.0843,0.378,"PIK3R3,PRKCI,MAPK1,GRB2,FGFR1,AKT3,FGFR2",4]
["Prolactin Signaling",1.52,0.0843,0,"PIK3R3,PRKCI,MAPK1,GRB2,FGFR1,FGFR2,CEBPB",4]
["Cell Cycle: G2/M DNA Damage Checkpoint Regulation",1.51,0.102,0.447,"CDKN1A,CHEK2,SKP2,PPM1D,CHEK1",4]
["Cancer Drug Resistance By Drug Efflux",1.51,0.102,"NaN","PIK3R3,MAPK1,AKT3,PTGS2,PTEN",5]
["fMLP Signaling in Neutrophils",1.5,0.0744,0,"PIK3R3,GNG4,PRKCI,MAPK1,GRB2,CDC42,FGFR1,FGFR2,ITPR1",5]
["UVA-Induced MAPK Signaling",1.5,0.0784,0,"PIK3R3,TIPARP,MAPK1,GRB2,FGFR1,RPS6KB2,MAPK9,FGFR2",4]
["Mitotic Roles of Polo-Like Kinase",1.5,0.0909,"NaN","HSP90AA1,CDC23,CHEK2,CDC27,RAD21,SMC1A",1]
["Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis",1.49,0.0583,"NaN","CXCL8,FZD10,MAPK1,GRB2,MYD88,FGFR1,FGFR2,MAPK9,FZD1,CEBPB,ATF2,ROCK2,PIK3R3,TRADD,IKBKG,PRKCI,AKT3,FZD5",8]
["RhoA Signaling",1.48,0.0738,3,"ROCK2,SEPT8,NEDD4,IGF1R,ARHGAP12,LIMK2,MYL6B,SEPT6,SEPT2",1]
["Superpathway of Inositol Phosphate Compounds",1.48,0.0625,"NaN","MTMR9,GRB2,FGFR1,PPFIA3,NUDT12,FGFR2,STYX,STYXL1,INPP5A,PTEN,PIK3R3,PPM1H,MTMR2,PPM1F",3]
["Remodeling of Epithelial Adherens Junctions",1.45,0.0882,2,"MET,CDH1,TUBB3,RAB5A,TUBB2A,CBLL1",3]
["Acyl Carrier Protein Metabolism",1.44,1,"NaN","AASDHPPT",0]
["Thiamin Salvage III",1.44,1,"NaN","TPK1",0]
["Asparagine Biosynthesis I",1.44,1,"NaN","ASNS",0]
["D-mannose Degradation",1.44,1,"NaN","MPI",0]
["Amyloid Processing",1.44,0.098,"NaN","MAPK1,PSENEN,PRKAG2,AKT3,APH1B",3]
["IL-4 Signaling",1.42,0.0805,"NaN","PIK3R3,IL13RA1,GRB2,FGFR1,RPS6KB2,AKT3,FGFR2",3]
["ErbB2-ErbB3 Signaling",1.42,0.087,"NaN","PIK3R3,MAPK1,GRB2,FGFR1,FGFR2,PTEN",4]
["Endothelin-1 Signaling",1.41,0.0642,0,"PIK3R3,PRKCI,MAPK1,GRB2,FGFR1,CASP2,CASP1,MAPK9,FGFR2,PTGS2,ITPR1,PAFAH1B3",7]
["VEGF Family Ligand-Receptor Interactions",1.4,0.0795,0.378,"PIK3R3,PRKCI,MAPK1,GRB2,FGFR1,AKT3,FGFR2",4]
["Cdc42 Signaling",1.4,0.0659,1.667,"ITGB1,CDC42BPA,PRKCI,MAPK1,CDC42,WASL,MAPK9,LIMK2,MYL6B,HLA-F,ATF2",3]
["FcγRIIB Signaling in B Lymphocytes",1.38,0.0943,0.447,"PIK3R3,GRB2,FGFR1,MAPK9,FGFR2",3]
["Caveolar-mediated Endocytosis Signaling",1.37,0.0845,"NaN","ITGB1,CD55,ARCN1,RAB5A,CAV1,ITGB8",1]
["CD28 Signaling in T Helper Cells",1.35,0.0698,1,"PIK3R3,IKBKG,GRB2,CDC42,FGFR1,AKT3,MAPK9,FGFR2,ITPR1",5]
["D-myo-inositol (1,4,5,6)-Tetrakisphosphate Biosynthesis",1.35,0.0698,"NaN","MTMR9,NUDT12,PPM1H,PPFIA3,PPM1F,MTMR2,STYXL1,STYX,PTEN",1]
["D-myo-inositol (3,4,5,6)-tetrakisphosphate Biosynthesis",1.35,0.0698,"NaN","MTMR9,NUDT12,PPM1H,PPFIA3,PPM1F,MTMR2,STYXL1,STYX,PTEN",1]
["Protein Ubiquitination Pathway",1.35,0.0588,"NaN","PSMB9,NEDD4,USP12,DNAJC6,CDC23,HSPA5,SKP2,USP31,USP13,USP42,DNAJC18,HSP90AA1,SMURF2,DNAJB1,DNAJB6",3]
["Role of MAPK Signaling in the Pathogenesis of Influenza",1.34,0.0833,"NaN","MAPK1,AKT3,MAPK9,PTGS2,ATF2,PAFAH1B3",4]
["GM-CSF Signaling",1.32,0.0822,0.816,"PIK3R3,MAPK1,GRB2,FGFR1,AKT3,FGFR2",4]
["Embryonic Stem Cell Differentiation into Cardiac Lineages",1.32,0.2,"NaN","SOX2,MESP1",0]
["Glycine Betaine Degradation",1.32,0.2,"NaN","SHMT1,SHMT2",0]
["RhoGDI Signaling",1.3,0.0636,-0.632,"ROCK2,ITGB1,GNG4,CDH2,CDH1,CDC42,WASL,RHOU,ARHGAP12,LIMK2,MYL6B",4]
["PPAR Signaling",1.29,0.0753,-0.378,"IKBKG,MAPK1,GRB2,MED1,HSP90AA1,PTGS2,CITED2",4]
["IL-22 Signaling",1.27,0.125,"NaN","MAPK1,AKT3,MAPK9",3]
["Estrogen-mediated S-phase Entry",1.27,0.125,"NaN","CCNE1,CDKN1A,SKP2",3]
["Clathrin-mediated Endocytosis Signaling",1.27,0.0609,"NaN","ITGB1,MET,PIK3R3,RAB5A,ARRB1,GRB2,CDC42,FGFR1,WASL,FGFR2,ITGB8,MYO1E",4]
["Regulation of Cellular Mechanics by Calpain Protease",1.26,0.0877,"NaN","ITGB1,CCNE1,MAPK1,GRB2,CDK6",3]
["Neuropathic Pain Signaling In Dorsal Horn Neurons",1.26,0.0702,0.707,"PIK3R3,PRKCI,MAPK1,GRB2,FGFR1,PRKAG2,FGFR2,ITPR1",3]
["Role of PI3K/AKT Signaling in the Pathogenesis of Influenza",1.25,0.0789,0.816,"PIK3R3,MAPK1,GRB2,FGFR1,AKT3,FGFR2",4]
["IL-17A Signaling in Gastric Cells",1.22,0.12,"NaN","CXCL8,MAPK1,MAPK9",3]
["p38 MAPK Signaling",1.21,0.0684,0,"TRADD,TGFBR1,ATF1,MEF2D,RPS6KB2,MEF2A,EEF2K,ATF2",1]
["NF-κB Signaling",1.21,0.0611,0.905,"PIK3R3,TRADD,IKBKG,TGFBR1,GRB2,MYD88,FGFR1,IGF1R,AKT3,FGFR2,TBK1",6]
["Role of BRCA1 in DNA Damage Response",1.2,0.0769,0,"PBRM1,ATF1,CDKN1A,RFC1,CHEK2,CHEK1",2]
["Thrombin Signaling",1.19,0.0591,0.905,"ROCK2,PIK3R3,GNG4,PRKCI,MAPK1,GRB2,FGFR1,RHOU,AKT3,FGFR2,MYL6B,ITPR1",5]
["Dermatan Sulfate Biosynthesis",1.19,0.0833,"NaN","CHST2,CHST7,GXYLT1,DSEL,DSE",0]
["Regulation of IL-2 Expression in Activated and Anergic T Lymphocytes",1.18,0.0759,"NaN","IKBKG,TGFBR1,MAPK1,GRB2,MAPK9,TOB1",3]
["Fc Epsilon RI Signaling",1.18,0.0672,0.707,"PIK3R3,PRKCI,MAPK1,GRB2,FGFR1,AKT3,MAPK9,FGFR2",5]
["Role of p14/p19ARF in Tumor Suppression",1.16,0.093,0,"PIK3R3,GRB2,FGFR1,FGFR2",2]
["iCOS-iCOSL Signaling in T Helper Cells",1.16,0.0667,1.134,"PIK3R3,IKBKG,GRB2,FGFR1,AKT3,FGFR2,ITPR1,PTEN",4]
["CREB Signaling in Neurons",1.15,0.0598,1.265,"PIK3R3,GNG4,PRKCI,MAPK1,GRB2,FGFR1,PRKAG2,AKT3,FGFR2,ITPR1,ATF2",5]
["Epoxysqualene Biosynthesis",1.15,0.5,"NaN","SQLE",0]
["Glutamine Degradation I",1.15,0.5,"NaN","GLS",0]
["Cell Cycle Control of Chromosomal Replication",1.14,0.111,"NaN","MCM6,CDK6,CHEK2",1]
["phagosome formation",1.13,0.0656,"NaN","ITGB1,PIK3R3,PRKCI,SCARA3,GRB2,FGFR1,RHOU,FGFR2",2]
["Cholesterol Biosynthesis I",1.11,0.154,"NaN","SQLE,MSMO1",0]
["Mevalonate Pathway I",1.11,0.154,"NaN","PMVK,HMGCR",0]
["Cholesterol Biosynthesis II (via 24,25-dihydrolanosterol)",1.11,0.154,"NaN","SQLE,MSMO1",0]
["Cholesterol Biosynthesis III (via Desmosterol)",1.11,0.154,"NaN","SQLE,MSMO1",0]
["IL-9 Signaling",1.11,0.0889,0,"PIK3R3,GRB2,FGFR1,FGFR2",2]
["VEGF Signaling",1.1,0.068,1.134,"ROCK2,PIK3R3,MAPK1,GRB2,FGFR1,AKT3,FGFR2",4]
["Cell Cycle: G1/S Checkpoint Regulation",1.09,0.0781,0,"HDAC6,CCNE1,CDKN1A,CDK6,SKP2",4]
["3-phosphoinositide Degradation",1.08,0.0616,"NaN","MTMR9,NUDT12,PPM1H,PPFIA3,PPM1F,MTMR2,STYXL1,STYX,PTEN",1]
["Dermatan Sulfate Biosynthesis (Late Stages)",1.08,0.087,"NaN","CHST2,CHST7,DSEL,DSE",0]
["D-myo-inositol-5-phosphate Metabolism",1.07,0.0612,"NaN","MTMR9,NUDT12,PPM1H,PPFIA3,PPM1F,MTMR2,STYXL1,STYX,PTEN",1]
["PI3K Signaling in B Lymphocytes",1.03,0.0625,1.414,"IKBKG,PRKCI,ATF1,MAPK1,AKT3,ITPR1,PTEN,ATF2",3]
["EIF2 Signaling",1.03,0.0567,1.134,"PIK3R3,MAPK1,GRB2,FGFR1,PAIP1,EIF3J,AKT3,FGFR2,RPS27A,RPL31,EIF3M",5]
["Relaxin Signaling",1.03,0.06,"NaN","PIK3R3,GNG4,MAPK1,GRB2,PDE3B,FGFR1,PRKAG2,AKT3,FGFR2",5]
["GNRH Signaling",1.02,0.062,0.707,"PRKCI,MAPK1,GRB2,CDC42,PRKAG2,MAPK9,ITPR1,ATF2",3]
["Xenobiotic Metabolism Signaling",1.02,0.0524,"NaN","MAPK1,MED1,GRB2,CHST7,FGFR1,MAPK9,FGFR2,GCLC,CHST2,PIK3R3,GSTT2/GSTT2B,FTL,PRKCI,HSP90AA1,CITED2",6]
["TNFR1 Signaling",1,0.0816,0,"TRADD,IKBKG,CDC42,CASP2",2]
["p70S6K Signaling",0.991,0.0611,0.707,"PIK3R3,PRKCI,MAPK1,GRB2,FGFR1,AKT3,FGFR2,EEF2K",4]
["Glutathione Biosynthesis",0.981,0.333,"NaN","GCLC",0]
["Methionine Salvage II (Mammalian)",0.981,0.333,"NaN","MTR",0]
["PDGF Signaling",0.971,0.0667,0,"PIK3R3,MAPK1,GRB2,FGFR1,CAV1,FGFR2",4]
["Amyotrophic Lateral Sclerosis Signaling",0.971,0.0631,"NaN","PIK3R3,RAB5A,GRB2,FGFR1,CASP1,AKT3,FGFR2",4]
["IL-1 Signaling",0.954,0.0659,1.342,"GNG4,IKBKG,MAPK1,MYD88,PRKAG2,MAPK9",4]
["PPARα/RXRα Activation",0.953,0.0562,-0.378,"IKBKG,TGFBR1,MAPK1,GRB2,MED1,LPL,PRKAA2,PRKAG2,HSP90AA1,ADIPOR2",4]
["Mismatch Repair in Eukaryotes",0.951,0.125,"NaN","PCNA,RFC1",1]
["Role of JAK1 and JAK3 in γc Cytokine Signaling",0.946,0.0704,"NaN","PIK3R3,MAPK1,GRB2,FGFR1,FGFR2",3]
["Protein Kinase A Signaling",0.937,0.0487,1.291,"AKAP12,GNG4,TGFBR1,MAPK1,ATF1,MYL6B,CDC23,ITPR1,PTP4A1,ATF2,PTEN,ROCK2,PRKCI,HHAT,PDE3B,KDELR3,PRKAG2,PTGS2,CDC27",5]
["Systemic Lupus Erythematosus Signaling",0.936,0.0533,"NaN","PIK3R3,LSM14A,LSM14B,LSM8,MAPK1,GRB2,FGFR1,PRPF4B,AKT3,FGFR2,HLA-F,LSM5",4]
["Basal Cell Carcinoma Signaling",0.927,0.0694,-1.342,"FZD10,GLI2,FZD5,FZD1,BMP6",1]
["Ceramide Signaling",0.921,0.0645,-0.447,"PIK3R3,GRB2,FGFR1,AKT3,FGFR2,NSMAF",3]
["TWEAK Signaling",0.91,0.0882,"NaN","TRADD,IKBKG,TNFRSF12A",0]
["Ephrin B Signaling",0.908,0.0685,"NaN","ROCK2,GNG4,MAPK1,CXCR4,CDC42",3]
["Actin Cytoskeleton Signaling",0.906,0.0526,0.577,"ROCK2,ITGB1,PIK3R3,ABI2,MAPK1,GRB2,CDC42,FGFR1,WASL,FGFR2,LIMK2,MYL6B",4]
["IL-17A Signaling in Fibroblasts",0.882,0.0857,"NaN","IKBKG,MAPK1,CEBPB",2]
["2-ketoglutarate Dehydrogenase Complex",0.864,0.25,"NaN","DHTKD1",0]
["Myo-inositol Biosynthesis",0.864,0.25,"NaN","IMPA2",0]
["Geranylgeranyldiphosphate Biosynthesis",0.864,0.25,"NaN","GGPS1",0]
["CTLA4 Signaling in Cytotoxic T Lymphocytes",0.829,0.0606,"NaN","PIK3R3,GRB2,FGFR1,AP1S2,AKT3,FGFR2",3]
["Wnt/Ca+ pathway",0.824,0.0702,-1,"FZD10,FZD5,FZD1,ATF2",0]
["Dendritic Cell Maturation",0.822,0.0526,1.265,"PIK3R3,IKBKG,MAPK1,GRB2,MYD88,FGFR1,AKT3,MAPK9,FGFR2,ATF2",6]
["VDR/RXR Activation",0.821,0.0641,"NaN","PRKCI,MED1,CDKN1A,CEBPB,IGFBP1",2]
["Cyclins and Cell Cycle Regulation",0.821,0.0641,"NaN","HDAC6,CCNE1,CDKN1A,CDK6,SKP2",4]
["Natural Killer Cell Signaling",0.816,0.0574,"NaN","PIK3R3,PRKCI,MAPK1,GRB2,FGFR1,AKT3,FGFR2",4]
["April Mediated Signaling",0.805,0.0789,"NaN","IKBKG,MAPK1,MAPK9",2]
["Wnt/β-catenin Signaling",0.799,0.0533,-1.633,"SOX2,FZD10,APPL1,CDH2,CDH1,TGFBR1,AKT3,FZD5,FZD1",4]
["Production of Nitric Oxide and Reactive Oxygen Species in Macrophages",0.792,0.0518,0.632,"PIK3R3,IKBKG,PRKCI,MAPK1,GRB2,FGFR1,RHOU,AKT3,MAPK9,FGFR2",5]
["D-myo-inositol (1,3,4)-trisphosphate Biosynthesis",0.792,0.1,"NaN","INPP5A,PTEN",1]
["Tec Kinase Signaling",0.789,0.0529,-0.707,"ITGB1,PIK3R3,GNG4,PRKCI,GRB2,FGFR1,RHOU,MAPK9,FGFR2",4]
["MSP-RON Signaling Pathway",0.786,0.0678,"NaN","PIK3R3,GRB2,FGFR1,FGFR2",2]
["Inhibition of Matrix Metalloproteases",0.781,0.0769,"NaN","SDC1,ADAM12,SDC2",1]
["Creatine-phosphate Biosynthesis",0.775,0.2,"NaN","CKMT1A/CKMT1B",0]
["Lysine Degradation II",0.775,0.2,"NaN","AASDHPPT",0]
["Lysine Degradation V",0.775,0.2,"NaN","AASDHPPT",0]
["Trans, trans-farnesyl Diphosphate Biosynthesis",0.775,0.2,"NaN","GGPS1",0]
["Tyrosine Degradation I",0.775,0.2,"NaN","HPD",0]
["Induction of Apoptosis by HIV1",0.768,0.0667,1,"TRADD,IKBKG,CXCR4,MAPK9",1]
["B Cell Activating Factor Signaling",0.758,0.075,"NaN","IKBKG,MAPK1,MAPK9",2]
["MIF Regulation of Innate Immunity",0.736,0.0732,"NaN","MAPK1,MAPK9,PTGS2",3]
["Mechanisms of Viral Exit from Host Cells",0.736,0.0732,"NaN","NEDD4,PRKCI,CHMP2B",0]
["ERK/MAPK Signaling",0.735,0.0503,0,"ITGB1,PIK3R3,PRKCI,ATF1,MAPK1,GRB2,FGFR1,PRKAG2,FGFR2,ATF2",3]
["Activation of IRF by Cytosolic Pattern Recognition Receptors",0.733,0.0645,1,"IKBKG,MAPK9,TBK1,ATF2",1]
["ERK5 Signaling",0.716,0.0635,-1,"MEF2D,RPS6KB2,MEF2A,ATF2",0]
["UVC-Induced MAPK Signaling",0.715,0.0714,"NaN","PRKCI,MAPK1,MAPK9",2]
["Ceramide Biosynthesis",0.703,0.167,"NaN","SPTLC2",0]
["Pentose Phosphate Pathway (Non-oxidative Branch)",0.703,0.167,"NaN","TKT",0]
["UDP-N-acetyl-D-glucosamine Biosynthesis II",0.703,0.167,"NaN","GFPT1",0]
["Ceramide Degradation",0.703,0.167,"NaN","ASAH1",0]
["Zymosterol Biosynthesis",0.703,0.167,"NaN","MSMO1",0]
["Molybdenum Cofactor Biosynthesis",0.703,0.167,"NaN","GPHN",0]
["GDP-mannose Biosynthesis",0.703,0.167,"NaN","MPI",0]
["Pyrimidine Deoxyribonucleotides De Novo Biosynthesis I",0.697,0.087,"NaN","RRM2,CMPK1",1]
["T Cell Receptor Signaling",0.696,0.055,"NaN","PIK3R3,IKBKG,MAPK1,GRB2,FGFR1,FGFR2",3]
["α-Adrenergic Signaling",0.687,0.0575,0,"GNG4,PRKCI,MAPK1,PRKAG2,ITPR1",2]
["Type I Diabetes Mellitus Signaling",0.684,0.0545,1.342,"TRADD,IKBKG,MAPK1,MYD88,MAPK9,HLA-F",3]
["PXR/RXR Activation",0.683,0.0615,"NaN","PRKAG2,AKT3,IGFBP1,HNF4A",1]
["Role of IL-17F in Allergic Inflammatory Airway Diseases",0.675,0.0682,"NaN","CXCL8,MAPK1,ATF2",2]
["iNOS Signaling",0.675,0.0682,"NaN","IKBKG,MAPK1,MYD88",2]
["Triacylglycerol Biosynthesis",0.675,0.0682,"NaN","MBOAT2,PLPP2,ELOVL6",0]
["Androgen Signaling",0.672,0.0541,"NaN","GNG4,PRKCI,MAPK1,PRKAG2,HSP90AA1,DNAJB1",3]
["Role of JAK family kinases in IL-6-type Cytokine Signaling",0.643,0.08,"NaN","MAPK1,MAPK9",2]
["Role of Oct4 in Mammalian Embryonic Stem Cell Pluripotency",0.637,0.0652,"NaN","SOX2,FAM208A,MEF2A",0]
["Regulation of Actin-based Motility by Rho",0.635,0.0549,-0.447,"ITGB1,CDC42,WASL,RHOU,MYL6B",1]
["CCR5 Signaling in Macrophages",0.623,0.058,"NaN","GNG4,PRKCI,MAPK1,MAPK9",3]
["Agrin Interactions at Neuromuscular Junction",0.623,0.058,"NaN","ITGB1,MAPK1,CDC42,MAPK9",3]
["Death Receptor Signaling",0.622,0.0543,-0.447,"TRADD,IKBKG,TIPARP,CASP2,TBK1",1]
["Chemokine Signaling",0.595,0.0563,1,"ROCK2,MAPK1,CXCR4,LIMK2",1]
["IL-15 Production",0.594,0.0741,"NaN","PRKCI,TWF1",0]
["Airway Pathology in Chronic Obstructive Pulmonary Disease",0.594,0.125,"NaN","CXCL8",1]
["Sphingosine and Sphingosine-1-phosphate Metabolism",0.594,0.125,"NaN","ASAH1",0]
["Histidine Degradation III",0.594,0.125,"NaN","HAL",0]
["Citrulline Biosynthesis",0.594,0.125,"NaN","GLS",0]
["Purine Ribonucleosides Degradation to Ribose-1-phosphate",0.594,0.125,"NaN","PGM2",0]
["Glycoaminoglycan-protein Linkage Region Biosynthesis",0.594,0.125,"NaN","GXYLT1",0]
["Sphingomyelin Metabolism",0.594,0.125,"NaN","SGMS1",0]
["Gαi Signaling",0.575,0.05,"NaN","GNG4,MAPK1,GRB2,RALB,CAV1,PRKAG2",4]
["phagosome maturation",0.575,0.05,"NaN","TUBB3,RAB5A,PRDX1,TUBB2A,SNAP25,ATP6V1B2",1]
["TNFR2 Signaling",0.55,0.069,"NaN","IKBKG,TBK1",0]
["Prostanoid Biosynthesis",0.55,0.111,"NaN","PTGS2",1]
["Phosphatidylethanolamine Biosynthesis II",0.55,0.111,"NaN","ETNK1",0]
["GDP-glucose Biosynthesis",0.55,0.111,"NaN","PGM2",0]
["Heparan Sulfate Biosynthesis",0.543,0.0533,"NaN","CHST2,CHST7,GXYLT1,GLCE",0]
["Sonic Hedgehog Signaling",0.53,0.0667,"NaN","GLI2,PRKAG2",0]
["Sperm Motility",0.527,0.048,1.342,"PRKCI,TWF1,SLC12A2,PRKAG2,ITPR1,PAFAH1B3",0]
["Glucose and Glucose-1-phosphate Degradation",0.512,0.1,"NaN","PGM2",0]
["Calcium Transport I",0.512,0.1,"NaN","ATP2C1",0]
["Pentose Phosphate Pathway",0.512,0.1,"NaN","TKT",0]
["Histidine Degradation VI",0.512,0.1,"NaN","HAL",0]
["Antioxidant Action of Vitamin C",0.502,0.0485,-2,"IKBKG,SLC2A1,MAPK1,MAPK9,PAFAH1B3",2]
["Estrogen Receptor Signaling",0.5,0.0469,"NaN","TAF1,MAPK1,GRB2,MED1,HNRNPD,IGFBP1",1]
["Pyrimidine Ribonucleotides Interconversion",0.492,0.0625,"NaN","CMPK1,ENTPD7",0]
["PKCθ Signaling in T Lymphocytes",0.483,0.0462,0.816,"PIK3R3,IKBKG,MAPK1,GRB2,FGFR1,FGFR2",3]
["Glycogen Degradation II",0.478,0.0909,"NaN","PGM2",0]
["Dolichyl-diphosphooligosaccharide Biosynthesis",0.478,0.0909,"NaN","ALG5",0]
["Circadian Rhythm Signaling",0.474,0.0606,"NaN","BHLHE41,ATF2",0]
["MIF-mediated Glucocorticoid Regulation",0.474,0.0606,"NaN","MAPK1,PTGS2",2]
["Hepatic Fibrosis / Hepatic Stellate Cell Activation",0.467,0.0437,"NaN","MET,CXCL8,TGFBR1,FGFR1,IGF1R,FGFR2,MYL6B,SERPINE1",5]
["Oncostatin M Signaling",0.457,0.0588,"NaN","MAPK1,GRB2",1]
["Pyrimidine Ribonucleotides De Novo Biosynthesis",0.457,0.0588,"NaN","CMPK1,ENTPD7",0]
["Chondroitin Sulfate Biosynthesis",0.457,0.0517,"NaN","CHST2,CHST7,GXYLT1",0]
["Hepatic Cholestasis",0.455,0.044,"NaN","CXCL8,IKBKG,PRKCI,MYD88,PRKAG2,MAPK9,HNF4A",3]
["Acyl-CoA Hydrolysis",0.448,0.0833,"NaN","HNF4A",0]
["BER pathway",0.448,0.0833,"NaN","PCNA",1]
["Coagulation System",0.441,0.0571,"NaN","PLAUR,SERPINE1",0]
["GPCR-Mediated Nutrient Sensing in Enteroendocrine Cells",0.434,0.0471,"NaN","GNG4,PRKCI,PRKAG2,ITPR1",1]
["Stearate Biosynthesis I (Animals)",0.426,0.0556,"NaN","HNF4A,ELOVL6",0]
["autophagy",0.426,0.0556,"NaN","STX17,ATG10",0]
["HIPPO signaling",0.424,0.0465,"NaN","DLG5,SMAD5,PATJ,SKP2",1]
["Role of IL-17A in Psoriasis",0.42,0.0769,"NaN","CXCL8",1]
["Glycogen Degradation III",0.42,0.0769,"NaN","PGM2",0]
["NAD Phosphorylation and Dephosphorylation",0.42,0.0769,"NaN","NNT",0]
["Bile Acid Biosynthesis, Neutral Pathway",0.42,0.0769,"NaN","AKR1C4",0]
["Bladder Cancer Signaling",0.415,0.046,"NaN","CXCL8,CDH1,MAPK1,CDKN1A",4]
["Antigen Presentation Pathway",0.411,0.0541,"NaN","PSMB9,HLA-F",0]
["Complement System",0.411,0.0541,"NaN","CD55,CD46",0]
["Notch Signaling",0.397,0.0526,"NaN","PSENEN,APH1B",1]
["Androgen Biosynthesis",0.395,0.0714,"NaN","AKR1C4",0]
["Superpathway of Citrulline Metabolism",0.395,0.0714,"NaN","GLS",0]
["Phenylalanine Degradation IV (Mammalian, via Side Chain)",0.395,0.0714,"NaN","HPD",0]
["Colanic Acid Building Blocks Biosynthesis",0.395,0.0714,"NaN","MPI",0]
["Calcium-induced T Lymphocyte Apoptosis",0.389,0.0469,"NaN","PRKCI,MEF2D,ITPR1",0]
["Hypoxia Signaling in the Cardiovascular System",0.379,0.0462,"NaN","HSP90AA1,PTEN,ATF2",2]
["Vitamin-C Transport",0.373,0.0667,"NaN","SLC2A1",0]
["Role of PKR in Interferon Induction and Antiviral Response",0.37,0.05,"NaN","IKBKG,ATF2",0]
["Thyroid Cancer Signaling",0.37,0.05,"NaN","CDH1,MAPK1",2]
["Neuroprotective Role of THOP1 in Alzheimer's Disease",0.37,0.05,"NaN","PRKAG2,HLA-F",0]
["Transcriptional Regulatory Network in Embryonic Stem Cells",0.37,0.05,"NaN","SOX2,HNF4A",0]
["Synaptic Long Term Potentiation",0.359,0.0417,1.342,"PRKCI,MAPK1,PRKAG2,ITPR1,ATF2",1]
["Heparan Sulfate Biosynthesis (Late Stages)",0.359,0.0448,"NaN","CHST2,CHST7,GLCE",0]
["GABA Receptor Signaling",0.359,0.0448,"NaN","GABRB3,GABARAP,GPHN",0]
["γ-glutamyl Cycle",0.352,0.0625,"NaN","GCLC",0]
["Parkinson's Signaling",0.352,0.0625,"NaN","MAPK1",1]
["Gustation Pathway",0.346,0.041,"NaN","PDE3B,ASIC1,PRKAG2,ITPR1,PANX1",0]
["Role of RIG1-like Receptors in Antiviral Innate Immunity",0.334,0.0465,"NaN","IKBKG,TBK1",0]
["Mitochondrial L-carnitine Shuttle Pathway",0.333,0.0588,"NaN","CPT1C",0]
["Triacylglycerol Degradation",0.323,0.0455,"NaN","LPL,ABHD2",0]
["Melatonin Signaling",0.323,0.0423,"NaN","PRKCI,MAPK1,PRKAG2",1]
["FXR/RXR Activation",0.319,0.0397,"NaN","SDC1,LPL,AKT3,MAPK9,HNF4A",2]
["CDK5 Signaling",0.317,0.0404,"NaN","ITGB1,MAPK1,PRKAG2,MAPK9",2]
["Atherosclerosis Signaling",0.313,0.0394,"NaN","CXCL8,CXCR4,LPL,TNFRSF12A,PAFAH1B3",1]
["Toll-like Receptor Signaling",0.299,0.0405,"NaN","IKBKG,MAPK1,MYD88",2]
["Glutathione Redox Reactions I",0.299,0.0526,"NaN","GSTT2/GSTT2B",0]
["G-Protein Coupled Receptor Signaling",0.29,0.037,"NaN","PIK3R3,IKBKG,MAPK1,GRB2,PDE3B,FGFR1,PRKAG2,AKT3,FGFR2,ATF2",4]
["Role of Wnt/GSK-3β Signaling in the Pathogenesis of Influenza",0.283,0.0395,"NaN","FZD10,FZD5,FZD1",0]
["Cardiomyocyte Differentiation via BMP Receptors",0.283,0.05,"NaN","ATF2",0]
["DNA Methylation and Transcriptional Repression Signaling",0.283,0.05,"NaN","SAP18",0]
["1D-myo-inositol Hexakisphosphate Biosynthesis II (Mammalian)",0.283,0.05,"NaN","INPP5A",0]
["Chondroitin Sulfate Biosynthesis (Late Stages)",0.274,0.0408,"NaN","CHST2,CHST7",0]
["Dopamine-DARPP32 Feedback in cAMP Signaling",0.273,0.037,0,"KCNJ12,PRKCI,ATF1,PRKAG2,ITPR1,ATF2",0]
["Maturity Onset Diabetes of Young (MODY) Signaling",0.269,0.0476,"NaN","HNF4A",0]
["Endoplasmic Reticulum Stress Pathway",0.269,0.0476,"NaN","HSPA5",1]
["Fatty Acid α-oxidation",0.256,0.0455,"NaN","PTGS2",1]
["Gαs Signaling",0.254,0.0367,"NaN","GNG4,MAPK1,PRKAG2,ATF2",2]
["CD27 Signaling in Lymphocytes",0.248,0.0385,"NaN","IKBKG,MAPK9",1]
["TCA Cycle II (Eukaryotic)",0.243,0.0435,"NaN","DHTKD1",0]
["Unfolded protein response",0.233,0.037,"NaN","CEBPB,HSPA5",2]
["CDP-diacylglycerol Biosynthesis I",0.232,0.0417,"NaN","MBOAT2",0]
["Lipid Antigen Presentation by CD1",0.211,0.0385,"NaN","PSAP",0]
["NAD Salvage Pathway II",0.211,0.0385,"NaN","NUDT12",0]
["Phosphatidylglycerol Biosynthesis II (Non-plastidic)",0.211,0.0385,"NaN","MBOAT2",0]

{"sheet":"Detail","index":1,"n_rows":2594,"n_cols":14,"rows_kept":2594,"flags":["formulas_cached_only"]}
["Ingenuity Canonical Pathways"," -log(p-value)","Ratio","z-score","Molecules","Entrez Gene Name","Location","Type(s)","Corrected_p-value","P value","Regulation","FCAbsolute","Fold_Change","Log_FC"]
["HER-2 Signaling in Breast Cancer",4.8,0.148,"NaN","ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["HER-2 Signaling in Breast Cancer",4.8,0.148,"NaN","TSC1","tuberous sclerosis 1","Cytoplasm","other",0.0020370672,0.0010299383,"up",1.3084451,1.3084451,0.38785338]
["HER-2 Signaling in Breast Cancer",4.8,0.148,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["HER-2 Signaling in Breast Cancer",4.8,0.148,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["HER-2 Signaling in Breast Cancer",4.8,0.148,"NaN","CDK6","cyclin-dependent kinase 6","Nucleus","kinase",0.0011555209,0.0002428485,"down",1.6726129,-1.6726129,-0.7421036]
["HER-2 Signaling in Breast Cancer",4.8,0.148,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["HER-2 Signaling in Breast Cancer",4.8,0.148,"NaN","ITGB8","integrin subunit beta 8","Plasma Membrane","other",0.0039384346,0.0026866843,"up",1.8310404,1.8310404,0.8726636]
["HER-2 Signaling in Breast Cancer",4.8,0.148,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["HER-2 Signaling in Breast Cancer",4.8,0.148,"NaN","CCNE1","cyclin E1","Nucleus","transcription regulator",0.0013342145,0.00036659295,"down",2.6488216,-2.6488216,-1.4053507]
["HER-2 Signaling in Breast Cancer",4.8,0.148,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["HER-2 Signaling in Breast Cancer",4.8,0.148,"NaN","CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["HER-2 Signaling in Breast Cancer",4.8,0.148,"NaN","CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["HER-2 Signaling in Breast Cancer",4.8,0.148,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Germ Cell-Sertoli Cell Junction Signaling",4.78,0.11,"NaN","ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["Germ Cell-Sertoli Cell Junction Signaling",4.78,0.11,"NaN","TUBB3","tubulin beta 3 class III","Cytoplasm","other",0.001459056,0.00047059942,"up",1.4351482,1.4351482,0.52119976]
["Germ Cell-Sertoli Cell Junction Signaling",4.78,0.11,"NaN","TGFBR1","transforming growth factor beta receptor 1","Plasma Membrane","kinase",0.0008942897,0.00011058827,"up",1.5758384,1.5758384,0.65611964]
["Germ Cell-Sertoli Cell Junction Signaling",4.78,0.11,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Germ Cell-Sertoli Cell Junction Signaling",4.78,0.11,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Germ Cell-Sertoli Cell Junction Signaling",4.78,0.11,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Germ Cell-Sertoli Cell Junction Signaling",4.78,0.11,"NaN","WASL","Wiskott-Aldrich syndrome like","Cytoplasm","other",0.00040977335,6.54692e-06,"up",1.4019742,1.4019742,0.4874598]
["Germ Cell-Sertoli Cell Junction Signaling",4.78,0.11,"NaN","TUBB2A","tubulin beta 2A class IIa","Cytoplasm","other",0.0026605518,0.0015617278,"up",1.4475315,1.4475315,0.5335947]
["Germ Cell-Sertoli Cell Junction Signaling",4.78,0.11,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Germ Cell-Sertoli Cell Junction Signaling",4.78,0.11,"NaN","MLLT4","myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4","Nucleus","other",0.0013056329,0.00034460775,"up",1.7435131,1.7435131,0.8019972]
["Germ Cell-Sertoli Cell Junction Signaling",4.78,0.11,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Germ Cell-Sertoli Cell Junction Signaling",4.78,0.11,"NaN","LIMK2","LIM domain kinase 2","Cytoplasm","kinase",0.0035328772,0.002318736,"up",1.3875531,1.3875531,0.47254297]
["Germ Cell-Sertoli Cell Junction Signaling",4.78,0.11,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Germ Cell-Sertoli Cell Junction Signaling",4.78,0.11,"NaN","CDH1","cadherin 1","Plasma Membrane","other",0.0017019173,0.0006999703,"up",1.452055,1.452055,0.5380961]
["Germ Cell-Sertoli Cell Junction Signaling",4.78,0.11,"NaN","CDH2","cadherin 2","Plasma Membrane","other",0.001091852,0.00020167766,"up",1.3591936,1.3591936,0.44275093]
["Germ Cell-Sertoli Cell Junction Signaling",4.78,0.11,"NaN","CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["Germ Cell-Sertoli Cell Junction Signaling",4.78,0.11,"NaN","RHOU","ras homolog family member U","Cytoplasm","enzyme",0.0009194498,0.00012193339,"down",1.7715495,-1.7715495,-0.82501173]
["Germ Cell-Sertoli Cell Junction Signaling",4.78,0.11,"NaN","MTMR2","myotubularin related protein 2","Cytoplasm","phosphatase",0.001395873,0.000419132,"up",1.3830658,1.3830658,0.46786982]
["Germ Cell-Sertoli Cell Junction Signaling",4.78,0.11,"NaN","NECTIN2","nectin cell adhesion molecule 2","Plasma Membrane","transmembrane receptor",0.0023623689,0.0013073402,"up",1.3960435,1.3960435,0.48134392]
["Glioblastoma Multiforme Signaling",4.74,0.113,-0.258,"TSC1","tuberous sclerosis 1","Cytoplasm","other",0.0020370672,0.0010299383,"up",1.3084451,1.3084451,0.38785338]
["Glioblastoma Multiforme Signaling",4.74,0.113,-0.258,"FZD10","frizzled class receptor 10","Plasma Membrane","G-protein coupled receptor",0.00084399927,9.184798e-05,"down",1.4670624,-1.4670624,-0.5529302]
["Glioblastoma Multiforme Signaling",4.74,0.113,-0.258,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Glioblastoma Multiforme Signaling",4.74,0.113,-0.258,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Glioblastoma Multiforme Signaling",4.74,0.113,-0.258,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Glioblastoma Multiforme Signaling",4.74,0.113,-0.258,"CDK6","cyclin-dependent kinase 6","Nucleus","kinase",0.0011555209,0.0002428485,"down",1.6726129,-1.6726129,-0.7421036]
["Glioblastoma Multiforme Signaling",4.74,0.113,-0.258,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Glioblastoma Multiforme Signaling",4.74,0.113,-0.258,"ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["Glioblastoma Multiforme Signaling",4.74,0.113,-0.258,"FZD1","frizzled class receptor 1","Plasma Membrane","G-protein coupled receptor",0.0036817046,0.002460812,"down",1.529664,-1.529664,-0.6132148]
["Glioblastoma Multiforme Signaling",4.74,0.113,-0.258,"PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["Glioblastoma Multiforme Signaling",4.74,0.113,-0.258,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Glioblastoma Multiforme Signaling",4.74,0.113,-0.258,"CCNE1","cyclin E1","Nucleus","transcription regulator",0.0013342145,0.00036659295,"down",2.6488216,-2.6488216,-1.4053507]
["Glioblastoma Multiforme Signaling",4.74,0.113,-0.258,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["Glioblastoma Multiforme Signaling",4.74,0.113,-0.258,"CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["Glioblastoma Multiforme Signaling",4.74,0.113,-0.258,"IGF1R","insulin like growth factor 1 receptor","Plasma Membrane","transmembrane receptor",0.0016147236,0.0006161828,"up",1.8701973,1.8701973,0.90319043]
["Glioblastoma Multiforme Signaling",4.74,0.113,-0.258,"RHOU","ras homolog family member U","Cytoplasm","enzyme",0.0009194498,0.00012193339,"down",1.7715495,-1.7715495,-0.82501173]
["Glioblastoma Multiforme Signaling",4.74,0.113,-0.258,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Glioblastoma Multiforme Signaling",4.74,0.113,-0.258,"FZD5","frizzled class receptor 5","Plasma Membrane","G-protein coupled receptor",0.0011555209,0.00024123449,"down",1.5153433,-1.5153433,-0.59964466]
["Melanoma Signaling",4.62,0.182,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Melanoma Signaling",4.62,0.182,"NaN","CDH1","cadherin 1","Plasma Membrane","other",0.0017019173,0.0006999703,"up",1.452055,1.452055,0.5380961]
["Melanoma Signaling",4.62,0.182,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Melanoma Signaling",4.62,0.182,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Melanoma Signaling",4.62,0.182,"NaN","MITF","microphthalmia-associated transcription factor","Nucleus","transcription regulator",0.0009366118,0.00012626672,"up",1.3044807,1.3044807,0.38347557]
["Melanoma Signaling",4.62,0.182,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Melanoma Signaling",4.62,0.182,"NaN","CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["Melanoma Signaling",4.62,0.182,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Melanoma Signaling",4.62,0.182,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Melanoma Signaling",4.62,0.182,"NaN","PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["PTEN Signaling",4.59,0.126,-1.069,"ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["PTEN Signaling",4.59,0.126,-1.069,"TGFBR1","transforming growth factor beta receptor 1","Plasma Membrane","kinase",0.0008942897,0.00011058827,"up",1.5758384,1.5758384,0.65611964]
["PTEN Signaling",4.59,0.126,-1.069,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["PTEN Signaling",4.59,0.126,-1.069,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["PTEN Signaling",4.59,0.126,-1.069,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["PTEN Signaling",4.59,0.126,-1.069,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["PTEN Signaling",4.59,0.126,-1.069,"CNKSR3","CNKSR family member 3","Plasma Membrane","kinase",0.0006943628,4.4579963e-05,"down",2.208642,-2.208642,-1.1431596]
["PTEN Signaling",4.59,0.126,-1.069,"PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["PTEN Signaling",4.59,0.126,-1.069,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["PTEN Signaling",4.59,0.126,-1.069,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["PTEN Signaling",4.59,0.126,-1.069,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["PTEN Signaling",4.59,0.126,-1.069,"CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["PTEN Signaling",4.59,0.126,-1.069,"RPS6KB2","ribosomal protein S6 kinase B2","Cytoplasm","kinase",0.0016431456,0.0006520507,"down",1.986918,-1.986918,-0.9905323]
["PTEN Signaling",4.59,0.126,-1.069,"IGF1R","insulin like growth factor 1 receptor","Plasma Membrane","transmembrane receptor",0.0016147236,0.0006161828,"up",1.8701973,1.8701973,0.90319043]
["PTEN Signaling",4.59,0.126,-1.069,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["IGF-1 Signaling",4.56,0.132,0.577,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["IGF-1 Signaling",4.56,0.132,0.577,"NEDD4","neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase","Cytoplasm","enzyme",0.00067191356,4.1885378e-05,"up",2.6203134,2.6203134,1.3897394]
["IGF-1 Signaling",4.56,0.132,0.577,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["IGF-1 Signaling",4.56,0.132,0.577,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["IGF-1 Signaling",4.56,0.132,0.577,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["IGF-1 Signaling",4.56,0.132,0.577,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["IGF-1 Signaling",4.56,0.132,0.577,"IGF1R","insulin like growth factor 1 receptor","Plasma Membrane","transmembrane receptor",0.0016147236,0.0006161828,"up",1.8701973,1.8701973,0.90319043]
["IGF-1 Signaling",4.56,0.132,0.577,"RPS6KB2","ribosomal protein S6 kinase B2","Cytoplasm","kinase",0.0016431456,0.0006520507,"down",1.986918,-1.986918,-0.9905323]
["IGF-1 Signaling",4.56,0.132,0.577,"PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["IGF-1 Signaling",4.56,0.132,0.577,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["IGF-1 Signaling",4.56,0.132,0.577,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["IGF-1 Signaling",4.56,0.132,0.577,"IGFBP1","insulin like growth factor binding protein 1","Extracellular Space","other",0.0010769006,0.00018458503,"down",1.3619553,-1.3619553,-0.44567934]
["IGF-1 Signaling",4.56,0.132,0.577,"CYR61","cysteine rich angiogenic inducer 61","Extracellular Space","other",0.0014103054,0.00042576404,"up",1.6788704,1.6788704,0.7474909]
["IGF-1 Signaling",4.56,0.132,0.577,"GRB10","growth factor receptor bound protein 10","Cytoplasm","other",0.0012233602,0.00028852653,"up",1.7130156,1.7130156,0.77653825]
["p53 Signaling",4.33,0.126,-1.508,"GADD45B","growth arrest and DNA damage inducible beta","Cytoplasm","other",0.0013662435,0.00038785784,"up",1.6800824,1.6800824,0.748532]
["p53 Signaling",4.33,0.126,-1.508,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["p53 Signaling",4.33,0.126,-1.508,"MED1","mediator complex subunit 1","Nucleus","transcription regulator",0.007830824,0.006407651,"down",1.3726159,-1.3726159,-0.456928]
["p53 Signaling",4.33,0.126,-1.508,"PLAGL1","PLAG1 like zinc finger 1","Nucleus","transcription regulator",0.0025946551,0.0015018159,"down",1.3273312,-1.3273312,-0.4085284]
["p53 Signaling",4.33,0.126,-1.508,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["p53 Signaling",4.33,0.126,-1.508,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["p53 Signaling",4.33,0.126,-1.508,"BIRC5","baculoviral IAP repeat containing 5","Cytoplasm","other",0.0018505693,0.00084797834,"up",1.5707992,1.5707992,0.6514988]
["p53 Signaling",4.33,0.126,-1.508,"PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["p53 Signaling",4.33,0.126,-1.508,"CHEK1","checkpoint kinase 1","Nucleus","kinase",0.0010877973,0.00019520131,"up",1.4226359,1.4226359,0.5085665]
["p53 Signaling",4.33,0.126,-1.508,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["p53 Signaling",4.33,0.126,-1.508,"PCNA","proliferating cell nuclear antigen","Nucleus","enzyme",0.0032386743,0.0020517183,"down",1.3257968,-1.3257968,-0.40685973]
["p53 Signaling",4.33,0.126,-1.508,"CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["p53 Signaling",4.33,0.126,-1.508,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["p53 Signaling",4.33,0.126,-1.508,"CHEK2","checkpoint kinase 2","Nucleus","kinase",0.0028598784,0.0017272087,"up",1.3150214,1.3150214,0.39508626]
["Type II Diabetes Mellitus Signaling",4.26,0.118,0.535,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Type II Diabetes Mellitus Signaling",4.26,0.118,0.535,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Type II Diabetes Mellitus Signaling",4.26,0.118,0.535,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Type II Diabetes Mellitus Signaling",4.26,0.118,0.535,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Type II Diabetes Mellitus Signaling",4.26,0.118,0.535,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Type II Diabetes Mellitus Signaling",4.26,0.118,0.535,"CEBPB","CCAAT/enhancer binding protein beta","Nucleus","transcription regulator",0.021593252,0.020254135,"down",1.3026826,-1.3026826,-0.38148564]
["Type II Diabetes Mellitus Signaling",4.26,0.118,0.535,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Type II Diabetes Mellitus Signaling",4.26,0.118,0.535,"TRADD","TNFRSF1A associated via death domain","Cytoplasm","other",0.0016301863,0.0006398275,"up",1.3732907,1.3732907,0.457637]
["Type II Diabetes Mellitus Signaling",4.26,0.118,0.535,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["Type II Diabetes Mellitus Signaling",4.26,0.118,0.535,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Type II Diabetes Mellitus Signaling",4.26,0.118,0.535,"PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Type II Diabetes Mellitus Signaling",4.26,0.118,0.535,"PRKAA2","protein kinase AMP-activated catalytic subunit alpha 2","Cytoplasm","kinase",0.0014867174,0.0005054725,"up",1.3466656,1.3466656,0.42939165]
["Type II Diabetes Mellitus Signaling",4.26,0.118,0.535,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Type II Diabetes Mellitus Signaling",4.26,0.118,0.535,"ADIPOR2","adiponectin receptor 2","Plasma Membrane","other",0.00089824985,0.00011682664,"up",1.4429079,1.4429079,0.52897924]
["Type II Diabetes Mellitus Signaling",4.26,0.118,0.535,"NSMAF","neutral sphingomyelinase activation associated factor","Cytoplasm","other",0.0006942706,4.3952532e-05,"down",3.3836162,-3.3836162,-1.7585659]
["HGF Signaling",4.16,0.122,0.832,"ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["HGF Signaling",4.16,0.122,0.832,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["HGF Signaling",4.16,0.122,0.832,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["HGF Signaling",4.16,0.122,0.832,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["HGF Signaling",4.16,0.122,0.832,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["HGF Signaling",4.16,0.122,0.832,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["HGF Signaling",4.16,0.122,0.832,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["HGF Signaling",4.16,0.122,0.832,"MET","MET proto-oncogene, receptor tyrosine kinase","Plasma Membrane","kinase",0.0008691947,0.00010051858,"up",1.5833938,1.5833938,0.66302013]
["HGF Signaling",4.16,0.122,0.832,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["HGF Signaling",4.16,0.122,0.832,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["HGF Signaling",4.16,0.122,0.832,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["HGF Signaling",4.16,0.122,0.832,"CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["HGF Signaling",4.16,0.122,0.832,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["HGF Signaling",4.16,0.122,0.832,"PTGS2","prostaglandin-endoperoxide synthase 2","Cytoplasm","enzyme",0.0012584343,0.00031259237,"down",1.4767396,-1.4767396,-0.5624155]
["Gα12/13 Signaling",4.14,0.115,0.258,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Gα12/13 Signaling",4.14,0.115,0.258,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Gα12/13 Signaling",4.14,0.115,0.258,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Gα12/13 Signaling",4.14,0.115,0.258,"MEF2A","myocyte enhancer factor 2A","Nucleus","transcription regulator",0.015937602,0.014585446,"down",1.3274704,-1.3274704,-0.40867972]
["Gα12/13 Signaling",4.14,0.115,0.258,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Gα12/13 Signaling",4.14,0.115,0.258,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Gα12/13 Signaling",4.14,0.115,0.258,"MYL6B","myosin light chain 6B","Cytoplasm","other",0.0037700427,0.0025393397,"up",1.3426967,1.3426967,0.4251334]
["Gα12/13 Signaling",4.14,0.115,0.258,"ROCK2","Rho associated coiled-coil containing protein kinase 2","Cytoplasm","kinase",0.0010184328,0.00016622998,"up",1.3479002,1.3479002,0.43071362]
["Gα12/13 Signaling",4.14,0.115,0.258,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Gα12/13 Signaling",4.14,0.115,0.258,"CDH2","cadherin 2","Plasma Membrane","other",0.001091852,0.00020167766,"up",1.3591936,1.3591936,0.44275093]
["Gα12/13 Signaling",4.14,0.115,0.258,"CDH1","cadherin 1","Plasma Membrane","other",0.0017019173,0.0006999703,"up",1.452055,1.452055,0.5380961]
["Gα12/13 Signaling",4.14,0.115,0.258,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["Gα12/13 Signaling",4.14,0.115,0.258,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["Gα12/13 Signaling",4.14,0.115,0.258,"MEF2D","myocyte enhancer factor 2D","Nucleus","transcription regulator",0.0006217929,3.203251e-05,"down",1.3555743,-1.3555743,-0.43890414]
["Gα12/13 Signaling",4.14,0.115,0.258,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["ILK Signaling",4.03,0.0969,0.728,"ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["ILK Signaling",4.03,0.0969,0.728,"FBLIM1","filamin binding LIM protein 1","Plasma Membrane","other",0.0023239863,0.001282043,"up",1.3533263,1.3533263,0.43650976]
["ILK Signaling",4.03,0.0969,0.728,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["ILK Signaling",4.03,0.0969,0.728,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["ILK Signaling",4.03,0.0969,0.728,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["ILK Signaling",4.03,0.0969,0.728,"FERMT2","fermitin family member 2","Cytoplasm","other",0.0009735221,0.00014464476,"down",1.304181,-1.304181,-0.38314408]
["ILK Signaling",4.03,0.0969,0.728,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["ILK Signaling",4.03,0.0969,0.728,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["ILK Signaling",4.03,0.0969,0.728,"MYL6B","myosin light chain 6B","Cytoplasm","other",0.0037700427,0.0025393397,"up",1.3426967,1.3426967,0.4251334]
["ILK Signaling",4.03,0.0969,0.728,"ITGB8","integrin subunit beta 8","Plasma Membrane","other",0.0039384346,0.0026866843,"up",1.8310404,1.8310404,0.8726636]
["ILK Signaling",4.03,0.0969,0.728,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["ILK Signaling",4.03,0.0969,0.728,"PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["ILK Signaling",4.03,0.0969,0.728,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["ILK Signaling",4.03,0.0969,0.728,"CDH1","cadherin 1","Plasma Membrane","other",0.0017019173,0.0006999703,"up",1.452055,1.452055,0.5380961]
["ILK Signaling",4.03,0.0969,0.728,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["ILK Signaling",4.03,0.0969,0.728,"RHOU","ras homolog family member U","Cytoplasm","enzyme",0.0009194498,0.00012193339,"down",1.7715495,-1.7715495,-0.82501173]
["ILK Signaling",4.03,0.0969,0.728,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["ILK Signaling",4.03,0.0969,0.728,"RSU1","Ras suppressor protein 1","Cytoplasm","other",0.0022685104,0.0012299977,"up",1.397716,1.397716,0.4830713]
["ILK Signaling",4.03,0.0969,0.728,"PTGS2","prostaglandin-endoperoxide synthase 2","Cytoplasm","enzyme",0.0012584343,0.00031259237,"down",1.4767396,-1.4767396,-0.5624155]
["Molecular Mechanisms of Cancer",3.99,0.0775,"NaN","RAP2B","RAP2B, member of RAS oncogene family","Plasma Membrane","enzyme",0.0005464768,1.2239901e-05,"down",1.9869581,-1.9869581,-0.9905615]
["Molecular Mechanisms of Cancer",3.99,0.0775,"NaN","FZD10","frizzled class receptor 10","Plasma Membrane","G-protein coupled receptor",0.00084399927,9.184798e-05,"down",1.4670624,-1.4670624,-0.5529302]
["Molecular Mechanisms of Cancer",3.99,0.0775,"NaN","TGFBR1","transforming growth factor beta receptor 1","Plasma Membrane","kinase",0.0008942897,0.00011058827,"up",1.5758384,1.5758384,0.65611964]
["Molecular Mechanisms of Cancer",3.99,0.0775,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Molecular Mechanisms of Cancer",3.99,0.0775,"NaN","PSENEN","presenilin enhancer gamma secretase subunit","Plasma Membrane","peptidase",0.0017462111,0.00074735825,"up",1.374307,1.374307,0.45870435]
["Molecular Mechanisms of Cancer",3.99,0.0775,"NaN","SMAD5","SMAD family member 5","Nucleus","transcription regulator",0.0014749195,0.00048909907,"down",1.3112969,-1.3112969,-0.3909944]
["Molecular Mechanisms of Cancer",3.99,0.0775,"NaN","FZD1","frizzled class receptor 1","Plasma Membrane","G-protein coupled receptor",0.0036817046,0.002460812,"down",1.529664,-1.529664,-0.6132148]
["Molecular Mechanisms of Cancer",3.99,0.0775,"NaN","CHEK1","checkpoint kinase 1","Nucleus","kinase",0.0010877973,0.00019520131,"up",1.4226359,1.4226359,0.5085665]
["Molecular Mechanisms of Cancer",3.99,0.0775,"NaN","HHAT","hedgehog acyltransferase","Cytoplasm","enzyme",0.001277893,0.00032523135,"up",2.8401747,2.8401747,1.5059797]
["Molecular Mechanisms of Cancer",3.99,0.0775,"NaN","RHOU","ras homolog family member U","Cytoplasm","enzyme",0.0009194498,0.00012193339,"down",1.7715495,-1.7715495,-0.82501173]
["Molecular Mechanisms of Cancer",3.99,0.0775,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Molecular Mechanisms of Cancer",3.99,0.0775,"NaN","CHEK2","checkpoint kinase 2","Nucleus","kinase",0.0028598784,0.0017272087,"up",1.3150214,1.3150214,0.39508626]
["Molecular Mechanisms of Cancer",3.99,0.0775,"NaN","ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["Molecular Mechanisms of Cancer",3.99,0.0775,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Molecular Mechanisms of Cancer",3.99,0.0775,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Molecular Mechanisms of Cancer",3.99,0.0775,"NaN","RALB","v-ral simian leukemia viral oncogene homolog B","Cytoplasm","enzyme",0.0022762846,0.0012371538,"up",1.7571107,1.7571107,0.81320506]
["Molecular Mechanisms of Cancer",3.99,0.0775,"NaN","CDK6","cyclin-dependent kinase 6","Nucleus","kinase",0.0011555209,0.0002428485,"down",1.6726129,-1.6726129,-0.7421036]
["Molecular Mechanisms of Cancer",3.99,0.0775,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Molecular Mechanisms of Cancer",3.99,0.0775,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Molecular Mechanisms of Cancer",3.99,0.0775,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Molecular Mechanisms of Cancer",3.99,0.0775,"NaN","CDH1","cadherin 1","Plasma Membrane","other",0.0017019173,0.0006999703,"up",1.452055,1.452055,0.5380961]
["Molecular Mechanisms of Cancer",3.99,0.0775,"NaN","CCNE1","cyclin E1","Nucleus","transcription regulator",0.0013342145,0.00036659295,"down",2.6488216,-2.6488216,-1.4053507]
["Molecular Mechanisms of Cancer",3.99,0.0775,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Molecular Mechanisms of Cancer",3.99,0.0775,"NaN","CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["Molecular Mechanisms of Cancer",3.99,0.0775,"NaN","CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["Molecular Mechanisms of Cancer",3.99,0.0775,"NaN","PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Molecular Mechanisms of Cancer",3.99,0.0775,"NaN","APH1B","aph-1 homolog B, gamma secretase subunit","Other","peptidase",0.0012306612,0.00029680028,"up",1.5021218,1.5021218,0.5870018]
["Molecular Mechanisms of Cancer",3.99,0.0775,"NaN","FZD5","frizzled class receptor 5","Plasma Membrane","G-protein coupled receptor",0.0011555209,0.00024123449,"down",1.5153433,-1.5153433,-0.59964466]
["Molecular Mechanisms of Cancer",3.99,0.0775,"NaN","BMP6","bone morphogenetic protein 6","Extracellular Space","growth factor",0.0012361597,0.00030026503,"up",1.359715,1.359715,0.44330427]
["Role of Tissue Factor in Cancer",3.88,0.115,"NaN","ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["Role of Tissue Factor in Cancer",3.88,0.115,"NaN","CXCL8","C-X-C motif chemokine ligand 8","Extracellular Space","cytokine",0.0011259156,0.00022286079,"down",1.5851029,-1.5851029,-0.66457653]
["Role of Tissue Factor in Cancer",3.88,0.115,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Role of Tissue Factor in Cancer",3.88,0.115,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Role of Tissue Factor in Cancer",3.88,0.115,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Role of Tissue Factor in Cancer",3.88,0.115,"NaN","PLAUR","plasminogen activator, urokinase receptor","Plasma Membrane","transmembrane receptor",0.0010741793,0.00018365598,"down",1.485067,-1.485067,-0.57052803]
["Role of Tissue Factor in Cancer",3.88,0.115,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Role of Tissue Factor in Cancer",3.88,0.115,"NaN","LIMK2","LIM domain kinase 2","Cytoplasm","kinase",0.0035328772,0.002318736,"up",1.3875531,1.3875531,0.47254297]
["Role of Tissue Factor in Cancer",3.88,0.115,"NaN","PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["Role of Tissue Factor in Cancer",3.88,0.115,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Role of Tissue Factor in Cancer",3.88,0.115,"NaN","ARRB1","arrestin beta 1","Cytoplasm","other",0.0032341068,0.0020446463,"up",1.4974334,1.4974334,0.5824919]
["Role of Tissue Factor in Cancer",3.88,0.115,"NaN","CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["Role of Tissue Factor in Cancer",3.88,0.115,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Role of Tissue Factor in Cancer",3.88,0.115,"NaN","CYR61","cysteine rich angiogenic inducer 61","Extracellular Space","other",0.0014103054,0.00042576404,"up",1.6788704,1.6788704,0.7474909]
["AMPK Signaling",3.75,0.0952,1,"PBRM1","polybromo 1","Nucleus","other",0.0055692703,0.0042261216,"down",1.4428215,-1.4428215,-0.5288928]
["AMPK Signaling",3.75,0.0952,1,"TSC1","tuberous sclerosis 1","Cytoplasm","other",0.0020370672,0.0010299383,"up",1.3084451,1.3084451,0.38785338]
["AMPK Signaling",3.75,0.0952,1,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["AMPK Signaling",3.75,0.0952,1,"SLC2A1","solute carrier family 2 member 1","Plasma Membrane","transporter",0.0010998568,0.00021028184,"down",1.3829497,-1.3829497,-0.4677487]
["AMPK Signaling",3.75,0.0952,1,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["AMPK Signaling",3.75,0.0952,1,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["AMPK Signaling",3.75,0.0952,1,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["AMPK Signaling",3.75,0.0952,1,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["AMPK Signaling",3.75,0.0952,1,"PPM1D","protein phosphatase, Mg2+/Mn2+ dependent 1D","Cytoplasm","phosphatase",0.0017398865,0.0007406382,"down",1.7109653,-1.7109653,-0.7748105]
["AMPK Signaling",3.75,0.0952,1,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["AMPK Signaling",3.75,0.0952,1,"CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["AMPK Signaling",3.75,0.0952,1,"PRKAA2","protein kinase AMP-activated catalytic subunit alpha 2","Cytoplasm","kinase",0.0014867174,0.0005054725,"up",1.3466656,1.3466656,0.42939165]
["AMPK Signaling",3.75,0.0952,1,"PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["AMPK Signaling",3.75,0.0952,1,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["AMPK Signaling",3.75,0.0952,1,"CPT1C","carnitine palmitoyltransferase 1C","Cytoplasm","enzyme",0.004112417,0.0028478752,"up",1.3991864,1.3991864,0.48458815]
["AMPK Signaling",3.75,0.0952,1,"EEF2K","eukaryotic elongation factor 2 kinase","Cytoplasm","kinase",0.0013760548,0.00039997842,"down",1.5132525,-1.5132525,-0.59765273]
["AMPK Signaling",3.75,0.0952,1,"HNF4A","hepatocyte nuclear factor 4 alpha","Nucleus","transcription regulator",0.0018693322,0.0008653767,"up",1.4698008,1.4698008,0.5556207]
["AMPK Signaling",3.75,0.0952,1,"HMGCR","3-hydroxy-3-methylglutaryl-CoA reductase","Cytoplasm","enzyme",0.0014677041,0.00048228173,"up",1.3671681,1.3671681,0.4511906]
["Small Cell Lung Cancer Signaling",3.67,0.131,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Small Cell Lung Cancer Signaling",3.67,0.131,"NaN","IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["Small Cell Lung Cancer Signaling",3.67,0.131,"NaN","CCNE1","cyclin E1","Nucleus","transcription regulator",0.0013342145,0.00036659295,"down",2.6488216,-2.6488216,-1.4053507]
["Small Cell Lung Cancer Signaling",3.67,0.131,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Small Cell Lung Cancer Signaling",3.67,0.131,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Small Cell Lung Cancer Signaling",3.67,0.131,"NaN","CDK6","cyclin-dependent kinase 6","Nucleus","kinase",0.0011555209,0.0002428485,"down",1.6726129,-1.6726129,-0.7421036]
["Small Cell Lung Cancer Signaling",3.67,0.131,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Small Cell Lung Cancer Signaling",3.67,0.131,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Small Cell Lung Cancer Signaling",3.67,0.131,"NaN","PTGS2","prostaglandin-endoperoxide synthase 2","Cytoplasm","enzyme",0.0012584343,0.00031259237,"down",1.4767396,-1.4767396,-0.5624155]
["Small Cell Lung Cancer Signaling",3.67,0.131,"NaN","SKP2","S-phase kinase-associated protein 2, E3 ubiquitin protein ligase","Nucleus","enzyme",0.0014867174,0.000499228,"up",1.348095,1.348095,0.4309222]
["Small Cell Lung Cancer Signaling",3.67,0.131,"NaN","PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["IL-17 Signaling",3.63,0.129,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["IL-17 Signaling",3.63,0.129,"NaN","CXCL8","C-X-C motif chemokine ligand 8","Extracellular Space","cytokine",0.0011259156,0.00022286079,"down",1.5851029,-1.5851029,-0.66457653]
["IL-17 Signaling",3.63,0.129,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["IL-17 Signaling",3.63,0.129,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["IL-17 Signaling",3.63,0.129,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["IL-17 Signaling",3.63,0.129,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["IL-17 Signaling",3.63,0.129,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["IL-17 Signaling",3.63,0.129,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["IL-17 Signaling",3.63,0.129,"NaN","CEBPB","CCAAT/enhancer binding protein beta","Nucleus","transcription regulator",0.021593252,0.020254135,"down",1.3026826,-1.3026826,-0.38148564]
["IL-17 Signaling",3.63,0.129,"NaN","PTGS2","prostaglandin-endoperoxide synthase 2","Cytoplasm","enzyme",0.0012584343,0.00031259237,"down",1.4767396,-1.4767396,-0.5624155]
["IL-17 Signaling",3.63,0.129,"NaN","ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["Signaling by Rho Family GTPases",3.58,0.085,2.065,"GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["Signaling by Rho Family GTPases",3.58,0.085,2.065,"ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["Signaling by Rho Family GTPases",3.58,0.085,2.065,"SEPT8","septin 8","Extracellular Space","other",0.0012172924,0.0002738324,"up",1.4083673,1.4083673,0.4940236]
["Signaling by Rho Family GTPases",3.58,0.085,2.065,"NEDD4","neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase","Cytoplasm","enzyme",0.00067191356,4.1885378e-05,"up",2.6203134,2.6203134,1.3897394]
["Signaling by Rho Family GTPases",3.58,0.085,2.065,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Signaling by Rho Family GTPases",3.58,0.085,2.065,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Signaling by Rho Family GTPases",3.58,0.085,2.065,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Signaling by Rho Family GTPases",3.58,0.085,2.065,"WASL","Wiskott-Aldrich syndrome like","Cytoplasm","other",0.00040977335,6.54692e-06,"up",1.4019742,1.4019742,0.4874598]
["Signaling by Rho Family GTPases",3.58,0.085,2.065,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Signaling by Rho Family GTPases",3.58,0.085,2.065,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Signaling by Rho Family GTPases",3.58,0.085,2.065,"MYL6B","myosin light chain 6B","Cytoplasm","other",0.0037700427,0.0025393397,"up",1.3426967,1.3426967,0.4251334]
["Signaling by Rho Family GTPases",3.58,0.085,2.065,"LIMK2","LIM domain kinase 2","Cytoplasm","kinase",0.0035328772,0.002318736,"up",1.3875531,1.3875531,0.47254297]
["Signaling by Rho Family GTPases",3.58,0.085,2.065,"ROCK2","Rho associated coiled-coil containing protein kinase 2","Cytoplasm","kinase",0.0010184328,0.00016622998,"up",1.3479002,1.3479002,0.43071362]
["Signaling by Rho Family GTPases",3.58,0.085,2.065,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Signaling by Rho Family GTPases",3.58,0.085,2.065,"CDH1","cadherin 1","Plasma Membrane","other",0.0017019173,0.0006999703,"up",1.452055,1.452055,0.5380961]
["Signaling by Rho Family GTPases",3.58,0.085,2.065,"CDH2","cadherin 2","Plasma Membrane","other",0.001091852,0.00020167766,"up",1.3591936,1.3591936,0.44275093]
["Signaling by Rho Family GTPases",3.58,0.085,2.065,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Signaling by Rho Family GTPases",3.58,0.085,2.065,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["Signaling by Rho Family GTPases",3.58,0.085,2.065,"RHOU","ras homolog family member U","Cytoplasm","enzyme",0.0009194498,0.00012193339,"down",1.7715495,-1.7715495,-0.82501173]
["Signaling by Rho Family GTPases",3.58,0.085,2.065,"SEPT6","septin 6","Cytoplasm","other",0.00077926775,7.637247e-05,"up",1.5135813,1.5135813,0.59796613]
["Signaling by Rho Family GTPases",3.58,0.085,2.065,"SEPT2","septin 2","Cytoplasm","enzyme",0.0015251196,0.0005359594,"up",1.938313,1.938313,0.95480156]
["LPS-stimulated MAPK Signaling",3.58,0.128,0.302,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["LPS-stimulated MAPK Signaling",3.58,0.128,0.302,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["LPS-stimulated MAPK Signaling",3.58,0.128,0.302,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["LPS-stimulated MAPK Signaling",3.58,0.128,0.302,"ATF1","activating transcription factor 1","Nucleus","transcription regulator",0.0070709703,0.005685401,"down",1.3784643,-1.3784643,-0.46306193]
["LPS-stimulated MAPK Signaling",3.58,0.128,0.302,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["LPS-stimulated MAPK Signaling",3.58,0.128,0.302,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["LPS-stimulated MAPK Signaling",3.58,0.128,0.302,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["LPS-stimulated MAPK Signaling",3.58,0.128,0.302,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["LPS-stimulated MAPK Signaling",3.58,0.128,0.302,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["LPS-stimulated MAPK Signaling",3.58,0.128,0.302,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["LPS-stimulated MAPK Signaling",3.58,0.128,0.302,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["Epithelial Adherens Junction Signaling",3.58,0.103,"NaN","TUBB3","tubulin beta 3 class III","Cytoplasm","other",0.001459056,0.00047059942,"up",1.4351482,1.4351482,0.52119976]
["Epithelial Adherens Junction Signaling",3.58,0.103,"NaN","TGFBR1","transforming growth factor beta receptor 1","Plasma Membrane","kinase",0.0008942897,0.00011058827,"up",1.5758384,1.5758384,0.65611964]
["Epithelial Adherens Junction Signaling",3.58,0.103,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Epithelial Adherens Junction Signaling",3.58,0.103,"NaN","WASL","Wiskott-Aldrich syndrome like","Cytoplasm","other",0.00040977335,6.54692e-06,"up",1.4019742,1.4019742,0.4874598]
["Epithelial Adherens Junction Signaling",3.58,0.103,"NaN","TUBB2A","tubulin beta 2A class IIa","Cytoplasm","other",0.0026605518,0.0015617278,"up",1.4475315,1.4475315,0.5335947]
["Epithelial Adherens Junction Signaling",3.58,0.103,"NaN","MLLT4","myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4","Nucleus","other",0.0013056329,0.00034460775,"up",1.7435131,1.7435131,0.8019972]
["Epithelial Adherens Junction Signaling",3.58,0.103,"NaN","MYL6B","myosin light chain 6B","Cytoplasm","other",0.0037700427,0.0025393397,"up",1.3426967,1.3426967,0.4251334]
["Epithelial Adherens Junction Signaling",3.58,0.103,"NaN","PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["Epithelial Adherens Junction Signaling",3.58,0.103,"NaN","MET","MET proto-oncogene, receptor tyrosine kinase","Plasma Membrane","kinase",0.0008691947,0.00010051858,"up",1.5833938,1.5833938,0.66302013]
["Epithelial Adherens Junction Signaling",3.58,0.103,"NaN","CDH2","cadherin 2","Plasma Membrane","other",0.001091852,0.00020167766,"up",1.3591936,1.3591936,0.44275093]
["Epithelial Adherens Junction Signaling",3.58,0.103,"NaN","CDH1","cadherin 1","Plasma Membrane","other",0.0017019173,0.0006999703,"up",1.452055,1.452055,0.5380961]
["Epithelial Adherens Junction Signaling",3.58,0.103,"NaN","CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["Epithelial Adherens Junction Signaling",3.58,0.103,"NaN","SSX2IP","synovial sarcoma, X breakpoint 2 interacting protein","Plasma Membrane","other",0.0013953822,0.00041306,"down",1.3860103,-1.3860103,-0.47093797]
["Epithelial Adherens Junction Signaling",3.58,0.103,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Epithelial Adherens Junction Signaling",3.58,0.103,"NaN","NECTIN2","nectin cell adhesion molecule 2","Plasma Membrane","transmembrane receptor",0.0023623689,0.0013073402,"up",1.3960435,1.3960435,0.48134392]
["Glucocorticoid Receptor Signaling",3.49,0.0801,"NaN","PBRM1","polybromo 1","Nucleus","other",0.0055692703,0.0042261216,"down",1.4428215,-1.4428215,-0.5288928]
["Glucocorticoid Receptor Signaling",3.49,0.0801,"NaN","CXCL8","C-X-C motif chemokine ligand 8","Extracellular Space","cytokine",0.0011259156,0.00022286079,"down",1.5851029,-1.5851029,-0.66457653]
["Glucocorticoid Receptor Signaling",3.49,0.0801,"NaN","TGFBR1","transforming growth factor beta receptor 1","Plasma Membrane","kinase",0.0008942897,0.00011058827,"up",1.5758384,1.5758384,0.65611964]
["Glucocorticoid Receptor Signaling",3.49,0.0801,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Glucocorticoid Receptor Signaling",3.49,0.0801,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Glucocorticoid Receptor Signaling",3.49,0.0801,"NaN","MED1","mediator complex subunit 1","Nucleus","transcription regulator",0.007830824,0.006407651,"down",1.3726159,-1.3726159,-0.456928]
["Glucocorticoid Receptor Signaling",3.49,0.0801,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Glucocorticoid Receptor Signaling",3.49,0.0801,"NaN","PBX1","pre-B-cell leukemia homeobox 1","Nucleus","transcription regulator",0.008041076,0.006617785,"up",1.410497,1.410497,0.49620354]
["Glucocorticoid Receptor Signaling",3.49,0.0801,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Glucocorticoid Receptor Signaling",3.49,0.0801,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Glucocorticoid Receptor Signaling",3.49,0.0801,"NaN","CEBPB","CCAAT/enhancer binding protein beta","Nucleus","transcription regulator",0.021593252,0.020254135,"down",1.3026826,-1.3026826,-0.38148564]
["Glucocorticoid Receptor Signaling",3.49,0.0801,"NaN","HSPA5","heat shock protein family A (Hsp70) member 5","Cytoplasm","enzyme",0.007907775,0.006494456,"down",1.3693051,-1.3693051,-0.45344397]
["Glucocorticoid Receptor Signaling",3.49,0.0801,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Glucocorticoid Receptor Signaling",3.49,0.0801,"NaN","IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["Glucocorticoid Receptor Signaling",3.49,0.0801,"NaN","TAF1","TATA-box binding protein associated factor 1","Nucleus","transcription regulator",0.00084399927,9.268726e-05,"down",1.4030962,-1.4030962,-0.48861393]
["Glucocorticoid Receptor Signaling",3.49,0.0801,"NaN","CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["Glucocorticoid Receptor Signaling",3.49,0.0801,"NaN","PRKAA2","protein kinase AMP-activated catalytic subunit alpha 2","Cytoplasm","kinase",0.0014867174,0.0005054725,"up",1.3466656,1.3466656,0.42939165]
["Glucocorticoid Receptor Signaling",3.49,0.0801,"NaN","PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Glucocorticoid Receptor Signaling",3.49,0.0801,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Glucocorticoid Receptor Signaling",3.49,0.0801,"NaN","HSP90AA1","heat shock protein 90kDa alpha family class A member 1","Cytoplasm","enzyme",0.0005783946,2.0937947e-05,"up",1.5556576,1.5556576,0.63752455]
["Glucocorticoid Receptor Signaling",3.49,0.0801,"NaN","PTGS2","prostaglandin-endoperoxide synthase 2","Cytoplasm","enzyme",0.0012584343,0.00031259237,"down",1.4767396,-1.4767396,-0.5624155]
["Glucocorticoid Receptor Signaling",3.49,0.0801,"NaN","SERPINE1","serpin family E member 1","Extracellular Space","other",0.0016010772,0.00060374127,"up",1.3806411,1.3806411,0.46533832]
["Glucocorticoid Receptor Signaling",3.49,0.0801,"NaN","CREBZF","CREB/ATF bZIP transcription factor","Nucleus","transcription regulator",0.0012460877,0.00030734768,"down",1.6405082,-1.6405082,-0.7141428]
["Pancreatic Adenocarcinoma Signaling",3.47,0.11,0.905,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Pancreatic Adenocarcinoma Signaling",3.47,0.11,0.905,"CCNE1","cyclin E1","Nucleus","transcription regulator",0.0013342145,0.00036659295,"down",2.6488216,-2.6488216,-1.4053507]
["Pancreatic Adenocarcinoma Signaling",3.47,0.11,0.905,"TGFBR1","transforming growth factor beta receptor 1","Plasma Membrane","kinase",0.0008942897,0.00011058827,"up",1.5758384,1.5758384,0.65611964]
["Pancreatic Adenocarcinoma Signaling",3.47,0.11,0.905,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Pancreatic Adenocarcinoma Signaling",3.47,0.11,0.905,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["Pancreatic Adenocarcinoma Signaling",3.47,0.11,0.905,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Pancreatic Adenocarcinoma Signaling",3.47,0.11,0.905,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Pancreatic Adenocarcinoma Signaling",3.47,0.11,0.905,"CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["Pancreatic Adenocarcinoma Signaling",3.47,0.11,0.905,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Pancreatic Adenocarcinoma Signaling",3.47,0.11,0.905,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Pancreatic Adenocarcinoma Signaling",3.47,0.11,0.905,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Pancreatic Adenocarcinoma Signaling",3.47,0.11,0.905,"PTGS2","prostaglandin-endoperoxide synthase 2","Cytoplasm","enzyme",0.0012584343,0.00031259237,"down",1.4767396,-1.4767396,-0.5624155]
["Pancreatic Adenocarcinoma Signaling",3.47,0.11,0.905,"BIRC5","baculoviral IAP repeat containing 5","Cytoplasm","other",0.0018505693,0.00084797834,"up",1.5707992,1.5707992,0.6514988]
["Aldosterone Signaling in Epithelial Cells",3.46,0.0964,0.632,"NEDD4","neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase","Cytoplasm","enzyme",0.00067191356,4.1885378e-05,"up",2.6203134,2.6203134,1.3897394]
["Aldosterone Signaling in Epithelial Cells",3.46,0.0964,0.632,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Aldosterone Signaling in Epithelial Cells",3.46,0.0964,0.632,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Aldosterone Signaling in Epithelial Cells",3.46,0.0964,0.632,"SLC12A2","solute carrier family 12 member 2","Plasma Membrane","transporter",0.0040863724,0.0028245598,"up",1.3745189,1.3745189,0.4589267]
["Aldosterone Signaling in Epithelial Cells",3.46,0.0964,0.632,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Aldosterone Signaling in Epithelial Cells",3.46,0.0964,0.632,"DNAJC6","DnaJ heat shock protein family (Hsp40) member C6","Cytoplasm","other",0.00471877,0.0034019037,"up",1.5755986,1.5755986,0.6559]
["Aldosterone Signaling in Epithelial Cells",3.46,0.0964,0.632,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Aldosterone Signaling in Epithelial Cells",3.46,0.0964,0.632,"ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["Aldosterone Signaling in Epithelial Cells",3.46,0.0964,0.632,"HSPA5","heat shock protein family A (Hsp70) member 5","Cytoplasm","enzyme",0.007907775,0.006494456,"down",1.3693051,-1.3693051,-0.45344397]
["Aldosterone Signaling in Epithelial Cells",3.46,0.0964,0.632,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Aldosterone Signaling in Epithelial Cells",3.46,0.0964,0.632,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Aldosterone Signaling in Epithelial Cells",3.46,0.0964,0.632,"ASIC1","acid sensing ion channel subunit 1","Plasma Membrane","ion channel",0.005377771,0.0040252223,"up",1.512104,1.512104,0.5965574]
["Aldosterone Signaling in Epithelial Cells",3.46,0.0964,0.632,"DNAJC18","DnaJ heat shock protein family (Hsp40) member C18","Other","enzyme",0.004395149,0.0030934683,"up",1.7337146,1.7337146,0.7938664]
["Aldosterone Signaling in Epithelial Cells",3.46,0.0964,0.632,"HSP90AA1","heat shock protein 90kDa alpha family class A member 1","Cytoplasm","enzyme",0.0005783946,2.0937947e-05,"up",1.5556576,1.5556576,0.63752455]
["Aldosterone Signaling in Epithelial Cells",3.46,0.0964,0.632,"DNAJB6","DnaJ heat shock protein family (Hsp40) member B6","Nucleus","transcription regulator",0.0016760693,0.00068303355,"up",2.0961676,2.0961676,1.067754]
["Aldosterone Signaling in Epithelial Cells",3.46,0.0964,0.632,"DNAJB1","DnaJ heat shock protein family (Hsp40) member B1","Nucleus","other",0.0012010665,0.0002643174,"down",2.432129,-2.432129,-1.2822196]
["Mouse Embryonic Stem Cell Pluripotency",3.35,0.113,0,"SOX2","SRY-box 2","Nucleus","transcription regulator",0.0013107243,0.00034832067,"up",1.4385506,1.4385506,0.52461594]
["Mouse Embryonic Stem Cell Pluripotency",3.35,0.113,0,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Mouse Embryonic Stem Cell Pluripotency",3.35,0.113,0,"LIFR","leukemia inhibitory factor receptor alpha","Plasma Membrane","transmembrane receptor",0.001213793,0.00026979306,"up",1.903933,1.903933,0.92898273]
["Mouse Embryonic Stem Cell Pluripotency",3.35,0.113,0,"FZD10","frizzled class receptor 10","Plasma Membrane","G-protein coupled receptor",0.00084399927,9.184798e-05,"down",1.4670624,-1.4670624,-0.5529302]
["Mouse Embryonic Stem Cell Pluripotency",3.35,0.113,0,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Mouse Embryonic Stem Cell Pluripotency",3.35,0.113,0,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Mouse Embryonic Stem Cell Pluripotency",3.35,0.113,0,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Mouse Embryonic Stem Cell Pluripotency",3.35,0.113,0,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Mouse Embryonic Stem Cell Pluripotency",3.35,0.113,0,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Mouse Embryonic Stem Cell Pluripotency",3.35,0.113,0,"FZD5","frizzled class receptor 5","Plasma Membrane","G-protein coupled receptor",0.0011555209,0.00024123449,"down",1.5153433,-1.5153433,-0.59964466]
["Mouse Embryonic Stem Cell Pluripotency",3.35,0.113,0,"FZD1","frizzled class receptor 1","Plasma Membrane","G-protein coupled receptor",0.0036817046,0.002460812,"down",1.529664,-1.529664,-0.6132148]
["Mouse Embryonic Stem Cell Pluripotency",3.35,0.113,0,"SMAD5","SMAD family member 5","Nucleus","transcription regulator",0.0014749195,0.00048909907,"down",1.3112969,-1.3112969,-0.3909944]
["Pyridoxal 5'-phosphate Salvage Pathway",3.34,0.141,"NaN","PDXK","pyridoxal (pyridoxine, vitamin B6) kinase","Cytoplasm","kinase",0.0009735221,0.00014322254,"up",1.3547724,1.3547724,0.43805054]
["Pyridoxal 5'-phosphate Salvage Pathway",3.34,0.141,"NaN","PRKX","protein kinase, X-linked","Cytoplasm","kinase",0.00055139343,1.662609e-05,"down",1.4422405,-1.4422405,-0.5283117]
["Pyridoxal 5'-phosphate Salvage Pathway",3.34,0.141,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Pyridoxal 5'-phosphate Salvage Pathway",3.34,0.141,"NaN","PRPF4B","pre-mRNA processing factor 4B","Nucleus","kinase",0.012723735,0.0113428645,"down",1.3757049,-1.3757049,-0.460171]
["Pyridoxal 5'-phosphate Salvage Pathway",3.34,0.141,"NaN","PRKAA2","protein kinase AMP-activated catalytic subunit alpha 2","Cytoplasm","kinase",0.0014867174,0.0005054725,"up",1.3466656,1.3466656,0.42939165]
["Pyridoxal 5'-phosphate Salvage Pathway",3.34,0.141,"NaN","CDK6","cyclin-dependent kinase 6","Nucleus","kinase",0.0011555209,0.0002428485,"down",1.6726129,-1.6726129,-0.7421036]
["Pyridoxal 5'-phosphate Salvage Pathway",3.34,0.141,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Pyridoxal 5'-phosphate Salvage Pathway",3.34,0.141,"NaN","LIMK2","LIM domain kinase 2","Cytoplasm","kinase",0.0035328772,0.002318736,"up",1.3875531,1.3875531,0.47254297]
["Pyridoxal 5'-phosphate Salvage Pathway",3.34,0.141,"NaN","HIPK1","homeodomain interacting protein kinase 1","Nucleus","kinase",0.01500758,0.013656768,"down",1.3206239,-1.3206239,-0.40121964]
["Role of NANOG in Mammalian Embryonic Stem Cell Pluripotency",3.33,0.107,1.633,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Role of NANOG in Mammalian Embryonic Stem Cell Pluripotency",3.33,0.107,1.633,"SOX2","SRY-box 2","Nucleus","transcription regulator",0.0013107243,0.00034832067,"up",1.4385506,1.4385506,0.52461594]
["Role of NANOG in Mammalian Embryonic Stem Cell Pluripotency",3.33,0.107,1.633,"LIFR","leukemia inhibitory factor receptor alpha","Plasma Membrane","transmembrane receptor",0.001213793,0.00026979306,"up",1.903933,1.903933,0.92898273]
["Role of NANOG in Mammalian Embryonic Stem Cell Pluripotency",3.33,0.107,1.633,"FZD10","frizzled class receptor 10","Plasma Membrane","G-protein coupled receptor",0.00084399927,9.184798e-05,"down",1.4670624,-1.4670624,-0.5529302]
["Role of NANOG in Mammalian Embryonic Stem Cell Pluripotency",3.33,0.107,1.633,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Role of NANOG in Mammalian Embryonic Stem Cell Pluripotency",3.33,0.107,1.633,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Role of NANOG in Mammalian Embryonic Stem Cell Pluripotency",3.33,0.107,1.633,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Role of NANOG in Mammalian Embryonic Stem Cell Pluripotency",3.33,0.107,1.633,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Role of NANOG in Mammalian Embryonic Stem Cell Pluripotency",3.33,0.107,1.633,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Role of NANOG in Mammalian Embryonic Stem Cell Pluripotency",3.33,0.107,1.633,"FZD5","frizzled class receptor 5","Plasma Membrane","G-protein coupled receptor",0.0011555209,0.00024123449,"down",1.5153433,-1.5153433,-0.59964466]
["Role of NANOG in Mammalian Embryonic Stem Cell Pluripotency",3.33,0.107,1.633,"SMAD5","SMAD family member 5","Nucleus","transcription regulator",0.0014749195,0.00048909907,"down",1.3112969,-1.3112969,-0.3909944]
["Role of NANOG in Mammalian Embryonic Stem Cell Pluripotency",3.33,0.107,1.633,"FZD1","frizzled class receptor 1","Plasma Membrane","G-protein coupled receptor",0.0036817046,0.002460812,"down",1.529664,-1.529664,-0.6132148]
["Role of NANOG in Mammalian Embryonic Stem Cell Pluripotency",3.33,0.107,1.633,"BMP6","bone morphogenetic protein 6","Extracellular Space","growth factor",0.0012361597,0.00030026503,"up",1.359715,1.359715,0.44330427]
["Huntington's Disease Signaling",3.3,0.083,"NaN","GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["Huntington's Disease Signaling",3.3,0.083,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Huntington's Disease Signaling",3.3,0.083,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Huntington's Disease Signaling",3.3,0.083,"NaN","GLS","glutaminase","Cytoplasm","enzyme",0.0045107757,0.0032061748,"up",1.6075542,1.6075542,0.6848674]
["Huntington's Disease Signaling",3.3,0.083,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Huntington's Disease Signaling",3.3,0.083,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Huntington's Disease Signaling",3.3,0.083,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Huntington's Disease Signaling",3.3,0.083,"NaN","ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["Huntington's Disease Signaling",3.3,0.083,"NaN","HSPA5","heat shock protein family A (Hsp70) member 5","Cytoplasm","enzyme",0.007907775,0.006494456,"down",1.3693051,-1.3693051,-0.45344397]
["Huntington's Disease Signaling",3.3,0.083,"NaN","SNAP25","synaptosome associated protein 25kDa","Plasma Membrane","transporter",0.001213793,0.00027191787,"up",2.3686213,2.3686213,1.2440475]
["Huntington's Disease Signaling",3.3,0.083,"NaN","ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["Huntington's Disease Signaling",3.3,0.083,"NaN","HDAC6","histone deacetylase 6","Nucleus","transcription regulator",0.0060592825,0.0047327504,"up",1.6543902,1.6543902,0.7262995]
["Huntington's Disease Signaling",3.3,0.083,"NaN","TGM2","transglutaminase 2","Cytoplasm","enzyme",0.0012591777,0.00031366711,"down",1.4611537,-1.4611537,-0.547108]
["Huntington's Disease Signaling",3.3,0.083,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Huntington's Disease Signaling",3.3,0.083,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Huntington's Disease Signaling",3.3,0.083,"NaN","CASP2","caspase 2","Cytoplasm","peptidase",0.0015242294,0.0005334935,"down",1.3856739,-1.3856739,-0.47058776]
["Huntington's Disease Signaling",3.3,0.083,"NaN","CASP1","caspase 1","Cytoplasm","peptidase",0.0010976536,0.00020770791,"down",1.8456633,-1.8456633,-0.88413936]
["Huntington's Disease Signaling",3.3,0.083,"NaN","IGF1R","insulin like growth factor 1 receptor","Plasma Membrane","transmembrane receptor",0.0016147236,0.0006161828,"up",1.8701973,1.8701973,0.90319043]
["Huntington's Disease Signaling",3.3,0.083,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Huntington's Disease Signaling",3.3,0.083,"NaN","DNAJB1","DnaJ heat shock protein family (Hsp40) member B1","Nucleus","other",0.0012010665,0.0002643174,"down",2.432129,-2.432129,-1.2822196]
["Regulation of the Epithelial-Mesenchymal Transition Pathway",3.29,0.0899,"NaN","FZD10","frizzled class receptor 10","Plasma Membrane","G-protein coupled receptor",0.00084399927,9.184798e-05,"down",1.4670624,-1.4670624,-0.5529302]
["Regulation of the Epithelial-Mesenchymal Transition Pathway",3.29,0.0899,"NaN","LOX","lysyl oxidase","Extracellular Space","enzyme",0.0026042238,0.0015117389,"up",1.4011031,1.4011031,0.48656315]
["Regulation of the Epithelial-Mesenchymal Transition Pathway",3.29,0.0899,"NaN","TGFBR1","transforming growth factor beta receptor 1","Plasma Membrane","kinase",0.0008942897,0.00011058827,"up",1.5758384,1.5758384,0.65611964]
["Regulation of the Epithelial-Mesenchymal Transition Pathway",3.29,0.0899,"NaN","PSENEN","presenilin enhancer gamma secretase subunit","Plasma Membrane","peptidase",0.0017462111,0.00074735825,"up",1.374307,1.374307,0.45870435]
["Regulation of the Epithelial-Mesenchymal Transition Pathway",3.29,0.0899,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Regulation of the Epithelial-Mesenchymal Transition Pathway",3.29,0.0899,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Regulation of the Epithelial-Mesenchymal Transition Pathway",3.29,0.0899,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Regulation of the Epithelial-Mesenchymal Transition Pathway",3.29,0.0899,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Regulation of the Epithelial-Mesenchymal Transition Pathway",3.29,0.0899,"NaN","FZD1","frizzled class receptor 1","Plasma Membrane","G-protein coupled receptor",0.0036817046,0.002460812,"down",1.529664,-1.529664,-0.6132148]
["Regulation of the Epithelial-Mesenchymal Transition Pathway",3.29,0.0899,"NaN","MET","MET proto-oncogene, receptor tyrosine kinase","Plasma Membrane","kinase",0.0008691947,0.00010051858,"up",1.5833938,1.5833938,0.66302013]
["Regulation of the Epithelial-Mesenchymal Transition Pathway",3.29,0.0899,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Regulation of the Epithelial-Mesenchymal Transition Pathway",3.29,0.0899,"NaN","CDH1","cadherin 1","Plasma Membrane","other",0.0017019173,0.0006999703,"up",1.452055,1.452055,0.5380961]
["Regulation of the Epithelial-Mesenchymal Transition Pathway",3.29,0.0899,"NaN","CDH2","cadherin 2","Plasma Membrane","other",0.001091852,0.00020167766,"up",1.3591936,1.3591936,0.44275093]
["Regulation of the Epithelial-Mesenchymal Transition Pathway",3.29,0.0899,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Regulation of the Epithelial-Mesenchymal Transition Pathway",3.29,0.0899,"NaN","APH1B","aph-1 homolog B, gamma secretase subunit","Other","peptidase",0.0012306612,0.00029680028,"up",1.5021218,1.5021218,0.5870018]
["Regulation of the Epithelial-Mesenchymal Transition Pathway",3.29,0.0899,"NaN","FZD5","frizzled class receptor 5","Plasma Membrane","G-protein coupled receptor",0.0011555209,0.00024123449,"down",1.5153433,-1.5153433,-0.59964466]
["Regulation of the Epithelial-Mesenchymal Transition Pathway",3.29,0.0899,"NaN","HMGA2","high mobility group AT-hook 2","Nucleus","enzyme",0.00031084043,2.0233713e-06,"up",2.3227482,2.3227482,1.2158327]
["PI3K/AKT Signaling",3.26,0.105,0.577,"ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["PI3K/AKT Signaling",3.26,0.105,0.577,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["PI3K/AKT Signaling",3.26,0.105,0.577,"TSC1","tuberous sclerosis 1","Cytoplasm","other",0.0020370672,0.0010299383,"up",1.3084451,1.3084451,0.38785338]
["PI3K/AKT Signaling",3.26,0.105,0.577,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["PI3K/AKT Signaling",3.26,0.105,0.577,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["PI3K/AKT Signaling",3.26,0.105,0.577,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["PI3K/AKT Signaling",3.26,0.105,0.577,"GDF15","growth differentiation factor 15","Extracellular Space","growth factor",0.0020635107,0.0010504175,"down",1.6351438,-1.6351438,-0.70941746]
["PI3K/AKT Signaling",3.26,0.105,0.577,"CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["PI3K/AKT Signaling",3.26,0.105,0.577,"RPS6KB2","ribosomal protein S6 kinase B2","Cytoplasm","kinase",0.0016431456,0.0006520507,"down",1.986918,-1.986918,-0.9905323]
["PI3K/AKT Signaling",3.26,0.105,0.577,"HSP90AA1","heat shock protein 90kDa alpha family class A member 1","Cytoplasm","enzyme",0.0005783946,2.0937947e-05,"up",1.5556576,1.5556576,0.63752455]
["PI3K/AKT Signaling",3.26,0.105,0.577,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["PI3K/AKT Signaling",3.26,0.105,0.577,"PTGS2","prostaglandin-endoperoxide synthase 2","Cytoplasm","enzyme",0.0012584343,0.00031259237,"down",1.4767396,-1.4767396,-0.5624155]
["PI3K/AKT Signaling",3.26,0.105,0.577,"PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["Prostate Cancer Signaling",3.24,0.117,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Prostate Cancer Signaling",3.24,0.117,"NaN","CCNE1","cyclin E1","Nucleus","transcription regulator",0.0013342145,0.00036659295,"down",2.6488216,-2.6488216,-1.4053507]
["Prostate Cancer Signaling",3.24,0.117,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Prostate Cancer Signaling",3.24,0.117,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Prostate Cancer Signaling",3.24,0.117,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Prostate Cancer Signaling",3.24,0.117,"NaN","CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["Prostate Cancer Signaling",3.24,0.117,"NaN","HSP90AA1","heat shock protein 90kDa alpha family class A member 1","Cytoplasm","enzyme",0.0005783946,2.0937947e-05,"up",1.5556576,1.5556576,0.63752455]
["Prostate Cancer Signaling",3.24,0.117,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Prostate Cancer Signaling",3.24,0.117,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Prostate Cancer Signaling",3.24,0.117,"NaN","PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["Prostate Cancer Signaling",3.24,0.117,"NaN","ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["Insulin Receptor Signaling",3.23,0.0993,0.535,"TSC1","tuberous sclerosis 1","Cytoplasm","other",0.0020370672,0.0010299383,"up",1.3084451,1.3084451,0.38785338]
["Insulin Receptor Signaling",3.23,0.0993,0.535,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Insulin Receptor Signaling",3.23,0.0993,0.535,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Insulin Receptor Signaling",3.23,0.0993,0.535,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Insulin Receptor Signaling",3.23,0.0993,0.535,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Insulin Receptor Signaling",3.23,0.0993,0.535,"PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["Insulin Receptor Signaling",3.23,0.0993,0.535,"GRB10","growth factor receptor bound protein 10","Cytoplasm","other",0.0012233602,0.00028852653,"up",1.7130156,1.7130156,0.77653825]
["Insulin Receptor Signaling",3.23,0.0993,0.535,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Insulin Receptor Signaling",3.23,0.0993,0.535,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Insulin Receptor Signaling",3.23,0.0993,0.535,"PDE3B","phosphodiesterase 3B","Cytoplasm","enzyme",0.0026252405,0.0015308249,"up",1.3255126,1.3255126,0.40655044]
["Insulin Receptor Signaling",3.23,0.0993,0.535,"RPS6KB2","ribosomal protein S6 kinase B2","Cytoplasm","kinase",0.0016431456,0.0006520507,"down",1.986918,-1.986918,-0.9905323]
["Insulin Receptor Signaling",3.23,0.0993,0.535,"PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Insulin Receptor Signaling",3.23,0.0993,0.535,"ASIC1","acid sensing ion channel subunit 1","Plasma Membrane","ion channel",0.005377771,0.0040252223,"up",1.512104,1.512104,0.5965574]
["Insulin Receptor Signaling",3.23,0.0993,0.535,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Role of NFAT in Cardiac Hypertrophy",3.21,0.0885,0.5,"GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["Role of NFAT in Cardiac Hypertrophy",3.21,0.0885,0.5,"TGFBR1","transforming growth factor beta receptor 1","Plasma Membrane","kinase",0.0008942897,0.00011058827,"up",1.5758384,1.5758384,0.65611964]
["Role of NFAT in Cardiac Hypertrophy",3.21,0.0885,0.5,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Role of NFAT in Cardiac Hypertrophy",3.21,0.0885,0.5,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Role of NFAT in Cardiac Hypertrophy",3.21,0.0885,0.5,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Role of NFAT in Cardiac Hypertrophy",3.21,0.0885,0.5,"MEF2A","myocyte enhancer factor 2A","Nucleus","transcription regulator",0.015937602,0.014585446,"down",1.3274704,-1.3274704,-0.40867972]
["Role of NFAT in Cardiac Hypertrophy",3.21,0.0885,0.5,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Role of NFAT in Cardiac Hypertrophy",3.21,0.0885,0.5,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Role of NFAT in Cardiac Hypertrophy",3.21,0.0885,0.5,"ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["Role of NFAT in Cardiac Hypertrophy",3.21,0.0885,0.5,"HDAC6","histone deacetylase 6","Nucleus","transcription regulator",0.0060592825,0.0047327504,"up",1.6543902,1.6543902,0.7262995]
["Role of NFAT in Cardiac Hypertrophy",3.21,0.0885,0.5,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Role of NFAT in Cardiac Hypertrophy",3.21,0.0885,0.5,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Role of NFAT in Cardiac Hypertrophy",3.21,0.0885,0.5,"MEF2D","myocyte enhancer factor 2D","Nucleus","transcription regulator",0.0006217929,3.203251e-05,"down",1.3555743,-1.3555743,-0.43890414]
["Role of NFAT in Cardiac Hypertrophy",3.21,0.0885,0.5,"IGF1R","insulin like growth factor 1 receptor","Plasma Membrane","transmembrane receptor",0.0016147236,0.0006161828,"up",1.8701973,1.8701973,0.90319043]
["Role of NFAT in Cardiac Hypertrophy",3.21,0.0885,0.5,"PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Role of NFAT in Cardiac Hypertrophy",3.21,0.0885,0.5,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Role of NFAT in Cardiac Hypertrophy",3.21,0.0885,0.5,"RCAN3","RCAN family member 3","Other","other",0.0008613762,9.7631746e-05,"up",1.423743,1.423743,0.50968874]
["Hereditary Breast Cancer Signaling",3.2,0.0986,"NaN","PBRM1","polybromo 1","Nucleus","other",0.0055692703,0.0042261216,"down",1.4428215,-1.4428215,-0.5288928]
["Hereditary Breast Cancer Signaling",3.2,0.0986,"NaN","GADD45B","growth arrest and DNA damage inducible beta","Cytoplasm","other",0.0013662435,0.00038785784,"up",1.6800824,1.6800824,0.748532]
["Hereditary Breast Cancer Signaling",3.2,0.0986,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Hereditary Breast Cancer Signaling",3.2,0.0986,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Hereditary Breast Cancer Signaling",3.2,0.0986,"NaN","CDK6","cyclin-dependent kinase 6","Nucleus","kinase",0.0011555209,0.0002428485,"down",1.6726129,-1.6726129,-0.7421036]
["Hereditary Breast Cancer Signaling",3.2,0.0986,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Hereditary Breast Cancer Signaling",3.2,0.0986,"NaN","RFC1","replication factor C subunit 1","Nucleus","transcription regulator",0.011040431,0.009618774,"up",1.3221459,1.3221459,0.4028814]
["Hereditary Breast Cancer Signaling",3.2,0.0986,"NaN","PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["Hereditary Breast Cancer Signaling",3.2,0.0986,"NaN","CHEK1","checkpoint kinase 1","Nucleus","kinase",0.0010877973,0.00019520131,"up",1.4226359,1.4226359,0.5085665]
["Hereditary Breast Cancer Signaling",3.2,0.0986,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Hereditary Breast Cancer Signaling",3.2,0.0986,"NaN","HDAC6","histone deacetylase 6","Nucleus","transcription regulator",0.0060592825,0.0047327504,"up",1.6543902,1.6543902,0.7262995]
["Hereditary Breast Cancer Signaling",3.2,0.0986,"NaN","CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["Hereditary Breast Cancer Signaling",3.2,0.0986,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Hereditary Breast Cancer Signaling",3.2,0.0986,"NaN","CHEK2","checkpoint kinase 2","Nucleus","kinase",0.0028598784,0.0017272087,"up",1.3150214,1.3150214,0.39508626]
["Role of IL-17A in Arthritis",3.19,0.134,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Role of IL-17A in Arthritis",3.19,0.134,"NaN","CXCL8","C-X-C motif chemokine ligand 8","Extracellular Space","cytokine",0.0011259156,0.00022286079,"down",1.5851029,-1.5851029,-0.66457653]
["Role of IL-17A in Arthritis",3.19,0.134,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Role of IL-17A in Arthritis",3.19,0.134,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Role of IL-17A in Arthritis",3.19,0.134,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Role of IL-17A in Arthritis",3.19,0.134,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Role of IL-17A in Arthritis",3.19,0.134,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Role of IL-17A in Arthritis",3.19,0.134,"NaN","PTGS2","prostaglandin-endoperoxide synthase 2","Cytoplasm","enzyme",0.0012584343,0.00031259237,"down",1.4767396,-1.4767396,-0.5624155]
["Role of IL-17A in Arthritis",3.19,0.134,"NaN","ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["Macropinocytosis Signaling",3.18,0.123,-0.378,"ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["Macropinocytosis Signaling",3.18,0.123,-0.378,"MET","MET proto-oncogene, receptor tyrosine kinase","Plasma Membrane","kinase",0.0008691947,0.00010051858,"up",1.5833938,1.5833938,0.66302013]
["Macropinocytosis Signaling",3.18,0.123,-0.378,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Macropinocytosis Signaling",3.18,0.123,-0.378,"RAB5A","RAB5A, member RAS oncogene family","Cytoplasm","enzyme",0.001415604,0.00043224083,"up",1.4926699,1.4926699,0.57789516]
["Macropinocytosis Signaling",3.18,0.123,-0.378,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Macropinocytosis Signaling",3.18,0.123,-0.378,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Macropinocytosis Signaling",3.18,0.123,-0.378,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["Macropinocytosis Signaling",3.18,0.123,-0.378,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Macropinocytosis Signaling",3.18,0.123,-0.378,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Macropinocytosis Signaling",3.18,0.123,-0.378,"ITGB8","integrin subunit beta 8","Plasma Membrane","other",0.0039384346,0.0026866843,"up",1.8310404,1.8310404,0.8726636]
["Ovarian Cancer Signaling",3.13,0.0972,"NaN","FZD10","frizzled class receptor 10","Plasma Membrane","G-protein coupled receptor",0.00084399927,9.184798e-05,"down",1.4670624,-1.4670624,-0.5529302]
["Ovarian Cancer Signaling",3.13,0.0972,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Ovarian Cancer Signaling",3.13,0.0972,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Ovarian Cancer Signaling",3.13,0.0972,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Ovarian Cancer Signaling",3.13,0.0972,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Ovarian Cancer Signaling",3.13,0.0972,"NaN","FZD1","frizzled class receptor 1","Plasma Membrane","G-protein coupled receptor",0.0036817046,0.002460812,"down",1.529664,-1.529664,-0.6132148]
["Ovarian Cancer Signaling",3.13,0.0972,"NaN","PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["Ovarian Cancer Signaling",3.13,0.0972,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Ovarian Cancer Signaling",3.13,0.0972,"NaN","ARRB1","arrestin beta 1","Cytoplasm","other",0.0032341068,0.0020446463,"up",1.4974334,1.4974334,0.5824919]
["Ovarian Cancer Signaling",3.13,0.0972,"NaN","PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Ovarian Cancer Signaling",3.13,0.0972,"NaN","RPS6KB2","ribosomal protein S6 kinase B2","Cytoplasm","kinase",0.0016431456,0.0006520507,"down",1.986918,-1.986918,-0.9905323]
["Ovarian Cancer Signaling",3.13,0.0972,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Ovarian Cancer Signaling",3.13,0.0972,"NaN","FZD5","frizzled class receptor 5","Plasma Membrane","G-protein coupled receptor",0.0011555209,0.00024123449,"down",1.5153433,-1.5153433,-0.59964466]
["Ovarian Cancer Signaling",3.13,0.0972,"NaN","PTGS2","prostaglandin-endoperoxide synthase 2","Cytoplasm","enzyme",0.0012584343,0.00031259237,"down",1.4767396,-1.4767396,-0.5624155]
["Inflammasome pathway",3.12,0.238,-1,"CXCL8","C-X-C motif chemokine ligand 8","Extracellular Space","cytokine",0.0011259156,0.00022286079,"down",1.5851029,-1.5851029,-0.66457653]
["Inflammasome pathway",3.12,0.238,-1,"MYD88","myeloid differentiation primary response 88","Plasma Membrane","other",0.0019091989,0.0009046913,"down",1.3930262,-1.3930262,-0.47822243]
["Inflammasome pathway",3.12,0.238,-1,"CASP1","caspase 1","Cytoplasm","peptidase",0.0010976536,0.00020770791,"down",1.8456633,-1.8456633,-0.88413936]
["Inflammasome pathway",3.12,0.238,-1,"NEK7","NIMA related kinase 7","Nucleus","kinase",0.0026042238,0.0015119822,"down",1.8979315,-1.8979315,-0.92442787]
["Inflammasome pathway",3.12,0.238,-1,"PANX1","pannexin 1","Plasma Membrane","transporter",0.0016202792,0.00063036644,"up",1.3148646,1.3148646,0.39491427]
["Nitric Oxide Signaling in the Cardiovascular System",3.1,0.106,1.155,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Nitric Oxide Signaling in the Cardiovascular System",3.1,0.106,1.155,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Nitric Oxide Signaling in the Cardiovascular System",3.1,0.106,1.155,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Nitric Oxide Signaling in the Cardiovascular System",3.1,0.106,1.155,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Nitric Oxide Signaling in the Cardiovascular System",3.1,0.106,1.155,"PDE3B","phosphodiesterase 3B","Cytoplasm","enzyme",0.0026252405,0.0015308249,"up",1.3255126,1.3255126,0.40655044]
["Nitric Oxide Signaling in the Cardiovascular System",3.1,0.106,1.155,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Nitric Oxide Signaling in the Cardiovascular System",3.1,0.106,1.155,"CAV1","caveolin 1","Plasma Membrane","transmembrane receptor",0.0014512807,0.00046188477,"up",1.5792397,1.5792397,0.6592302]
["Nitric Oxide Signaling in the Cardiovascular System",3.1,0.106,1.155,"PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Nitric Oxide Signaling in the Cardiovascular System",3.1,0.106,1.155,"HSP90AA1","heat shock protein 90kDa alpha family class A member 1","Cytoplasm","enzyme",0.0005783946,2.0937947e-05,"up",1.5556576,1.5556576,0.63752455]
["Nitric Oxide Signaling in the Cardiovascular System",3.1,0.106,1.155,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Nitric Oxide Signaling in the Cardiovascular System",3.1,0.106,1.155,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Nitric Oxide Signaling in the Cardiovascular System",3.1,0.106,1.155,"ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["Cholecystokinin/Gastrin-mediated Signaling",2.98,0.109,"NaN","ROCK2","Rho associated coiled-coil containing protein kinase 2","Cytoplasm","kinase",0.0010184328,0.00016622998,"up",1.3479002,1.3479002,0.43071362]
["Cholecystokinin/Gastrin-mediated Signaling",2.98,0.109,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Cholecystokinin/Gastrin-mediated Signaling",2.98,0.109,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Cholecystokinin/Gastrin-mediated Signaling",2.98,0.109,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Cholecystokinin/Gastrin-mediated Signaling",2.98,0.109,"NaN","MEF2D","myocyte enhancer factor 2D","Nucleus","transcription regulator",0.0006217929,3.203251e-05,"down",1.3555743,-1.3555743,-0.43890414]
["Cholecystokinin/Gastrin-mediated Signaling",2.98,0.109,"NaN","MEF2A","myocyte enhancer factor 2A","Nucleus","transcription regulator",0.015937602,0.014585446,"down",1.3274704,-1.3274704,-0.40867972]
["Cholecystokinin/Gastrin-mediated Signaling",2.98,0.109,"NaN","RHOU","ras homolog family member U","Cytoplasm","enzyme",0.0009194498,0.00012193339,"down",1.7715495,-1.7715495,-0.82501173]
["Cholecystokinin/Gastrin-mediated Signaling",2.98,0.109,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Cholecystokinin/Gastrin-mediated Signaling",2.98,0.109,"NaN","PTGS2","prostaglandin-endoperoxide synthase 2","Cytoplasm","enzyme",0.0012584343,0.00031259237,"down",1.4767396,-1.4767396,-0.5624155]
["Cholecystokinin/Gastrin-mediated Signaling",2.98,0.109,"NaN","ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["Cholecystokinin/Gastrin-mediated Signaling",2.98,0.109,"NaN","ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["PAK Signaling",2.98,0.109,0.905,"ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["PAK Signaling",2.98,0.109,0.905,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["PAK Signaling",2.98,0.109,0.905,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["PAK Signaling",2.98,0.109,0.905,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["PAK Signaling",2.98,0.109,0.905,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["PAK Signaling",2.98,0.109,0.905,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["PAK Signaling",2.98,0.109,0.905,"WASL","Wiskott-Aldrich syndrome like","Cytoplasm","other",0.00040977335,6.54692e-06,"up",1.4019742,1.4019742,0.4874598]
["PAK Signaling",2.98,0.109,0.905,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["PAK Signaling",2.98,0.109,0.905,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["PAK Signaling",2.98,0.109,0.905,"LIMK2","LIM domain kinase 2","Cytoplasm","kinase",0.0035328772,0.002318736,"up",1.3875531,1.3875531,0.47254297]
["PAK Signaling",2.98,0.109,0.905,"MYL6B","myosin light chain 6B","Cytoplasm","other",0.0037700427,0.0025393397,"up",1.3426967,1.3426967,0.4251334]
["NGF Signaling",2.97,0.103,0.905,"ROCK2","Rho associated coiled-coil containing protein kinase 2","Cytoplasm","kinase",0.0010184328,0.00016622998,"up",1.3479002,1.3479002,0.43071362]
["NGF Signaling",2.97,0.103,0.905,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["NGF Signaling",2.97,0.103,0.905,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["NGF Signaling",2.97,0.103,0.905,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["NGF Signaling",2.97,0.103,0.905,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["NGF Signaling",2.97,0.103,0.905,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["NGF Signaling",2.97,0.103,0.905,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["NGF Signaling",2.97,0.103,0.905,"RPS6KB2","ribosomal protein S6 kinase B2","Cytoplasm","kinase",0.0016431456,0.0006520507,"down",1.986918,-1.986918,-0.9905323]
["NGF Signaling",2.97,0.103,0.905,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["NGF Signaling",2.97,0.103,0.905,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["NGF Signaling",2.97,0.103,0.905,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["NGF Signaling",2.97,0.103,0.905,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["Adipogenesis pathway",2.94,0.097,"NaN","SAP18","Sin3A associated protein 18kDa","Nucleus","transcription regulator",0.0006217929,3.2134e-05,"down",1.6716334,-1.6716334,-0.74125844]
["Adipogenesis pathway",2.94,0.097,"NaN","FZD10","frizzled class receptor 10","Plasma Membrane","G-protein coupled receptor",0.00084399927,9.184798e-05,"down",1.4670624,-1.4670624,-0.5529302]
["Adipogenesis pathway",2.94,0.097,"NaN","SAP30L","SAP30-like","Nucleus","other",0.0014575268,0.00046826657,"down",1.3737423,-1.3737423,-0.45811144]
["Adipogenesis pathway",2.94,0.097,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Adipogenesis pathway",2.94,0.097,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Adipogenesis pathway",2.94,0.097,"NaN","SENP2","SUMO1/sentrin/SMT3 specific peptidase 2","Nucleus","peptidase",0.0010019254,0.00015893491,"up",1.3148267,1.3148267,0.3948727]
["Adipogenesis pathway",2.94,0.097,"NaN","SMAD5","SMAD family member 5","Nucleus","transcription regulator",0.0014749195,0.00048909907,"down",1.3112969,-1.3112969,-0.3909944]
["Adipogenesis pathway",2.94,0.097,"NaN","FZD1","frizzled class receptor 1","Plasma Membrane","G-protein coupled receptor",0.0036817046,0.002460812,"down",1.529664,-1.529664,-0.6132148]
["Adipogenesis pathway",2.94,0.097,"NaN","CEBPB","CCAAT/enhancer binding protein beta","Nucleus","transcription regulator",0.021593252,0.020254135,"down",1.3026826,-1.3026826,-0.38148564]
["Adipogenesis pathway",2.94,0.097,"NaN","HDAC6","histone deacetylase 6","Nucleus","transcription regulator",0.0060592825,0.0047327504,"up",1.6543902,1.6543902,0.7262995]
["Adipogenesis pathway",2.94,0.097,"NaN","LPL","lipoprotein lipase","Cytoplasm","enzyme",0.0019518846,0.00095576775,"down",1.3136675,-1.3136675,-0.3936002]
["Adipogenesis pathway",2.94,0.097,"NaN","FZD5","frizzled class receptor 5","Plasma Membrane","G-protein coupled receptor",0.0011555209,0.00024123449,"down",1.5153433,-1.5153433,-0.59964466]
["Adipogenesis pathway",2.94,0.097,"NaN","KLF3","Kruppel-like factor 3 (basic)","Nucleus","transcription regulator",0.0021139982,0.0010897743,"up",1.5867121,1.5867121,0.6660404]
["Breast Cancer Regulation by Stathmin1",2.94,0.0837,"NaN","GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["Breast Cancer Regulation by Stathmin1",2.94,0.0837,"NaN","TUBB3","tubulin beta 3 class III","Cytoplasm","other",0.001459056,0.00047059942,"up",1.4351482,1.4351482,0.52119976]
["Breast Cancer Regulation by Stathmin1",2.94,0.0837,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Breast Cancer Regulation by Stathmin1",2.94,0.0837,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Breast Cancer Regulation by Stathmin1",2.94,0.0837,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Breast Cancer Regulation by Stathmin1",2.94,0.0837,"NaN","TUBB2A","tubulin beta 2A class IIa","Cytoplasm","other",0.0026605518,0.0015617278,"up",1.4475315,1.4475315,0.5335947]
["Breast Cancer Regulation by Stathmin1",2.94,0.0837,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Breast Cancer Regulation by Stathmin1",2.94,0.0837,"NaN","LIMK2","LIM domain kinase 2","Cytoplasm","kinase",0.0035328772,0.002318736,"up",1.3875531,1.3875531,0.47254297]
["Breast Cancer Regulation by Stathmin1",2.94,0.0837,"NaN","ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["Breast Cancer Regulation by Stathmin1",2.94,0.0837,"NaN","ROCK2","Rho associated coiled-coil containing protein kinase 2","Cytoplasm","kinase",0.0010184328,0.00016622998,"up",1.3479002,1.3479002,0.43071362]
["Breast Cancer Regulation by Stathmin1",2.94,0.0837,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Breast Cancer Regulation by Stathmin1",2.94,0.0837,"NaN","CCNE1","cyclin E1","Nucleus","transcription regulator",0.0013342145,0.00036659295,"down",2.6488216,-2.6488216,-1.4053507]
["Breast Cancer Regulation by Stathmin1",2.94,0.0837,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Breast Cancer Regulation by Stathmin1",2.94,0.0837,"NaN","CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["Breast Cancer Regulation by Stathmin1",2.94,0.0837,"NaN","CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["Breast Cancer Regulation by Stathmin1",2.94,0.0837,"NaN","PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Breast Cancer Regulation by Stathmin1",2.94,0.0837,"NaN","UHMK1","U2AF homology motif (UHM) kinase 1","Nucleus","kinase",0.0011437805,0.00023514063,"down",2.0135546,-2.0135546,-1.0097445]
["Inhibition of Angiogenesis by TSP1",2.91,0.176,"NaN","TGFBR1","transforming growth factor beta receptor 1","Plasma Membrane","kinase",0.0008942897,0.00011058827,"up",1.5758384,1.5758384,0.65611964]
["Inhibition of Angiogenesis by TSP1",2.91,0.176,"NaN","SDC1","syndecan 1","Plasma Membrane","enzyme",0.001123322,0.00022071275,"up",1.3963997,1.3963997,0.48171198]
["Inhibition of Angiogenesis by TSP1",2.91,0.176,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Inhibition of Angiogenesis by TSP1",2.91,0.176,"NaN","SDC2","syndecan 2","Plasma Membrane","other",0.00067191356,4.108484e-05,"up",1.8298745,1.8298745,0.8717447]
["Inhibition of Angiogenesis by TSP1",2.91,0.176,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Inhibition of Angiogenesis by TSP1",2.91,0.176,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Neuregulin Signaling",2.9,0.114,-0.707,"ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["Neuregulin Signaling",2.9,0.114,-0.707,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Neuregulin Signaling",2.9,0.114,-0.707,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Neuregulin Signaling",2.9,0.114,-0.707,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Neuregulin Signaling",2.9,0.114,-0.707,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Neuregulin Signaling",2.9,0.114,-0.707,"DCN","decorin","Extracellular Space","other",0.0014353773,0.0004506417,"down",1.4550241,-1.4550241,-0.54104304]
["Neuregulin Signaling",2.9,0.114,-0.707,"RPS6KB2","ribosomal protein S6 kinase B2","Cytoplasm","kinase",0.0016431456,0.0006520507,"down",1.986918,-1.986918,-0.9905323]
["Neuregulin Signaling",2.9,0.114,-0.707,"HSP90AA1","heat shock protein 90kDa alpha family class A member 1","Cytoplasm","enzyme",0.0005783946,2.0937947e-05,"up",1.5556576,1.5556576,0.63752455]
["Neuregulin Signaling",2.9,0.114,-0.707,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Neuregulin Signaling",2.9,0.114,-0.707,"PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["Glycine Biosynthesis I",2.89,1,"NaN","SHMT1","serine hydroxymethyltransferase 1","Cytoplasm","enzyme",0.0008942897,0.000111482994,"up",1.4391686,1.4391686,0.5252356]
["Glycine Biosynthesis I",2.89,1,"NaN","SHMT2","serine hydroxymethyltransferase 2","Cytoplasm","enzyme",0.0022647758,0.0012213683,"down",1.6496395,-1.6496395,-0.72215074]
["Chronic Myeloid Leukemia Signaling",2.87,0.106,"NaN","HDAC6","histone deacetylase 6","Nucleus","transcription regulator",0.0060592825,0.0047327504,"up",1.6543902,1.6543902,0.7262995]
["Chronic Myeloid Leukemia Signaling",2.87,0.106,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Chronic Myeloid Leukemia Signaling",2.87,0.106,"NaN","IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["Chronic Myeloid Leukemia Signaling",2.87,0.106,"NaN","TGFBR1","transforming growth factor beta receptor 1","Plasma Membrane","kinase",0.0008942897,0.00011058827,"up",1.5758384,1.5758384,0.65611964]
["Chronic Myeloid Leukemia Signaling",2.87,0.106,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Chronic Myeloid Leukemia Signaling",2.87,0.106,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Chronic Myeloid Leukemia Signaling",2.87,0.106,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Chronic Myeloid Leukemia Signaling",2.87,0.106,"NaN","CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["Chronic Myeloid Leukemia Signaling",2.87,0.106,"NaN","CDK6","cyclin-dependent kinase 6","Nucleus","kinase",0.0011555209,0.0002428485,"down",1.6726129,-1.6726129,-0.7421036]
["Chronic Myeloid Leukemia Signaling",2.87,0.106,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Chronic Myeloid Leukemia Signaling",2.87,0.106,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Colorectal Cancer Metastasis Signaling",2.78,0.0769,-0.471,"GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["Colorectal Cancer Metastasis Signaling",2.78,0.0769,-0.471,"FZD10","frizzled class receptor 10","Plasma Membrane","G-protein coupled receptor",0.00084399927,9.184798e-05,"down",1.4670624,-1.4670624,-0.5529302]
["Colorectal Cancer Metastasis Signaling",2.78,0.0769,-0.471,"TGFBR1","transforming growth factor beta receptor 1","Plasma Membrane","kinase",0.0008942897,0.00011058827,"up",1.5758384,1.5758384,0.65611964]
["Colorectal Cancer Metastasis Signaling",2.78,0.0769,-0.471,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Colorectal Cancer Metastasis Signaling",2.78,0.0769,-0.471,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Colorectal Cancer Metastasis Signaling",2.78,0.0769,-0.471,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Colorectal Cancer Metastasis Signaling",2.78,0.0769,-0.471,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Colorectal Cancer Metastasis Signaling",2.78,0.0769,-0.471,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Colorectal Cancer Metastasis Signaling",2.78,0.0769,-0.471,"FZD1","frizzled class receptor 1","Plasma Membrane","G-protein coupled receptor",0.0036817046,0.002460812,"down",1.529664,-1.529664,-0.6132148]
["Colorectal Cancer Metastasis Signaling",2.78,0.0769,-0.471,"BIRC5","baculoviral IAP repeat containing 5","Cytoplasm","other",0.0018505693,0.00084797834,"up",1.5707992,1.5707992,0.6514988]
["Colorectal Cancer Metastasis Signaling",2.78,0.0769,-0.471,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Colorectal Cancer Metastasis Signaling",2.78,0.0769,-0.471,"APPL1","adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1","Cytoplasm","other",0.0016089604,0.0006085526,"up",1.4972963,1.4972963,0.5823598]
["Colorectal Cancer Metastasis Signaling",2.78,0.0769,-0.471,"CDH1","cadherin 1","Plasma Membrane","other",0.0017019173,0.0006999703,"up",1.452055,1.452055,0.5380961]
["Colorectal Cancer Metastasis Signaling",2.78,0.0769,-0.471,"ARRB1","arrestin beta 1","Cytoplasm","other",0.0032341068,0.0020446463,"up",1.4974334,1.4974334,0.5824919]
["Colorectal Cancer Metastasis Signaling",2.78,0.0769,-0.471,"RHOU","ras homolog family member U","Cytoplasm","enzyme",0.0009194498,0.00012193339,"down",1.7715495,-1.7715495,-0.82501173]
["Colorectal Cancer Metastasis Signaling",2.78,0.0769,-0.471,"PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Colorectal Cancer Metastasis Signaling",2.78,0.0769,-0.471,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Colorectal Cancer Metastasis Signaling",2.78,0.0769,-0.471,"FZD5","frizzled class receptor 5","Plasma Membrane","G-protein coupled receptor",0.0011555209,0.00024123449,"down",1.5153433,-1.5153433,-0.59964466]
["Colorectal Cancer Metastasis Signaling",2.78,0.0769,-0.471,"PTGS2","prostaglandin-endoperoxide synthase 2","Cytoplasm","enzyme",0.0012584343,0.00031259237,"down",1.4767396,-1.4767396,-0.5624155]
["Estrogen-Dependent Breast Cancer Signaling",2.75,0.117,1.414,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Estrogen-Dependent Breast Cancer Signaling",2.75,0.117,1.414,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Estrogen-Dependent Breast Cancer Signaling",2.75,0.117,1.414,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Estrogen-Dependent Breast Cancer Signaling",2.75,0.117,1.414,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Estrogen-Dependent Breast Cancer Signaling",2.75,0.117,1.414,"IGF1R","insulin like growth factor 1 receptor","Plasma Membrane","transmembrane receptor",0.0016147236,0.0006161828,"up",1.8701973,1.8701973,0.90319043]
["Estrogen-Dependent Breast Cancer Signaling",2.75,0.117,1.414,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Estrogen-Dependent Breast Cancer Signaling",2.75,0.117,1.414,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Estrogen-Dependent Breast Cancer Signaling",2.75,0.117,1.414,"AKR1C4","aldo-keto reductase family 1, member C4","Cytoplasm","enzyme",0.0008743986,0.000103180544,"up",1.8595277,1.8595277,0.8949362]
["Estrogen-Dependent Breast Cancer Signaling",2.75,0.117,1.414,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["IL-17A Signaling in Airway Cells",2.75,0.117,1.667,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["IL-17A Signaling in Airway Cells",2.75,0.117,1.667,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["IL-17A Signaling in Airway Cells",2.75,0.117,1.667,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["IL-17A Signaling in Airway Cells",2.75,0.117,1.667,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["IL-17A Signaling in Airway Cells",2.75,0.117,1.667,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["IL-17A Signaling in Airway Cells",2.75,0.117,1.667,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["IL-17A Signaling in Airway Cells",2.75,0.117,1.667,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["IL-17A Signaling in Airway Cells",2.75,0.117,1.667,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["IL-17A Signaling in Airway Cells",2.75,0.117,1.667,"PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["PCP pathway",2.73,0.127,0,"ROCK2","Rho associated coiled-coil containing protein kinase 2","Cytoplasm","kinase",0.0010184328,0.00016622998,"up",1.3479002,1.3479002,0.43071362]
["PCP pathway",2.73,0.127,0,"FZD10","frizzled class receptor 10","Plasma Membrane","G-protein coupled receptor",0.00084399927,9.184798e-05,"down",1.4670624,-1.4670624,-0.5529302]
["PCP pathway",2.73,0.127,0,"SDC1","syndecan 1","Plasma Membrane","enzyme",0.001123322,0.00022071275,"up",1.3963997,1.3963997,0.48171198]
["PCP pathway",2.73,0.127,0,"SDC2","syndecan 2","Plasma Membrane","other",0.00067191356,4.108484e-05,"up",1.8298745,1.8298745,0.8717447]
["PCP pathway",2.73,0.127,0,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["PCP pathway",2.73,0.127,0,"FZD5","frizzled class receptor 5","Plasma Membrane","G-protein coupled receptor",0.0011555209,0.00024123449,"down",1.5153433,-1.5153433,-0.59964466]
["PCP pathway",2.73,0.127,0,"FZD1","frizzled class receptor 1","Plasma Membrane","G-protein coupled receptor",0.0036817046,0.002460812,"down",1.529664,-1.529664,-0.6132148]
["PCP pathway",2.73,0.127,0,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["CD40 Signaling",2.71,0.115,0.707,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["CD40 Signaling",2.71,0.115,0.707,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["CD40 Signaling",2.71,0.115,0.707,"ATF1","activating transcription factor 1","Nucleus","transcription regulator",0.0070709703,0.005685401,"down",1.3784643,-1.3784643,-0.46306193]
["CD40 Signaling",2.71,0.115,0.707,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["CD40 Signaling",2.71,0.115,0.707,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["CD40 Signaling",2.71,0.115,0.707,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["CD40 Signaling",2.71,0.115,0.707,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["CD40 Signaling",2.71,0.115,0.707,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["CD40 Signaling",2.71,0.115,0.707,"PTGS2","prostaglandin-endoperoxide synthase 2","Cytoplasm","enzyme",0.0012584343,0.00031259237,"down",1.4767396,-1.4767396,-0.5624155]
["Endometrial Cancer Signaling",2.69,0.125,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Endometrial Cancer Signaling",2.69,0.125,"NaN","CDH1","cadherin 1","Plasma Membrane","other",0.0017019173,0.0006999703,"up",1.452055,1.452055,0.5380961]
["Endometrial Cancer Signaling",2.69,0.125,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Endometrial Cancer Signaling",2.69,0.125,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Endometrial Cancer Signaling",2.69,0.125,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Endometrial Cancer Signaling",2.69,0.125,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Endometrial Cancer Signaling",2.69,0.125,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Endometrial Cancer Signaling",2.69,0.125,"NaN","PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["Sertoli Cell-Sertoli Cell Junction Signaling",2.69,0.0843,"NaN","ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["Sertoli Cell-Sertoli Cell Junction Signaling",2.69,0.0843,"NaN","TUBB3","tubulin beta 3 class III","Cytoplasm","other",0.001459056,0.00047059942,"up",1.4351482,1.4351482,0.52119976]
["Sertoli Cell-Sertoli Cell Junction Signaling",2.69,0.0843,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Sertoli Cell-Sertoli Cell Junction Signaling",2.69,0.0843,"NaN","TUBB2A","tubulin beta 2A class IIa","Cytoplasm","other",0.0026605518,0.0015617278,"up",1.4475315,1.4475315,0.5335947]
["Sertoli Cell-Sertoli Cell Junction Signaling",2.69,0.0843,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Sertoli Cell-Sertoli Cell Junction Signaling",2.69,0.0843,"NaN","MLLT4","myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4","Nucleus","other",0.0013056329,0.00034460775,"up",1.7435131,1.7435131,0.8019972]
["Sertoli Cell-Sertoli Cell Junction Signaling",2.69,0.0843,"NaN","ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["Sertoli Cell-Sertoli Cell Junction Signaling",2.69,0.0843,"NaN","PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["Sertoli Cell-Sertoli Cell Junction Signaling",2.69,0.0843,"NaN","CDH1","cadherin 1","Plasma Membrane","other",0.0017019173,0.0006999703,"up",1.452055,1.452055,0.5380961]
["Sertoli Cell-Sertoli Cell Junction Signaling",2.69,0.0843,"NaN","CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["Sertoli Cell-Sertoli Cell Junction Signaling",2.69,0.0843,"NaN","CGN","cingulin","Plasma Membrane","other",0.0016183598,0.0006279682,"up",1.3458213,1.3458213,0.42848682]
["Sertoli Cell-Sertoli Cell Junction Signaling",2.69,0.0843,"NaN","PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Sertoli Cell-Sertoli Cell Junction Signaling",2.69,0.0843,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Sertoli Cell-Sertoli Cell Junction Signaling",2.69,0.0843,"NaN","MTMR2","myotubularin related protein 2","Cytoplasm","phosphatase",0.001395873,0.000419132,"up",1.3830658,1.3830658,0.46786982]
["Sertoli Cell-Sertoli Cell Junction Signaling",2.69,0.0843,"NaN","NECTIN2","nectin cell adhesion molecule 2","Plasma Membrane","transmembrane receptor",0.0023623689,0.0013073402,"up",1.3960435,1.3960435,0.48134392]
["Glioma Signaling",2.68,0.1,0.905,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Glioma Signaling",2.68,0.1,0.905,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Glioma Signaling",2.68,0.1,0.905,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Glioma Signaling",2.68,0.1,0.905,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Glioma Signaling",2.68,0.1,0.905,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Glioma Signaling",2.68,0.1,0.905,"CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["Glioma Signaling",2.68,0.1,0.905,"IGF1R","insulin like growth factor 1 receptor","Plasma Membrane","transmembrane receptor",0.0016147236,0.0006161828,"up",1.8701973,1.8701973,0.90319043]
["Glioma Signaling",2.68,0.1,0.905,"CDK6","cyclin-dependent kinase 6","Nucleus","kinase",0.0011555209,0.0002428485,"down",1.6726129,-1.6726129,-0.7421036]
["Glioma Signaling",2.68,0.1,0.905,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Glioma Signaling",2.68,0.1,0.905,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Glioma Signaling",2.68,0.1,0.905,"PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["Antiproliferative Role of TOB in T Cell Signaling",2.67,0.192,"NaN","CCNE1","cyclin E1","Nucleus","transcription regulator",0.0013342145,0.00036659295,"down",2.6488216,-2.6488216,-1.4053507]
["Antiproliferative Role of TOB in T Cell Signaling",2.67,0.192,"NaN","TGFBR1","transforming growth factor beta receptor 1","Plasma Membrane","kinase",0.0008942897,0.00011058827,"up",1.5758384,1.5758384,0.65611964]
["Antiproliferative Role of TOB in T Cell Signaling",2.67,0.192,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Antiproliferative Role of TOB in T Cell Signaling",2.67,0.192,"NaN","TOB1","transducer of ERBB2, 1","Nucleus","transcription regulator",0.0027434009,0.001628082,"down",1.7747058,-1.7747058,-0.82757986]
["Antiproliferative Role of TOB in T Cell Signaling",2.67,0.192,"NaN","SKP2","S-phase kinase-associated protein 2, E3 ubiquitin protein ligase","Nucleus","enzyme",0.0014867174,0.000499228,"up",1.348095,1.348095,0.4309222]
["IL-8 Signaling",2.66,0.0812,0.535,"GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["IL-8 Signaling",2.66,0.0812,0.535,"CXCL8","C-X-C motif chemokine ligand 8","Extracellular Space","cytokine",0.0011259156,0.00022286079,"down",1.5851029,-1.5851029,-0.66457653]
["IL-8 Signaling",2.66,0.0812,0.535,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["IL-8 Signaling",2.66,0.0812,0.535,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["IL-8 Signaling",2.66,0.0812,0.535,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["IL-8 Signaling",2.66,0.0812,0.535,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["IL-8 Signaling",2.66,0.0812,0.535,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["IL-8 Signaling",2.66,0.0812,0.535,"LIMK2","LIM domain kinase 2","Cytoplasm","kinase",0.0035328772,0.002318736,"up",1.3875531,1.3875531,0.47254297]
["IL-8 Signaling",2.66,0.0812,0.535,"ROCK2","Rho associated coiled-coil containing protein kinase 2","Cytoplasm","kinase",0.0010184328,0.00016622998,"up",1.3479002,1.3479002,0.43071362]
["IL-8 Signaling",2.66,0.0812,0.535,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["IL-8 Signaling",2.66,0.0812,0.535,"CDH1","cadherin 1","Plasma Membrane","other",0.0017019173,0.0006999703,"up",1.452055,1.452055,0.5380961]
["IL-8 Signaling",2.66,0.0812,0.535,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["IL-8 Signaling",2.66,0.0812,0.535,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["IL-8 Signaling",2.66,0.0812,0.535,"RHOU","ras homolog family member U","Cytoplasm","enzyme",0.0009194498,0.00012193339,"down",1.7715495,-1.7715495,-0.82501173]
["IL-8 Signaling",2.66,0.0812,0.535,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["IL-8 Signaling",2.66,0.0812,0.535,"PTGS2","prostaglandin-endoperoxide synthase 2","Cytoplasm","enzyme",0.0012584343,0.00031259237,"down",1.4767396,-1.4767396,-0.5624155]
["Renal Cell Carcinoma Signaling",2.59,0.111,0.707,"MET","MET proto-oncogene, receptor tyrosine kinase","Plasma Membrane","kinase",0.0008691947,0.00010051858,"up",1.5833938,1.5833938,0.66302013]
["Renal Cell Carcinoma Signaling",2.59,0.111,0.707,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Renal Cell Carcinoma Signaling",2.59,0.111,0.707,"SLC2A1","solute carrier family 2 member 1","Plasma Membrane","transporter",0.0010998568,0.00021028184,"down",1.3829497,-1.3829497,-0.4677487]
["Renal Cell Carcinoma Signaling",2.59,0.111,0.707,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Renal Cell Carcinoma Signaling",2.59,0.111,0.707,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Renal Cell Carcinoma Signaling",2.59,0.111,0.707,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["Renal Cell Carcinoma Signaling",2.59,0.111,0.707,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Renal Cell Carcinoma Signaling",2.59,0.111,0.707,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Renal Cell Carcinoma Signaling",2.59,0.111,0.707,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Integrin Signaling",2.59,0.0776,1,"RAP2B","RAP2B, member of RAS oncogene family","Plasma Membrane","enzyme",0.0005464768,1.2239901e-05,"down",1.9869581,-1.9869581,-0.9905615]
["Integrin Signaling",2.59,0.0776,1,"ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["Integrin Signaling",2.59,0.0776,1,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Integrin Signaling",2.59,0.0776,1,"ASAP1","ArfGAP with SH3 domain, ankyrin repeat and PH domain 1","Plasma Membrane","other",0.0013318703,0.0003648017,"up",1.5520838,1.5520838,0.6342065]
["Integrin Signaling",2.59,0.0776,1,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Integrin Signaling",2.59,0.0776,1,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Integrin Signaling",2.59,0.0776,1,"WASL","Wiskott-Aldrich syndrome like","Cytoplasm","other",0.00040977335,6.54692e-06,"up",1.4019742,1.4019742,0.4874598]
["Integrin Signaling",2.59,0.0776,1,"RALB","v-ral simian leukemia viral oncogene homolog B","Cytoplasm","enzyme",0.0022762846,0.0012371538,"up",1.7571107,1.7571107,0.81320506]
["Integrin Signaling",2.59,0.0776,1,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Integrin Signaling",2.59,0.0776,1,"ITGB8","integrin subunit beta 8","Plasma Membrane","other",0.0039384346,0.0026866843,"up",1.8310404,1.8310404,0.8726636]
["Integrin Signaling",2.59,0.0776,1,"PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["Integrin Signaling",2.59,0.0776,1,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Integrin Signaling",2.59,0.0776,1,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["Integrin Signaling",2.59,0.0776,1,"RHOU","ras homolog family member U","Cytoplasm","enzyme",0.0009194498,0.00012193339,"down",1.7715495,-1.7715495,-0.82501173]
["Integrin Signaling",2.59,0.0776,1,"CAV1","caveolin 1","Plasma Membrane","transmembrane receptor",0.0014512807,0.00046188477,"up",1.5792397,1.5792397,0.6592302]
["Integrin Signaling",2.59,0.0776,1,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Integrin Signaling",2.59,0.0776,1,"NEDD9","neural precursor cell expressed, developmentally down-regulated 9","Nucleus","other",0.0016089604,0.00060944003,"up",1.5488138,1.5488138,0.6311637]
["CXCR4 Signaling",2.57,0.0848,0.832,"ROCK2","Rho associated coiled-coil containing protein kinase 2","Cytoplasm","kinase",0.0010184328,0.00016622998,"up",1.3479002,1.3479002,0.43071362]
["CXCR4 Signaling",2.57,0.0848,0.832,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["CXCR4 Signaling",2.57,0.0848,0.832,"GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["CXCR4 Signaling",2.57,0.0848,0.832,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["CXCR4 Signaling",2.57,0.0848,0.832,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["CXCR4 Signaling",2.57,0.0848,0.832,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["CXCR4 Signaling",2.57,0.0848,0.832,"CXCR4","C-X-C motif chemokine receptor 4","Plasma Membrane","G-protein coupled receptor",0.0018305046,0.00083504117,"down",1.3248457,-1.3248457,-0.4058243]
["CXCR4 Signaling",2.57,0.0848,0.832,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["CXCR4 Signaling",2.57,0.0848,0.832,"RHOU","ras homolog family member U","Cytoplasm","enzyme",0.0009194498,0.00012193339,"down",1.7715495,-1.7715495,-0.82501173]
["CXCR4 Signaling",2.57,0.0848,0.832,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["CXCR4 Signaling",2.57,0.0848,0.832,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["CXCR4 Signaling",2.57,0.0848,0.832,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["CXCR4 Signaling",2.57,0.0848,0.832,"MYL6B","myosin light chain 6B","Cytoplasm","other",0.0037700427,0.0025393397,"up",1.3426967,1.3426967,0.4251334]
["CXCR4 Signaling",2.57,0.0848,0.832,"ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["Semaphorin Signaling in Neurons",2.55,0.132,"NaN","ROCK2","Rho associated coiled-coil containing protein kinase 2","Cytoplasm","kinase",0.0010184328,0.00016622998,"up",1.3479002,1.3479002,0.43071362]
["Semaphorin Signaling in Neurons",2.55,0.132,"NaN","ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["Semaphorin Signaling in Neurons",2.55,0.132,"NaN","MET","MET proto-oncogene, receptor tyrosine kinase","Plasma Membrane","kinase",0.0008691947,0.00010051858,"up",1.5833938,1.5833938,0.66302013]
["Semaphorin Signaling in Neurons",2.55,0.132,"NaN","CRMP1","collapsin response mediator protein 1","Cytoplasm","enzyme",0.0028132095,0.0016852017,"up",1.7426248,1.7426248,0.80126196]
["Semaphorin Signaling in Neurons",2.55,0.132,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Semaphorin Signaling in Neurons",2.55,0.132,"NaN","RHOU","ras homolog family member U","Cytoplasm","enzyme",0.0009194498,0.00012193339,"down",1.7715495,-1.7715495,-0.82501173]
["Semaphorin Signaling in Neurons",2.55,0.132,"NaN","LIMK2","LIM domain kinase 2","Cytoplasm","kinase",0.0035328772,0.002318736,"up",1.3875531,1.3875531,0.47254297]
["Superpathway of Cholesterol Biosynthesis",2.53,0.179,"NaN","SQLE","squalene epoxidase","Cytoplasm","enzyme",0.00069462875,4.9444014e-05,"up",1.517981,1.517981,0.6021538]
["Superpathway of Cholesterol Biosynthesis",2.53,0.179,"NaN","PMVK","phosphomevalonate kinase","Cytoplasm","kinase",0.0015215367,0.0005270031,"down",1.3550662,-1.3550662,-0.4383633]
["Superpathway of Cholesterol Biosynthesis",2.53,0.179,"NaN","MSMO1","methylsterol monooxygenase 1","Cytoplasm","enzyme",0.0012443048,0.00030560244,"up",1.4843444,1.4843444,0.5698258]
["Superpathway of Cholesterol Biosynthesis",2.53,0.179,"NaN","HMGCR","3-hydroxy-3-methylglutaryl-CoA reductase","Cytoplasm","enzyme",0.0014677041,0.00048228173,"up",1.3671681,1.3671681,0.4511906]
["Superpathway of Cholesterol Biosynthesis",2.53,0.179,"NaN","GGPS1","geranylgeranyl diphosphate synthase 1","Cytoplasm","enzyme",0.0020834338,0.0010650456,"up",1.3196927,1.3196927,0.40020207]
["FAK Signaling",2.51,0.101,"NaN","ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["FAK Signaling",2.51,0.101,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["FAK Signaling",2.51,0.101,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["FAK Signaling",2.51,0.101,"NaN","ASAP1","ArfGAP with SH3 domain, ankyrin repeat and PH domain 1","Plasma Membrane","other",0.0013318703,0.0003648017,"up",1.5520838,1.5520838,0.6342065]
["FAK Signaling",2.51,0.101,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["FAK Signaling",2.51,0.101,"NaN","HMMR","hyaluronan mediated motility receptor","Plasma Membrane","transmembrane receptor",0.0012233602,0.00028587523,"up",1.4464353,1.4464353,0.5325018]
["FAK Signaling",2.51,0.101,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["FAK Signaling",2.51,0.101,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["FAK Signaling",2.51,0.101,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["FAK Signaling",2.51,0.101,"NaN","PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["Folate Transformations I",2.48,0.333,"NaN","SHMT1","serine hydroxymethyltransferase 1","Cytoplasm","enzyme",0.0008942897,0.000111482994,"up",1.4391686,1.4391686,0.5252356]
["Folate Transformations I",2.48,0.333,"NaN","MTR","5-methyltetrahydrofolate-homocysteine methyltransferase","Cytoplasm","enzyme",0.0021334826,0.0011126819,"down",1.3912218,-1.3912218,-0.4763524]
["Folate Transformations I",2.48,0.333,"NaN","SHMT2","serine hydroxymethyltransferase 2","Cytoplasm","enzyme",0.0022647758,0.0012213683,"down",1.6496395,-1.6496395,-0.72215074]
["Rac Signaling",2.47,0.094,0.632,"ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["Rac Signaling",2.47,0.094,0.632,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Rac Signaling",2.47,0.094,0.632,"MCF2L","MCF.2 cell line derived transforming sequence like","Cytoplasm","other",0.005381051,0.004029995,"up",1.3208132,1.3208132,0.4014264]
["Rac Signaling",2.47,0.094,0.632,"ABI2","abl-interactor 2","Cytoplasm","other",0.001550606,0.0005515692,"up",1.458196,1.458196,0.5441847]
["Rac Signaling",2.47,0.094,0.632,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Rac Signaling",2.47,0.094,0.632,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Rac Signaling",2.47,0.094,0.632,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Rac Signaling",2.47,0.094,0.632,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["Rac Signaling",2.47,0.094,0.632,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Rac Signaling",2.47,0.094,0.632,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Rac Signaling",2.47,0.094,0.632,"LIMK2","LIM domain kinase 2","Cytoplasm","kinase",0.0035328772,0.002318736,"up",1.3875531,1.3875531,0.47254297]
["Role of CHK Proteins in Cell Cycle Checkpoint Control",2.46,0.127,0,"PCNA","proliferating cell nuclear antigen","Nucleus","enzyme",0.0032386743,0.0020517183,"down",1.3257968,-1.3257968,-0.40685973]
["Role of CHK Proteins in Cell Cycle Checkpoint Control",2.46,0.127,0,"CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["Role of CHK Proteins in Cell Cycle Checkpoint Control",2.46,0.127,0,"ATMIN","ATM interactor","Nucleus","other",0.008374895,0.006935798,"down",1.6261339,-1.6261339,-0.70144606]
["Role of CHK Proteins in Cell Cycle Checkpoint Control",2.46,0.127,0,"RFC1","replication factor C subunit 1","Nucleus","transcription regulator",0.011040431,0.009618774,"up",1.3221459,1.3221459,0.4028814]
["Role of CHK Proteins in Cell Cycle Checkpoint Control",2.46,0.127,0,"CHEK2","checkpoint kinase 2","Nucleus","kinase",0.0028598784,0.0017272087,"up",1.3150214,1.3150214,0.39508626]
["Role of CHK Proteins in Cell Cycle Checkpoint Control",2.46,0.127,0,"CHEK1","checkpoint kinase 1","Nucleus","kinase",0.0010877973,0.00019520131,"up",1.4226359,1.4226359,0.5085665]
["Role of CHK Proteins in Cell Cycle Checkpoint Control",2.46,0.127,0,"RAD1","RAD1 checkpoint DNA exonuclease","Nucleus","enzyme",0.0015215367,0.00052814756,"down",1.6791438,-1.6791438,-0.7477258]
["Axonal Guidance Signaling",2.44,0.0625,"NaN","FZD10","frizzled class receptor 10","Plasma Membrane","G-protein coupled receptor",0.00084399927,9.184798e-05,"down",1.4670624,-1.4670624,-0.5529302]
["Axonal Guidance Signaling",2.44,0.0625,"NaN","GLI2","GLI family zinc finger 2","Nucleus","transcription regulator",0.0009526495,0.00013251757,"down",1.5357528,-1.5357528,-0.61894596]
["Axonal Guidance Signaling",2.44,0.0625,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Axonal Guidance Signaling",2.44,0.0625,"NaN","WASL","Wiskott-Aldrich syndrome like","Cytoplasm","other",0.00040977335,6.54692e-06,"up",1.4019742,1.4019742,0.4874598]
["Axonal Guidance Signaling",2.44,0.0625,"NaN","LIMK2","LIM domain kinase 2","Cytoplasm","kinase",0.0035328772,0.002318736,"up",1.3875531,1.3875531,0.47254297]
["Axonal Guidance Signaling",2.44,0.0625,"NaN","MYL6B","myosin light chain 6B","Cytoplasm","other",0.0037700427,0.0025393397,"up",1.3426967,1.3426967,0.4251334]
["Axonal Guidance Signaling",2.44,0.0625,"NaN","FZD1","frizzled class receptor 1","Plasma Membrane","G-protein coupled receptor",0.0036817046,0.002460812,"down",1.529664,-1.529664,-0.6132148]
["Axonal Guidance Signaling",2.44,0.0625,"NaN","ROCK2","Rho associated coiled-coil containing protein kinase 2","Cytoplasm","kinase",0.0010184328,0.00016622998,"up",1.3479002,1.3479002,0.43071362]
["Axonal Guidance Signaling",2.44,0.0625,"NaN","SDC2","syndecan 2","Plasma Membrane","other",0.00067191356,4.108484e-05,"up",1.8298745,1.8298745,0.8717447]
["Axonal Guidance Signaling",2.44,0.0625,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Axonal Guidance Signaling",2.44,0.0625,"NaN","GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["Axonal Guidance Signaling",2.44,0.0625,"NaN","ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["Axonal Guidance Signaling",2.44,0.0625,"NaN","TUBB3","tubulin beta 3 class III","Cytoplasm","other",0.001459056,0.00047059942,"up",1.4351482,1.4351482,0.52119976]
["Axonal Guidance Signaling",2.44,0.0625,"NaN","CXCR4","C-X-C motif chemokine receptor 4","Plasma Membrane","G-protein coupled receptor",0.0018305046,0.00083504117,"down",1.3248457,-1.3248457,-0.4058243]
["Axonal Guidance Signaling",2.44,0.0625,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Axonal Guidance Signaling",2.44,0.0625,"NaN","SEMA5A","semaphorin 5A","Plasma Membrane","transmembrane receptor",0.0055560446,0.0042113,"up",1.3515949,1.3515949,0.43466282]
["Axonal Guidance Signaling",2.44,0.0625,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Axonal Guidance Signaling",2.44,0.0625,"NaN","TUBB2A","tubulin beta 2A class IIa","Cytoplasm","other",0.0026605518,0.0015617278,"up",1.4475315,1.4475315,0.5335947]
["Axonal Guidance Signaling",2.44,0.0625,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Axonal Guidance Signaling",2.44,0.0625,"NaN","EFNA1","ephrin A1","Plasma Membrane","other",0.001983807,0.000985738,"up",1.3843216,1.3843216,0.4691791]
["Axonal Guidance Signaling",2.44,0.0625,"NaN","MET","MET proto-oncogene, receptor tyrosine kinase","Plasma Membrane","kinase",0.0008691947,0.00010051858,"up",1.5833938,1.5833938,0.66302013]
["Axonal Guidance Signaling",2.44,0.0625,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Axonal Guidance Signaling",2.44,0.0625,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Axonal Guidance Signaling",2.44,0.0625,"NaN","ADAM12","ADAM metallopeptidase domain 12","Plasma Membrane","peptidase",0.0039314847,0.0026751703,"down",1.4494704,-1.4494704,-0.53552586]
["Axonal Guidance Signaling",2.44,0.0625,"NaN","CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["Axonal Guidance Signaling",2.44,0.0625,"NaN","PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Axonal Guidance Signaling",2.44,0.0625,"NaN","FZD5","frizzled class receptor 5","Plasma Membrane","G-protein coupled receptor",0.0011555209,0.00024123449,"down",1.5153433,-1.5153433,-0.59964466]
["Axonal Guidance Signaling",2.44,0.0625,"NaN","BMP6","bone morphogenetic protein 6","Extracellular Space","growth factor",0.0012361597,0.00030026503,"up",1.359715,1.359715,0.44330427]
["Glioma Invasiveness Signaling",2.44,0.114,0,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Glioma Invasiveness Signaling",2.44,0.114,0,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Glioma Invasiveness Signaling",2.44,0.114,0,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Glioma Invasiveness Signaling",2.44,0.114,0,"HMMR","hyaluronan mediated motility receptor","Plasma Membrane","transmembrane receptor",0.0012233602,0.00028587523,"up",1.4464353,1.4464353,0.5325018]
["Glioma Invasiveness Signaling",2.44,0.114,0,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Glioma Invasiveness Signaling",2.44,0.114,0,"RHOU","ras homolog family member U","Cytoplasm","enzyme",0.0009194498,0.00012193339,"down",1.7715495,-1.7715495,-0.82501173]
["Glioma Invasiveness Signaling",2.44,0.114,0,"PLAUR","plasminogen activator, urokinase receptor","Plasma Membrane","transmembrane receptor",0.0010741793,0.00018365598,"down",1.485067,-1.485067,-0.57052803]
["Glioma Invasiveness Signaling",2.44,0.114,0,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Virus Entry via Endocytic Pathways",2.42,0.098,"NaN","ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["Virus Entry via Endocytic Pathways",2.42,0.098,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Virus Entry via Endocytic Pathways",2.42,0.098,"NaN","CD55","CD55 molecule (Cromer blood group)","Plasma Membrane","other",0.0022323814,0.0011921417,"down",1.4334465,-1.4334465,-0.5194881]
["Virus Entry via Endocytic Pathways",2.42,0.098,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Virus Entry via Endocytic Pathways",2.42,0.098,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Virus Entry via Endocytic Pathways",2.42,0.098,"NaN","CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["Virus Entry via Endocytic Pathways",2.42,0.098,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Virus Entry via Endocytic Pathways",2.42,0.098,"NaN","CAV1","caveolin 1","Plasma Membrane","transmembrane receptor",0.0014512807,0.00046188477,"up",1.5792397,1.5792397,0.6592302]
["Virus Entry via Endocytic Pathways",2.42,0.098,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Virus Entry via Endocytic Pathways",2.42,0.098,"NaN","ITGB8","integrin subunit beta 8","Plasma Membrane","other",0.0039384346,0.0026866843,"up",1.8310404,1.8310404,0.8726636]
["NF-κB Activation by Viruses",2.42,0.105,0.333,"ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["NF-κB Activation by Viruses",2.42,0.105,0.333,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["NF-κB Activation by Viruses",2.42,0.105,0.333,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["NF-κB Activation by Viruses",2.42,0.105,0.333,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["NF-κB Activation by Viruses",2.42,0.105,0.333,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["NF-κB Activation by Viruses",2.42,0.105,0.333,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["NF-κB Activation by Viruses",2.42,0.105,0.333,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["NF-κB Activation by Viruses",2.42,0.105,0.333,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["NF-κB Activation by Viruses",2.42,0.105,0.333,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["TGF-β Signaling",2.38,0.103,0.333,"TGFBR1","transforming growth factor beta receptor 1","Plasma Membrane","kinase",0.0008942897,0.00011058827,"up",1.5758384,1.5758384,0.65611964]
["TGF-β Signaling",2.38,0.103,0.333,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["TGF-β Signaling",2.38,0.103,0.333,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["TGF-β Signaling",2.38,0.103,0.333,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["TGF-β Signaling",2.38,0.103,0.333,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["TGF-β Signaling",2.38,0.103,0.333,"SMURF2","SMAD specific E3 ubiquitin protein ligase 2","Cytoplasm","enzyme",0.0017505207,0.0007564604,"up",1.4427907,1.4427907,0.52886206]
["TGF-β Signaling",2.38,0.103,0.333,"SMAD5","SMAD family member 5","Nucleus","transcription regulator",0.0014749195,0.00048909907,"down",1.3112969,-1.3112969,-0.3909944]
["TGF-β Signaling",2.38,0.103,0.333,"SERPINE1","serpin family E member 1","Extracellular Space","other",0.0016010772,0.00060374127,"up",1.3806411,1.3806411,0.46533832]
["TGF-β Signaling",2.38,0.103,0.333,"HNF4A","hepatocyte nuclear factor 4 alpha","Nucleus","transcription regulator",0.0018693322,0.0008653767,"up",1.4698008,1.4698008,0.5556207]
["eNOS Signaling",2.38,0.0839,0.333,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["eNOS Signaling",2.38,0.0839,0.333,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["eNOS Signaling",2.38,0.0839,0.333,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["eNOS Signaling",2.38,0.0839,0.333,"ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["eNOS Signaling",2.38,0.0839,0.333,"HSPA5","heat shock protein family A (Hsp70) member 5","Cytoplasm","enzyme",0.007907775,0.006494456,"down",1.3693051,-1.3693051,-0.45344397]
["eNOS Signaling",2.38,0.0839,0.333,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["eNOS Signaling",2.38,0.0839,0.333,"AQP3","aquaporin 3 (Gill blood group)","Plasma Membrane","transporter",0.0006380416,3.3248507e-05,"down",1.3773243,-1.3773243,-0.46186832]
["eNOS Signaling",2.38,0.0839,0.333,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["eNOS Signaling",2.38,0.0839,0.333,"PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["eNOS Signaling",2.38,0.0839,0.333,"PRKAA2","protein kinase AMP-activated catalytic subunit alpha 2","Cytoplasm","kinase",0.0014867174,0.0005054725,"up",1.3466656,1.3466656,0.42939165]
["eNOS Signaling",2.38,0.0839,0.333,"CAV1","caveolin 1","Plasma Membrane","transmembrane receptor",0.0014512807,0.00046188477,"up",1.5792397,1.5792397,0.6592302]
["eNOS Signaling",2.38,0.0839,0.333,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["eNOS Signaling",2.38,0.0839,0.333,"HSP90AA1","heat shock protein 90kDa alpha family class A member 1","Cytoplasm","enzyme",0.0005783946,2.0937947e-05,"up",1.5556576,1.5556576,0.63752455]
["GADD45 Signaling",2.37,0.211,"NaN","PCNA","proliferating cell nuclear antigen","Nucleus","enzyme",0.0032386743,0.0020517183,"down",1.3257968,-1.3257968,-0.40685973]
["GADD45 Signaling",2.37,0.211,"NaN","CCNE1","cyclin E1","Nucleus","transcription regulator",0.0013342145,0.00036659295,"down",2.6488216,-2.6488216,-1.4053507]
["GADD45 Signaling",2.37,0.211,"NaN","GADD45B","growth arrest and DNA damage inducible beta","Cytoplasm","other",0.0013662435,0.00038785784,"up",1.6800824,1.6800824,0.748532]
["GADD45 Signaling",2.37,0.211,"NaN","CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["ErbB4 Signaling",2.36,0.111,0,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["ErbB4 Signaling",2.36,0.111,0,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["ErbB4 Signaling",2.36,0.111,0,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["ErbB4 Signaling",2.36,0.111,0,"PSENEN","presenilin enhancer gamma secretase subunit","Plasma Membrane","peptidase",0.0017462111,0.00074735825,"up",1.374307,1.374307,0.45870435]
["ErbB4 Signaling",2.36,0.111,0,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["ErbB4 Signaling",2.36,0.111,0,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["ErbB4 Signaling",2.36,0.111,0,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["ErbB4 Signaling",2.36,0.111,0,"APH1B","aph-1 homolog B, gamma secretase subunit","Other","peptidase",0.0012306612,0.00029680028,"up",1.5021218,1.5021218,0.5870018]
["NRF2-mediated Oxidative Stress Response",2.35,0.0777,-0.816,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["NRF2-mediated Oxidative Stress Response",2.35,0.0777,-0.816,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["NRF2-mediated Oxidative Stress Response",2.35,0.0777,-0.816,"PRDX1","peroxiredoxin 1","Cytoplasm","enzyme",6.045441e-05,1.0414197e-07,"down",5.09895,-5.09895,-2.3502002]
["NRF2-mediated Oxidative Stress Response",2.35,0.0777,-0.816,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["NRF2-mediated Oxidative Stress Response",2.35,0.0777,-0.816,"DNAJC6","DnaJ heat shock protein family (Hsp40) member C6","Cytoplasm","other",0.00471877,0.0034019037,"up",1.5755986,1.5755986,0.6559]
["NRF2-mediated Oxidative Stress Response",2.35,0.0777,-0.816,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["NRF2-mediated Oxidative Stress Response",2.35,0.0777,-0.816,"GCLC","glutamate-cysteine ligase catalytic subunit","Cytoplasm","enzyme",0.001961328,0.0009667417,"down",1.3574277,-1.3574277,-0.44087538]
["NRF2-mediated Oxidative Stress Response",2.35,0.0777,-0.816,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["NRF2-mediated Oxidative Stress Response",2.35,0.0777,-0.816,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["NRF2-mediated Oxidative Stress Response",2.35,0.0777,-0.816,"GSTT2/GSTT2B","glutathione S-transferase theta 2 (gene/pseudogene)","Cytoplasm","enzyme",0.0011259156,0.00022387244,"up",1.4915317,1.4915317,0.5767947]
["NRF2-mediated Oxidative Stress Response",2.35,0.0777,-0.816,"FTL","ferritin, light polypeptide","Cytoplasm","enzyme",0.0011684936,0.0002475878,"down",1.3095047,-1.3095047,-0.38902128]
["NRF2-mediated Oxidative Stress Response",2.35,0.0777,-0.816,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["NRF2-mediated Oxidative Stress Response",2.35,0.0777,-0.816,"DNAJC18","DnaJ heat shock protein family (Hsp40) member C18","Other","enzyme",0.004395149,0.0030934683,"up",1.7337146,1.7337146,0.7938664]
["NRF2-mediated Oxidative Stress Response",2.35,0.0777,-0.816,"DNAJB6","DnaJ heat shock protein family (Hsp40) member B6","Nucleus","transcription regulator",0.0016760693,0.00068303355,"up",2.0961676,2.0961676,1.067754]
["NRF2-mediated Oxidative Stress Response",2.35,0.0777,-0.816,"DNAJB1","DnaJ heat shock protein family (Hsp40) member B1","Nucleus","other",0.0012010665,0.0002643174,"down",2.432129,-2.432129,-1.2822196]
["FGF Signaling",2.29,0.1,1.667,"MET","MET proto-oncogene, receptor tyrosine kinase","Plasma Membrane","kinase",0.0008691947,0.00010051858,"up",1.5833938,1.5833938,0.66302013]
["FGF Signaling",2.29,0.1,1.667,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["FGF Signaling",2.29,0.1,1.667,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["FGF Signaling",2.29,0.1,1.667,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["FGF Signaling",2.29,0.1,1.667,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["FGF Signaling",2.29,0.1,1.667,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["FGF Signaling",2.29,0.1,1.667,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["FGF Signaling",2.29,0.1,1.667,"ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["FGF Signaling",2.29,0.1,1.667,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["ATM Signaling",2.28,0.119,1.633,"GADD45B","growth arrest and DNA damage inducible beta","Cytoplasm","other",0.0013662435,0.00038785784,"up",1.6800824,1.6800824,0.748532]
["ATM Signaling",2.28,0.119,1.633,"CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["ATM Signaling",2.28,0.119,1.633,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["ATM Signaling",2.28,0.119,1.633,"CHEK2","checkpoint kinase 2","Nucleus","kinase",0.0028598784,0.0017272087,"up",1.3150214,1.3150214,0.39508626]
["ATM Signaling",2.28,0.119,1.633,"CHEK1","checkpoint kinase 1","Nucleus","kinase",0.0010877973,0.00019520131,"up",1.4226359,1.4226359,0.5085665]
["ATM Signaling",2.28,0.119,1.633,"SMC1A","structural maintenance of chromosomes 1A","Nucleus","transporter",0.0036513812,0.002431109,"up",1.3589398,1.3589398,0.44248152]
["ATM Signaling",2.28,0.119,1.633,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["Ephrin A Signaling",2.24,0.117,"NaN","ROCK2","Rho associated coiled-coil containing protein kinase 2","Cytoplasm","kinase",0.0010184328,0.00016622998,"up",1.3479002,1.3479002,0.43071362]
["Ephrin A Signaling",2.24,0.117,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Ephrin A Signaling",2.24,0.117,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Ephrin A Signaling",2.24,0.117,"NaN","CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["Ephrin A Signaling",2.24,0.117,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Ephrin A Signaling",2.24,0.117,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Ephrin A Signaling",2.24,0.117,"NaN","EFNA1","ephrin A1","Plasma Membrane","other",0.001983807,0.000985738,"up",1.3843216,1.3843216,0.4691791]
["Human Embryonic Stem Cell Pluripotency",2.24,0.0839,"NaN","SOX2","SRY-box 2","Nucleus","transcription regulator",0.0013107243,0.00034832067,"up",1.4385506,1.4385506,0.52461594]
["Human Embryonic Stem Cell Pluripotency",2.24,0.0839,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Human Embryonic Stem Cell Pluripotency",2.24,0.0839,"NaN","FZD10","frizzled class receptor 10","Plasma Membrane","G-protein coupled receptor",0.00084399927,9.184798e-05,"down",1.4670624,-1.4670624,-0.5529302]
["Human Embryonic Stem Cell Pluripotency",2.24,0.0839,"NaN","TGFBR1","transforming growth factor beta receptor 1","Plasma Membrane","kinase",0.0008942897,0.00011058827,"up",1.5758384,1.5758384,0.65611964]
["Human Embryonic Stem Cell Pluripotency",2.24,0.0839,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Human Embryonic Stem Cell Pluripotency",2.24,0.0839,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Human Embryonic Stem Cell Pluripotency",2.24,0.0839,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Human Embryonic Stem Cell Pluripotency",2.24,0.0839,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Human Embryonic Stem Cell Pluripotency",2.24,0.0839,"NaN","FZD5","frizzled class receptor 5","Plasma Membrane","G-protein coupled receptor",0.0011555209,0.00024123449,"down",1.5153433,-1.5153433,-0.59964466]
["Human Embryonic Stem Cell Pluripotency",2.24,0.0839,"NaN","FZD1","frizzled class receptor 1","Plasma Membrane","G-protein coupled receptor",0.0036817046,0.002460812,"down",1.529664,-1.529664,-0.6132148]
["Human Embryonic Stem Cell Pluripotency",2.24,0.0839,"NaN","SMAD5","SMAD family member 5","Nucleus","transcription regulator",0.0014749195,0.00048909907,"down",1.3112969,-1.3112969,-0.3909944]
["Human Embryonic Stem Cell Pluripotency",2.24,0.0839,"NaN","BMP6","bone morphogenetic protein 6","Extracellular Space","growth factor",0.0012361597,0.00030026503,"up",1.359715,1.359715,0.44330427]
["mTOR Signaling",2.23,0.0754,-1.508,"TSC1","tuberous sclerosis 1","Cytoplasm","other",0.0020370672,0.0010299383,"up",1.3084451,1.3084451,0.38785338]
["mTOR Signaling",2.23,0.0754,-1.508,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["mTOR Signaling",2.23,0.0754,-1.508,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["mTOR Signaling",2.23,0.0754,-1.508,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["mTOR Signaling",2.23,0.0754,-1.508,"EIF3J","eukaryotic translation initiation factor 3 subunit J","Cytoplasm","translation regulator",0.0008942897,0.00011461672,"down",1.5294574,-1.5294574,-0.61301994]
["mTOR Signaling",2.23,0.0754,-1.508,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["mTOR Signaling",2.23,0.0754,-1.508,"EIF3M","eukaryotic translation initiation factor 3 subunit M","Cytoplasm","other",0.0028598784,0.0017288154,"down",1.3275427,-1.3275427,-0.40875822]
["mTOR Signaling",2.23,0.0754,-1.508,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["mTOR Signaling",2.23,0.0754,-1.508,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["mTOR Signaling",2.23,0.0754,-1.508,"RHOU","ras homolog family member U","Cytoplasm","enzyme",0.0009194498,0.00012193339,"down",1.7715495,-1.7715495,-0.82501173]
["mTOR Signaling",2.23,0.0754,-1.508,"PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["mTOR Signaling",2.23,0.0754,-1.508,"PRKAA2","protein kinase AMP-activated catalytic subunit alpha 2","Cytoplasm","kinase",0.0014867174,0.0005054725,"up",1.3466656,1.3466656,0.42939165]
["mTOR Signaling",2.23,0.0754,-1.508,"RPS6KB2","ribosomal protein S6 kinase B2","Cytoplasm","kinase",0.0016431456,0.0006520507,"down",1.986918,-1.986918,-0.9905323]
["mTOR Signaling",2.23,0.0754,-1.508,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["mTOR Signaling",2.23,0.0754,-1.508,"RPS27A","ribosomal protein S27a","Cytoplasm","other",0.0033264575,0.002133116,"down",1.341015,-1.341015,-0.42332536]
["Reelin Signaling in Neurons",2.22,0.0978,"NaN","ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["Reelin Signaling in Neurons",2.22,0.0978,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Reelin Signaling in Neurons",2.22,0.0978,"NaN","NDEL1","nudE neurodevelopment protein 1 like 1","Nucleus","other",0.0029613294,0.001812252,"down",1.6251583,-1.6251583,-0.70058024]
["Reelin Signaling in Neurons",2.22,0.0978,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Reelin Signaling in Neurons",2.22,0.0978,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Reelin Signaling in Neurons",2.22,0.0978,"NaN","MAPK8IP2","mitogen-activated protein kinase 8 interacting protein 2","Cytoplasm","other",0.046502918,0.04538104,"up",1.3104981,1.3104981,0.3901153]
["Reelin Signaling in Neurons",2.22,0.0978,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Reelin Signaling in Neurons",2.22,0.0978,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Reelin Signaling in Neurons",2.22,0.0978,"NaN","PAFAH1B3","platelet activating factor acetylhydrolase 1b catalytic subunit 3","Cytoplasm","enzyme",0.0029175605,0.0017729017,"up",1.3077043,1.3077043,0.38703638]
["Factors Promoting Cardiogenesis in Vertebrates",2.22,0.0978,"NaN","FZD10","frizzled class receptor 10","Plasma Membrane","G-protein coupled receptor",0.00084399927,9.184798e-05,"down",1.4670624,-1.4670624,-0.5529302]
["Factors Promoting Cardiogenesis in Vertebrates",2.22,0.0978,"NaN","CCNE1","cyclin E1","Nucleus","transcription regulator",0.0013342145,0.00036659295,"down",2.6488216,-2.6488216,-1.4053507]
["Factors Promoting Cardiogenesis in Vertebrates",2.22,0.0978,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Factors Promoting Cardiogenesis in Vertebrates",2.22,0.0978,"NaN","TGFBR1","transforming growth factor beta receptor 1","Plasma Membrane","kinase",0.0008942897,0.00011058827,"up",1.5758384,1.5758384,0.65611964]
["Factors Promoting Cardiogenesis in Vertebrates",2.22,0.0978,"NaN","FZD5","frizzled class receptor 5","Plasma Membrane","G-protein coupled receptor",0.0011555209,0.00024123449,"down",1.5153433,-1.5153433,-0.59964466]
["Factors Promoting Cardiogenesis in Vertebrates",2.22,0.0978,"NaN","FZD1","frizzled class receptor 1","Plasma Membrane","G-protein coupled receptor",0.0036817046,0.002460812,"down",1.529664,-1.529664,-0.6132148]
["Factors Promoting Cardiogenesis in Vertebrates",2.22,0.0978,"NaN","SMAD5","SMAD family member 5","Nucleus","transcription regulator",0.0014749195,0.00048909907,"down",1.3112969,-1.3112969,-0.3909944]
["Factors Promoting Cardiogenesis in Vertebrates",2.22,0.0978,"NaN","BMP6","bone morphogenetic protein 6","Extracellular Space","growth factor",0.0012361597,0.00030026503,"up",1.359715,1.359715,0.44330427]
["Factors Promoting Cardiogenesis in Vertebrates",2.22,0.0978,"NaN","ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["GDNF Family Ligand-Receptor Interactions",2.22,0.105,0.378,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["GDNF Family Ligand-Receptor Interactions",2.22,0.105,0.378,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["GDNF Family Ligand-Receptor Interactions",2.22,0.105,0.378,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["GDNF Family Ligand-Receptor Interactions",2.22,0.105,0.378,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["GDNF Family Ligand-Receptor Interactions",2.22,0.105,0.378,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["GDNF Family Ligand-Receptor Interactions",2.22,0.105,0.378,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["GDNF Family Ligand-Receptor Interactions",2.22,0.105,0.378,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["GDNF Family Ligand-Receptor Interactions",2.22,0.105,0.378,"ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["Salvage Pathways of Pyrimidine Ribonucleotides",2.19,0.0968,"NaN","PRKX","protein kinase, X-linked","Cytoplasm","kinase",0.00055139343,1.662609e-05,"down",1.4422405,-1.4422405,-0.5283117]
["Salvage Pathways of Pyrimidine Ribonucleotides",2.19,0.0968,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Salvage Pathways of Pyrimidine Ribonucleotides",2.19,0.0968,"NaN","PRPF4B","pre-mRNA processing factor 4B","Nucleus","kinase",0.012723735,0.0113428645,"down",1.3757049,-1.3757049,-0.460171]
["Salvage Pathways of Pyrimidine Ribonucleotides",2.19,0.0968,"NaN","PRKAA2","protein kinase AMP-activated catalytic subunit alpha 2","Cytoplasm","kinase",0.0014867174,0.0005054725,"up",1.3466656,1.3466656,0.42939165]
["Salvage Pathways of Pyrimidine Ribonucleotides",2.19,0.0968,"NaN","CDK6","cyclin-dependent kinase 6","Nucleus","kinase",0.0011555209,0.0002428485,"down",1.6726129,-1.6726129,-0.7421036]
["Salvage Pathways of Pyrimidine Ribonucleotides",2.19,0.0968,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Salvage Pathways of Pyrimidine Ribonucleotides",2.19,0.0968,"NaN","CMPK1","cytidine/uridine monophosphate kinase 1","Nucleus","kinase",0.00036445798,4.4485446e-06,"down",3.5441682,-3.5441682,-1.8254471]
["Salvage Pathways of Pyrimidine Ribonucleotides",2.19,0.0968,"NaN","LIMK2","LIM domain kinase 2","Cytoplasm","kinase",0.0035328772,0.002318736,"up",1.3875531,1.3875531,0.47254297]
["Salvage Pathways of Pyrimidine Ribonucleotides",2.19,0.0968,"NaN","HIPK1","homeodomain interacting protein kinase 1","Nucleus","kinase",0.01500758,0.013656768,"down",1.3206239,-1.3206239,-0.40121964]
["Non-Small Cell Lung Cancer Signaling",2.19,0.104,1.134,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Non-Small Cell Lung Cancer Signaling",2.19,0.104,1.134,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Non-Small Cell Lung Cancer Signaling",2.19,0.104,1.134,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Non-Small Cell Lung Cancer Signaling",2.19,0.104,1.134,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Non-Small Cell Lung Cancer Signaling",2.19,0.104,1.134,"CDK6","cyclin-dependent kinase 6","Nucleus","kinase",0.0011555209,0.0002428485,"down",1.6726129,-1.6726129,-0.7421036]
["Non-Small Cell Lung Cancer Signaling",2.19,0.104,1.134,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Non-Small Cell Lung Cancer Signaling",2.19,0.104,1.134,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Non-Small Cell Lung Cancer Signaling",2.19,0.104,1.134,"ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["Melanocyte Development and Pigmentation Signaling",2.13,0.0947,1,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Melanocyte Development and Pigmentation Signaling",2.13,0.0947,1,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Melanocyte Development and Pigmentation Signaling",2.13,0.0947,1,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Melanocyte Development and Pigmentation Signaling",2.13,0.0947,1,"MITF","microphthalmia-associated transcription factor","Nucleus","transcription regulator",0.0009366118,0.00012626672,"up",1.3044807,1.3044807,0.38347557]
["Melanocyte Development and Pigmentation Signaling",2.13,0.0947,1,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Melanocyte Development and Pigmentation Signaling",2.13,0.0947,1,"RPS6KB2","ribosomal protein S6 kinase B2","Cytoplasm","kinase",0.0016431456,0.0006520507,"down",1.986918,-1.986918,-0.9905323]
["Melanocyte Development and Pigmentation Signaling",2.13,0.0947,1,"PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Melanocyte Development and Pigmentation Signaling",2.13,0.0947,1,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Melanocyte Development and Pigmentation Signaling",2.13,0.0947,1,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["CNTF Signaling",2.13,0.111,0.378,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["CNTF Signaling",2.13,0.111,0.378,"LIFR","leukemia inhibitory factor receptor alpha","Plasma Membrane","transmembrane receptor",0.001213793,0.00026979306,"up",1.903933,1.903933,0.92898273]
["CNTF Signaling",2.13,0.111,0.378,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["CNTF Signaling",2.13,0.111,0.378,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["CNTF Signaling",2.13,0.111,0.378,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["CNTF Signaling",2.13,0.111,0.378,"RPS6KB2","ribosomal protein S6 kinase B2","Cytoplasm","kinase",0.0016431456,0.0006520507,"down",1.986918,-1.986918,-0.9905323]
["CNTF Signaling",2.13,0.111,0.378,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["14-3-3-mediated Signaling",2.12,0.0846,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["14-3-3-mediated Signaling",2.12,0.0846,"NaN","TSC1","tuberous sclerosis 1","Cytoplasm","other",0.0020370672,0.0010299383,"up",1.3084451,1.3084451,0.38785338]
["14-3-3-mediated Signaling",2.12,0.0846,"NaN","TUBB3","tubulin beta 3 class III","Cytoplasm","other",0.001459056,0.00047059942,"up",1.4351482,1.4351482,0.52119976]
["14-3-3-mediated Signaling",2.12,0.0846,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["14-3-3-mediated Signaling",2.12,0.0846,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["14-3-3-mediated Signaling",2.12,0.0846,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["14-3-3-mediated Signaling",2.12,0.0846,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["14-3-3-mediated Signaling",2.12,0.0846,"NaN","TUBB2A","tubulin beta 2A class IIa","Cytoplasm","other",0.0026605518,0.0015617278,"up",1.4475315,1.4475315,0.5335947]
["14-3-3-mediated Signaling",2.12,0.0846,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["14-3-3-mediated Signaling",2.12,0.0846,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["14-3-3-mediated Signaling",2.12,0.0846,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Tight Junction Signaling",2.11,0.0778,"NaN","TGFBR1","transforming growth factor beta receptor 1","Plasma Membrane","kinase",0.0008942897,0.00011058827,"up",1.5758384,1.5758384,0.65611964]
["Tight Junction Signaling",2.11,0.0778,"NaN","MLLT4","myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4","Nucleus","other",0.0013056329,0.00034460775,"up",1.7435131,1.7435131,0.8019972]
["Tight Junction Signaling",2.11,0.0778,"NaN","MYL6B","myosin light chain 6B","Cytoplasm","other",0.0037700427,0.0025393397,"up",1.3426967,1.3426967,0.4251334]
["Tight Junction Signaling",2.11,0.0778,"NaN","CNKSR3","CNKSR family member 3","Plasma Membrane","kinase",0.0006943628,4.4579963e-05,"down",2.208642,-2.208642,-1.1431596]
["Tight Junction Signaling",2.11,0.0778,"NaN","SNAP25","synaptosome associated protein 25kDa","Plasma Membrane","transporter",0.001213793,0.00027191787,"up",2.3686213,2.3686213,1.2440475]
["Tight Junction Signaling",2.11,0.0778,"NaN","PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["Tight Junction Signaling",2.11,0.0778,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Tight Junction Signaling",2.11,0.0778,"NaN","CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["Tight Junction Signaling",2.11,0.0778,"NaN","CGN","cingulin","Plasma Membrane","other",0.0016183598,0.0006279682,"up",1.3458213,1.3458213,0.42848682]
["Tight Junction Signaling",2.11,0.0778,"NaN","PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Tight Junction Signaling",2.11,0.0778,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Tight Junction Signaling",2.11,0.0778,"NaN","PATJ","PATJ, crumbs cell polarity complex component","Plasma Membrane","other",0.012302879,0.010879122,"up",1.3560606,1.3560606,0.43942168]
["Tight Junction Signaling",2.11,0.0778,"NaN","NECTIN2","nectin cell adhesion molecule 2","Plasma Membrane","transmembrane receptor",0.0023623689,0.0013073402,"up",1.3960435,1.3960435,0.48134392]
["Growth Hormone Signaling",2.06,0.0988,-0.378,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Growth Hormone Signaling",2.06,0.0988,-0.378,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Growth Hormone Signaling",2.06,0.0988,-0.378,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Growth Hormone Signaling",2.06,0.0988,-0.378,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Growth Hormone Signaling",2.06,0.0988,-0.378,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Growth Hormone Signaling",2.06,0.0988,-0.378,"IGF1R","insulin like growth factor 1 receptor","Plasma Membrane","transmembrane receptor",0.0016147236,0.0006161828,"up",1.8701973,1.8701973,0.90319043]
["Growth Hormone Signaling",2.06,0.0988,-0.378,"RPS6KB2","ribosomal protein S6 kinase B2","Cytoplasm","kinase",0.0016431456,0.0006520507,"down",1.986918,-1.986918,-0.9905323]
["Growth Hormone Signaling",2.06,0.0988,-0.378,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["HMGB1 Signaling",2.05,0.0827,0,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["HMGB1 Signaling",2.05,0.0827,0,"CXCL8","C-X-C motif chemokine ligand 8","Extracellular Space","cytokine",0.0011259156,0.00022286079,"down",1.5851029,-1.5851029,-0.66457653]
["HMGB1 Signaling",2.05,0.0827,0,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["HMGB1 Signaling",2.05,0.0827,0,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["HMGB1 Signaling",2.05,0.0827,0,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["HMGB1 Signaling",2.05,0.0827,0,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["HMGB1 Signaling",2.05,0.0827,0,"RHOU","ras homolog family member U","Cytoplasm","enzyme",0.0009194498,0.00012193339,"down",1.7715495,-1.7715495,-0.82501173]
["HMGB1 Signaling",2.05,0.0827,0,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["HMGB1 Signaling",2.05,0.0827,0,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["HMGB1 Signaling",2.05,0.0827,0,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["HMGB1 Signaling",2.05,0.0827,0,"SERPINE1","serpin family E member 1","Extracellular Space","other",0.0016010772,0.00060374127,"up",1.3806411,1.3806411,0.46533832]
["UVB-Induced MAPK Signaling",2.02,0.106,0.378,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["UVB-Induced MAPK Signaling",2.02,0.106,0.378,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["UVB-Induced MAPK Signaling",2.02,0.106,0.378,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["UVB-Induced MAPK Signaling",2.02,0.106,0.378,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["UVB-Induced MAPK Signaling",2.02,0.106,0.378,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["UVB-Induced MAPK Signaling",2.02,0.106,0.378,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["UVB-Induced MAPK Signaling",2.02,0.106,0.378,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["JAK/Stat Signaling",1.99,0.0964,0.707,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["JAK/Stat Signaling",1.99,0.0964,0.707,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["JAK/Stat Signaling",1.99,0.0964,0.707,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["JAK/Stat Signaling",1.99,0.0964,0.707,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["JAK/Stat Signaling",1.99,0.0964,0.707,"CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["JAK/Stat Signaling",1.99,0.0964,0.707,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["JAK/Stat Signaling",1.99,0.0964,0.707,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["JAK/Stat Signaling",1.99,0.0964,0.707,"CEBPB","CCAAT/enhancer binding protein beta","Nucleus","transcription regulator",0.021593252,0.020254135,"down",1.3026826,-1.3026826,-0.38148564]
["Lymphotoxin β Receptor Signaling",1.99,0.104,1.134,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Lymphotoxin β Receptor Signaling",1.99,0.104,1.134,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["Lymphotoxin β Receptor Signaling",1.99,0.104,1.134,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Lymphotoxin β Receptor Signaling",1.99,0.104,1.134,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Lymphotoxin β Receptor Signaling",1.99,0.104,1.134,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Lymphotoxin β Receptor Signaling",1.99,0.104,1.134,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Lymphotoxin β Receptor Signaling",1.99,0.104,1.134,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Ephrin Receptor Signaling",1.97,0.0747,0.905,"ROCK2","Rho associated coiled-coil containing protein kinase 2","Cytoplasm","kinase",0.0010184328,0.00016622998,"up",1.3479002,1.3479002,0.43071362]
["Ephrin Receptor Signaling",1.97,0.0747,0.905,"GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["Ephrin Receptor Signaling",1.97,0.0747,0.905,"ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["Ephrin Receptor Signaling",1.97,0.0747,0.905,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Ephrin Receptor Signaling",1.97,0.0747,0.905,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["Ephrin Receptor Signaling",1.97,0.0747,0.905,"SDC2","syndecan 2","Plasma Membrane","other",0.00067191356,4.108484e-05,"up",1.8298745,1.8298745,0.8717447]
["Ephrin Receptor Signaling",1.97,0.0747,0.905,"CXCR4","C-X-C motif chemokine receptor 4","Plasma Membrane","G-protein coupled receptor",0.0018305046,0.00083504117,"down",1.3248457,-1.3248457,-0.4058243]
["Ephrin Receptor Signaling",1.97,0.0747,0.905,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Ephrin Receptor Signaling",1.97,0.0747,0.905,"WASL","Wiskott-Aldrich syndrome like","Cytoplasm","other",0.00040977335,6.54692e-06,"up",1.4019742,1.4019742,0.4874598]
["Ephrin Receptor Signaling",1.97,0.0747,0.905,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Ephrin Receptor Signaling",1.97,0.0747,0.905,"LIMK2","LIM domain kinase 2","Cytoplasm","kinase",0.0035328772,0.002318736,"up",1.3875531,1.3875531,0.47254297]
["Ephrin Receptor Signaling",1.97,0.0747,0.905,"EFNA1","ephrin A1","Plasma Membrane","other",0.001983807,0.000985738,"up",1.3843216,1.3843216,0.4691791]
["Ephrin Receptor Signaling",1.97,0.0747,0.905,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["Docosahexaenoic Acid (DHA) Signaling",1.97,0.115,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Docosahexaenoic Acid (DHA) Signaling",1.97,0.115,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Docosahexaenoic Acid (DHA) Signaling",1.97,0.115,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Docosahexaenoic Acid (DHA) Signaling",1.97,0.115,"NaN","BIK","BCL2 interacting killer","Cytoplasm","other",0.0014867174,0.00050706835,"up",1.5836127,1.5836127,0.6632195]
["Docosahexaenoic Acid (DHA) Signaling",1.97,0.115,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Docosahexaenoic Acid (DHA) Signaling",1.97,0.115,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["RANK Signaling in Osteoclasts",1.97,0.0891,1.667,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["RANK Signaling in Osteoclasts",1.97,0.0891,1.667,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["RANK Signaling in Osteoclasts",1.97,0.0891,1.667,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["RANK Signaling in Osteoclasts",1.97,0.0891,1.667,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["RANK Signaling in Osteoclasts",1.97,0.0891,1.667,"MITF","microphthalmia-associated transcription factor","Nucleus","transcription regulator",0.0009366118,0.00012626672,"up",1.3044807,1.3044807,0.38347557]
["RANK Signaling in Osteoclasts",1.97,0.0891,1.667,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["RANK Signaling in Osteoclasts",1.97,0.0891,1.667,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["RANK Signaling in Osteoclasts",1.97,0.0891,1.667,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["RANK Signaling in Osteoclasts",1.97,0.0891,1.667,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["PEDF Signaling",1.96,0.0952,0.707,"ROCK2","Rho associated coiled-coil containing protein kinase 2","Cytoplasm","kinase",0.0010184328,0.00016622998,"up",1.3479002,1.3479002,0.43071362]
["PEDF Signaling",1.96,0.0952,0.707,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["PEDF Signaling",1.96,0.0952,0.707,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["PEDF Signaling",1.96,0.0952,0.707,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["PEDF Signaling",1.96,0.0952,0.707,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["PEDF Signaling",1.96,0.0952,0.707,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["PEDF Signaling",1.96,0.0952,0.707,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["PEDF Signaling",1.96,0.0952,0.707,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["EGF Signaling",1.95,0.103,1.134,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["EGF Signaling",1.95,0.103,1.134,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["EGF Signaling",1.95,0.103,1.134,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["EGF Signaling",1.95,0.103,1.134,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["EGF Signaling",1.95,0.103,1.134,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["EGF Signaling",1.95,0.103,1.134,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["EGF Signaling",1.95,0.103,1.134,"ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["Cardiac Hypertrophy Signaling",1.94,0.0681,1.291,"GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["Cardiac Hypertrophy Signaling",1.94,0.0681,1.291,"TGFBR1","transforming growth factor beta receptor 1","Plasma Membrane","kinase",0.0008942897,0.00011058827,"up",1.5758384,1.5758384,0.65611964]
["Cardiac Hypertrophy Signaling",1.94,0.0681,1.291,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Cardiac Hypertrophy Signaling",1.94,0.0681,1.291,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Cardiac Hypertrophy Signaling",1.94,0.0681,1.291,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Cardiac Hypertrophy Signaling",1.94,0.0681,1.291,"MEF2A","myocyte enhancer factor 2A","Nucleus","transcription regulator",0.015937602,0.014585446,"down",1.3274704,-1.3274704,-0.40867972]
["Cardiac Hypertrophy Signaling",1.94,0.0681,1.291,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Cardiac Hypertrophy Signaling",1.94,0.0681,1.291,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Cardiac Hypertrophy Signaling",1.94,0.0681,1.291,"MYL6B","myosin light chain 6B","Cytoplasm","other",0.0037700427,0.0025393397,"up",1.3426967,1.3426967,0.4251334]
["Cardiac Hypertrophy Signaling",1.94,0.0681,1.291,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["Cardiac Hypertrophy Signaling",1.94,0.0681,1.291,"ROCK2","Rho associated coiled-coil containing protein kinase 2","Cytoplasm","kinase",0.0010184328,0.00016622998,"up",1.3479002,1.3479002,0.43071362]
["Cardiac Hypertrophy Signaling",1.94,0.0681,1.291,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Cardiac Hypertrophy Signaling",1.94,0.0681,1.291,"MEF2D","myocyte enhancer factor 2D","Nucleus","transcription regulator",0.0006217929,3.203251e-05,"down",1.3555743,-1.3555743,-0.43890414]
["Cardiac Hypertrophy Signaling",1.94,0.0681,1.291,"RHOU","ras homolog family member U","Cytoplasm","enzyme",0.0009194498,0.00012193339,"down",1.7715495,-1.7715495,-0.82501173]
["Cardiac Hypertrophy Signaling",1.94,0.0681,1.291,"IGF1R","insulin like growth factor 1 receptor","Plasma Membrane","transmembrane receptor",0.0016147236,0.0006161828,"up",1.8701973,1.8701973,0.90319043]
["Cardiac Hypertrophy Signaling",1.94,0.0681,1.291,"PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["FLT3 Signaling in Hematopoietic Progenitor Cells",1.93,0.0941,0.707,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["FLT3 Signaling in Hematopoietic Progenitor Cells",1.93,0.0941,0.707,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["FLT3 Signaling in Hematopoietic Progenitor Cells",1.93,0.0941,0.707,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["FLT3 Signaling in Hematopoietic Progenitor Cells",1.93,0.0941,0.707,"FLT3LG","fms related tyrosine kinase 3 ligand","Extracellular Space","cytokine",0.03553473,0.034377225,"down",1.3344398,-1.3344398,-0.41623417]
["FLT3 Signaling in Hematopoietic Progenitor Cells",1.93,0.0941,0.707,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["FLT3 Signaling in Hematopoietic Progenitor Cells",1.93,0.0941,0.707,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["FLT3 Signaling in Hematopoietic Progenitor Cells",1.93,0.0941,0.707,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["FLT3 Signaling in Hematopoietic Progenitor Cells",1.93,0.0941,0.707,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["Leptin Signaling in Obesity",1.93,0.0941,1.134,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Leptin Signaling in Obesity",1.93,0.0941,1.134,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Leptin Signaling in Obesity",1.93,0.0941,1.134,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Leptin Signaling in Obesity",1.93,0.0941,1.134,"PDE3B","phosphodiesterase 3B","Cytoplasm","enzyme",0.0026252405,0.0015308249,"up",1.3255126,1.3255126,0.40655044]
["Leptin Signaling in Obesity",1.93,0.0941,1.134,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Leptin Signaling in Obesity",1.93,0.0941,1.134,"PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Leptin Signaling in Obesity",1.93,0.0941,1.134,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Leptin Signaling in Obesity",1.93,0.0941,1.134,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Superpathway of D-myo-inositol (1,4,5)-trisphosphate Metabolism",1.93,0.16,"NaN","BPNT1","3'(2'), 5'-bisphosphate nucleotidase 1","Nucleus","phosphatase",0.0014996352,0.000517316,"down",2.1743834,-2.1743834,-1.1206063]
["Superpathway of D-myo-inositol (1,4,5)-trisphosphate Metabolism",1.93,0.16,"NaN","IMPA2","inositol monophosphatase 2","Cytoplasm","phosphatase",0.00084399927,9.163144e-05,"down",1.303337,-1.303337,-0.38221014]
["Superpathway of D-myo-inositol (1,4,5)-trisphosphate Metabolism",1.93,0.16,"NaN","INPP5A","inositol polyphosphate-5-phosphatase A","Plasma Membrane","phosphatase",0.0017193076,0.00071636395,"up",1.6724749,1.6724749,0.7419845]
["Superpathway of D-myo-inositol (1,4,5)-trisphosphate Metabolism",1.93,0.16,"NaN","PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["Renin-Angiotensin Signaling",1.93,0.0833,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Renin-Angiotensin Signaling",1.93,0.0833,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Renin-Angiotensin Signaling",1.93,0.0833,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Renin-Angiotensin Signaling",1.93,0.0833,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Renin-Angiotensin Signaling",1.93,0.0833,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Renin-Angiotensin Signaling",1.93,0.0833,"NaN","PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Renin-Angiotensin Signaling",1.93,0.0833,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Renin-Angiotensin Signaling",1.93,0.0833,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Renin-Angiotensin Signaling",1.93,0.0833,"NaN","ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["Renin-Angiotensin Signaling",1.93,0.0833,"NaN","ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["dTMP De Novo Biosynthesis",1.92,0.4,"NaN","SHMT1","serine hydroxymethyltransferase 1","Cytoplasm","enzyme",0.0008942897,0.000111482994,"up",1.4391686,1.4391686,0.5252356]
["dTMP De Novo Biosynthesis",1.92,0.4,"NaN","SHMT2","serine hydroxymethyltransferase 2","Cytoplasm","enzyme",0.0022647758,0.0012213683,"down",1.6496395,-1.6496395,-0.72215074]
["Folate Polyglutamylation",1.92,0.4,"NaN","SHMT1","serine hydroxymethyltransferase 1","Cytoplasm","enzyme",0.0008942897,0.000111482994,"up",1.4391686,1.4391686,0.5252356]
["Folate Polyglutamylation",1.92,0.4,"NaN","SHMT2","serine hydroxymethyltransferase 2","Cytoplasm","enzyme",0.0022647758,0.0012213683,"down",1.6496395,-1.6496395,-0.72215074]
["Calcium Signaling",1.9,0.073,0.378,"RAP2B","RAP2B, member of RAS oncogene family","Plasma Membrane","enzyme",0.0005464768,1.2239901e-05,"down",1.9869581,-1.9869581,-0.9905615]
["Calcium Signaling",1.9,0.073,0.378,"HDAC6","histone deacetylase 6","Nucleus","transcription regulator",0.0060592825,0.0047327504,"up",1.6543902,1.6543902,0.7262995]
["Calcium Signaling",1.9,0.073,0.378,"TNNT1","troponin T1, slow skeletal type","Cytoplasm","other",0.00070557836,5.5718752e-05,"up",1.4513307,1.4513307,0.5373762]
["Calcium Signaling",1.9,0.073,0.378,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Calcium Signaling",1.9,0.073,0.378,"ATP2C1","ATPase secretory pathway Ca2+ transporting 1","Cytoplasm","transporter",0.0045107757,0.0032051865,"up",1.313763,1.313763,0.39370507]
["Calcium Signaling",1.9,0.073,0.378,"MEF2D","myocyte enhancer factor 2D","Nucleus","transcription regulator",0.0006217929,3.203251e-05,"down",1.3555743,-1.3555743,-0.43890414]
["Calcium Signaling",1.9,0.073,0.378,"TNNT2","troponin T2, cardiac type","Cytoplasm","other",0.0037018578,0.0024846059,"up",1.750047,1.750047,0.8073936]
["Calcium Signaling",1.9,0.073,0.378,"MEF2A","myocyte enhancer factor 2A","Nucleus","transcription regulator",0.015937602,0.014585446,"down",1.3274704,-1.3274704,-0.40867972]
["Calcium Signaling",1.9,0.073,0.378,"PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Calcium Signaling",1.9,0.073,0.378,"RCAN3","RCAN family member 3","Other","other",0.0008613762,9.7631746e-05,"up",1.423743,1.423743,0.50968874]
["Calcium Signaling",1.9,0.073,0.378,"MYL6B","myosin light chain 6B","Cytoplasm","other",0.0037700427,0.0025393397,"up",1.3426967,1.3426967,0.4251334]
["Calcium Signaling",1.9,0.073,0.378,"ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["Calcium Signaling",1.9,0.073,0.378,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["Aryl Hydrocarbon Receptor Signaling",1.9,0.0786,-1,"TGM2","transglutaminase 2","Cytoplasm","enzyme",0.0012591777,0.00031366711,"down",1.4611537,-1.4611537,-0.547108]
["Aryl Hydrocarbon Receptor Signaling",1.9,0.0786,-1,"GSTT2/GSTT2B","glutathione S-transferase theta 2 (gene/pseudogene)","Cytoplasm","enzyme",0.0011259156,0.00022387244,"up",1.4915317,1.4915317,0.5767947]
["Aryl Hydrocarbon Receptor Signaling",1.9,0.0786,-1,"CCNE1","cyclin E1","Nucleus","transcription regulator",0.0013342145,0.00036659295,"down",2.6488216,-2.6488216,-1.4053507]
["Aryl Hydrocarbon Receptor Signaling",1.9,0.0786,-1,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Aryl Hydrocarbon Receptor Signaling",1.9,0.0786,-1,"MED1","mediator complex subunit 1","Nucleus","transcription regulator",0.007830824,0.006407651,"down",1.3726159,-1.3726159,-0.456928]
["Aryl Hydrocarbon Receptor Signaling",1.9,0.0786,-1,"NFIA","nuclear factor I A","Nucleus","transcription regulator",0.0014295598,0.00044332872,"up",1.3992724,1.3992724,0.48467687]
["Aryl Hydrocarbon Receptor Signaling",1.9,0.0786,-1,"CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["Aryl Hydrocarbon Receptor Signaling",1.9,0.0786,-1,"CDK6","cyclin-dependent kinase 6","Nucleus","kinase",0.0011555209,0.0002428485,"down",1.6726129,-1.6726129,-0.7421036]
["Aryl Hydrocarbon Receptor Signaling",1.9,0.0786,-1,"HSP90AA1","heat shock protein 90kDa alpha family class A member 1","Cytoplasm","enzyme",0.0005783946,2.0937947e-05,"up",1.5556576,1.5556576,0.63752455]
["Aryl Hydrocarbon Receptor Signaling",1.9,0.0786,-1,"CHEK2","checkpoint kinase 2","Nucleus","kinase",0.0028598784,0.0017272087,"up",1.3150214,1.3150214,0.39508626]
["Aryl Hydrocarbon Receptor Signaling",1.9,0.0786,-1,"CHEK1","checkpoint kinase 1","Nucleus","kinase",0.0010877973,0.00019520131,"up",1.4226359,1.4226359,0.5085665]
["SAPK/JNK Signaling",1.89,0.0865,0.707,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["SAPK/JNK Signaling",1.89,0.0865,0.707,"TRADD","TNFRSF1A associated via death domain","Cytoplasm","other",0.0016301863,0.0006398275,"up",1.3732907,1.3732907,0.457637]
["SAPK/JNK Signaling",1.89,0.0865,0.707,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["SAPK/JNK Signaling",1.89,0.0865,0.707,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["SAPK/JNK Signaling",1.89,0.0865,0.707,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["SAPK/JNK Signaling",1.89,0.0865,0.707,"MAPK8IP2","mitogen-activated protein kinase 8 interacting protein 2","Cytoplasm","other",0.046502918,0.04538104,"up",1.3104981,1.3104981,0.3901153]
["SAPK/JNK Signaling",1.89,0.0865,0.707,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["SAPK/JNK Signaling",1.89,0.0865,0.707,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["SAPK/JNK Signaling",1.89,0.0865,0.707,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["Sphingosine-1-phosphate Signaling",1.89,0.082,1,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Sphingosine-1-phosphate Signaling",1.89,0.082,1,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Sphingosine-1-phosphate Signaling",1.89,0.082,1,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Sphingosine-1-phosphate Signaling",1.89,0.082,1,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Sphingosine-1-phosphate Signaling",1.89,0.082,1,"CASP2","caspase 2","Cytoplasm","peptidase",0.0015242294,0.0005334935,"down",1.3856739,-1.3856739,-0.47058776]
["Sphingosine-1-phosphate Signaling",1.89,0.082,1,"CASP1","caspase 1","Cytoplasm","peptidase",0.0010976536,0.00020770791,"down",1.8456633,-1.8456633,-0.88413936]
["Sphingosine-1-phosphate Signaling",1.89,0.082,1,"RHOU","ras homolog family member U","Cytoplasm","enzyme",0.0009194498,0.00012193339,"down",1.7715495,-1.7715495,-0.82501173]
["Sphingosine-1-phosphate Signaling",1.89,0.082,1,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Sphingosine-1-phosphate Signaling",1.89,0.082,1,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Sphingosine-1-phosphate Signaling",1.89,0.082,1,"ASAH1","N-acylsphingosine amidohydrolase (acid ceramidase) 1","Cytoplasm","enzyme",0.007317322,0.0059212954,"down",1.4117956,-1.4117956,-0.49753124]
["Myc Mediated Apoptosis Signaling",1.89,0.1,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Myc Mediated Apoptosis Signaling",1.89,0.1,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Myc Mediated Apoptosis Signaling",1.89,0.1,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Myc Mediated Apoptosis Signaling",1.89,0.1,"NaN","IGF1R","insulin like growth factor 1 receptor","Plasma Membrane","transmembrane receptor",0.0016147236,0.0006161828,"up",1.8701973,1.8701973,0.90319043]
["Myc Mediated Apoptosis Signaling",1.89,0.1,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Myc Mediated Apoptosis Signaling",1.89,0.1,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Myc Mediated Apoptosis Signaling",1.89,0.1,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Gαq Signaling",1.87,0.075,0.905,"ROCK2","Rho associated coiled-coil containing protein kinase 2","Cytoplasm","kinase",0.0010184328,0.00016622998,"up",1.3479002,1.3479002,0.43071362]
["Gαq Signaling",1.87,0.075,0.905,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Gαq Signaling",1.87,0.075,0.905,"GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["Gαq Signaling",1.87,0.075,0.905,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["Gαq Signaling",1.87,0.075,0.905,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Gαq Signaling",1.87,0.075,0.905,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Gαq Signaling",1.87,0.075,0.905,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Gαq Signaling",1.87,0.075,0.905,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Gαq Signaling",1.87,0.075,0.905,"RHOU","ras homolog family member U","Cytoplasm","enzyme",0.0009194498,0.00012193339,"down",1.7715495,-1.7715495,-0.82501173]
["Gαq Signaling",1.87,0.075,0.905,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Gαq Signaling",1.87,0.075,0.905,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Gαq Signaling",1.87,0.075,0.905,"ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["G Beta Gamma Signaling",1.85,0.0909,0.707,"GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["G Beta Gamma Signaling",1.85,0.0909,0.707,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["G Beta Gamma Signaling",1.85,0.0909,0.707,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["G Beta Gamma Signaling",1.85,0.0909,0.707,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["G Beta Gamma Signaling",1.85,0.0909,0.707,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["G Beta Gamma Signaling",1.85,0.0909,0.707,"CAV1","caveolin 1","Plasma Membrane","transmembrane receptor",0.0014512807,0.00046188477,"up",1.5792397,1.5792397,0.6592302]
["G Beta Gamma Signaling",1.85,0.0909,0.707,"PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["G Beta Gamma Signaling",1.85,0.0909,0.707,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Actin Nucleation by ARP-WASP Complex",1.82,0.107,-0.447,"ROCK2","Rho associated coiled-coil containing protein kinase 2","Cytoplasm","kinase",0.0010184328,0.00016622998,"up",1.3479002,1.3479002,0.43071362]
["Actin Nucleation by ARP-WASP Complex",1.82,0.107,-0.447,"ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["Actin Nucleation by ARP-WASP Complex",1.82,0.107,-0.447,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Actin Nucleation by ARP-WASP Complex",1.82,0.107,-0.447,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["Actin Nucleation by ARP-WASP Complex",1.82,0.107,-0.447,"WASL","Wiskott-Aldrich syndrome like","Cytoplasm","other",0.00040977335,6.54692e-06,"up",1.4019742,1.4019742,0.4874598]
["Actin Nucleation by ARP-WASP Complex",1.82,0.107,-0.447,"RHOU","ras homolog family member U","Cytoplasm","enzyme",0.0009194498,0.00012193339,"down",1.7715495,-1.7715495,-0.82501173]
["Role of NFAT in Regulation of the Immune Response",1.8,0.071,0.302,"GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["Role of NFAT in Regulation of the Immune Response",1.8,0.071,0.302,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Role of NFAT in Regulation of the Immune Response",1.8,0.071,0.302,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Role of NFAT in Regulation of the Immune Response",1.8,0.071,0.302,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Role of NFAT in Regulation of the Immune Response",1.8,0.071,0.302,"MEF2A","myocyte enhancer factor 2A","Nucleus","transcription regulator",0.015937602,0.014585446,"down",1.3274704,-1.3274704,-0.40867972]
["Role of NFAT in Regulation of the Immune Response",1.8,0.071,0.302,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Role of NFAT in Regulation of the Immune Response",1.8,0.071,0.302,"ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["Role of NFAT in Regulation of the Immune Response",1.8,0.071,0.302,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["Role of NFAT in Regulation of the Immune Response",1.8,0.071,0.302,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Role of NFAT in Regulation of the Immune Response",1.8,0.071,0.302,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["Role of NFAT in Regulation of the Immune Response",1.8,0.071,0.302,"MEF2D","myocyte enhancer factor 2D","Nucleus","transcription regulator",0.0006217929,3.203251e-05,"down",1.3555743,-1.3555743,-0.43890414]
["Role of NFAT in Regulation of the Immune Response",1.8,0.071,0.302,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Role of NFAT in Regulation of the Immune Response",1.8,0.071,0.302,"RCAN3","RCAN family member 3","Other","other",0.0008613762,9.7631746e-05,"up",1.423743,1.423743,0.50968874]
["STAT3 Pathway",1.79,0.0959,2.646,"TGFBR1","transforming growth factor beta receptor 1","Plasma Membrane","kinase",0.0008942897,0.00011058827,"up",1.5758384,1.5758384,0.65611964]
["STAT3 Pathway",1.79,0.0959,2.646,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["STAT3 Pathway",1.79,0.0959,2.646,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["STAT3 Pathway",1.79,0.0959,2.646,"CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["STAT3 Pathway",1.79,0.0959,2.646,"IGF1R","insulin like growth factor 1 receptor","Plasma Membrane","transmembrane receptor",0.0016147236,0.0006161828,"up",1.8701973,1.8701973,0.90319043]
["STAT3 Pathway",1.79,0.0959,2.646,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["STAT3 Pathway",1.79,0.0959,2.646,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["3-phosphoinositide Biosynthesis",1.79,0.0707,"NaN","MTMR9","myotubularin related protein 9","Cytoplasm","phosphatase",0.0011428653,0.0002310908,"down",1.3561463,-1.3561463,-0.43951285]
["3-phosphoinositide Biosynthesis",1.79,0.0707,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["3-phosphoinositide Biosynthesis",1.79,0.0707,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["3-phosphoinositide Biosynthesis",1.79,0.0707,"NaN","NUDT12","nudix hydrolase 12","Cytoplasm","phosphatase",0.0015242294,0.00053365715,"up",1.4112375,1.4112375,0.49696076]
["3-phosphoinositide Biosynthesis",1.79,0.0707,"NaN","PPFIA3","PTPRF interacting protein alpha 3","Plasma Membrane","phosphatase",0.0022608375,0.0012176248,"up",1.4032409,1.4032409,0.4887627]
["3-phosphoinositide Biosynthesis",1.79,0.0707,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["3-phosphoinositide Biosynthesis",1.79,0.0707,"NaN","STYX","serine/threonine/tyrosine interacting protein","Cytoplasm","phosphatase",0.0006217929,2.9874785e-05,"up",1.4957032,1.4957032,0.58082396]
["3-phosphoinositide Biosynthesis",1.79,0.0707,"NaN","STYXL1","serine/threonine/tyrosine interacting-like 1","Cytoplasm","phosphatase",0.0017035499,0.00070178014,"up",1.310616,1.310616,0.39024505]
["3-phosphoinositide Biosynthesis",1.79,0.0707,"NaN","PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["3-phosphoinositide Biosynthesis",1.79,0.0707,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["3-phosphoinositide Biosynthesis",1.79,0.0707,"NaN","PPM1H","protein phosphatase, Mg2+/Mn2+ dependent 1H","Other","phosphatase",0.001395873,0.00041960352,"up",1.558836,1.558836,0.64046913]
["3-phosphoinositide Biosynthesis",1.79,0.0707,"NaN","MTMR2","myotubularin related protein 2","Cytoplasm","phosphatase",0.001395873,0.000419132,"up",1.3830658,1.3830658,0.46786982]
["3-phosphoinositide Biosynthesis",1.79,0.0707,"NaN","PPM1F","protein phosphatase, Mg2+/Mn2+ dependent 1F","Cytoplasm","phosphatase",0.0016241793,0.0006365216,"down",1.3318694,-1.3318694,-0.41345257]
["IL-6 Signaling",1.77,0.0787,0.632,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["IL-6 Signaling",1.77,0.0787,0.632,"CXCL8","C-X-C motif chemokine ligand 8","Extracellular Space","cytokine",0.0011259156,0.00022286079,"down",1.5851029,-1.5851029,-0.66457653]
["IL-6 Signaling",1.77,0.0787,0.632,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["IL-6 Signaling",1.77,0.0787,0.632,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["IL-6 Signaling",1.77,0.0787,0.632,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["IL-6 Signaling",1.77,0.0787,0.632,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["IL-6 Signaling",1.77,0.0787,0.632,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["IL-6 Signaling",1.77,0.0787,0.632,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["IL-6 Signaling",1.77,0.0787,0.632,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["IL-6 Signaling",1.77,0.0787,0.632,"CEBPB","CCAAT/enhancer binding protein beta","Nucleus","transcription regulator",0.021593252,0.020254135,"down",1.3026826,-1.3026826,-0.38148564]
["IL-12 Signaling and Production in Macrophages",1.77,0.0753,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["IL-12 Signaling and Production in Macrophages",1.77,0.0753,"NaN","IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["IL-12 Signaling and Production in Macrophages",1.77,0.0753,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["IL-12 Signaling and Production in Macrophages",1.77,0.0753,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["IL-12 Signaling and Production in Macrophages",1.77,0.0753,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["IL-12 Signaling and Production in Macrophages",1.77,0.0753,"NaN","MYD88","myeloid differentiation primary response 88","Plasma Membrane","other",0.0019091989,0.0009046913,"down",1.3930262,-1.3930262,-0.47822243]
["IL-12 Signaling and Production in Macrophages",1.77,0.0753,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["IL-12 Signaling and Production in Macrophages",1.77,0.0753,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["IL-12 Signaling and Production in Macrophages",1.77,0.0753,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["IL-12 Signaling and Production in Macrophages",1.77,0.0753,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["IL-12 Signaling and Production in Macrophages",1.77,0.0753,"NaN","CEBPB","CCAAT/enhancer binding protein beta","Nucleus","transcription regulator",0.021593252,0.020254135,"down",1.3026826,-1.3026826,-0.38148564]
["B Cell Receptor Signaling",1.77,0.0703,0.832,"RAP2B","RAP2B, member of RAS oncogene family","Plasma Membrane","enzyme",0.0005464768,1.2239901e-05,"down",1.9869581,-1.9869581,-0.9905615]
["B Cell Receptor Signaling",1.77,0.0703,0.832,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["B Cell Receptor Signaling",1.77,0.0703,0.832,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["B Cell Receptor Signaling",1.77,0.0703,0.832,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["B Cell Receptor Signaling",1.77,0.0703,0.832,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["B Cell Receptor Signaling",1.77,0.0703,0.832,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["B Cell Receptor Signaling",1.77,0.0703,0.832,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["B Cell Receptor Signaling",1.77,0.0703,0.832,"PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["B Cell Receptor Signaling",1.77,0.0703,0.832,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["B Cell Receptor Signaling",1.77,0.0703,0.832,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["B Cell Receptor Signaling",1.77,0.0703,0.832,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["B Cell Receptor Signaling",1.77,0.0703,0.832,"RPS6KB2","ribosomal protein S6 kinase B2","Cytoplasm","kinase",0.0016431456,0.0006520507,"down",1.986918,-1.986918,-0.9905323]
["B Cell Receptor Signaling",1.77,0.0703,0.832,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Acute Myeloid Leukemia Signaling",1.77,0.0879,0,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Acute Myeloid Leukemia Signaling",1.77,0.0879,0,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Acute Myeloid Leukemia Signaling",1.77,0.0879,0,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Acute Myeloid Leukemia Signaling",1.77,0.0879,0,"FLT3LG","fms related tyrosine kinase 3 ligand","Extracellular Space","cytokine",0.03553473,0.034377225,"down",1.3344398,-1.3344398,-0.41623417]
["Acute Myeloid Leukemia Signaling",1.77,0.0879,0,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Acute Myeloid Leukemia Signaling",1.77,0.0879,0,"RPS6KB2","ribosomal protein S6 kinase B2","Cytoplasm","kinase",0.0016431456,0.0006520507,"down",1.986918,-1.986918,-0.9905323]
["Acute Myeloid Leukemia Signaling",1.77,0.0879,0,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Acute Myeloid Leukemia Signaling",1.77,0.0879,0,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["TREM1 Signaling",1.73,0.0933,-1.134,"ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["TREM1 Signaling",1.73,0.0933,-1.134,"CXCL8","C-X-C motif chemokine ligand 8","Extracellular Space","cytokine",0.0011259156,0.00022286079,"down",1.5851029,-1.5851029,-0.66457653]
["TREM1 Signaling",1.73,0.0933,-1.134,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["TREM1 Signaling",1.73,0.0933,-1.134,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["TREM1 Signaling",1.73,0.0933,-1.134,"MYD88","myeloid differentiation primary response 88","Plasma Membrane","other",0.0019091989,0.0009046913,"down",1.3930262,-1.3930262,-0.47822243]
["TREM1 Signaling",1.73,0.0933,-1.134,"CASP1","caspase 1","Cytoplasm","peptidase",0.0010976536,0.00020770791,"down",1.8456633,-1.8456633,-0.88413936]
["TREM1 Signaling",1.73,0.0933,-1.134,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Antiproliferative Role of Somatostatin Receptor 2",1.73,0.0933,0.816,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Antiproliferative Role of Somatostatin Receptor 2",1.73,0.0933,0.816,"GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["Antiproliferative Role of Somatostatin Receptor 2",1.73,0.0933,0.816,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Antiproliferative Role of Somatostatin Receptor 2",1.73,0.0933,0.816,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Antiproliferative Role of Somatostatin Receptor 2",1.73,0.0933,0.816,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Antiproliferative Role of Somatostatin Receptor 2",1.73,0.0933,0.816,"CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["Antiproliferative Role of Somatostatin Receptor 2",1.73,0.0933,0.816,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Gap Junction Signaling",1.72,0.0714,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Gap Junction Signaling",1.72,0.0714,"NaN","TUBB3","tubulin beta 3 class III","Cytoplasm","other",0.001459056,0.00047059942,"up",1.4351482,1.4351482,0.52119976]
["Gap Junction Signaling",1.72,0.0714,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Gap Junction Signaling",1.72,0.0714,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Gap Junction Signaling",1.72,0.0714,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Gap Junction Signaling",1.72,0.0714,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Gap Junction Signaling",1.72,0.0714,"NaN","TUBB2A","tubulin beta 2A class IIa","Cytoplasm","other",0.0026605518,0.0015617278,"up",1.4475315,1.4475315,0.5335947]
["Gap Junction Signaling",1.72,0.0714,"NaN","CAV1","caveolin 1","Plasma Membrane","transmembrane receptor",0.0014512807,0.00046188477,"up",1.5792397,1.5792397,0.6592302]
["Gap Junction Signaling",1.72,0.0714,"NaN","PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Gap Junction Signaling",1.72,0.0714,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Gap Junction Signaling",1.72,0.0714,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Gap Junction Signaling",1.72,0.0714,"NaN","ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["Corticotropin Releasing Hormone Signaling",1.72,0.0811,-0.378,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Corticotropin Releasing Hormone Signaling",1.72,0.0811,-0.378,"GLI2","GLI family zinc finger 2","Nucleus","transcription regulator",0.0009526495,0.00013251757,"down",1.5357528,-1.5357528,-0.61894596]
["Corticotropin Releasing Hormone Signaling",1.72,0.0811,-0.378,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Corticotropin Releasing Hormone Signaling",1.72,0.0811,-0.378,"MEF2D","myocyte enhancer factor 2D","Nucleus","transcription regulator",0.0006217929,3.203251e-05,"down",1.3555743,-1.3555743,-0.43890414]
["Corticotropin Releasing Hormone Signaling",1.72,0.0811,-0.378,"MEF2A","myocyte enhancer factor 2A","Nucleus","transcription regulator",0.015937602,0.014585446,"down",1.3274704,-1.3274704,-0.40867972]
["Corticotropin Releasing Hormone Signaling",1.72,0.0811,-0.378,"PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Corticotropin Releasing Hormone Signaling",1.72,0.0811,-0.378,"PTGS2","prostaglandin-endoperoxide synthase 2","Cytoplasm","enzyme",0.0012584343,0.00031259237,"down",1.4767396,-1.4767396,-0.5624155]
["Corticotropin Releasing Hormone Signaling",1.72,0.0811,-0.378,"ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["Corticotropin Releasing Hormone Signaling",1.72,0.0811,-0.378,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["Telomerase Signaling",1.72,0.0811,1.134,"HDAC6","histone deacetylase 6","Nucleus","transcription regulator",0.0060592825,0.0047327504,"up",1.6543902,1.6543902,0.7262995]
["Telomerase Signaling",1.72,0.0811,1.134,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Telomerase Signaling",1.72,0.0811,1.134,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Telomerase Signaling",1.72,0.0811,1.134,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Telomerase Signaling",1.72,0.0811,1.134,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Telomerase Signaling",1.72,0.0811,1.134,"CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["Telomerase Signaling",1.72,0.0811,1.134,"HSP90AA1","heat shock protein 90kDa alpha family class A member 1","Cytoplasm","enzyme",0.0005783946,2.0937947e-05,"up",1.5556576,1.5556576,0.63752455]
["Telomerase Signaling",1.72,0.0811,1.134,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Telomerase Signaling",1.72,0.0811,1.134,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Fcγ Receptor-mediated Phagocytosis in Macrophages and Monocytes",1.72,0.086,-0.707,"MYO5A","myosin VA","Cytoplasm","enzyme",0.0012808557,0.00032983793,"up",1.3758048,1.3758048,0.46027577]
["Fcγ Receptor-mediated Phagocytosis in Macrophages and Monocytes",1.72,0.086,-0.707,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Fcγ Receptor-mediated Phagocytosis in Macrophages and Monocytes",1.72,0.086,-0.707,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Fcγ Receptor-mediated Phagocytosis in Macrophages and Monocytes",1.72,0.086,-0.707,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Fcγ Receptor-mediated Phagocytosis in Macrophages and Monocytes",1.72,0.086,-0.707,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["Fcγ Receptor-mediated Phagocytosis in Macrophages and Monocytes",1.72,0.086,-0.707,"RPS6KB2","ribosomal protein S6 kinase B2","Cytoplasm","kinase",0.0016431456,0.0006520507,"down",1.986918,-1.986918,-0.9905323]
["Fcγ Receptor-mediated Phagocytosis in Macrophages and Monocytes",1.72,0.086,-0.707,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Fcγ Receptor-mediated Phagocytosis in Macrophages and Monocytes",1.72,0.086,-0.707,"PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["CCR3 Signaling in Eosinophils",1.71,0.0769,"NaN","ROCK2","Rho associated coiled-coil containing protein kinase 2","Cytoplasm","kinase",0.0010184328,0.00016622998,"up",1.3479002,1.3479002,0.43071362]
["CCR3 Signaling in Eosinophils",1.71,0.0769,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["CCR3 Signaling in Eosinophils",1.71,0.0769,"NaN","GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["CCR3 Signaling in Eosinophils",1.71,0.0769,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["CCR3 Signaling in Eosinophils",1.71,0.0769,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["CCR3 Signaling in Eosinophils",1.71,0.0769,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["CCR3 Signaling in Eosinophils",1.71,0.0769,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["CCR3 Signaling in Eosinophils",1.71,0.0769,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["CCR3 Signaling in Eosinophils",1.71,0.0769,"NaN","LIMK2","LIM domain kinase 2","Cytoplasm","kinase",0.0035328772,0.002318736,"up",1.3875531,1.3875531,0.47254297]
["CCR3 Signaling in Eosinophils",1.71,0.0769,"NaN","ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["IL-15 Signaling",1.7,0.0921,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["IL-15 Signaling",1.7,0.0921,"NaN","CXCL8","C-X-C motif chemokine ligand 8","Extracellular Space","cytokine",0.0011259156,0.00022286079,"down",1.5851029,-1.5851029,-0.66457653]
["IL-15 Signaling",1.7,0.0921,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["IL-15 Signaling",1.7,0.0921,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["IL-15 Signaling",1.7,0.0921,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["IL-15 Signaling",1.7,0.0921,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["IL-15 Signaling",1.7,0.0921,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Neurotrophin/TRK Signaling",1.7,0.0921,0.378,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Neurotrophin/TRK Signaling",1.7,0.0921,0.378,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Neurotrophin/TRK Signaling",1.7,0.0921,0.378,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Neurotrophin/TRK Signaling",1.7,0.0921,0.378,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["Neurotrophin/TRK Signaling",1.7,0.0921,0.378,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Neurotrophin/TRK Signaling",1.7,0.0921,0.378,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Neurotrophin/TRK Signaling",1.7,0.0921,0.378,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["BMP signaling pathway",1.7,0.0921,1.134,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["BMP signaling pathway",1.7,0.0921,1.134,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["BMP signaling pathway",1.7,0.0921,1.134,"PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["BMP signaling pathway",1.7,0.0921,1.134,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["BMP signaling pathway",1.7,0.0921,1.134,"SMAD5","SMAD family member 5","Nucleus","transcription regulator",0.0014749195,0.00048909907,"down",1.3112969,-1.3112969,-0.3909944]
["BMP signaling pathway",1.7,0.0921,1.134,"BMP6","bone morphogenetic protein 6","Extracellular Space","growth factor",0.0012361597,0.00030026503,"up",1.359715,1.359715,0.44330427]
["BMP signaling pathway",1.7,0.0921,1.134,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["Acute Phase Response Signaling",1.7,0.071,0.905,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Acute Phase Response Signaling",1.7,0.071,0.905,"TRADD","TNFRSF1A associated via death domain","Cytoplasm","other",0.0016301863,0.0006398275,"up",1.3732907,1.3732907,0.457637]
["Acute Phase Response Signaling",1.7,0.071,0.905,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["Acute Phase Response Signaling",1.7,0.071,0.905,"FTL","ferritin, light polypeptide","Cytoplasm","enzyme",0.0011684936,0.0002475878,"down",1.3095047,-1.3095047,-0.38902128]
["Acute Phase Response Signaling",1.7,0.071,0.905,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Acute Phase Response Signaling",1.7,0.071,0.905,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Acute Phase Response Signaling",1.7,0.071,0.905,"MYD88","myeloid differentiation primary response 88","Plasma Membrane","other",0.0019091989,0.0009046913,"down",1.3930262,-1.3930262,-0.47822243]
["Acute Phase Response Signaling",1.7,0.071,0.905,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Acute Phase Response Signaling",1.7,0.071,0.905,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Acute Phase Response Signaling",1.7,0.071,0.905,"CEBPB","CCAAT/enhancer binding protein beta","Nucleus","transcription regulator",0.021593252,0.020254135,"down",1.3026826,-1.3026826,-0.38148564]
["Acute Phase Response Signaling",1.7,0.071,0.905,"SERPINE1","serpin family E member 1","Extracellular Space","other",0.0016010772,0.00060374127,"up",1.3806411,1.3806411,0.46533832]
["Acute Phase Response Signaling",1.7,0.071,0.905,"CRABP2","cellular retinoic acid binding protein 2","Cytoplasm","transporter",0.004642051,0.0033346,"up",1.3608729,1.3608729,0.44453228]
["Leukocyte Extravasation Signaling",1.69,0.0667,-0.277,"ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["Leukocyte Extravasation Signaling",1.69,0.0667,-0.277,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Leukocyte Extravasation Signaling",1.69,0.0667,-0.277,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Leukocyte Extravasation Signaling",1.69,0.0667,-0.277,"CXCR4","C-X-C motif chemokine receptor 4","Plasma Membrane","G-protein coupled receptor",0.0018305046,0.00083504117,"down",1.3248457,-1.3248457,-0.4058243]
["Leukocyte Extravasation Signaling",1.69,0.0667,-0.277,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Leukocyte Extravasation Signaling",1.69,0.0667,-0.277,"WASL","Wiskott-Aldrich syndrome like","Cytoplasm","other",0.00040977335,6.54692e-06,"up",1.4019742,1.4019742,0.4874598]
["Leukocyte Extravasation Signaling",1.69,0.0667,-0.277,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Leukocyte Extravasation Signaling",1.69,0.0667,-0.277,"MLLT4","myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4","Nucleus","other",0.0013056329,0.00034460775,"up",1.7435131,1.7435131,0.8019972]
["Leukocyte Extravasation Signaling",1.69,0.0667,-0.277,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Leukocyte Extravasation Signaling",1.69,0.0667,-0.277,"ROCK2","Rho associated coiled-coil containing protein kinase 2","Cytoplasm","kinase",0.0010184328,0.00016622998,"up",1.3479002,1.3479002,0.43071362]
["Leukocyte Extravasation Signaling",1.69,0.0667,-0.277,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Leukocyte Extravasation Signaling",1.69,0.0667,-0.277,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Leukocyte Extravasation Signaling",1.69,0.0667,-0.277,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["Leukocyte Extravasation Signaling",1.69,0.0667,-0.277,"ARHGAP12","Rho GTPase activating protein 12","Cytoplasm","other",0.009885796,0.008399947,"down",1.4160204,-1.4160204,-0.501842]
["RAR Activation",1.68,0.0684,"NaN","PBRM1","polybromo 1","Nucleus","other",0.0055692703,0.0042261216,"down",1.4428215,-1.4428215,-0.5288928]
["RAR Activation",1.68,0.0684,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["RAR Activation",1.68,0.0684,"NaN","NSD1","nuclear receptor binding SET domain protein 1","Nucleus","transcription regulator",0.004395149,0.0030966685,"down",1.5514004,-1.5514004,-0.6335711]
["RAR Activation",1.68,0.0684,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["RAR Activation",1.68,0.0684,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["RAR Activation",1.68,0.0684,"NaN","MED1","mediator complex subunit 1","Nucleus","transcription regulator",0.007830824,0.006407651,"down",1.3726159,-1.3726159,-0.456928]
["RAR Activation",1.68,0.0684,"NaN","PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["RAR Activation",1.68,0.0684,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["RAR Activation",1.68,0.0684,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["RAR Activation",1.68,0.0684,"NaN","SMAD5","SMAD family member 5","Nucleus","transcription regulator",0.0014749195,0.00048909907,"down",1.3112969,-1.3112969,-0.3909944]
["RAR Activation",1.68,0.0684,"NaN","CRABP2","cellular retinoic acid binding protein 2","Cytoplasm","transporter",0.004642051,0.0033346,"up",1.3608729,1.3608729,0.44453228]
["RAR Activation",1.68,0.0684,"NaN","CITED2","Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2","Nucleus","transcription regulator",0.010849081,0.009426419,"up",1.4059179,1.4059179,0.49151233]
["RAR Activation",1.68,0.0684,"NaN","PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["Angiopoietin Signaling",1.68,0.0909,0,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Angiopoietin Signaling",1.68,0.0909,0,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["Angiopoietin Signaling",1.68,0.0909,0,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Angiopoietin Signaling",1.68,0.0909,0,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Angiopoietin Signaling",1.68,0.0909,0,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Angiopoietin Signaling",1.68,0.0909,0,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Angiopoietin Signaling",1.68,0.0909,0,"BIRC5","baculoviral IAP repeat containing 5","Cytoplasm","other",0.0018505693,0.00084797834,"up",1.5707992,1.5707992,0.6514988]
["Paxillin Signaling",1.67,0.0796,0,"ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["Paxillin Signaling",1.67,0.0796,0,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Paxillin Signaling",1.67,0.0796,0,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Paxillin Signaling",1.67,0.0796,0,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Paxillin Signaling",1.67,0.0796,0,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["Paxillin Signaling",1.67,0.0796,0,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Paxillin Signaling",1.67,0.0796,0,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Paxillin Signaling",1.67,0.0796,0,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Paxillin Signaling",1.67,0.0796,0,"ITGB8","integrin subunit beta 8","Plasma Membrane","other",0.0039384346,0.0026866843,"up",1.8310404,1.8310404,0.8726636]
["P2Y Purigenic Receptor Signaling Pathway",1.67,0.0758,1,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["P2Y Purigenic Receptor Signaling Pathway",1.67,0.0758,1,"GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["P2Y Purigenic Receptor Signaling Pathway",1.67,0.0758,1,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["P2Y Purigenic Receptor Signaling Pathway",1.67,0.0758,1,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["P2Y Purigenic Receptor Signaling Pathway",1.67,0.0758,1,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["P2Y Purigenic Receptor Signaling Pathway",1.67,0.0758,1,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["P2Y Purigenic Receptor Signaling Pathway",1.67,0.0758,1,"PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["P2Y Purigenic Receptor Signaling Pathway",1.67,0.0758,1,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["P2Y Purigenic Receptor Signaling Pathway",1.67,0.0758,1,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["P2Y Purigenic Receptor Signaling Pathway",1.67,0.0758,1,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["Role of Osteoblasts, Osteoclasts and Chondrocytes in Rheumatoid Arthritis",1.66,0.0647,"NaN","ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["Role of Osteoblasts, Osteoclasts and Chondrocytes in Rheumatoid Arthritis",1.66,0.0647,"NaN","FZD10","frizzled class receptor 10","Plasma Membrane","G-protein coupled receptor",0.00084399927,9.184798e-05,"down",1.4670624,-1.4670624,-0.5529302]
["Role of Osteoblasts, Osteoclasts and Chondrocytes in Rheumatoid Arthritis",1.66,0.0647,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Role of Osteoblasts, Osteoclasts and Chondrocytes in Rheumatoid Arthritis",1.66,0.0647,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Role of Osteoblasts, Osteoclasts and Chondrocytes in Rheumatoid Arthritis",1.66,0.0647,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Role of Osteoblasts, Osteoclasts and Chondrocytes in Rheumatoid Arthritis",1.66,0.0647,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Role of Osteoblasts, Osteoclasts and Chondrocytes in Rheumatoid Arthritis",1.66,0.0647,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Role of Osteoblasts, Osteoclasts and Chondrocytes in Rheumatoid Arthritis",1.66,0.0647,"NaN","SMAD5","SMAD family member 5","Nucleus","transcription regulator",0.0014749195,0.00048909907,"down",1.3112969,-1.3112969,-0.3909944]
["Role of Osteoblasts, Osteoclasts and Chondrocytes in Rheumatoid Arthritis",1.66,0.0647,"NaN","FZD1","frizzled class receptor 1","Plasma Membrane","G-protein coupled receptor",0.0036817046,0.002460812,"down",1.529664,-1.529664,-0.6132148]
["Role of Osteoblasts, Osteoclasts and Chondrocytes in Rheumatoid Arthritis",1.66,0.0647,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Role of Osteoblasts, Osteoclasts and Chondrocytes in Rheumatoid Arthritis",1.66,0.0647,"NaN","TRADD","TNFRSF1A associated via death domain","Cytoplasm","other",0.0016301863,0.0006398275,"up",1.3732907,1.3732907,0.457637]
["Role of Osteoblasts, Osteoclasts and Chondrocytes in Rheumatoid Arthritis",1.66,0.0647,"NaN","IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["Role of Osteoblasts, Osteoclasts and Chondrocytes in Rheumatoid Arthritis",1.66,0.0647,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Role of Osteoblasts, Osteoclasts and Chondrocytes in Rheumatoid Arthritis",1.66,0.0647,"NaN","FZD5","frizzled class receptor 5","Plasma Membrane","G-protein coupled receptor",0.0011555209,0.00024123449,"down",1.5153433,-1.5153433,-0.59964466]
["Role of Osteoblasts, Osteoclasts and Chondrocytes in Rheumatoid Arthritis",1.66,0.0647,"NaN","BMP6","bone morphogenetic protein 6","Extracellular Space","growth factor",0.0012361597,0.00030026503,"up",1.359715,1.359715,0.44330427]
["Superpathway of Geranylgeranyldiphosphate Biosynthesis I (via Mevalonate)",1.66,0.176,"NaN","PMVK","phosphomevalonate kinase","Cytoplasm","kinase",0.0015215367,0.0005270031,"down",1.3550662,-1.3550662,-0.4383633]
["Superpathway of Geranylgeranyldiphosphate Biosynthesis I (via Mevalonate)",1.66,0.176,"NaN","HMGCR","3-hydroxy-3-methylglutaryl-CoA reductase","Cytoplasm","enzyme",0.0014677041,0.00048228173,"up",1.3671681,1.3671681,0.4511906]
["Superpathway of Geranylgeranyldiphosphate Biosynthesis I (via Mevalonate)",1.66,0.176,"NaN","GGPS1","geranylgeranyl diphosphate synthase 1","Cytoplasm","enzyme",0.0020834338,0.0010650456,"up",1.3196927,1.3196927,0.40020207]
["HIF1α Signaling",1.63,0.0783,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["HIF1α Signaling",1.63,0.0783,"NaN","SLC2A1","solute carrier family 2 member 1","Plasma Membrane","transporter",0.0010998568,0.00021028184,"down",1.3829497,-1.3829497,-0.4677487]
["HIF1α Signaling",1.63,0.0783,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["HIF1α Signaling",1.63,0.0783,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["HIF1α Signaling",1.63,0.0783,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["HIF1α Signaling",1.63,0.0783,"NaN","HSP90AA1","heat shock protein 90kDa alpha family class A member 1","Cytoplasm","enzyme",0.0005783946,2.0937947e-05,"up",1.5556576,1.5556576,0.63752455]
["HIF1α Signaling",1.63,0.0783,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["HIF1α Signaling",1.63,0.0783,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["HIF1α Signaling",1.63,0.0783,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Erythropoietin Signaling",1.62,0.0886,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Erythropoietin Signaling",1.62,0.0886,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Erythropoietin Signaling",1.62,0.0886,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Erythropoietin Signaling",1.62,0.0886,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Erythropoietin Signaling",1.62,0.0886,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Erythropoietin Signaling",1.62,0.0886,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Erythropoietin Signaling",1.62,0.0886,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Superpathway of Serine and Glycine Biosynthesis I",1.62,0.286,"NaN","SHMT1","serine hydroxymethyltransferase 1","Cytoplasm","enzyme",0.0008942897,0.000111482994,"up",1.4391686,1.4391686,0.5252356]
["Superpathway of Serine and Glycine Biosynthesis I",1.62,0.286,"NaN","SHMT2","serine hydroxymethyltransferase 2","Cytoplasm","enzyme",0.0022647758,0.0012213683,"down",1.6496395,-1.6496395,-0.72215074]
["4-1BB Signaling in T Lymphocytes",1.61,0.129,2,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["4-1BB Signaling in T Lymphocytes",1.61,0.129,2,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["4-1BB Signaling in T Lymphocytes",1.61,0.129,2,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["4-1BB Signaling in T Lymphocytes",1.61,0.129,2,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["TR/RXR Activation",1.59,0.0816,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["TR/RXR Activation",1.59,0.0816,"NaN","SLC2A1","solute carrier family 2 member 1","Plasma Membrane","transporter",0.0010998568,0.00021028184,"down",1.3829497,-1.3829497,-0.4677487]
["TR/RXR Activation",1.59,0.0816,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["TR/RXR Activation",1.59,0.0816,"NaN","PDE3B","phosphodiesterase 3B","Cytoplasm","enzyme",0.0026252405,0.0015308249,"up",1.3255126,1.3255126,0.40655044]
["TR/RXR Activation",1.59,0.0816,"NaN","MED1","mediator complex subunit 1","Nucleus","transcription regulator",0.007830824,0.006407651,"down",1.3726159,-1.3726159,-0.456928]
["TR/RXR Activation",1.59,0.0816,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["TR/RXR Activation",1.59,0.0816,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["TR/RXR Activation",1.59,0.0816,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["ErbB Signaling",1.59,0.0816,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["ErbB Signaling",1.59,0.0816,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["ErbB Signaling",1.59,0.0816,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["ErbB Signaling",1.59,0.0816,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["ErbB Signaling",1.59,0.0816,"NaN","CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["ErbB Signaling",1.59,0.0816,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["ErbB Signaling",1.59,0.0816,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["ErbB Signaling",1.59,0.0816,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["D-myo-inositol (1,4,5)-trisphosphate Degradation",1.59,0.167,"NaN","BPNT1","3'(2'), 5'-bisphosphate nucleotidase 1","Nucleus","phosphatase",0.0014996352,0.000517316,"down",2.1743834,-2.1743834,-1.1206063]
["D-myo-inositol (1,4,5)-trisphosphate Degradation",1.59,0.167,"NaN","IMPA2","inositol monophosphatase 2","Cytoplasm","phosphatase",0.00084399927,9.163144e-05,"down",1.303337,-1.303337,-0.38221014]
["D-myo-inositol (1,4,5)-trisphosphate Degradation",1.59,0.167,"NaN","INPP5A","inositol polyphosphate-5-phosphatase A","Plasma Membrane","phosphatase",0.0017193076,0.00071636395,"up",1.6724749,1.6724749,0.7419845]
["Phospholipase C Signaling",1.59,0.0633,-0.707,"ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["Phospholipase C Signaling",1.59,0.0633,-0.707,"TGM2","transglutaminase 2","Cytoplasm","enzyme",0.0012591777,0.00031366711,"down",1.4611537,-1.4611537,-0.547108]
["Phospholipase C Signaling",1.59,0.0633,-0.707,"HDAC6","histone deacetylase 6","Nucleus","transcription regulator",0.0060592825,0.0047327504,"up",1.6543902,1.6543902,0.7262995]
["Phospholipase C Signaling",1.59,0.0633,-0.707,"GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["Phospholipase C Signaling",1.59,0.0633,-0.707,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Phospholipase C Signaling",1.59,0.0633,-0.707,"AHNAK","AHNAK nucleoprotein","Nucleus","other",0.0006672249,3.9087754e-05,"down",1.5146648,-1.5146648,-0.59899855]
["Phospholipase C Signaling",1.59,0.0633,-0.707,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Phospholipase C Signaling",1.59,0.0633,-0.707,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Phospholipase C Signaling",1.59,0.0633,-0.707,"MEF2D","myocyte enhancer factor 2D","Nucleus","transcription regulator",0.0006217929,3.203251e-05,"down",1.3555743,-1.3555743,-0.43890414]
["Phospholipase C Signaling",1.59,0.0633,-0.707,"RALB","v-ral simian leukemia viral oncogene homolog B","Cytoplasm","enzyme",0.0022762846,0.0012371538,"up",1.7571107,1.7571107,0.81320506]
["Phospholipase C Signaling",1.59,0.0633,-0.707,"MEF2A","myocyte enhancer factor 2A","Nucleus","transcription regulator",0.015937602,0.014585446,"down",1.3274704,-1.3274704,-0.40867972]
["Phospholipase C Signaling",1.59,0.0633,-0.707,"RHOU","ras homolog family member U","Cytoplasm","enzyme",0.0009194498,0.00012193339,"down",1.7715495,-1.7715495,-0.82501173]
["Phospholipase C Signaling",1.59,0.0633,-0.707,"MYL6B","myosin light chain 6B","Cytoplasm","other",0.0037700427,0.0025393397,"up",1.3426967,1.3426967,0.4251334]
["Phospholipase C Signaling",1.59,0.0633,-0.707,"ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["Phospholipase C Signaling",1.59,0.0633,-0.707,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses",1.57,0.073,-0.333,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses",1.57,0.073,-0.333,"CXCL8","C-X-C motif chemokine ligand 8","Extracellular Space","cytokine",0.0011259156,0.00022286079,"down",1.5851029,-1.5851029,-0.66457653]
["Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses",1.57,0.073,-0.333,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses",1.57,0.073,-0.333,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses",1.57,0.073,-0.333,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses",1.57,0.073,-0.333,"MYD88","myeloid differentiation primary response 88","Plasma Membrane","other",0.0019091989,0.0009046913,"down",1.3930262,-1.3930262,-0.47822243]
["Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses",1.57,0.073,-0.333,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses",1.57,0.073,-0.333,"CASP1","caspase 1","Cytoplasm","peptidase",0.0010976536,0.00020770791,"down",1.8456633,-1.8456633,-0.88413936]
["Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses",1.57,0.073,-0.333,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses",1.57,0.073,-0.333,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Regulation of eIF4 and p70S6K Signaling",1.56,0.0701,0.378,"ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["Regulation of eIF4 and p70S6K Signaling",1.56,0.0701,0.378,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Regulation of eIF4 and p70S6K Signaling",1.56,0.0701,0.378,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Regulation of eIF4 and p70S6K Signaling",1.56,0.0701,0.378,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Regulation of eIF4 and p70S6K Signaling",1.56,0.0701,0.378,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Regulation of eIF4 and p70S6K Signaling",1.56,0.0701,0.378,"PAIP1","poly(A) binding protein interacting protein 1","Cytoplasm","translation regulator",0.009647093,0.008172193,"up",1.4854679,1.4854679,0.5709174]
["Regulation of eIF4 and p70S6K Signaling",1.56,0.0701,0.378,"EIF3J","eukaryotic translation initiation factor 3 subunit J","Cytoplasm","translation regulator",0.0008942897,0.00011461672,"down",1.5294574,-1.5294574,-0.61301994]
["Regulation of eIF4 and p70S6K Signaling",1.56,0.0701,0.378,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Regulation of eIF4 and p70S6K Signaling",1.56,0.0701,0.378,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Regulation of eIF4 and p70S6K Signaling",1.56,0.0701,0.378,"RPS27A","ribosomal protein S27a","Cytoplasm","other",0.0033264575,0.002133116,"down",1.341015,-1.341015,-0.42332536]
["Regulation of eIF4 and p70S6K Signaling",1.56,0.0701,0.378,"EIF3M","eukaryotic translation initiation factor 3 subunit M","Cytoplasm","other",0.0028598784,0.0017288154,"down",1.3275427,-1.3275427,-0.40875822]
["IL-2 Signaling",1.56,0.0938,0.816,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["IL-2 Signaling",1.56,0.0938,0.816,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["IL-2 Signaling",1.56,0.0938,0.816,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["IL-2 Signaling",1.56,0.0938,0.816,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["IL-2 Signaling",1.56,0.0938,0.816,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["IL-2 Signaling",1.56,0.0938,0.816,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["DNA damage-induced 14-3-3σ Signaling",1.53,0.158,"NaN","CCNE1","cyclin E1","Nucleus","transcription regulator",0.0013342145,0.00036659295,"down",2.6488216,-2.6488216,-1.4053507]
["DNA damage-induced 14-3-3σ Signaling",1.53,0.158,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["DNA damage-induced 14-3-3σ Signaling",1.53,0.158,"NaN","RAD1","RAD1 checkpoint DNA exonuclease","Nucleus","enzyme",0.0015215367,0.00052814756,"down",1.6791438,-1.6791438,-0.7477258]
["Thrombopoietin Signaling",1.53,0.0923,0,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Thrombopoietin Signaling",1.53,0.0923,0,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Thrombopoietin Signaling",1.53,0.0923,0,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Thrombopoietin Signaling",1.53,0.0923,0,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Thrombopoietin Signaling",1.53,0.0923,0,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Thrombopoietin Signaling",1.53,0.0923,0,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["IL-3 Signaling",1.52,0.0843,0.378,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["IL-3 Signaling",1.52,0.0843,0.378,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["IL-3 Signaling",1.52,0.0843,0.378,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["IL-3 Signaling",1.52,0.0843,0.378,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["IL-3 Signaling",1.52,0.0843,0.378,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["IL-3 Signaling",1.52,0.0843,0.378,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["IL-3 Signaling",1.52,0.0843,0.378,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Prolactin Signaling",1.52,0.0843,0,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Prolactin Signaling",1.52,0.0843,0,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Prolactin Signaling",1.52,0.0843,0,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Prolactin Signaling",1.52,0.0843,0,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Prolactin Signaling",1.52,0.0843,0,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Prolactin Signaling",1.52,0.0843,0,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Prolactin Signaling",1.52,0.0843,0,"CEBPB","CCAAT/enhancer binding protein beta","Nucleus","transcription regulator",0.021593252,0.020254135,"down",1.3026826,-1.3026826,-0.38148564]
["Cell Cycle: G2/M DNA Damage Checkpoint Regulation",1.51,0.102,0.447,"CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["Cell Cycle: G2/M DNA Damage Checkpoint Regulation",1.51,0.102,0.447,"CHEK2","checkpoint kinase 2","Nucleus","kinase",0.0028598784,0.0017272087,"up",1.3150214,1.3150214,0.39508626]
["Cell Cycle: G2/M DNA Damage Checkpoint Regulation",1.51,0.102,0.447,"SKP2","S-phase kinase-associated protein 2, E3 ubiquitin protein ligase","Nucleus","enzyme",0.0014867174,0.000499228,"up",1.348095,1.348095,0.4309222]
["Cell Cycle: G2/M DNA Damage Checkpoint Regulation",1.51,0.102,0.447,"PPM1D","protein phosphatase, Mg2+/Mn2+ dependent 1D","Cytoplasm","phosphatase",0.0017398865,0.0007406382,"down",1.7109653,-1.7109653,-0.7748105]
["Cell Cycle: G2/M DNA Damage Checkpoint Regulation",1.51,0.102,0.447,"CHEK1","checkpoint kinase 1","Nucleus","kinase",0.0010877973,0.00019520131,"up",1.4226359,1.4226359,0.5085665]
["Cancer Drug Resistance By Drug Efflux",1.51,0.102,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Cancer Drug Resistance By Drug Efflux",1.51,0.102,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Cancer Drug Resistance By Drug Efflux",1.51,0.102,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Cancer Drug Resistance By Drug Efflux",1.51,0.102,"NaN","PTGS2","prostaglandin-endoperoxide synthase 2","Cytoplasm","enzyme",0.0012584343,0.00031259237,"down",1.4767396,-1.4767396,-0.5624155]
["Cancer Drug Resistance By Drug Efflux",1.51,0.102,"NaN","PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["fMLP Signaling in Neutrophils",1.5,0.0744,0,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["fMLP Signaling in Neutrophils",1.5,0.0744,0,"GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["fMLP Signaling in Neutrophils",1.5,0.0744,0,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["fMLP Signaling in Neutrophils",1.5,0.0744,0,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["fMLP Signaling in Neutrophils",1.5,0.0744,0,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["fMLP Signaling in Neutrophils",1.5,0.0744,0,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["fMLP Signaling in Neutrophils",1.5,0.0744,0,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["fMLP Signaling in Neutrophils",1.5,0.0744,0,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["fMLP Signaling in Neutrophils",1.5,0.0744,0,"ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["UVA-Induced MAPK Signaling",1.5,0.0784,0,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["UVA-Induced MAPK Signaling",1.5,0.0784,0,"TIPARP","TCDD inducible poly(ADP-ribose) polymerase","Nucleus","enzyme",0.0011442282,0.00023684064,"down",1.3731275,-1.3731275,-0.45746553]
["UVA-Induced MAPK Signaling",1.5,0.0784,0,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["UVA-Induced MAPK Signaling",1.5,0.0784,0,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["UVA-Induced MAPK Signaling",1.5,0.0784,0,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["UVA-Induced MAPK Signaling",1.5,0.0784,0,"RPS6KB2","ribosomal protein S6 kinase B2","Cytoplasm","kinase",0.0016431456,0.0006520507,"down",1.986918,-1.986918,-0.9905323]
["UVA-Induced MAPK Signaling",1.5,0.0784,0,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["UVA-Induced MAPK Signaling",1.5,0.0784,0,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Mitotic Roles of Polo-Like Kinase",1.5,0.0909,"NaN","HSP90AA1","heat shock protein 90kDa alpha family class A member 1","Cytoplasm","enzyme",0.0005783946,2.0937947e-05,"up",1.5556576,1.5556576,0.63752455]
["Mitotic Roles of Polo-Like Kinase",1.5,0.0909,"NaN","CDC23","cell division cycle 23","Nucleus","enzyme",0.001459056,0.0004736629,"down",1.4613066,-1.4613066,-0.54725885]
["Mitotic Roles of Polo-Like Kinase",1.5,0.0909,"NaN","CHEK2","checkpoint kinase 2","Nucleus","kinase",0.0028598784,0.0017272087,"up",1.3150214,1.3150214,0.39508626]
["Mitotic Roles of Polo-Like Kinase",1.5,0.0909,"NaN","CDC27","cell division cycle 27","Nucleus","other",0.0016711045,0.00067578256,"up",1.3830807,1.3830807,0.46788535]
["Mitotic Roles of Polo-Like Kinase",1.5,0.0909,"NaN","RAD21","RAD21 cohesin complex component","Nucleus","transcription regulator",0.0022128797,0.0011741032,"down",1.5499305,-1.5499305,-0.63220346]
["Mitotic Roles of Polo-Like Kinase",1.5,0.0909,"NaN","SMC1A","structural maintenance of chromosomes 1A","Nucleus","transporter",0.0036513812,0.002431109,"up",1.3589398,1.3589398,0.44248152]
["Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis",1.49,0.0583,"NaN","CXCL8","C-X-C motif chemokine ligand 8","Extracellular Space","cytokine",0.0011259156,0.00022286079,"down",1.5851029,-1.5851029,-0.66457653]
["Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis",1.49,0.0583,"NaN","FZD10","frizzled class receptor 10","Plasma Membrane","G-protein coupled receptor",0.00084399927,9.184798e-05,"down",1.4670624,-1.4670624,-0.5529302]
["Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis",1.49,0.0583,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis",1.49,0.0583,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis",1.49,0.0583,"NaN","MYD88","myeloid differentiation primary response 88","Plasma Membrane","other",0.0019091989,0.0009046913,"down",1.3930262,-1.3930262,-0.47822243]
["Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis",1.49,0.0583,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis",1.49,0.0583,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis",1.49,0.0583,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis",1.49,0.0583,"NaN","FZD1","frizzled class receptor 1","Plasma Membrane","G-protein coupled receptor",0.0036817046,0.002460812,"down",1.529664,-1.529664,-0.6132148]
["Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis",1.49,0.0583,"NaN","CEBPB","CCAAT/enhancer binding protein beta","Nucleus","transcription regulator",0.021593252,0.020254135,"down",1.3026826,-1.3026826,-0.38148564]
["Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis",1.49,0.0583,"NaN","ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis",1.49,0.0583,"NaN","ROCK2","Rho associated coiled-coil containing protein kinase 2","Cytoplasm","kinase",0.0010184328,0.00016622998,"up",1.3479002,1.3479002,0.43071362]
["Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis",1.49,0.0583,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis",1.49,0.0583,"NaN","TRADD","TNFRSF1A associated via death domain","Cytoplasm","other",0.0016301863,0.0006398275,"up",1.3732907,1.3732907,0.457637]
["Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis",1.49,0.0583,"NaN","IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis",1.49,0.0583,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis",1.49,0.0583,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis",1.49,0.0583,"NaN","FZD5","frizzled class receptor 5","Plasma Membrane","G-protein coupled receptor",0.0011555209,0.00024123449,"down",1.5153433,-1.5153433,-0.59964466]
["RhoA Signaling",1.48,0.0738,3,"ROCK2","Rho associated coiled-coil containing protein kinase 2","Cytoplasm","kinase",0.0010184328,0.00016622998,"up",1.3479002,1.3479002,0.43071362]
["RhoA Signaling",1.48,0.0738,3,"SEPT8","septin 8","Extracellular Space","other",0.0012172924,0.0002738324,"up",1.4083673,1.4083673,0.4940236]
["RhoA Signaling",1.48,0.0738,3,"NEDD4","neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase","Cytoplasm","enzyme",0.00067191356,4.1885378e-05,"up",2.6203134,2.6203134,1.3897394]
["RhoA Signaling",1.48,0.0738,3,"IGF1R","insulin like growth factor 1 receptor","Plasma Membrane","transmembrane receptor",0.0016147236,0.0006161828,"up",1.8701973,1.8701973,0.90319043]
["RhoA Signaling",1.48,0.0738,3,"ARHGAP12","Rho GTPase activating protein 12","Cytoplasm","other",0.009885796,0.008399947,"down",1.4160204,-1.4160204,-0.501842]
["RhoA Signaling",1.48,0.0738,3,"LIMK2","LIM domain kinase 2","Cytoplasm","kinase",0.0035328772,0.002318736,"up",1.3875531,1.3875531,0.47254297]
["RhoA Signaling",1.48,0.0738,3,"MYL6B","myosin light chain 6B","Cytoplasm","other",0.0037700427,0.0025393397,"up",1.3426967,1.3426967,0.4251334]
["RhoA Signaling",1.48,0.0738,3,"SEPT6","septin 6","Cytoplasm","other",0.00077926775,7.637247e-05,"up",1.5135813,1.5135813,0.59796613]
["RhoA Signaling",1.48,0.0738,3,"SEPT2","septin 2","Cytoplasm","enzyme",0.0015251196,0.0005359594,"up",1.938313,1.938313,0.95480156]
["Superpathway of Inositol Phosphate Compounds",1.48,0.0625,"NaN","MTMR9","myotubularin related protein 9","Cytoplasm","phosphatase",0.0011428653,0.0002310908,"down",1.3561463,-1.3561463,-0.43951285]
["Superpathway of Inositol Phosphate Compounds",1.48,0.0625,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Superpathway of Inositol Phosphate Compounds",1.48,0.0625,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Superpathway of Inositol Phosphate Compounds",1.48,0.0625,"NaN","PPFIA3","PTPRF interacting protein alpha 3","Plasma Membrane","phosphatase",0.0022608375,0.0012176248,"up",1.4032409,1.4032409,0.4887627]
["Superpathway of Inositol Phosphate Compounds",1.48,0.0625,"NaN","NUDT12","nudix hydrolase 12","Cytoplasm","phosphatase",0.0015242294,0.00053365715,"up",1.4112375,1.4112375,0.49696076]
["Superpathway of Inositol Phosphate Compounds",1.48,0.0625,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Superpathway of Inositol Phosphate Compounds",1.48,0.0625,"NaN","STYX","serine/threonine/tyrosine interacting protein","Cytoplasm","phosphatase",0.0006217929,2.9874785e-05,"up",1.4957032,1.4957032,0.58082396]
["Superpathway of Inositol Phosphate Compounds",1.48,0.0625,"NaN","STYXL1","serine/threonine/tyrosine interacting-like 1","Cytoplasm","phosphatase",0.0017035499,0.00070178014,"up",1.310616,1.310616,0.39024505]
["Superpathway of Inositol Phosphate Compounds",1.48,0.0625,"NaN","INPP5A","inositol polyphosphate-5-phosphatase A","Plasma Membrane","phosphatase",0.0017193076,0.00071636395,"up",1.6724749,1.6724749,0.7419845]
["Superpathway of Inositol Phosphate Compounds",1.48,0.0625,"NaN","PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["Superpathway of Inositol Phosphate Compounds",1.48,0.0625,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Superpathway of Inositol Phosphate Compounds",1.48,0.0625,"NaN","PPM1H","protein phosphatase, Mg2+/Mn2+ dependent 1H","Other","phosphatase",0.001395873,0.00041960352,"up",1.558836,1.558836,0.64046913]
["Superpathway of Inositol Phosphate Compounds",1.48,0.0625,"NaN","MTMR2","myotubularin related protein 2","Cytoplasm","phosphatase",0.001395873,0.000419132,"up",1.3830658,1.3830658,0.46786982]
["Superpathway of Inositol Phosphate Compounds",1.48,0.0625,"NaN","PPM1F","protein phosphatase, Mg2+/Mn2+ dependent 1F","Cytoplasm","phosphatase",0.0016241793,0.0006365216,"down",1.3318694,-1.3318694,-0.41345257]
["Remodeling of Epithelial Adherens Junctions",1.45,0.0882,2,"MET","MET proto-oncogene, receptor tyrosine kinase","Plasma Membrane","kinase",0.0008691947,0.00010051858,"up",1.5833938,1.5833938,0.66302013]
["Remodeling of Epithelial Adherens Junctions",1.45,0.0882,2,"CDH1","cadherin 1","Plasma Membrane","other",0.0017019173,0.0006999703,"up",1.452055,1.452055,0.5380961]
["Remodeling of Epithelial Adherens Junctions",1.45,0.0882,2,"TUBB3","tubulin beta 3 class III","Cytoplasm","other",0.001459056,0.00047059942,"up",1.4351482,1.4351482,0.52119976]
["Remodeling of Epithelial Adherens Junctions",1.45,0.0882,2,"RAB5A","RAB5A, member RAS oncogene family","Cytoplasm","enzyme",0.001415604,0.00043224083,"up",1.4926699,1.4926699,0.57789516]
["Remodeling of Epithelial Adherens Junctions",1.45,0.0882,2,"TUBB2A","tubulin beta 2A class IIa","Cytoplasm","other",0.0026605518,0.0015617278,"up",1.4475315,1.4475315,0.5335947]
["Remodeling of Epithelial Adherens Junctions",1.45,0.0882,2,"CBLL1","Cbl proto-oncogene like 1","Nucleus","enzyme",0.0012361597,0.0003000335,"down",1.588879,-1.588879,-0.6680092]
["Acyl Carrier Protein Metabolism",1.44,1,"NaN","AASDHPPT","aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase","Cytoplasm","enzyme",0.00171664,0.0007141577,"down",1.6685405,-1.6685405,-0.73858666]
["Thiamin Salvage III",1.44,1,"NaN","TPK1","thiamin pyrophosphokinase 1","Cytoplasm","kinase",0.0014617549,0.00047654973,"up",1.3644428,1.3644428,0.44831192]
["Asparagine Biosynthesis I",1.44,1,"NaN","ASNS","asparagine synthetase (glutamine-hydrolyzing)","Cytoplasm","enzyme",0.0017067622,0.0007060103,"down",1.8762589,-1.8762589,-0.90785885]
["D-mannose Degradation",1.44,1,"NaN","MPI","mannose phosphate isomerase","Cytoplasm","enzyme",0.00091646257,0.00012077414,"up",1.4872181,1.4872181,0.5726163]
["Amyloid Processing",1.44,0.098,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Amyloid Processing",1.44,0.098,"NaN","PSENEN","presenilin enhancer gamma secretase subunit","Plasma Membrane","peptidase",0.0017462111,0.00074735825,"up",1.374307,1.374307,0.45870435]
["Amyloid Processing",1.44,0.098,"NaN","PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Amyloid Processing",1.44,0.098,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Amyloid Processing",1.44,0.098,"NaN","APH1B","aph-1 homolog B, gamma secretase subunit","Other","peptidase",0.0012306612,0.00029680028,"up",1.5021218,1.5021218,0.5870018]
["IL-4 Signaling",1.42,0.0805,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["IL-4 Signaling",1.42,0.0805,"NaN","IL13RA1","interleukin 13 receptor subunit alpha 1","Plasma Membrane","transmembrane receptor",0.0012361597,0.00030132057,"down",1.4217091,-1.4217091,-0.50762624]
["IL-4 Signaling",1.42,0.0805,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["IL-4 Signaling",1.42,0.0805,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["IL-4 Signaling",1.42,0.0805,"NaN","RPS6KB2","ribosomal protein S6 kinase B2","Cytoplasm","kinase",0.0016431456,0.0006520507,"down",1.986918,-1.986918,-0.9905323]
["IL-4 Signaling",1.42,0.0805,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["IL-4 Signaling",1.42,0.0805,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["ErbB2-ErbB3 Signaling",1.42,0.087,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["ErbB2-ErbB3 Signaling",1.42,0.087,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["ErbB2-ErbB3 Signaling",1.42,0.087,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["ErbB2-ErbB3 Signaling",1.42,0.087,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["ErbB2-ErbB3 Signaling",1.42,0.087,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["ErbB2-ErbB3 Signaling",1.42,0.087,"NaN","PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["Endothelin-1 Signaling",1.41,0.0642,0,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Endothelin-1 Signaling",1.41,0.0642,0,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Endothelin-1 Signaling",1.41,0.0642,0,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Endothelin-1 Signaling",1.41,0.0642,0,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Endothelin-1 Signaling",1.41,0.0642,0,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Endothelin-1 Signaling",1.41,0.0642,0,"CASP2","caspase 2","Cytoplasm","peptidase",0.0015242294,0.0005334935,"down",1.3856739,-1.3856739,-0.47058776]
["Endothelin-1 Signaling",1.41,0.0642,0,"CASP1","caspase 1","Cytoplasm","peptidase",0.0010976536,0.00020770791,"down",1.8456633,-1.8456633,-0.88413936]
["Endothelin-1 Signaling",1.41,0.0642,0,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Endothelin-1 Signaling",1.41,0.0642,0,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Endothelin-1 Signaling",1.41,0.0642,0,"PTGS2","prostaglandin-endoperoxide synthase 2","Cytoplasm","enzyme",0.0012584343,0.00031259237,"down",1.4767396,-1.4767396,-0.5624155]
["Endothelin-1 Signaling",1.41,0.0642,0,"ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["Endothelin-1 Signaling",1.41,0.0642,0,"PAFAH1B3","platelet activating factor acetylhydrolase 1b catalytic subunit 3","Cytoplasm","enzyme",0.0029175605,0.0017729017,"up",1.3077043,1.3077043,0.38703638]
["VEGF Family Ligand-Receptor Interactions",1.4,0.0795,0.378,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["VEGF Family Ligand-Receptor Interactions",1.4,0.0795,0.378,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["VEGF Family Ligand-Receptor Interactions",1.4,0.0795,0.378,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["VEGF Family Ligand-Receptor Interactions",1.4,0.0795,0.378,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["VEGF Family Ligand-Receptor Interactions",1.4,0.0795,0.378,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["VEGF Family Ligand-Receptor Interactions",1.4,0.0795,0.378,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["VEGF Family Ligand-Receptor Interactions",1.4,0.0795,0.378,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Cdc42 Signaling",1.4,0.0659,1.667,"ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["Cdc42 Signaling",1.4,0.0659,1.667,"CDC42BPA","CDC42 binding protein kinase alpha","Cytoplasm","kinase",0.01694084,0.0156203,"up",1.3157506,1.3157506,0.39588603]
["Cdc42 Signaling",1.4,0.0659,1.667,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Cdc42 Signaling",1.4,0.0659,1.667,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Cdc42 Signaling",1.4,0.0659,1.667,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["Cdc42 Signaling",1.4,0.0659,1.667,"WASL","Wiskott-Aldrich syndrome like","Cytoplasm","other",0.00040977335,6.54692e-06,"up",1.4019742,1.4019742,0.4874598]
["Cdc42 Signaling",1.4,0.0659,1.667,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Cdc42 Signaling",1.4,0.0659,1.667,"LIMK2","LIM domain kinase 2","Cytoplasm","kinase",0.0035328772,0.002318736,"up",1.3875531,1.3875531,0.47254297]
["Cdc42 Signaling",1.4,0.0659,1.667,"MYL6B","myosin light chain 6B","Cytoplasm","other",0.0037700427,0.0025393397,"up",1.3426967,1.3426967,0.4251334]
["Cdc42 Signaling",1.4,0.0659,1.667,"HLA-F","major histocompatibility complex, class I, F","Plasma Membrane","transmembrane receptor",0.00070557836,5.4619704e-05,"up",1.622745,1.622745,0.6984363]
["Cdc42 Signaling",1.4,0.0659,1.667,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["FcγRIIB Signaling in B Lymphocytes",1.38,0.0943,0.447,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["FcγRIIB Signaling in B Lymphocytes",1.38,0.0943,0.447,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["FcγRIIB Signaling in B Lymphocytes",1.38,0.0943,0.447,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["FcγRIIB Signaling in B Lymphocytes",1.38,0.0943,0.447,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["FcγRIIB Signaling in B Lymphocytes",1.38,0.0943,0.447,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Caveolar-mediated Endocytosis Signaling",1.37,0.0845,"NaN","ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["Caveolar-mediated Endocytosis Signaling",1.37,0.0845,"NaN","CD55","CD55 molecule (Cromer blood group)","Plasma Membrane","other",0.0022323814,0.0011921417,"down",1.4334465,-1.4334465,-0.5194881]
["Caveolar-mediated Endocytosis Signaling",1.37,0.0845,"NaN","ARCN1","archain 1","Cytoplasm","other",0.0018968133,0.0008895908,"up",1.3269843,1.3269843,0.40815127]
["Caveolar-mediated Endocytosis Signaling",1.37,0.0845,"NaN","RAB5A","RAB5A, member RAS oncogene family","Cytoplasm","enzyme",0.001415604,0.00043224083,"up",1.4926699,1.4926699,0.57789516]
["Caveolar-mediated Endocytosis Signaling",1.37,0.0845,"NaN","CAV1","caveolin 1","Plasma Membrane","transmembrane receptor",0.0014512807,0.00046188477,"up",1.5792397,1.5792397,0.6592302]
["Caveolar-mediated Endocytosis Signaling",1.37,0.0845,"NaN","ITGB8","integrin subunit beta 8","Plasma Membrane","other",0.0039384346,0.0026866843,"up",1.8310404,1.8310404,0.8726636]
["CD28 Signaling in T Helper Cells",1.35,0.0698,1,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["CD28 Signaling in T Helper Cells",1.35,0.0698,1,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["CD28 Signaling in T Helper Cells",1.35,0.0698,1,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["CD28 Signaling in T Helper Cells",1.35,0.0698,1,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["CD28 Signaling in T Helper Cells",1.35,0.0698,1,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["CD28 Signaling in T Helper Cells",1.35,0.0698,1,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["CD28 Signaling in T Helper Cells",1.35,0.0698,1,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["CD28 Signaling in T Helper Cells",1.35,0.0698,1,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["CD28 Signaling in T Helper Cells",1.35,0.0698,1,"ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["D-myo-inositol (1,4,5,6)-Tetrakisphosphate Biosynthesis",1.35,0.0698,"NaN","MTMR9","myotubularin related protein 9","Cytoplasm","phosphatase",0.0011428653,0.0002310908,"down",1.3561463,-1.3561463,-0.43951285]
["D-myo-inositol (1,4,5,6)-Tetrakisphosphate Biosynthesis",1.35,0.0698,"NaN","NUDT12","nudix hydrolase 12","Cytoplasm","phosphatase",0.0015242294,0.00053365715,"up",1.4112375,1.4112375,0.49696076]
["D-myo-inositol (1,4,5,6)-Tetrakisphosphate Biosynthesis",1.35,0.0698,"NaN","PPM1H","protein phosphatase, Mg2+/Mn2+ dependent 1H","Other","phosphatase",0.001395873,0.00041960352,"up",1.558836,1.558836,0.64046913]
["D-myo-inositol (1,4,5,6)-Tetrakisphosphate Biosynthesis",1.35,0.0698,"NaN","PPFIA3","PTPRF interacting protein alpha 3","Plasma Membrane","phosphatase",0.0022608375,0.0012176248,"up",1.4032409,1.4032409,0.4887627]
["D-myo-inositol (1,4,5,6)-Tetrakisphosphate Biosynthesis",1.35,0.0698,"NaN","PPM1F","protein phosphatase, Mg2+/Mn2+ dependent 1F","Cytoplasm","phosphatase",0.0016241793,0.0006365216,"down",1.3318694,-1.3318694,-0.41345257]
["D-myo-inositol (1,4,5,6)-Tetrakisphosphate Biosynthesis",1.35,0.0698,"NaN","MTMR2","myotubularin related protein 2","Cytoplasm","phosphatase",0.001395873,0.000419132,"up",1.3830658,1.3830658,0.46786982]
["D-myo-inositol (1,4,5,6)-Tetrakisphosphate Biosynthesis",1.35,0.0698,"NaN","STYXL1","serine/threonine/tyrosine interacting-like 1","Cytoplasm","phosphatase",0.0017035499,0.00070178014,"up",1.310616,1.310616,0.39024505]
["D-myo-inositol (1,4,5,6)-Tetrakisphosphate Biosynthesis",1.35,0.0698,"NaN","STYX","serine/threonine/tyrosine interacting protein","Cytoplasm","phosphatase",0.0006217929,2.9874785e-05,"up",1.4957032,1.4957032,0.58082396]
["D-myo-inositol (1,4,5,6)-Tetrakisphosphate Biosynthesis",1.35,0.0698,"NaN","PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["D-myo-inositol (3,4,5,6)-tetrakisphosphate Biosynthesis",1.35,0.0698,"NaN","MTMR9","myotubularin related protein 9","Cytoplasm","phosphatase",0.0011428653,0.0002310908,"down",1.3561463,-1.3561463,-0.43951285]
["D-myo-inositol (3,4,5,6)-tetrakisphosphate Biosynthesis",1.35,0.0698,"NaN","NUDT12","nudix hydrolase 12","Cytoplasm","phosphatase",0.0015242294,0.00053365715,"up",1.4112375,1.4112375,0.49696076]
["D-myo-inositol (3,4,5,6)-tetrakisphosphate Biosynthesis",1.35,0.0698,"NaN","PPM1H","protein phosphatase, Mg2+/Mn2+ dependent 1H","Other","phosphatase",0.001395873,0.00041960352,"up",1.558836,1.558836,0.64046913]
["D-myo-inositol (3,4,5,6)-tetrakisphosphate Biosynthesis",1.35,0.0698,"NaN","PPFIA3","PTPRF interacting protein alpha 3","Plasma Membrane","phosphatase",0.0022608375,0.0012176248,"up",1.4032409,1.4032409,0.4887627]
["D-myo-inositol (3,4,5,6)-tetrakisphosphate Biosynthesis",1.35,0.0698,"NaN","PPM1F","protein phosphatase, Mg2+/Mn2+ dependent 1F","Cytoplasm","phosphatase",0.0016241793,0.0006365216,"down",1.3318694,-1.3318694,-0.41345257]
["D-myo-inositol (3,4,5,6)-tetrakisphosphate Biosynthesis",1.35,0.0698,"NaN","MTMR2","myotubularin related protein 2","Cytoplasm","phosphatase",0.001395873,0.000419132,"up",1.3830658,1.3830658,0.46786982]
["D-myo-inositol (3,4,5,6)-tetrakisphosphate Biosynthesis",1.35,0.0698,"NaN","STYXL1","serine/threonine/tyrosine interacting-like 1","Cytoplasm","phosphatase",0.0017035499,0.00070178014,"up",1.310616,1.310616,0.39024505]
["D-myo-inositol (3,4,5,6)-tetrakisphosphate Biosynthesis",1.35,0.0698,"NaN","STYX","serine/threonine/tyrosine interacting protein","Cytoplasm","phosphatase",0.0006217929,2.9874785e-05,"up",1.4957032,1.4957032,0.58082396]
["D-myo-inositol (3,4,5,6)-tetrakisphosphate Biosynthesis",1.35,0.0698,"NaN","PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["Protein Ubiquitination Pathway",1.35,0.0588,"NaN","PSMB9","proteasome subunit beta 9","Cytoplasm","peptidase",0.0015865989,0.0005862627,"up",1.5161694,1.5161694,0.60043097]
["Protein Ubiquitination Pathway",1.35,0.0588,"NaN","NEDD4","neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase","Cytoplasm","enzyme",0.00067191356,4.1885378e-05,"up",2.6203134,2.6203134,1.3897394]
["Protein Ubiquitination Pathway",1.35,0.0588,"NaN","USP12","ubiquitin specific peptidase 12","Cytoplasm","peptidase",0.0013628498,0.00038338048,"down",1.603109,-1.603109,-0.6808725]
["Protein Ubiquitination Pathway",1.35,0.0588,"NaN","DNAJC6","DnaJ heat shock protein family (Hsp40) member C6","Cytoplasm","other",0.00471877,0.0034019037,"up",1.5755986,1.5755986,0.6559]
["Protein Ubiquitination Pathway",1.35,0.0588,"NaN","CDC23","cell division cycle 23","Nucleus","enzyme",0.001459056,0.0004736629,"down",1.4613066,-1.4613066,-0.54725885]
["Protein Ubiquitination Pathway",1.35,0.0588,"NaN","HSPA5","heat shock protein family A (Hsp70) member 5","Cytoplasm","enzyme",0.007907775,0.006494456,"down",1.3693051,-1.3693051,-0.45344397]
["Protein Ubiquitination Pathway",1.35,0.0588,"NaN","SKP2","S-phase kinase-associated protein 2, E3 ubiquitin protein ligase","Nucleus","enzyme",0.0014867174,0.000499228,"up",1.348095,1.348095,0.4309222]
["Protein Ubiquitination Pathway",1.35,0.0588,"NaN","USP31","ubiquitin specific peptidase 31","Nucleus","peptidase",0.001612635,0.00061324576,"up",1.3984357,1.3984357,0.4838139]
["Protein Ubiquitination Pathway",1.35,0.0588,"NaN","USP13","ubiquitin specific peptidase 13 (isopeptidase T-3)","Other","peptidase",0.0008942897,0.00011043223,"up",1.4320148,1.4320148,0.51804644]
["Protein Ubiquitination Pathway",1.35,0.0588,"NaN","USP42","ubiquitin specific peptidase 42","Other","peptidase",0.0005464768,1.3414806e-05,"up",1.5076083,1.5076083,0.5922616]
["Protein Ubiquitination Pathway",1.35,0.0588,"NaN","DNAJC18","DnaJ heat shock protein family (Hsp40) member C18","Other","enzyme",0.004395149,0.0030934683,"up",1.7337146,1.7337146,0.7938664]
["Protein Ubiquitination Pathway",1.35,0.0588,"NaN","HSP90AA1","heat shock protein 90kDa alpha family class A member 1","Cytoplasm","enzyme",0.0005783946,2.0937947e-05,"up",1.5556576,1.5556576,0.63752455]
["Protein Ubiquitination Pathway",1.35,0.0588,"NaN","SMURF2","SMAD specific E3 ubiquitin protein ligase 2","Cytoplasm","enzyme",0.0017505207,0.0007564604,"up",1.4427907,1.4427907,0.52886206]
["Protein Ubiquitination Pathway",1.35,0.0588,"NaN","DNAJB1","DnaJ heat shock protein family (Hsp40) member B1","Nucleus","other",0.0012010665,0.0002643174,"down",2.432129,-2.432129,-1.2822196]
["Protein Ubiquitination Pathway",1.35,0.0588,"NaN","DNAJB6","DnaJ heat shock protein family (Hsp40) member B6","Nucleus","transcription regulator",0.0016760693,0.00068303355,"up",2.0961676,2.0961676,1.067754]
["Role of MAPK Signaling in the Pathogenesis of Influenza",1.34,0.0833,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Role of MAPK Signaling in the Pathogenesis of Influenza",1.34,0.0833,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Role of MAPK Signaling in the Pathogenesis of Influenza",1.34,0.0833,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Role of MAPK Signaling in the Pathogenesis of Influenza",1.34,0.0833,"NaN","PTGS2","prostaglandin-endoperoxide synthase 2","Cytoplasm","enzyme",0.0012584343,0.00031259237,"down",1.4767396,-1.4767396,-0.5624155]
["Role of MAPK Signaling in the Pathogenesis of Influenza",1.34,0.0833,"NaN","ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["Role of MAPK Signaling in the Pathogenesis of Influenza",1.34,0.0833,"NaN","PAFAH1B3","platelet activating factor acetylhydrolase 1b catalytic subunit 3","Cytoplasm","enzyme",0.0029175605,0.0017729017,"up",1.3077043,1.3077043,0.38703638]
["GM-CSF Signaling",1.32,0.0822,0.816,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["GM-CSF Signaling",1.32,0.0822,0.816,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["GM-CSF Signaling",1.32,0.0822,0.816,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["GM-CSF Signaling",1.32,0.0822,0.816,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["GM-CSF Signaling",1.32,0.0822,0.816,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["GM-CSF Signaling",1.32,0.0822,0.816,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Embryonic Stem Cell Differentiation into Cardiac Lineages",1.32,0.2,"NaN","SOX2","SRY-box 2","Nucleus","transcription regulator",0.0013107243,0.00034832067,"up",1.4385506,1.4385506,0.52461594]
["Embryonic Stem Cell Differentiation into Cardiac Lineages",1.32,0.2,"NaN","MESP1","mesoderm posterior bHLH transcription factor 1","Nucleus","transcription regulator",0.0022333448,0.0011936179,"down",1.4486951,-1.4486951,-0.5347539]
["Glycine Betaine Degradation",1.32,0.2,"NaN","SHMT1","serine hydroxymethyltransferase 1","Cytoplasm","enzyme",0.0008942897,0.000111482994,"up",1.4391686,1.4391686,0.5252356]
["Glycine Betaine Degradation",1.32,0.2,"NaN","SHMT2","serine hydroxymethyltransferase 2","Cytoplasm","enzyme",0.0022647758,0.0012213683,"down",1.6496395,-1.6496395,-0.72215074]
["RhoGDI Signaling",1.3,0.0636,-0.632,"ROCK2","Rho associated coiled-coil containing protein kinase 2","Cytoplasm","kinase",0.0010184328,0.00016622998,"up",1.3479002,1.3479002,0.43071362]
["RhoGDI Signaling",1.3,0.0636,-0.632,"ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["RhoGDI Signaling",1.3,0.0636,-0.632,"GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["RhoGDI Signaling",1.3,0.0636,-0.632,"CDH2","cadherin 2","Plasma Membrane","other",0.001091852,0.00020167766,"up",1.3591936,1.3591936,0.44275093]
["RhoGDI Signaling",1.3,0.0636,-0.632,"CDH1","cadherin 1","Plasma Membrane","other",0.0017019173,0.0006999703,"up",1.452055,1.452055,0.5380961]
["RhoGDI Signaling",1.3,0.0636,-0.632,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["RhoGDI Signaling",1.3,0.0636,-0.632,"WASL","Wiskott-Aldrich syndrome like","Cytoplasm","other",0.00040977335,6.54692e-06,"up",1.4019742,1.4019742,0.4874598]
["RhoGDI Signaling",1.3,0.0636,-0.632,"RHOU","ras homolog family member U","Cytoplasm","enzyme",0.0009194498,0.00012193339,"down",1.7715495,-1.7715495,-0.82501173]
["RhoGDI Signaling",1.3,0.0636,-0.632,"ARHGAP12","Rho GTPase activating protein 12","Cytoplasm","other",0.009885796,0.008399947,"down",1.4160204,-1.4160204,-0.501842]
["RhoGDI Signaling",1.3,0.0636,-0.632,"LIMK2","LIM domain kinase 2","Cytoplasm","kinase",0.0035328772,0.002318736,"up",1.3875531,1.3875531,0.47254297]
["RhoGDI Signaling",1.3,0.0636,-0.632,"MYL6B","myosin light chain 6B","Cytoplasm","other",0.0037700427,0.0025393397,"up",1.3426967,1.3426967,0.4251334]
["PPAR Signaling",1.29,0.0753,-0.378,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["PPAR Signaling",1.29,0.0753,-0.378,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["PPAR Signaling",1.29,0.0753,-0.378,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["PPAR Signaling",1.29,0.0753,-0.378,"MED1","mediator complex subunit 1","Nucleus","transcription regulator",0.007830824,0.006407651,"down",1.3726159,-1.3726159,-0.456928]
["PPAR Signaling",1.29,0.0753,-0.378,"HSP90AA1","heat shock protein 90kDa alpha family class A member 1","Cytoplasm","enzyme",0.0005783946,2.0937947e-05,"up",1.5556576,1.5556576,0.63752455]
["PPAR Signaling",1.29,0.0753,-0.378,"PTGS2","prostaglandin-endoperoxide synthase 2","Cytoplasm","enzyme",0.0012584343,0.00031259237,"down",1.4767396,-1.4767396,-0.5624155]
["PPAR Signaling",1.29,0.0753,-0.378,"CITED2","Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2","Nucleus","transcription regulator",0.010849081,0.009426419,"up",1.4059179,1.4059179,0.49151233]
["IL-22 Signaling",1.27,0.125,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["IL-22 Signaling",1.27,0.125,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["IL-22 Signaling",1.27,0.125,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Estrogen-mediated S-phase Entry",1.27,0.125,"NaN","CCNE1","cyclin E1","Nucleus","transcription regulator",0.0013342145,0.00036659295,"down",2.6488216,-2.6488216,-1.4053507]
["Estrogen-mediated S-phase Entry",1.27,0.125,"NaN","CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["Estrogen-mediated S-phase Entry",1.27,0.125,"NaN","SKP2","S-phase kinase-associated protein 2, E3 ubiquitin protein ligase","Nucleus","enzyme",0.0014867174,0.000499228,"up",1.348095,1.348095,0.4309222]
["Clathrin-mediated Endocytosis Signaling",1.27,0.0609,"NaN","ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["Clathrin-mediated Endocytosis Signaling",1.27,0.0609,"NaN","MET","MET proto-oncogene, receptor tyrosine kinase","Plasma Membrane","kinase",0.0008691947,0.00010051858,"up",1.5833938,1.5833938,0.66302013]
["Clathrin-mediated Endocytosis Signaling",1.27,0.0609,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Clathrin-mediated Endocytosis Signaling",1.27,0.0609,"NaN","RAB5A","RAB5A, member RAS oncogene family","Cytoplasm","enzyme",0.001415604,0.00043224083,"up",1.4926699,1.4926699,0.57789516]
["Clathrin-mediated Endocytosis Signaling",1.27,0.0609,"NaN","ARRB1","arrestin beta 1","Cytoplasm","other",0.0032341068,0.0020446463,"up",1.4974334,1.4974334,0.5824919]
["Clathrin-mediated Endocytosis Signaling",1.27,0.0609,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Clathrin-mediated Endocytosis Signaling",1.27,0.0609,"NaN","CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["Clathrin-mediated Endocytosis Signaling",1.27,0.0609,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Clathrin-mediated Endocytosis Signaling",1.27,0.0609,"NaN","WASL","Wiskott-Aldrich syndrome like","Cytoplasm","other",0.00040977335,6.54692e-06,"up",1.4019742,1.4019742,0.4874598]
["Clathrin-mediated Endocytosis Signaling",1.27,0.0609,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Clathrin-mediated Endocytosis Signaling",1.27,0.0609,"NaN","ITGB8","integrin subunit beta 8","Plasma Membrane","other",0.0039384346,0.0026866843,"up",1.8310404,1.8310404,0.8726636]
["Clathrin-mediated Endocytosis Signaling",1.27,0.0609,"NaN","MYO1E","myosin IE","Cytoplasm","enzyme",0.001979921,0.0009788757,"up",1.3184209,1.3184209,0.398811]
["Regulation of Cellular Mechanics by Calpain Protease",1.26,0.0877,"NaN","ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["Regulation of Cellular Mechanics by Calpain Protease",1.26,0.0877,"NaN","CCNE1","cyclin E1","Nucleus","transcription regulator",0.0013342145,0.00036659295,"down",2.6488216,-2.6488216,-1.4053507]
["Regulation of Cellular Mechanics by Calpain Protease",1.26,0.0877,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Regulation of Cellular Mechanics by Calpain Protease",1.26,0.0877,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Regulation of Cellular Mechanics by Calpain Protease",1.26,0.0877,"NaN","CDK6","cyclin-dependent kinase 6","Nucleus","kinase",0.0011555209,0.0002428485,"down",1.6726129,-1.6726129,-0.7421036]
["Neuropathic Pain Signaling In Dorsal Horn Neurons",1.26,0.0702,0.707,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Neuropathic Pain Signaling In Dorsal Horn Neurons",1.26,0.0702,0.707,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Neuropathic Pain Signaling In Dorsal Horn Neurons",1.26,0.0702,0.707,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Neuropathic Pain Signaling In Dorsal Horn Neurons",1.26,0.0702,0.707,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Neuropathic Pain Signaling In Dorsal Horn Neurons",1.26,0.0702,0.707,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Neuropathic Pain Signaling In Dorsal Horn Neurons",1.26,0.0702,0.707,"PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Neuropathic Pain Signaling In Dorsal Horn Neurons",1.26,0.0702,0.707,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Neuropathic Pain Signaling In Dorsal Horn Neurons",1.26,0.0702,0.707,"ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["Role of PI3K/AKT Signaling in the Pathogenesis of Influenza",1.25,0.0789,0.816,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Role of PI3K/AKT Signaling in the Pathogenesis of Influenza",1.25,0.0789,0.816,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Role of PI3K/AKT Signaling in the Pathogenesis of Influenza",1.25,0.0789,0.816,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Role of PI3K/AKT Signaling in the Pathogenesis of Influenza",1.25,0.0789,0.816,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Role of PI3K/AKT Signaling in the Pathogenesis of Influenza",1.25,0.0789,0.816,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Role of PI3K/AKT Signaling in the Pathogenesis of Influenza",1.25,0.0789,0.816,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["IL-17A Signaling in Gastric Cells",1.22,0.12,"NaN","CXCL8","C-X-C motif chemokine ligand 8","Extracellular Space","cytokine",0.0011259156,0.00022286079,"down",1.5851029,-1.5851029,-0.66457653]
["IL-17A Signaling in Gastric Cells",1.22,0.12,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["IL-17A Signaling in Gastric Cells",1.22,0.12,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["p38 MAPK Signaling",1.21,0.0684,0,"TRADD","TNFRSF1A associated via death domain","Cytoplasm","other",0.0016301863,0.0006398275,"up",1.3732907,1.3732907,0.457637]
["p38 MAPK Signaling",1.21,0.0684,0,"TGFBR1","transforming growth factor beta receptor 1","Plasma Membrane","kinase",0.0008942897,0.00011058827,"up",1.5758384,1.5758384,0.65611964]
["p38 MAPK Signaling",1.21,0.0684,0,"ATF1","activating transcription factor 1","Nucleus","transcription regulator",0.0070709703,0.005685401,"down",1.3784643,-1.3784643,-0.46306193]
["p38 MAPK Signaling",1.21,0.0684,0,"MEF2D","myocyte enhancer factor 2D","Nucleus","transcription regulator",0.0006217929,3.203251e-05,"down",1.3555743,-1.3555743,-0.43890414]
["p38 MAPK Signaling",1.21,0.0684,0,"RPS6KB2","ribosomal protein S6 kinase B2","Cytoplasm","kinase",0.0016431456,0.0006520507,"down",1.986918,-1.986918,-0.9905323]
["p38 MAPK Signaling",1.21,0.0684,0,"MEF2A","myocyte enhancer factor 2A","Nucleus","transcription regulator",0.015937602,0.014585446,"down",1.3274704,-1.3274704,-0.40867972]
["p38 MAPK Signaling",1.21,0.0684,0,"EEF2K","eukaryotic elongation factor 2 kinase","Cytoplasm","kinase",0.0013760548,0.00039997842,"down",1.5132525,-1.5132525,-0.59765273]
["p38 MAPK Signaling",1.21,0.0684,0,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["NF-κB Signaling",1.21,0.0611,0.905,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["NF-κB Signaling",1.21,0.0611,0.905,"TRADD","TNFRSF1A associated via death domain","Cytoplasm","other",0.0016301863,0.0006398275,"up",1.3732907,1.3732907,0.457637]
["NF-κB Signaling",1.21,0.0611,0.905,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["NF-κB Signaling",1.21,0.0611,0.905,"TGFBR1","transforming growth factor beta receptor 1","Plasma Membrane","kinase",0.0008942897,0.00011058827,"up",1.5758384,1.5758384,0.65611964]
["NF-κB Signaling",1.21,0.0611,0.905,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["NF-κB Signaling",1.21,0.0611,0.905,"MYD88","myeloid differentiation primary response 88","Plasma Membrane","other",0.0019091989,0.0009046913,"down",1.3930262,-1.3930262,-0.47822243]
["NF-κB Signaling",1.21,0.0611,0.905,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["NF-κB Signaling",1.21,0.0611,0.905,"IGF1R","insulin like growth factor 1 receptor","Plasma Membrane","transmembrane receptor",0.0016147236,0.0006161828,"up",1.8701973,1.8701973,0.90319043]
["NF-κB Signaling",1.21,0.0611,0.905,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["NF-κB Signaling",1.21,0.0611,0.905,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["NF-κB Signaling",1.21,0.0611,0.905,"TBK1","TANK binding kinase 1","Cytoplasm","kinase",0.005976595,0.004633019,"down",1.3411525,-1.3411525,-0.42347333]
["Role of BRCA1 in DNA Damage Response",1.2,0.0769,0,"PBRM1","polybromo 1","Nucleus","other",0.0055692703,0.0042261216,"down",1.4428215,-1.4428215,-0.5288928]
["Role of BRCA1 in DNA Damage Response",1.2,0.0769,0,"ATF1","activating transcription factor 1","Nucleus","transcription regulator",0.0070709703,0.005685401,"down",1.3784643,-1.3784643,-0.46306193]
["Role of BRCA1 in DNA Damage Response",1.2,0.0769,0,"CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["Role of BRCA1 in DNA Damage Response",1.2,0.0769,0,"RFC1","replication factor C subunit 1","Nucleus","transcription regulator",0.011040431,0.009618774,"up",1.3221459,1.3221459,0.4028814]
["Role of BRCA1 in DNA Damage Response",1.2,0.0769,0,"CHEK2","checkpoint kinase 2","Nucleus","kinase",0.0028598784,0.0017272087,"up",1.3150214,1.3150214,0.39508626]
["Role of BRCA1 in DNA Damage Response",1.2,0.0769,0,"CHEK1","checkpoint kinase 1","Nucleus","kinase",0.0010877973,0.00019520131,"up",1.4226359,1.4226359,0.5085665]
["Thrombin Signaling",1.19,0.0591,0.905,"ROCK2","Rho associated coiled-coil containing protein kinase 2","Cytoplasm","kinase",0.0010184328,0.00016622998,"up",1.3479002,1.3479002,0.43071362]
["Thrombin Signaling",1.19,0.0591,0.905,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Thrombin Signaling",1.19,0.0591,0.905,"GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["Thrombin Signaling",1.19,0.0591,0.905,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Thrombin Signaling",1.19,0.0591,0.905,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Thrombin Signaling",1.19,0.0591,0.905,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Thrombin Signaling",1.19,0.0591,0.905,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Thrombin Signaling",1.19,0.0591,0.905,"RHOU","ras homolog family member U","Cytoplasm","enzyme",0.0009194498,0.00012193339,"down",1.7715495,-1.7715495,-0.82501173]
["Thrombin Signaling",1.19,0.0591,0.905,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Thrombin Signaling",1.19,0.0591,0.905,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Thrombin Signaling",1.19,0.0591,0.905,"MYL6B","myosin light chain 6B","Cytoplasm","other",0.0037700427,0.0025393397,"up",1.3426967,1.3426967,0.4251334]
["Thrombin Signaling",1.19,0.0591,0.905,"ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["Dermatan Sulfate Biosynthesis",1.19,0.0833,"NaN","CHST2","carbohydrate sulfotransferase 2","Cytoplasm","enzyme",0.0010089864,0.0001642536,"down",1.9582679,-1.9582679,-0.96957815]
["Dermatan Sulfate Biosynthesis",1.19,0.0833,"NaN","CHST7","carbohydrate sulfotransferase 7","Cytoplasm","enzyme",0.001091852,0.00020487046,"up",1.4233469,1.4233469,0.5092873]
["Dermatan Sulfate Biosynthesis",1.19,0.0833,"NaN","GXYLT1","glucoside xylosyltransferase 1","Cytoplasm","enzyme",0.0016147236,0.00061580446,"up",1.7539235,1.7539235,0.81058586]
["Dermatan Sulfate Biosynthesis",1.19,0.0833,"NaN","DSEL","dermatan sulfate epimerase-like","Extracellular Space","enzyme",0.00040977335,6.3851976e-06,"down",2.2434306,-2.2434306,-1.1657065]
["Dermatan Sulfate Biosynthesis",1.19,0.0833,"NaN","DSE","dermatan sulfate epimerase","Cytoplasm","enzyme",0.0019608224,0.00096280355,"down",1.410439,-1.410439,-0.4961443]
["Regulation of IL-2 Expression in Activated and Anergic T Lymphocytes",1.18,0.0759,"NaN","IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["Regulation of IL-2 Expression in Activated and Anergic T Lymphocytes",1.18,0.0759,"NaN","TGFBR1","transforming growth factor beta receptor 1","Plasma Membrane","kinase",0.0008942897,0.00011058827,"up",1.5758384,1.5758384,0.65611964]
["Regulation of IL-2 Expression in Activated and Anergic T Lymphocytes",1.18,0.0759,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Regulation of IL-2 Expression in Activated and Anergic T Lymphocytes",1.18,0.0759,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Regulation of IL-2 Expression in Activated and Anergic T Lymphocytes",1.18,0.0759,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Regulation of IL-2 Expression in Activated and Anergic T Lymphocytes",1.18,0.0759,"NaN","TOB1","transducer of ERBB2, 1","Nucleus","transcription regulator",0.0027434009,0.001628082,"down",1.7747058,-1.7747058,-0.82757986]
["Fc Epsilon RI Signaling",1.18,0.0672,0.707,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Fc Epsilon RI Signaling",1.18,0.0672,0.707,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Fc Epsilon RI Signaling",1.18,0.0672,0.707,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Fc Epsilon RI Signaling",1.18,0.0672,0.707,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Fc Epsilon RI Signaling",1.18,0.0672,0.707,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Fc Epsilon RI Signaling",1.18,0.0672,0.707,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Fc Epsilon RI Signaling",1.18,0.0672,0.707,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Fc Epsilon RI Signaling",1.18,0.0672,0.707,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Role of p14/p19ARF in Tumor Suppression",1.16,0.093,0,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Role of p14/p19ARF in Tumor Suppression",1.16,0.093,0,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Role of p14/p19ARF in Tumor Suppression",1.16,0.093,0,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Role of p14/p19ARF in Tumor Suppression",1.16,0.093,0,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["iCOS-iCOSL Signaling in T Helper Cells",1.16,0.0667,1.134,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["iCOS-iCOSL Signaling in T Helper Cells",1.16,0.0667,1.134,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["iCOS-iCOSL Signaling in T Helper Cells",1.16,0.0667,1.134,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["iCOS-iCOSL Signaling in T Helper Cells",1.16,0.0667,1.134,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["iCOS-iCOSL Signaling in T Helper Cells",1.16,0.0667,1.134,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["iCOS-iCOSL Signaling in T Helper Cells",1.16,0.0667,1.134,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["iCOS-iCOSL Signaling in T Helper Cells",1.16,0.0667,1.134,"ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["iCOS-iCOSL Signaling in T Helper Cells",1.16,0.0667,1.134,"PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["CREB Signaling in Neurons",1.15,0.0598,1.265,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["CREB Signaling in Neurons",1.15,0.0598,1.265,"GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["CREB Signaling in Neurons",1.15,0.0598,1.265,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["CREB Signaling in Neurons",1.15,0.0598,1.265,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["CREB Signaling in Neurons",1.15,0.0598,1.265,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["CREB Signaling in Neurons",1.15,0.0598,1.265,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["CREB Signaling in Neurons",1.15,0.0598,1.265,"PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["CREB Signaling in Neurons",1.15,0.0598,1.265,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["CREB Signaling in Neurons",1.15,0.0598,1.265,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["CREB Signaling in Neurons",1.15,0.0598,1.265,"ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["CREB Signaling in Neurons",1.15,0.0598,1.265,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["Epoxysqualene Biosynthesis",1.15,0.5,"NaN","SQLE","squalene epoxidase","Cytoplasm","enzyme",0.00069462875,4.9444014e-05,"up",1.517981,1.517981,0.6021538]
["Glutamine Degradation I",1.15,0.5,"NaN","GLS","glutaminase","Cytoplasm","enzyme",0.0045107757,0.0032061748,"up",1.6075542,1.6075542,0.6848674]
["Cell Cycle Control of Chromosomal Replication",1.14,0.111,"NaN","MCM6","minichromosome maintenance complex component 6","Nucleus","enzyme",0.00036445798,4.845088e-06,"up",1.9943935,1.9943935,0.99595004]
["Cell Cycle Control of Chromosomal Replication",1.14,0.111,"NaN","CDK6","cyclin-dependent kinase 6","Nucleus","kinase",0.0011555209,0.0002428485,"down",1.6726129,-1.6726129,-0.7421036]
["Cell Cycle Control of Chromosomal Replication",1.14,0.111,"NaN","CHEK2","checkpoint kinase 2","Nucleus","kinase",0.0028598784,0.0017272087,"up",1.3150214,1.3150214,0.39508626]
["phagosome formation",1.13,0.0656,"NaN","ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["phagosome formation",1.13,0.0656,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["phagosome formation",1.13,0.0656,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["phagosome formation",1.13,0.0656,"NaN","SCARA3","scavenger receptor class A member 3","Plasma Membrane","transmembrane receptor",0.0019320704,0.00092334545,"up",1.5431218,1.5431218,0.6258519]
["phagosome formation",1.13,0.0656,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["phagosome formation",1.13,0.0656,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["phagosome formation",1.13,0.0656,"NaN","RHOU","ras homolog family member U","Cytoplasm","enzyme",0.0009194498,0.00012193339,"down",1.7715495,-1.7715495,-0.82501173]
["phagosome formation",1.13,0.0656,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Cholesterol Biosynthesis I",1.11,0.154,"NaN","SQLE","squalene epoxidase","Cytoplasm","enzyme",0.00069462875,4.9444014e-05,"up",1.517981,1.517981,0.6021538]
["Cholesterol Biosynthesis I",1.11,0.154,"NaN","MSMO1","methylsterol monooxygenase 1","Cytoplasm","enzyme",0.0012443048,0.00030560244,"up",1.4843444,1.4843444,0.5698258]
["Mevalonate Pathway I",1.11,0.154,"NaN","PMVK","phosphomevalonate kinase","Cytoplasm","kinase",0.0015215367,0.0005270031,"down",1.3550662,-1.3550662,-0.4383633]
["Mevalonate Pathway I",1.11,0.154,"NaN","HMGCR","3-hydroxy-3-methylglutaryl-CoA reductase","Cytoplasm","enzyme",0.0014677041,0.00048228173,"up",1.3671681,1.3671681,0.4511906]
["Cholesterol Biosynthesis II (via 24,25-dihydrolanosterol)",1.11,0.154,"NaN","SQLE","squalene epoxidase","Cytoplasm","enzyme",0.00069462875,4.9444014e-05,"up",1.517981,1.517981,0.6021538]
["Cholesterol Biosynthesis II (via 24,25-dihydrolanosterol)",1.11,0.154,"NaN","MSMO1","methylsterol monooxygenase 1","Cytoplasm","enzyme",0.0012443048,0.00030560244,"up",1.4843444,1.4843444,0.5698258]
["Cholesterol Biosynthesis III (via Desmosterol)",1.11,0.154,"NaN","SQLE","squalene epoxidase","Cytoplasm","enzyme",0.00069462875,4.9444014e-05,"up",1.517981,1.517981,0.6021538]
["Cholesterol Biosynthesis III (via Desmosterol)",1.11,0.154,"NaN","MSMO1","methylsterol monooxygenase 1","Cytoplasm","enzyme",0.0012443048,0.00030560244,"up",1.4843444,1.4843444,0.5698258]
["IL-9 Signaling",1.11,0.0889,0,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["IL-9 Signaling",1.11,0.0889,0,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["IL-9 Signaling",1.11,0.0889,0,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["IL-9 Signaling",1.11,0.0889,0,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["VEGF Signaling",1.1,0.068,1.134,"ROCK2","Rho associated coiled-coil containing protein kinase 2","Cytoplasm","kinase",0.0010184328,0.00016622998,"up",1.3479002,1.3479002,0.43071362]
["VEGF Signaling",1.1,0.068,1.134,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["VEGF Signaling",1.1,0.068,1.134,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["VEGF Signaling",1.1,0.068,1.134,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["VEGF Signaling",1.1,0.068,1.134,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["VEGF Signaling",1.1,0.068,1.134,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["VEGF Signaling",1.1,0.068,1.134,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Cell Cycle: G1/S Checkpoint Regulation",1.09,0.0781,0,"HDAC6","histone deacetylase 6","Nucleus","transcription regulator",0.0060592825,0.0047327504,"up",1.6543902,1.6543902,0.7262995]
["Cell Cycle: G1/S Checkpoint Regulation",1.09,0.0781,0,"CCNE1","cyclin E1","Nucleus","transcription regulator",0.0013342145,0.00036659295,"down",2.6488216,-2.6488216,-1.4053507]
["Cell Cycle: G1/S Checkpoint Regulation",1.09,0.0781,0,"CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["Cell Cycle: G1/S Checkpoint Regulation",1.09,0.0781,0,"CDK6","cyclin-dependent kinase 6","Nucleus","kinase",0.0011555209,0.0002428485,"down",1.6726129,-1.6726129,-0.7421036]
["Cell Cycle: G1/S Checkpoint Regulation",1.09,0.0781,0,"SKP2","S-phase kinase-associated protein 2, E3 ubiquitin protein ligase","Nucleus","enzyme",0.0014867174,0.000499228,"up",1.348095,1.348095,0.4309222]
["3-phosphoinositide Degradation",1.08,0.0616,"NaN","MTMR9","myotubularin related protein 9","Cytoplasm","phosphatase",0.0011428653,0.0002310908,"down",1.3561463,-1.3561463,-0.43951285]
["3-phosphoinositide Degradation",1.08,0.0616,"NaN","NUDT12","nudix hydrolase 12","Cytoplasm","phosphatase",0.0015242294,0.00053365715,"up",1.4112375,1.4112375,0.49696076]
["3-phosphoinositide Degradation",1.08,0.0616,"NaN","PPM1H","protein phosphatase, Mg2+/Mn2+ dependent 1H","Other","phosphatase",0.001395873,0.00041960352,"up",1.558836,1.558836,0.64046913]
["3-phosphoinositide Degradation",1.08,0.0616,"NaN","PPFIA3","PTPRF interacting protein alpha 3","Plasma Membrane","phosphatase",0.0022608375,0.0012176248,"up",1.4032409,1.4032409,0.4887627]
["3-phosphoinositide Degradation",1.08,0.0616,"NaN","PPM1F","protein phosphatase, Mg2+/Mn2+ dependent 1F","Cytoplasm","phosphatase",0.0016241793,0.0006365216,"down",1.3318694,-1.3318694,-0.41345257]
["3-phosphoinositide Degradation",1.08,0.0616,"NaN","MTMR2","myotubularin related protein 2","Cytoplasm","phosphatase",0.001395873,0.000419132,"up",1.3830658,1.3830658,0.46786982]
["3-phosphoinositide Degradation",1.08,0.0616,"NaN","STYXL1","serine/threonine/tyrosine interacting-like 1","Cytoplasm","phosphatase",0.0017035499,0.00070178014,"up",1.310616,1.310616,0.39024505]
["3-phosphoinositide Degradation",1.08,0.0616,"NaN","STYX","serine/threonine/tyrosine interacting protein","Cytoplasm","phosphatase",0.0006217929,2.9874785e-05,"up",1.4957032,1.4957032,0.58082396]
["3-phosphoinositide Degradation",1.08,0.0616,"NaN","PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["Dermatan Sulfate Biosynthesis (Late Stages)",1.08,0.087,"NaN","CHST2","carbohydrate sulfotransferase 2","Cytoplasm","enzyme",0.0010089864,0.0001642536,"down",1.9582679,-1.9582679,-0.96957815]
["Dermatan Sulfate Biosynthesis (Late Stages)",1.08,0.087,"NaN","CHST7","carbohydrate sulfotransferase 7","Cytoplasm","enzyme",0.001091852,0.00020487046,"up",1.4233469,1.4233469,0.5092873]
["Dermatan Sulfate Biosynthesis (Late Stages)",1.08,0.087,"NaN","DSEL","dermatan sulfate epimerase-like","Extracellular Space","enzyme",0.00040977335,6.3851976e-06,"down",2.2434306,-2.2434306,-1.1657065]
["Dermatan Sulfate Biosynthesis (Late Stages)",1.08,0.087,"NaN","DSE","dermatan sulfate epimerase","Cytoplasm","enzyme",0.0019608224,0.00096280355,"down",1.410439,-1.410439,-0.4961443]
["D-myo-inositol-5-phosphate Metabolism",1.07,0.0612,"NaN","MTMR9","myotubularin related protein 9","Cytoplasm","phosphatase",0.0011428653,0.0002310908,"down",1.3561463,-1.3561463,-0.43951285]
["D-myo-inositol-5-phosphate Metabolism",1.07,0.0612,"NaN","NUDT12","nudix hydrolase 12","Cytoplasm","phosphatase",0.0015242294,0.00053365715,"up",1.4112375,1.4112375,0.49696076]
["D-myo-inositol-5-phosphate Metabolism",1.07,0.0612,"NaN","PPM1H","protein phosphatase, Mg2+/Mn2+ dependent 1H","Other","phosphatase",0.001395873,0.00041960352,"up",1.558836,1.558836,0.64046913]
["D-myo-inositol-5-phosphate Metabolism",1.07,0.0612,"NaN","PPFIA3","PTPRF interacting protein alpha 3","Plasma Membrane","phosphatase",0.0022608375,0.0012176248,"up",1.4032409,1.4032409,0.4887627]
["D-myo-inositol-5-phosphate Metabolism",1.07,0.0612,"NaN","PPM1F","protein phosphatase, Mg2+/Mn2+ dependent 1F","Cytoplasm","phosphatase",0.0016241793,0.0006365216,"down",1.3318694,-1.3318694,-0.41345257]
["D-myo-inositol-5-phosphate Metabolism",1.07,0.0612,"NaN","MTMR2","myotubularin related protein 2","Cytoplasm","phosphatase",0.001395873,0.000419132,"up",1.3830658,1.3830658,0.46786982]
["D-myo-inositol-5-phosphate Metabolism",1.07,0.0612,"NaN","STYXL1","serine/threonine/tyrosine interacting-like 1","Cytoplasm","phosphatase",0.0017035499,0.00070178014,"up",1.310616,1.310616,0.39024505]
["D-myo-inositol-5-phosphate Metabolism",1.07,0.0612,"NaN","STYX","serine/threonine/tyrosine interacting protein","Cytoplasm","phosphatase",0.0006217929,2.9874785e-05,"up",1.4957032,1.4957032,0.58082396]
["D-myo-inositol-5-phosphate Metabolism",1.07,0.0612,"NaN","PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["PI3K Signaling in B Lymphocytes",1.03,0.0625,1.414,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["PI3K Signaling in B Lymphocytes",1.03,0.0625,1.414,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["PI3K Signaling in B Lymphocytes",1.03,0.0625,1.414,"ATF1","activating transcription factor 1","Nucleus","transcription regulator",0.0070709703,0.005685401,"down",1.3784643,-1.3784643,-0.46306193]
["PI3K Signaling in B Lymphocytes",1.03,0.0625,1.414,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["PI3K Signaling in B Lymphocytes",1.03,0.0625,1.414,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["PI3K Signaling in B Lymphocytes",1.03,0.0625,1.414,"ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["PI3K Signaling in B Lymphocytes",1.03,0.0625,1.414,"PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["PI3K Signaling in B Lymphocytes",1.03,0.0625,1.414,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["EIF2 Signaling",1.03,0.0567,1.134,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["EIF2 Signaling",1.03,0.0567,1.134,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["EIF2 Signaling",1.03,0.0567,1.134,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["EIF2 Signaling",1.03,0.0567,1.134,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["EIF2 Signaling",1.03,0.0567,1.134,"PAIP1","poly(A) binding protein interacting protein 1","Cytoplasm","translation regulator",0.009647093,0.008172193,"up",1.4854679,1.4854679,0.5709174]
["EIF2 Signaling",1.03,0.0567,1.134,"EIF3J","eukaryotic translation initiation factor 3 subunit J","Cytoplasm","translation regulator",0.0008942897,0.00011461672,"down",1.5294574,-1.5294574,-0.61301994]
["EIF2 Signaling",1.03,0.0567,1.134,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["EIF2 Signaling",1.03,0.0567,1.134,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["EIF2 Signaling",1.03,0.0567,1.134,"RPS27A","ribosomal protein S27a","Cytoplasm","other",0.0033264575,0.002133116,"down",1.341015,-1.341015,-0.42332536]
["EIF2 Signaling",1.03,0.0567,1.134,"RPL31","ribosomal protein L31","Cytoplasm","other",0.0011370784,0.00022788574,"up",1.3928195,1.3928195,0.47800833]
["EIF2 Signaling",1.03,0.0567,1.134,"EIF3M","eukaryotic translation initiation factor 3 subunit M","Cytoplasm","other",0.0028598784,0.0017288154,"down",1.3275427,-1.3275427,-0.40875822]
["Relaxin Signaling",1.03,0.06,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Relaxin Signaling",1.03,0.06,"NaN","GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["Relaxin Signaling",1.03,0.06,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Relaxin Signaling",1.03,0.06,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Relaxin Signaling",1.03,0.06,"NaN","PDE3B","phosphodiesterase 3B","Cytoplasm","enzyme",0.0026252405,0.0015308249,"up",1.3255126,1.3255126,0.40655044]
["Relaxin Signaling",1.03,0.06,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Relaxin Signaling",1.03,0.06,"NaN","PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Relaxin Signaling",1.03,0.06,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Relaxin Signaling",1.03,0.06,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["GNRH Signaling",1.02,0.062,0.707,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["GNRH Signaling",1.02,0.062,0.707,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["GNRH Signaling",1.02,0.062,0.707,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["GNRH Signaling",1.02,0.062,0.707,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["GNRH Signaling",1.02,0.062,0.707,"PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["GNRH Signaling",1.02,0.062,0.707,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["GNRH Signaling",1.02,0.062,0.707,"ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["GNRH Signaling",1.02,0.062,0.707,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["Xenobiotic Metabolism Signaling",1.02,0.0524,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Xenobiotic Metabolism Signaling",1.02,0.0524,"NaN","MED1","mediator complex subunit 1","Nucleus","transcription regulator",0.007830824,0.006407651,"down",1.3726159,-1.3726159,-0.456928]
["Xenobiotic Metabolism Signaling",1.02,0.0524,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Xenobiotic Metabolism Signaling",1.02,0.0524,"NaN","CHST7","carbohydrate sulfotransferase 7","Cytoplasm","enzyme",0.001091852,0.00020487046,"up",1.4233469,1.4233469,0.5092873]
["Xenobiotic Metabolism Signaling",1.02,0.0524,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Xenobiotic Metabolism Signaling",1.02,0.0524,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Xenobiotic Metabolism Signaling",1.02,0.0524,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Xenobiotic Metabolism Signaling",1.02,0.0524,"NaN","GCLC","glutamate-cysteine ligase catalytic subunit","Cytoplasm","enzyme",0.001961328,0.0009667417,"down",1.3574277,-1.3574277,-0.44087538]
["Xenobiotic Metabolism Signaling",1.02,0.0524,"NaN","CHST2","carbohydrate sulfotransferase 2","Cytoplasm","enzyme",0.0010089864,0.0001642536,"down",1.9582679,-1.9582679,-0.96957815]
["Xenobiotic Metabolism Signaling",1.02,0.0524,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Xenobiotic Metabolism Signaling",1.02,0.0524,"NaN","GSTT2/GSTT2B","glutathione S-transferase theta 2 (gene/pseudogene)","Cytoplasm","enzyme",0.0011259156,0.00022387244,"up",1.4915317,1.4915317,0.5767947]
["Xenobiotic Metabolism Signaling",1.02,0.0524,"NaN","FTL","ferritin, light polypeptide","Cytoplasm","enzyme",0.0011684936,0.0002475878,"down",1.3095047,-1.3095047,-0.38902128]
["Xenobiotic Metabolism Signaling",1.02,0.0524,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Xenobiotic Metabolism Signaling",1.02,0.0524,"NaN","HSP90AA1","heat shock protein 90kDa alpha family class A member 1","Cytoplasm","enzyme",0.0005783946,2.0937947e-05,"up",1.5556576,1.5556576,0.63752455]
["Xenobiotic Metabolism Signaling",1.02,0.0524,"NaN","CITED2","Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2","Nucleus","transcription regulator",0.010849081,0.009426419,"up",1.4059179,1.4059179,0.49151233]
["TNFR1 Signaling",1,0.0816,0,"TRADD","TNFRSF1A associated via death domain","Cytoplasm","other",0.0016301863,0.0006398275,"up",1.3732907,1.3732907,0.457637]
["TNFR1 Signaling",1,0.0816,0,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["TNFR1 Signaling",1,0.0816,0,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["TNFR1 Signaling",1,0.0816,0,"CASP2","caspase 2","Cytoplasm","peptidase",0.0015242294,0.0005334935,"down",1.3856739,-1.3856739,-0.47058776]
["p70S6K Signaling",0.991,0.0611,0.707,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["p70S6K Signaling",0.991,0.0611,0.707,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["p70S6K Signaling",0.991,0.0611,0.707,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["p70S6K Signaling",0.991,0.0611,0.707,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["p70S6K Signaling",0.991,0.0611,0.707,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["p70S6K Signaling",0.991,0.0611,0.707,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["p70S6K Signaling",0.991,0.0611,0.707,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["p70S6K Signaling",0.991,0.0611,0.707,"EEF2K","eukaryotic elongation factor 2 kinase","Cytoplasm","kinase",0.0013760548,0.00039997842,"down",1.5132525,-1.5132525,-0.59765273]
["Glutathione Biosynthesis",0.981,0.333,"NaN","GCLC","glutamate-cysteine ligase catalytic subunit","Cytoplasm","enzyme",0.001961328,0.0009667417,"down",1.3574277,-1.3574277,-0.44087538]
["Methionine Salvage II (Mammalian)",0.981,0.333,"NaN","MTR","5-methyltetrahydrofolate-homocysteine methyltransferase","Cytoplasm","enzyme",0.0021334826,0.0011126819,"down",1.3912218,-1.3912218,-0.4763524]
["PDGF Signaling",0.971,0.0667,0,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["PDGF Signaling",0.971,0.0667,0,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["PDGF Signaling",0.971,0.0667,0,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["PDGF Signaling",0.971,0.0667,0,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["PDGF Signaling",0.971,0.0667,0,"CAV1","caveolin 1","Plasma Membrane","transmembrane receptor",0.0014512807,0.00046188477,"up",1.5792397,1.5792397,0.6592302]
["PDGF Signaling",0.971,0.0667,0,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Amyotrophic Lateral Sclerosis Signaling",0.971,0.0631,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Amyotrophic Lateral Sclerosis Signaling",0.971,0.0631,"NaN","RAB5A","RAB5A, member RAS oncogene family","Cytoplasm","enzyme",0.001415604,0.00043224083,"up",1.4926699,1.4926699,0.57789516]
["Amyotrophic Lateral Sclerosis Signaling",0.971,0.0631,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Amyotrophic Lateral Sclerosis Signaling",0.971,0.0631,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Amyotrophic Lateral Sclerosis Signaling",0.971,0.0631,"NaN","CASP1","caspase 1","Cytoplasm","peptidase",0.0010976536,0.00020770791,"down",1.8456633,-1.8456633,-0.88413936]
["Amyotrophic Lateral Sclerosis Signaling",0.971,0.0631,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Amyotrophic Lateral Sclerosis Signaling",0.971,0.0631,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["IL-1 Signaling",0.954,0.0659,1.342,"GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["IL-1 Signaling",0.954,0.0659,1.342,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["IL-1 Signaling",0.954,0.0659,1.342,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["IL-1 Signaling",0.954,0.0659,1.342,"MYD88","myeloid differentiation primary response 88","Plasma Membrane","other",0.0019091989,0.0009046913,"down",1.3930262,-1.3930262,-0.47822243]
["IL-1 Signaling",0.954,0.0659,1.342,"PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["IL-1 Signaling",0.954,0.0659,1.342,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["PPARα/RXRα Activation",0.953,0.0562,-0.378,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["PPARα/RXRα Activation",0.953,0.0562,-0.378,"TGFBR1","transforming growth factor beta receptor 1","Plasma Membrane","kinase",0.0008942897,0.00011058827,"up",1.5758384,1.5758384,0.65611964]
["PPARα/RXRα Activation",0.953,0.0562,-0.378,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["PPARα/RXRα Activation",0.953,0.0562,-0.378,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["PPARα/RXRα Activation",0.953,0.0562,-0.378,"MED1","mediator complex subunit 1","Nucleus","transcription regulator",0.007830824,0.006407651,"down",1.3726159,-1.3726159,-0.456928]
["PPARα/RXRα Activation",0.953,0.0562,-0.378,"LPL","lipoprotein lipase","Cytoplasm","enzyme",0.0019518846,0.00095576775,"down",1.3136675,-1.3136675,-0.3936002]
["PPARα/RXRα Activation",0.953,0.0562,-0.378,"PRKAA2","protein kinase AMP-activated catalytic subunit alpha 2","Cytoplasm","kinase",0.0014867174,0.0005054725,"up",1.3466656,1.3466656,0.42939165]
["PPARα/RXRα Activation",0.953,0.0562,-0.378,"PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["PPARα/RXRα Activation",0.953,0.0562,-0.378,"HSP90AA1","heat shock protein 90kDa alpha family class A member 1","Cytoplasm","enzyme",0.0005783946,2.0937947e-05,"up",1.5556576,1.5556576,0.63752455]
["PPARα/RXRα Activation",0.953,0.0562,-0.378,"ADIPOR2","adiponectin receptor 2","Plasma Membrane","other",0.00089824985,0.00011682664,"up",1.4429079,1.4429079,0.52897924]
["Mismatch Repair in Eukaryotes",0.951,0.125,"NaN","PCNA","proliferating cell nuclear antigen","Nucleus","enzyme",0.0032386743,0.0020517183,"down",1.3257968,-1.3257968,-0.40685973]
["Mismatch Repair in Eukaryotes",0.951,0.125,"NaN","RFC1","replication factor C subunit 1","Nucleus","transcription regulator",0.011040431,0.009618774,"up",1.3221459,1.3221459,0.4028814]
["Role of JAK1 and JAK3 in γc Cytokine Signaling",0.946,0.0704,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Role of JAK1 and JAK3 in γc Cytokine Signaling",0.946,0.0704,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Role of JAK1 and JAK3 in γc Cytokine Signaling",0.946,0.0704,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Role of JAK1 and JAK3 in γc Cytokine Signaling",0.946,0.0704,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Role of JAK1 and JAK3 in γc Cytokine Signaling",0.946,0.0704,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Protein Kinase A Signaling",0.937,0.0487,1.291,"AKAP12","A-kinase anchoring protein 12","Cytoplasm","transporter",0.0007292708,6.375623e-05,"up",2.0517201,2.0517201,1.036834]
["Protein Kinase A Signaling",0.937,0.0487,1.291,"GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["Protein Kinase A Signaling",0.937,0.0487,1.291,"TGFBR1","transforming growth factor beta receptor 1","Plasma Membrane","kinase",0.0008942897,0.00011058827,"up",1.5758384,1.5758384,0.65611964]
["Protein Kinase A Signaling",0.937,0.0487,1.291,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Protein Kinase A Signaling",0.937,0.0487,1.291,"ATF1","activating transcription factor 1","Nucleus","transcription regulator",0.0070709703,0.005685401,"down",1.3784643,-1.3784643,-0.46306193]
["Protein Kinase A Signaling",0.937,0.0487,1.291,"MYL6B","myosin light chain 6B","Cytoplasm","other",0.0037700427,0.0025393397,"up",1.3426967,1.3426967,0.4251334]
["Protein Kinase A Signaling",0.937,0.0487,1.291,"CDC23","cell division cycle 23","Nucleus","enzyme",0.001459056,0.0004736629,"down",1.4613066,-1.4613066,-0.54725885]
["Protein Kinase A Signaling",0.937,0.0487,1.291,"ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["Protein Kinase A Signaling",0.937,0.0487,1.291,"PTP4A1","protein tyrosine phosphatase type IVA, member 1","Cytoplasm","phosphatase",0.0022963006,0.0012550516,"down",1.9534479,-1.9534479,-0.9660228]
["Protein Kinase A Signaling",0.937,0.0487,1.291,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["Protein Kinase A Signaling",0.937,0.0487,1.291,"PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["Protein Kinase A Signaling",0.937,0.0487,1.291,"ROCK2","Rho associated coiled-coil containing protein kinase 2","Cytoplasm","kinase",0.0010184328,0.00016622998,"up",1.3479002,1.3479002,0.43071362]
["Protein Kinase A Signaling",0.937,0.0487,1.291,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Protein Kinase A Signaling",0.937,0.0487,1.291,"HHAT","hedgehog acyltransferase","Cytoplasm","enzyme",0.001277893,0.00032523135,"up",2.8401747,2.8401747,1.5059797]
["Protein Kinase A Signaling",0.937,0.0487,1.291,"PDE3B","phosphodiesterase 3B","Cytoplasm","enzyme",0.0026252405,0.0015308249,"up",1.3255126,1.3255126,0.40655044]
["Protein Kinase A Signaling",0.937,0.0487,1.291,"KDELR3","KDEL endoplasmic reticulum protein retention receptor 3","Cytoplasm","transporter",0.00070557836,5.5786673e-05,"up",1.4403156,1.4403156,0.52638495]
["Protein Kinase A Signaling",0.937,0.0487,1.291,"PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Protein Kinase A Signaling",0.937,0.0487,1.291,"PTGS2","prostaglandin-endoperoxide synthase 2","Cytoplasm","enzyme",0.0012584343,0.00031259237,"down",1.4767396,-1.4767396,-0.5624155]
["Protein Kinase A Signaling",0.937,0.0487,1.291,"CDC27","cell division cycle 27","Nucleus","other",0.0016711045,0.00067578256,"up",1.3830807,1.3830807,0.46788535]
["Systemic Lupus Erythematosus Signaling",0.936,0.0533,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Systemic Lupus Erythematosus Signaling",0.936,0.0533,"NaN","LSM14A","LSM14A mRNA processing body assembly factor","Cytoplasm","other",0.0010362655,0.0001717347,"down",2.4510098,-2.4510098,-1.2933762]
["Systemic Lupus Erythematosus Signaling",0.936,0.0533,"NaN","LSM14B","LSM family member 14B","Other","other",0.0020028213,0.0010039983,"down",1.5215487,-1.5215487,-0.6055406]
["Systemic Lupus Erythematosus Signaling",0.936,0.0533,"NaN","LSM8","LSM8 homolog, U6 small nuclear RNA associated","Nucleus","other",0.0021199163,0.0010983213,"up",1.4512854,1.4512854,0.5373312]
["Systemic Lupus Erythematosus Signaling",0.936,0.0533,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Systemic Lupus Erythematosus Signaling",0.936,0.0533,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Systemic Lupus Erythematosus Signaling",0.936,0.0533,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Systemic Lupus Erythematosus Signaling",0.936,0.0533,"NaN","PRPF4B","pre-mRNA processing factor 4B","Nucleus","kinase",0.012723735,0.0113428645,"down",1.3757049,-1.3757049,-0.460171]
["Systemic Lupus Erythematosus Signaling",0.936,0.0533,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Systemic Lupus Erythematosus Signaling",0.936,0.0533,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Systemic Lupus Erythematosus Signaling",0.936,0.0533,"NaN","HLA-F","major histocompatibility complex, class I, F","Plasma Membrane","transmembrane receptor",0.00070557836,5.4619704e-05,"up",1.622745,1.622745,0.6984363]
["Systemic Lupus Erythematosus Signaling",0.936,0.0533,"NaN","LSM5","LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated","Cytoplasm","other",0.00067191356,4.1958425e-05,"down",1.5488204,-1.5488204,-0.63116986]
["Basal Cell Carcinoma Signaling",0.927,0.0694,-1.342,"FZD10","frizzled class receptor 10","Plasma Membrane","G-protein coupled receptor",0.00084399927,9.184798e-05,"down",1.4670624,-1.4670624,-0.5529302]
["Basal Cell Carcinoma Signaling",0.927,0.0694,-1.342,"GLI2","GLI family zinc finger 2","Nucleus","transcription regulator",0.0009526495,0.00013251757,"down",1.5357528,-1.5357528,-0.61894596]
["Basal Cell Carcinoma Signaling",0.927,0.0694,-1.342,"FZD5","frizzled class receptor 5","Plasma Membrane","G-protein coupled receptor",0.0011555209,0.00024123449,"down",1.5153433,-1.5153433,-0.59964466]
["Basal Cell Carcinoma Signaling",0.927,0.0694,-1.342,"FZD1","frizzled class receptor 1","Plasma Membrane","G-protein coupled receptor",0.0036817046,0.002460812,"down",1.529664,-1.529664,-0.6132148]
["Basal Cell Carcinoma Signaling",0.927,0.0694,-1.342,"BMP6","bone morphogenetic protein 6","Extracellular Space","growth factor",0.0012361597,0.00030026503,"up",1.359715,1.359715,0.44330427]
["Ceramide Signaling",0.921,0.0645,-0.447,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Ceramide Signaling",0.921,0.0645,-0.447,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Ceramide Signaling",0.921,0.0645,-0.447,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Ceramide Signaling",0.921,0.0645,-0.447,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Ceramide Signaling",0.921,0.0645,-0.447,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Ceramide Signaling",0.921,0.0645,-0.447,"NSMAF","neutral sphingomyelinase activation associated factor","Cytoplasm","other",0.0006942706,4.3952532e-05,"down",3.3836162,-3.3836162,-1.7585659]
["TWEAK Signaling",0.91,0.0882,"NaN","TRADD","TNFRSF1A associated via death domain","Cytoplasm","other",0.0016301863,0.0006398275,"up",1.3732907,1.3732907,0.457637]
["TWEAK Signaling",0.91,0.0882,"NaN","IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["TWEAK Signaling",0.91,0.0882,"NaN","TNFRSF12A","tumor necrosis factor receptor superfamily member 12A","Plasma Membrane","transmembrane receptor",0.0014867174,0.00050635205,"up",1.3754094,1.3754094,0.45986107]
["Ephrin B Signaling",0.908,0.0685,"NaN","ROCK2","Rho associated coiled-coil containing protein kinase 2","Cytoplasm","kinase",0.0010184328,0.00016622998,"up",1.3479002,1.3479002,0.43071362]
["Ephrin B Signaling",0.908,0.0685,"NaN","GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["Ephrin B Signaling",0.908,0.0685,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Ephrin B Signaling",0.908,0.0685,"NaN","CXCR4","C-X-C motif chemokine receptor 4","Plasma Membrane","G-protein coupled receptor",0.0018305046,0.00083504117,"down",1.3248457,-1.3248457,-0.4058243]
["Ephrin B Signaling",0.908,0.0685,"NaN","CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["Actin Cytoskeleton Signaling",0.906,0.0526,0.577,"ROCK2","Rho associated coiled-coil containing protein kinase 2","Cytoplasm","kinase",0.0010184328,0.00016622998,"up",1.3479002,1.3479002,0.43071362]
["Actin Cytoskeleton Signaling",0.906,0.0526,0.577,"ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["Actin Cytoskeleton Signaling",0.906,0.0526,0.577,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Actin Cytoskeleton Signaling",0.906,0.0526,0.577,"ABI2","abl-interactor 2","Cytoplasm","other",0.001550606,0.0005515692,"up",1.458196,1.458196,0.5441847]
["Actin Cytoskeleton Signaling",0.906,0.0526,0.577,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Actin Cytoskeleton Signaling",0.906,0.0526,0.577,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Actin Cytoskeleton Signaling",0.906,0.0526,0.577,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["Actin Cytoskeleton Signaling",0.906,0.0526,0.577,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Actin Cytoskeleton Signaling",0.906,0.0526,0.577,"WASL","Wiskott-Aldrich syndrome like","Cytoplasm","other",0.00040977335,6.54692e-06,"up",1.4019742,1.4019742,0.4874598]
["Actin Cytoskeleton Signaling",0.906,0.0526,0.577,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Actin Cytoskeleton Signaling",0.906,0.0526,0.577,"LIMK2","LIM domain kinase 2","Cytoplasm","kinase",0.0035328772,0.002318736,"up",1.3875531,1.3875531,0.47254297]
["Actin Cytoskeleton Signaling",0.906,0.0526,0.577,"MYL6B","myosin light chain 6B","Cytoplasm","other",0.0037700427,0.0025393397,"up",1.3426967,1.3426967,0.4251334]
["IL-17A Signaling in Fibroblasts",0.882,0.0857,"NaN","IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["IL-17A Signaling in Fibroblasts",0.882,0.0857,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["IL-17A Signaling in Fibroblasts",0.882,0.0857,"NaN","CEBPB","CCAAT/enhancer binding protein beta","Nucleus","transcription regulator",0.021593252,0.020254135,"down",1.3026826,-1.3026826,-0.38148564]
["2-ketoglutarate Dehydrogenase Complex",0.864,0.25,"NaN","DHTKD1","dehydrogenase E1 and transketolase domain containing 1","Cytoplasm","enzyme",0.0012233602,0.0002803407,"up",1.3357142,1.3357142,0.41761136]
["Myo-inositol Biosynthesis",0.864,0.25,"NaN","IMPA2","inositol monophosphatase 2","Cytoplasm","phosphatase",0.00084399927,9.163144e-05,"down",1.303337,-1.303337,-0.38221014]
["Geranylgeranyldiphosphate Biosynthesis",0.864,0.25,"NaN","GGPS1","geranylgeranyl diphosphate synthase 1","Cytoplasm","enzyme",0.0020834338,0.0010650456,"up",1.3196927,1.3196927,0.40020207]
["CTLA4 Signaling in Cytotoxic T Lymphocytes",0.829,0.0606,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["CTLA4 Signaling in Cytotoxic T Lymphocytes",0.829,0.0606,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["CTLA4 Signaling in Cytotoxic T Lymphocytes",0.829,0.0606,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["CTLA4 Signaling in Cytotoxic T Lymphocytes",0.829,0.0606,"NaN","AP1S2","adaptor related protein complex 1 sigma 2 subunit","Cytoplasm","transporter",0.0011555209,0.00024228012,"up",1.5709138,1.5709138,0.651604]
["CTLA4 Signaling in Cytotoxic T Lymphocytes",0.829,0.0606,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["CTLA4 Signaling in Cytotoxic T Lymphocytes",0.829,0.0606,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Wnt/Ca+ pathway",0.824,0.0702,-1,"FZD10","frizzled class receptor 10","Plasma Membrane","G-protein coupled receptor",0.00084399927,9.184798e-05,"down",1.4670624,-1.4670624,-0.5529302]
["Wnt/Ca+ pathway",0.824,0.0702,-1,"FZD5","frizzled class receptor 5","Plasma Membrane","G-protein coupled receptor",0.0011555209,0.00024123449,"down",1.5153433,-1.5153433,-0.59964466]
["Wnt/Ca+ pathway",0.824,0.0702,-1,"FZD1","frizzled class receptor 1","Plasma Membrane","G-protein coupled receptor",0.0036817046,0.002460812,"down",1.529664,-1.529664,-0.6132148]
["Wnt/Ca+ pathway",0.824,0.0702,-1,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["Dendritic Cell Maturation",0.822,0.0526,1.265,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Dendritic Cell Maturation",0.822,0.0526,1.265,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["Dendritic Cell Maturation",0.822,0.0526,1.265,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Dendritic Cell Maturation",0.822,0.0526,1.265,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Dendritic Cell Maturation",0.822,0.0526,1.265,"MYD88","myeloid differentiation primary response 88","Plasma Membrane","other",0.0019091989,0.0009046913,"down",1.3930262,-1.3930262,-0.47822243]
["Dendritic Cell Maturation",0.822,0.0526,1.265,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Dendritic Cell Maturation",0.822,0.0526,1.265,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Dendritic Cell Maturation",0.822,0.0526,1.265,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Dendritic Cell Maturation",0.822,0.0526,1.265,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Dendritic Cell Maturation",0.822,0.0526,1.265,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["VDR/RXR Activation",0.821,0.0641,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["VDR/RXR Activation",0.821,0.0641,"NaN","MED1","mediator complex subunit 1","Nucleus","transcription regulator",0.007830824,0.006407651,"down",1.3726159,-1.3726159,-0.456928]
["VDR/RXR Activation",0.821,0.0641,"NaN","CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["VDR/RXR Activation",0.821,0.0641,"NaN","CEBPB","CCAAT/enhancer binding protein beta","Nucleus","transcription regulator",0.021593252,0.020254135,"down",1.3026826,-1.3026826,-0.38148564]
["VDR/RXR Activation",0.821,0.0641,"NaN","IGFBP1","insulin like growth factor binding protein 1","Extracellular Space","other",0.0010769006,0.00018458503,"down",1.3619553,-1.3619553,-0.44567934]
["Cyclins and Cell Cycle Regulation",0.821,0.0641,"NaN","HDAC6","histone deacetylase 6","Nucleus","transcription regulator",0.0060592825,0.0047327504,"up",1.6543902,1.6543902,0.7262995]
["Cyclins and Cell Cycle Regulation",0.821,0.0641,"NaN","CCNE1","cyclin E1","Nucleus","transcription regulator",0.0013342145,0.00036659295,"down",2.6488216,-2.6488216,-1.4053507]
["Cyclins and Cell Cycle Regulation",0.821,0.0641,"NaN","CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["Cyclins and Cell Cycle Regulation",0.821,0.0641,"NaN","CDK6","cyclin-dependent kinase 6","Nucleus","kinase",0.0011555209,0.0002428485,"down",1.6726129,-1.6726129,-0.7421036]
["Cyclins and Cell Cycle Regulation",0.821,0.0641,"NaN","SKP2","S-phase kinase-associated protein 2, E3 ubiquitin protein ligase","Nucleus","enzyme",0.0014867174,0.000499228,"up",1.348095,1.348095,0.4309222]
["Natural Killer Cell Signaling",0.816,0.0574,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Natural Killer Cell Signaling",0.816,0.0574,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Natural Killer Cell Signaling",0.816,0.0574,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Natural Killer Cell Signaling",0.816,0.0574,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Natural Killer Cell Signaling",0.816,0.0574,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Natural Killer Cell Signaling",0.816,0.0574,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Natural Killer Cell Signaling",0.816,0.0574,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["April Mediated Signaling",0.805,0.0789,"NaN","IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["April Mediated Signaling",0.805,0.0789,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["April Mediated Signaling",0.805,0.0789,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Wnt/β-catenin Signaling",0.799,0.0533,-1.633,"SOX2","SRY-box 2","Nucleus","transcription regulator",0.0013107243,0.00034832067,"up",1.4385506,1.4385506,0.52461594]
["Wnt/β-catenin Signaling",0.799,0.0533,-1.633,"FZD10","frizzled class receptor 10","Plasma Membrane","G-protein coupled receptor",0.00084399927,9.184798e-05,"down",1.4670624,-1.4670624,-0.5529302]
["Wnt/β-catenin Signaling",0.799,0.0533,-1.633,"APPL1","adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1","Cytoplasm","other",0.0016089604,0.0006085526,"up",1.4972963,1.4972963,0.5823598]
["Wnt/β-catenin Signaling",0.799,0.0533,-1.633,"CDH2","cadherin 2","Plasma Membrane","other",0.001091852,0.00020167766,"up",1.3591936,1.3591936,0.44275093]
["Wnt/β-catenin Signaling",0.799,0.0533,-1.633,"CDH1","cadherin 1","Plasma Membrane","other",0.0017019173,0.0006999703,"up",1.452055,1.452055,0.5380961]
["Wnt/β-catenin Signaling",0.799,0.0533,-1.633,"TGFBR1","transforming growth factor beta receptor 1","Plasma Membrane","kinase",0.0008942897,0.00011058827,"up",1.5758384,1.5758384,0.65611964]
["Wnt/β-catenin Signaling",0.799,0.0533,-1.633,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Wnt/β-catenin Signaling",0.799,0.0533,-1.633,"FZD5","frizzled class receptor 5","Plasma Membrane","G-protein coupled receptor",0.0011555209,0.00024123449,"down",1.5153433,-1.5153433,-0.59964466]
["Wnt/β-catenin Signaling",0.799,0.0533,-1.633,"FZD1","frizzled class receptor 1","Plasma Membrane","G-protein coupled receptor",0.0036817046,0.002460812,"down",1.529664,-1.529664,-0.6132148]
["Production of Nitric Oxide and Reactive Oxygen Species in Macrophages",0.792,0.0518,0.632,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Production of Nitric Oxide and Reactive Oxygen Species in Macrophages",0.792,0.0518,0.632,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["Production of Nitric Oxide and Reactive Oxygen Species in Macrophages",0.792,0.0518,0.632,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Production of Nitric Oxide and Reactive Oxygen Species in Macrophages",0.792,0.0518,0.632,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Production of Nitric Oxide and Reactive Oxygen Species in Macrophages",0.792,0.0518,0.632,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Production of Nitric Oxide and Reactive Oxygen Species in Macrophages",0.792,0.0518,0.632,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Production of Nitric Oxide and Reactive Oxygen Species in Macrophages",0.792,0.0518,0.632,"RHOU","ras homolog family member U","Cytoplasm","enzyme",0.0009194498,0.00012193339,"down",1.7715495,-1.7715495,-0.82501173]
["Production of Nitric Oxide and Reactive Oxygen Species in Macrophages",0.792,0.0518,0.632,"AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["Production of Nitric Oxide and Reactive Oxygen Species in Macrophages",0.792,0.0518,0.632,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Production of Nitric Oxide and Reactive Oxygen Species in Macrophages",0.792,0.0518,0.632,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["D-myo-inositol (1,3,4)-trisphosphate Biosynthesis",0.792,0.1,"NaN","INPP5A","inositol polyphosphate-5-phosphatase A","Plasma Membrane","phosphatase",0.0017193076,0.00071636395,"up",1.6724749,1.6724749,0.7419845]
["D-myo-inositol (1,3,4)-trisphosphate Biosynthesis",0.792,0.1,"NaN","PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["Tec Kinase Signaling",0.789,0.0529,-0.707,"ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["Tec Kinase Signaling",0.789,0.0529,-0.707,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["Tec Kinase Signaling",0.789,0.0529,-0.707,"GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["Tec Kinase Signaling",0.789,0.0529,-0.707,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Tec Kinase Signaling",0.789,0.0529,-0.707,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Tec Kinase Signaling",0.789,0.0529,-0.707,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Tec Kinase Signaling",0.789,0.0529,-0.707,"RHOU","ras homolog family member U","Cytoplasm","enzyme",0.0009194498,0.00012193339,"down",1.7715495,-1.7715495,-0.82501173]
["Tec Kinase Signaling",0.789,0.0529,-0.707,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Tec Kinase Signaling",0.789,0.0529,-0.707,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["MSP-RON Signaling Pathway",0.786,0.0678,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["MSP-RON Signaling Pathway",0.786,0.0678,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["MSP-RON Signaling Pathway",0.786,0.0678,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["MSP-RON Signaling Pathway",0.786,0.0678,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Inhibition of Matrix Metalloproteases",0.781,0.0769,"NaN","SDC1","syndecan 1","Plasma Membrane","enzyme",0.001123322,0.00022071275,"up",1.3963997,1.3963997,0.48171198]
["Inhibition of Matrix Metalloproteases",0.781,0.0769,"NaN","ADAM12","ADAM metallopeptidase domain 12","Plasma Membrane","peptidase",0.0039314847,0.0026751703,"down",1.4494704,-1.4494704,-0.53552586]
["Inhibition of Matrix Metalloproteases",0.781,0.0769,"NaN","SDC2","syndecan 2","Plasma Membrane","other",0.00067191356,4.108484e-05,"up",1.8298745,1.8298745,0.8717447]
["Creatine-phosphate Biosynthesis",0.775,0.2,"NaN","CKMT1A/CKMT1B","creatine kinase, mitochondrial 1B","Cytoplasm","kinase",0.0029613448,0.0018150214,"up",2.094609,2.094609,1.0666809]
["Lysine Degradation II",0.775,0.2,"NaN","AASDHPPT","aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase","Cytoplasm","enzyme",0.00171664,0.0007141577,"down",1.6685405,-1.6685405,-0.73858666]
["Lysine Degradation V",0.775,0.2,"NaN","AASDHPPT","aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase","Cytoplasm","enzyme",0.00171664,0.0007141577,"down",1.6685405,-1.6685405,-0.73858666]
["Trans, trans-farnesyl Diphosphate Biosynthesis",0.775,0.2,"NaN","GGPS1","geranylgeranyl diphosphate synthase 1","Cytoplasm","enzyme",0.0020834338,0.0010650456,"up",1.3196927,1.3196927,0.40020207]
["Tyrosine Degradation I",0.775,0.2,"NaN","HPD","4-hydroxyphenylpyruvate dioxygenase","Cytoplasm","enzyme",0.0029613448,0.0018153565,"up",1.5377063,1.5377063,0.62077993]
["Induction of Apoptosis by HIV1",0.768,0.0667,1,"TRADD","TNFRSF1A associated via death domain","Cytoplasm","other",0.0016301863,0.0006398275,"up",1.3732907,1.3732907,0.457637]
["Induction of Apoptosis by HIV1",0.768,0.0667,1,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["Induction of Apoptosis by HIV1",0.768,0.0667,1,"CXCR4","C-X-C motif chemokine receptor 4","Plasma Membrane","G-protein coupled receptor",0.0018305046,0.00083504117,"down",1.3248457,-1.3248457,-0.4058243]
["Induction of Apoptosis by HIV1",0.768,0.0667,1,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["B Cell Activating Factor Signaling",0.758,0.075,"NaN","IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["B Cell Activating Factor Signaling",0.758,0.075,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["B Cell Activating Factor Signaling",0.758,0.075,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["MIF Regulation of Innate Immunity",0.736,0.0732,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["MIF Regulation of Innate Immunity",0.736,0.0732,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["MIF Regulation of Innate Immunity",0.736,0.0732,"NaN","PTGS2","prostaglandin-endoperoxide synthase 2","Cytoplasm","enzyme",0.0012584343,0.00031259237,"down",1.4767396,-1.4767396,-0.5624155]
["Mechanisms of Viral Exit from Host Cells",0.736,0.0732,"NaN","NEDD4","neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase","Cytoplasm","enzyme",0.00067191356,4.1885378e-05,"up",2.6203134,2.6203134,1.3897394]
["Mechanisms of Viral Exit from Host Cells",0.736,0.0732,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Mechanisms of Viral Exit from Host Cells",0.736,0.0732,"NaN","CHMP2B","charged multivesicular body protein 2B","Cytoplasm","other",0.003205884,0.0020240422,"up",1.3364353,1.3364353,0.41839]
["ERK/MAPK Signaling",0.735,0.0503,0,"ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["ERK/MAPK Signaling",0.735,0.0503,0,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["ERK/MAPK Signaling",0.735,0.0503,0,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["ERK/MAPK Signaling",0.735,0.0503,0,"ATF1","activating transcription factor 1","Nucleus","transcription regulator",0.0070709703,0.005685401,"down",1.3784643,-1.3784643,-0.46306193]
["ERK/MAPK Signaling",0.735,0.0503,0,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["ERK/MAPK Signaling",0.735,0.0503,0,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["ERK/MAPK Signaling",0.735,0.0503,0,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["ERK/MAPK Signaling",0.735,0.0503,0,"PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["ERK/MAPK Signaling",0.735,0.0503,0,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["ERK/MAPK Signaling",0.735,0.0503,0,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["Activation of IRF by Cytosolic Pattern Recognition Receptors",0.733,0.0645,1,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["Activation of IRF by Cytosolic Pattern Recognition Receptors",0.733,0.0645,1,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Activation of IRF by Cytosolic Pattern Recognition Receptors",0.733,0.0645,1,"TBK1","TANK binding kinase 1","Cytoplasm","kinase",0.005976595,0.004633019,"down",1.3411525,-1.3411525,-0.42347333]
["Activation of IRF by Cytosolic Pattern Recognition Receptors",0.733,0.0645,1,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["ERK5 Signaling",0.716,0.0635,-1,"MEF2D","myocyte enhancer factor 2D","Nucleus","transcription regulator",0.0006217929,3.203251e-05,"down",1.3555743,-1.3555743,-0.43890414]
["ERK5 Signaling",0.716,0.0635,-1,"RPS6KB2","ribosomal protein S6 kinase B2","Cytoplasm","kinase",0.0016431456,0.0006520507,"down",1.986918,-1.986918,-0.9905323]
["ERK5 Signaling",0.716,0.0635,-1,"MEF2A","myocyte enhancer factor 2A","Nucleus","transcription regulator",0.015937602,0.014585446,"down",1.3274704,-1.3274704,-0.40867972]
["ERK5 Signaling",0.716,0.0635,-1,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["UVC-Induced MAPK Signaling",0.715,0.0714,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["UVC-Induced MAPK Signaling",0.715,0.0714,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["UVC-Induced MAPK Signaling",0.715,0.0714,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Ceramide Biosynthesis",0.703,0.167,"NaN","SPTLC2","serine palmitoyltransferase long chain base subunit 2","Cytoplasm","enzyme",0.0016763486,0.0006851227,"up",1.530053,1.530053,0.61358166]
["Pentose Phosphate Pathway (Non-oxidative Branch)",0.703,0.167,"NaN","TKT","transketolase","Cytoplasm","enzyme",0.00444491,0.0031397163,"down",1.6452134,-1.6452134,-0.7182747]
["UDP-N-acetyl-D-glucosamine Biosynthesis II",0.703,0.167,"NaN","GFPT1","glutamine--fructose-6-phosphate transaminase 1","Cytoplasm","enzyme",0.0007085977,5.762598e-05,"up",1.3279264,1.3279264,0.4091752]
["Ceramide Degradation",0.703,0.167,"NaN","ASAH1","N-acylsphingosine amidohydrolase (acid ceramidase) 1","Cytoplasm","enzyme",0.007317322,0.0059212954,"down",1.4117956,-1.4117956,-0.49753124]
["Zymosterol Biosynthesis",0.703,0.167,"NaN","MSMO1","methylsterol monooxygenase 1","Cytoplasm","enzyme",0.0012443048,0.00030560244,"up",1.4843444,1.4843444,0.5698258]
["Molybdenum Cofactor Biosynthesis",0.703,0.167,"NaN","GPHN","gephyrin","Plasma Membrane","enzyme",0.0065242443,0.0051553696,"up",1.3237419,1.3237419,0.40462187]
["GDP-mannose Biosynthesis",0.703,0.167,"NaN","MPI","mannose phosphate isomerase","Cytoplasm","enzyme",0.00091646257,0.00012077414,"up",1.4872181,1.4872181,0.5726163]
["Pyrimidine Deoxyribonucleotides De Novo Biosynthesis I",0.697,0.087,"NaN","RRM2","ribonucleotide reductase regulatory subunit M2","Nucleus","enzyme",0.0008942897,0.0001145765,"down",1.7864425,-1.7864425,-0.8370895]
["Pyrimidine Deoxyribonucleotides De Novo Biosynthesis I",0.697,0.087,"NaN","CMPK1","cytidine/uridine monophosphate kinase 1","Nucleus","kinase",0.00036445798,4.4485446e-06,"down",3.5441682,-3.5441682,-1.8254471]
["T Cell Receptor Signaling",0.696,0.055,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["T Cell Receptor Signaling",0.696,0.055,"NaN","IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["T Cell Receptor Signaling",0.696,0.055,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["T Cell Receptor Signaling",0.696,0.055,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["T Cell Receptor Signaling",0.696,0.055,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["T Cell Receptor Signaling",0.696,0.055,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["α-Adrenergic Signaling",0.687,0.0575,0,"GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["α-Adrenergic Signaling",0.687,0.0575,0,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["α-Adrenergic Signaling",0.687,0.0575,0,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["α-Adrenergic Signaling",0.687,0.0575,0,"PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["α-Adrenergic Signaling",0.687,0.0575,0,"ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["Type I Diabetes Mellitus Signaling",0.684,0.0545,1.342,"TRADD","TNFRSF1A associated via death domain","Cytoplasm","other",0.0016301863,0.0006398275,"up",1.3732907,1.3732907,0.457637]
["Type I Diabetes Mellitus Signaling",0.684,0.0545,1.342,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["Type I Diabetes Mellitus Signaling",0.684,0.0545,1.342,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Type I Diabetes Mellitus Signaling",0.684,0.0545,1.342,"MYD88","myeloid differentiation primary response 88","Plasma Membrane","other",0.0019091989,0.0009046913,"down",1.3930262,-1.3930262,-0.47822243]
["Type I Diabetes Mellitus Signaling",0.684,0.0545,1.342,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Type I Diabetes Mellitus Signaling",0.684,0.0545,1.342,"HLA-F","major histocompatibility complex, class I, F","Plasma Membrane","transmembrane receptor",0.00070557836,5.4619704e-05,"up",1.622745,1.622745,0.6984363]
["PXR/RXR Activation",0.683,0.0615,"NaN","PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["PXR/RXR Activation",0.683,0.0615,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["PXR/RXR Activation",0.683,0.0615,"NaN","IGFBP1","insulin like growth factor binding protein 1","Extracellular Space","other",0.0010769006,0.00018458503,"down",1.3619553,-1.3619553,-0.44567934]
["PXR/RXR Activation",0.683,0.0615,"NaN","HNF4A","hepatocyte nuclear factor 4 alpha","Nucleus","transcription regulator",0.0018693322,0.0008653767,"up",1.4698008,1.4698008,0.5556207]
["Role of IL-17F in Allergic Inflammatory Airway Diseases",0.675,0.0682,"NaN","CXCL8","C-X-C motif chemokine ligand 8","Extracellular Space","cytokine",0.0011259156,0.00022286079,"down",1.5851029,-1.5851029,-0.66457653]
["Role of IL-17F in Allergic Inflammatory Airway Diseases",0.675,0.0682,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Role of IL-17F in Allergic Inflammatory Airway Diseases",0.675,0.0682,"NaN","ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["iNOS Signaling",0.675,0.0682,"NaN","IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["iNOS Signaling",0.675,0.0682,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["iNOS Signaling",0.675,0.0682,"NaN","MYD88","myeloid differentiation primary response 88","Plasma Membrane","other",0.0019091989,0.0009046913,"down",1.3930262,-1.3930262,-0.47822243]
["Triacylglycerol Biosynthesis",0.675,0.0682,"NaN","MBOAT2","membrane bound O-acyltransferase domain containing 2","Cytoplasm","enzyme",0.001550606,0.00055170426,"up",1.5328599,1.5328599,0.61622584]
["Triacylglycerol Biosynthesis",0.675,0.0682,"NaN","PLPP2","phospholipid phosphatase 2","Plasma Membrane","phosphatase",0.0006216412,2.9067676e-05,"down",1.9396921,-1.9396921,-0.95582765]
["Triacylglycerol Biosynthesis",0.675,0.0682,"NaN","ELOVL6","ELOVL fatty acid elongase 6","Cytoplasm","enzyme",0.003911406,0.0026581388,"up",1.4015174,1.4015174,0.48698965]
["Androgen Signaling",0.672,0.0541,"NaN","GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["Androgen Signaling",0.672,0.0541,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Androgen Signaling",0.672,0.0541,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Androgen Signaling",0.672,0.0541,"NaN","PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Androgen Signaling",0.672,0.0541,"NaN","HSP90AA1","heat shock protein 90kDa alpha family class A member 1","Cytoplasm","enzyme",0.0005783946,2.0937947e-05,"up",1.5556576,1.5556576,0.63752455]
["Androgen Signaling",0.672,0.0541,"NaN","DNAJB1","DnaJ heat shock protein family (Hsp40) member B1","Nucleus","other",0.0012010665,0.0002643174,"down",2.432129,-2.432129,-1.2822196]
["Role of JAK family kinases in IL-6-type Cytokine Signaling",0.643,0.08,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Role of JAK family kinases in IL-6-type Cytokine Signaling",0.643,0.08,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Role of Oct4 in Mammalian Embryonic Stem Cell Pluripotency",0.637,0.0652,"NaN","SOX2","SRY-box 2","Nucleus","transcription regulator",0.0013107243,0.00034832067,"up",1.4385506,1.4385506,0.52461594]
["Role of Oct4 in Mammalian Embryonic Stem Cell Pluripotency",0.637,0.0652,"NaN","FAM208A","family with sequence similarity 208 member A","Other","other",0.0029773635,0.0018368062,"up",1.3251894,1.3251894,0.4061985]
["Role of Oct4 in Mammalian Embryonic Stem Cell Pluripotency",0.637,0.0652,"NaN","MEF2A","myocyte enhancer factor 2A","Nucleus","transcription regulator",0.015937602,0.014585446,"down",1.3274704,-1.3274704,-0.40867972]
["Regulation of Actin-based Motility by Rho",0.635,0.0549,-0.447,"ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["Regulation of Actin-based Motility by Rho",0.635,0.0549,-0.447,"CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["Regulation of Actin-based Motility by Rho",0.635,0.0549,-0.447,"WASL","Wiskott-Aldrich syndrome like","Cytoplasm","other",0.00040977335,6.54692e-06,"up",1.4019742,1.4019742,0.4874598]
["Regulation of Actin-based Motility by Rho",0.635,0.0549,-0.447,"RHOU","ras homolog family member U","Cytoplasm","enzyme",0.0009194498,0.00012193339,"down",1.7715495,-1.7715495,-0.82501173]
["Regulation of Actin-based Motility by Rho",0.635,0.0549,-0.447,"MYL6B","myosin light chain 6B","Cytoplasm","other",0.0037700427,0.0025393397,"up",1.3426967,1.3426967,0.4251334]
["CCR5 Signaling in Macrophages",0.623,0.058,"NaN","GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["CCR5 Signaling in Macrophages",0.623,0.058,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["CCR5 Signaling in Macrophages",0.623,0.058,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["CCR5 Signaling in Macrophages",0.623,0.058,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Agrin Interactions at Neuromuscular Junction",0.623,0.058,"NaN","ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["Agrin Interactions at Neuromuscular Junction",0.623,0.058,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Agrin Interactions at Neuromuscular Junction",0.623,0.058,"NaN","CDC42","cell division cycle 42","Cytoplasm","enzyme",0.0012237608,0.0002914469,"down",1.5838875,-1.5838875,-0.6634698]
["Agrin Interactions at Neuromuscular Junction",0.623,0.058,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Death Receptor Signaling",0.622,0.0543,-0.447,"TRADD","TNFRSF1A associated via death domain","Cytoplasm","other",0.0016301863,0.0006398275,"up",1.3732907,1.3732907,0.457637]
["Death Receptor Signaling",0.622,0.0543,-0.447,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["Death Receptor Signaling",0.622,0.0543,-0.447,"TIPARP","TCDD inducible poly(ADP-ribose) polymerase","Nucleus","enzyme",0.0011442282,0.00023684064,"down",1.3731275,-1.3731275,-0.45746553]
["Death Receptor Signaling",0.622,0.0543,-0.447,"CASP2","caspase 2","Cytoplasm","peptidase",0.0015242294,0.0005334935,"down",1.3856739,-1.3856739,-0.47058776]
["Death Receptor Signaling",0.622,0.0543,-0.447,"TBK1","TANK binding kinase 1","Cytoplasm","kinase",0.005976595,0.004633019,"down",1.3411525,-1.3411525,-0.42347333]
["Chemokine Signaling",0.595,0.0563,1,"ROCK2","Rho associated coiled-coil containing protein kinase 2","Cytoplasm","kinase",0.0010184328,0.00016622998,"up",1.3479002,1.3479002,0.43071362]
["Chemokine Signaling",0.595,0.0563,1,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Chemokine Signaling",0.595,0.0563,1,"CXCR4","C-X-C motif chemokine receptor 4","Plasma Membrane","G-protein coupled receptor",0.0018305046,0.00083504117,"down",1.3248457,-1.3248457,-0.4058243]
["Chemokine Signaling",0.595,0.0563,1,"LIMK2","LIM domain kinase 2","Cytoplasm","kinase",0.0035328772,0.002318736,"up",1.3875531,1.3875531,0.47254297]
["IL-15 Production",0.594,0.0741,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["IL-15 Production",0.594,0.0741,"NaN","TWF1","twinfilin actin binding protein 1","Cytoplasm","kinase",0.00047635857,9.0801705e-06,"up",1.3966414,1.3966414,0.4819616]
["Airway Pathology in Chronic Obstructive Pulmonary Disease",0.594,0.125,"NaN","CXCL8","C-X-C motif chemokine ligand 8","Extracellular Space","cytokine",0.0011259156,0.00022286079,"down",1.5851029,-1.5851029,-0.66457653]
["Sphingosine and Sphingosine-1-phosphate Metabolism",0.594,0.125,"NaN","ASAH1","N-acylsphingosine amidohydrolase (acid ceramidase) 1","Cytoplasm","enzyme",0.007317322,0.0059212954,"down",1.4117956,-1.4117956,-0.49753124]
["Histidine Degradation III",0.594,0.125,"NaN","HAL","histidine ammonia-lyase","Cytoplasm","enzyme",0.0060407864,0.004711397,"down",1.3929694,-1.3929694,-0.47816354]
["Citrulline Biosynthesis",0.594,0.125,"NaN","GLS","glutaminase","Cytoplasm","enzyme",0.0045107757,0.0032061748,"up",1.6075542,1.6075542,0.6848674]
["Purine Ribonucleosides Degradation to Ribose-1-phosphate",0.594,0.125,"NaN","PGM2","phosphoglucomutase 2","Cytoplasm","enzyme",0.0019427151,0.0009402669,"down",1.6117538,-1.6117538,-0.6886314]
["Glycoaminoglycan-protein Linkage Region Biosynthesis",0.594,0.125,"NaN","GXYLT1","glucoside xylosyltransferase 1","Cytoplasm","enzyme",0.0016147236,0.00061580446,"up",1.7539235,1.7539235,0.81058586]
["Sphingomyelin Metabolism",0.594,0.125,"NaN","SGMS1","sphingomyelin synthase 1","Cytoplasm","enzyme",0.001365887,0.00038529543,"up",1.6822836,1.6822836,0.750421]
["Gαi Signaling",0.575,0.05,"NaN","GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["Gαi Signaling",0.575,0.05,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Gαi Signaling",0.575,0.05,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Gαi Signaling",0.575,0.05,"NaN","RALB","v-ral simian leukemia viral oncogene homolog B","Cytoplasm","enzyme",0.0022762846,0.0012371538,"up",1.7571107,1.7571107,0.81320506]
["Gαi Signaling",0.575,0.05,"NaN","CAV1","caveolin 1","Plasma Membrane","transmembrane receptor",0.0014512807,0.00046188477,"up",1.5792397,1.5792397,0.6592302]
["Gαi Signaling",0.575,0.05,"NaN","PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["phagosome maturation",0.575,0.05,"NaN","TUBB3","tubulin beta 3 class III","Cytoplasm","other",0.001459056,0.00047059942,"up",1.4351482,1.4351482,0.52119976]
["phagosome maturation",0.575,0.05,"NaN","RAB5A","RAB5A, member RAS oncogene family","Cytoplasm","enzyme",0.001415604,0.00043224083,"up",1.4926699,1.4926699,0.57789516]
["phagosome maturation",0.575,0.05,"NaN","PRDX1","peroxiredoxin 1","Cytoplasm","enzyme",6.045441e-05,1.0414197e-07,"down",5.09895,-5.09895,-2.3502002]
["phagosome maturation",0.575,0.05,"NaN","TUBB2A","tubulin beta 2A class IIa","Cytoplasm","other",0.0026605518,0.0015617278,"up",1.4475315,1.4475315,0.5335947]
["phagosome maturation",0.575,0.05,"NaN","SNAP25","synaptosome associated protein 25kDa","Plasma Membrane","transporter",0.001213793,0.00027191787,"up",2.3686213,2.3686213,1.2440475]
["phagosome maturation",0.575,0.05,"NaN","ATP6V1B2","ATPase H+ transporting V1 subunit B2","Cytoplasm","transporter",0.0015485154,0.0005475156,"up",1.3054587,1.3054587,0.38455677]
["TNFR2 Signaling",0.55,0.069,"NaN","IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["TNFR2 Signaling",0.55,0.069,"NaN","TBK1","TANK binding kinase 1","Cytoplasm","kinase",0.005976595,0.004633019,"down",1.3411525,-1.3411525,-0.42347333]
["Prostanoid Biosynthesis",0.55,0.111,"NaN","PTGS2","prostaglandin-endoperoxide synthase 2","Cytoplasm","enzyme",0.0012584343,0.00031259237,"down",1.4767396,-1.4767396,-0.5624155]
["Phosphatidylethanolamine Biosynthesis II",0.55,0.111,"NaN","ETNK1","ethanolamine kinase 1","Cytoplasm","kinase",0.0007292708,6.348577e-05,"down",2.041355,-2.041355,-1.029527]
["GDP-glucose Biosynthesis",0.55,0.111,"NaN","PGM2","phosphoglucomutase 2","Cytoplasm","enzyme",0.0019427151,0.0009402669,"down",1.6117538,-1.6117538,-0.6886314]
["Heparan Sulfate Biosynthesis",0.543,0.0533,"NaN","CHST2","carbohydrate sulfotransferase 2","Cytoplasm","enzyme",0.0010089864,0.0001642536,"down",1.9582679,-1.9582679,-0.96957815]
["Heparan Sulfate Biosynthesis",0.543,0.0533,"NaN","CHST7","carbohydrate sulfotransferase 7","Cytoplasm","enzyme",0.001091852,0.00020487046,"up",1.4233469,1.4233469,0.5092873]
["Heparan Sulfate Biosynthesis",0.543,0.0533,"NaN","GXYLT1","glucoside xylosyltransferase 1","Cytoplasm","enzyme",0.0016147236,0.00061580446,"up",1.7539235,1.7539235,0.81058586]
["Heparan Sulfate Biosynthesis",0.543,0.0533,"NaN","GLCE","glucuronic acid epimerase","Cytoplasm","enzyme",0.0039742477,0.002717961,"down",1.3718114,-1.3718114,-0.45608214]
["Sonic Hedgehog Signaling",0.53,0.0667,"NaN","GLI2","GLI family zinc finger 2","Nucleus","transcription regulator",0.0009526495,0.00013251757,"down",1.5357528,-1.5357528,-0.61894596]
["Sonic Hedgehog Signaling",0.53,0.0667,"NaN","PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Sperm Motility",0.527,0.048,1.342,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Sperm Motility",0.527,0.048,1.342,"TWF1","twinfilin actin binding protein 1","Cytoplasm","kinase",0.00047635857,9.0801705e-06,"up",1.3966414,1.3966414,0.4819616]
["Sperm Motility",0.527,0.048,1.342,"SLC12A2","solute carrier family 12 member 2","Plasma Membrane","transporter",0.0040863724,0.0028245598,"up",1.3745189,1.3745189,0.4589267]
["Sperm Motility",0.527,0.048,1.342,"PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Sperm Motility",0.527,0.048,1.342,"ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["Sperm Motility",0.527,0.048,1.342,"PAFAH1B3","platelet activating factor acetylhydrolase 1b catalytic subunit 3","Cytoplasm","enzyme",0.0029175605,0.0017729017,"up",1.3077043,1.3077043,0.38703638]
["Glucose and Glucose-1-phosphate Degradation",0.512,0.1,"NaN","PGM2","phosphoglucomutase 2","Cytoplasm","enzyme",0.0019427151,0.0009402669,"down",1.6117538,-1.6117538,-0.6886314]
["Calcium Transport I",0.512,0.1,"NaN","ATP2C1","ATPase secretory pathway Ca2+ transporting 1","Cytoplasm","transporter",0.0045107757,0.0032051865,"up",1.313763,1.313763,0.39370507]
["Pentose Phosphate Pathway",0.512,0.1,"NaN","TKT","transketolase","Cytoplasm","enzyme",0.00444491,0.0031397163,"down",1.6452134,-1.6452134,-0.7182747]
["Histidine Degradation VI",0.512,0.1,"NaN","HAL","histidine ammonia-lyase","Cytoplasm","enzyme",0.0060407864,0.004711397,"down",1.3929694,-1.3929694,-0.47816354]
["Antioxidant Action of Vitamin C",0.502,0.0485,-2,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["Antioxidant Action of Vitamin C",0.502,0.0485,-2,"SLC2A1","solute carrier family 2 member 1","Plasma Membrane","transporter",0.0010998568,0.00021028184,"down",1.3829497,-1.3829497,-0.4677487]
["Antioxidant Action of Vitamin C",0.502,0.0485,-2,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Antioxidant Action of Vitamin C",0.502,0.0485,-2,"MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Antioxidant Action of Vitamin C",0.502,0.0485,-2,"PAFAH1B3","platelet activating factor acetylhydrolase 1b catalytic subunit 3","Cytoplasm","enzyme",0.0029175605,0.0017729017,"up",1.3077043,1.3077043,0.38703638]
["Estrogen Receptor Signaling",0.5,0.0469,"NaN","TAF1","TATA-box binding protein associated factor 1","Nucleus","transcription regulator",0.00084399927,9.268726e-05,"down",1.4030962,-1.4030962,-0.48861393]
["Estrogen Receptor Signaling",0.5,0.0469,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Estrogen Receptor Signaling",0.5,0.0469,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Estrogen Receptor Signaling",0.5,0.0469,"NaN","MED1","mediator complex subunit 1","Nucleus","transcription regulator",0.007830824,0.006407651,"down",1.3726159,-1.3726159,-0.456928]
["Estrogen Receptor Signaling",0.5,0.0469,"NaN","HNRNPD","heterogeneous nuclear ribonucleoprotein D","Nucleus","transcription regulator",0.0019427151,0.0009391086,"down",1.376271,-1.376271,-0.4607646]
["Estrogen Receptor Signaling",0.5,0.0469,"NaN","IGFBP1","insulin like growth factor binding protein 1","Extracellular Space","other",0.0010769006,0.00018458503,"down",1.3619553,-1.3619553,-0.44567934]
["Pyrimidine Ribonucleotides Interconversion",0.492,0.0625,"NaN","CMPK1","cytidine/uridine monophosphate kinase 1","Nucleus","kinase",0.00036445798,4.4485446e-06,"down",3.5441682,-3.5441682,-1.8254471]
["Pyrimidine Ribonucleotides Interconversion",0.492,0.0625,"NaN","ENTPD7","ectonucleoside triphosphate diphosphohydrolase 7","Cytoplasm","enzyme",0.0027023053,0.001596711,"up",1.4324039,1.4324039,0.51843834]
["PKCθ Signaling in T Lymphocytes",0.483,0.0462,0.816,"PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["PKCθ Signaling in T Lymphocytes",0.483,0.0462,0.816,"IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["PKCθ Signaling in T Lymphocytes",0.483,0.0462,0.816,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["PKCθ Signaling in T Lymphocytes",0.483,0.0462,0.816,"GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["PKCθ Signaling in T Lymphocytes",0.483,0.0462,0.816,"FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["PKCθ Signaling in T Lymphocytes",0.483,0.0462,0.816,"FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Glycogen Degradation II",0.478,0.0909,"NaN","PGM2","phosphoglucomutase 2","Cytoplasm","enzyme",0.0019427151,0.0009402669,"down",1.6117538,-1.6117538,-0.6886314]
["Dolichyl-diphosphooligosaccharide Biosynthesis",0.478,0.0909,"NaN","ALG5","ALG5, dolichyl-phosphate beta-glucosyltransferase","Cytoplasm","enzyme",0.001213793,0.00027234544,"up",2.029067,2.029067,1.0208166]
["Circadian Rhythm Signaling",0.474,0.0606,"NaN","BHLHE41","basic helix-loop-helix family member e41","Nucleus","transcription regulator",0.0061956346,0.004866855,"up",1.4149412,1.4149412,0.5007421]
["Circadian Rhythm Signaling",0.474,0.0606,"NaN","ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["MIF-mediated Glucocorticoid Regulation",0.474,0.0606,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["MIF-mediated Glucocorticoid Regulation",0.474,0.0606,"NaN","PTGS2","prostaglandin-endoperoxide synthase 2","Cytoplasm","enzyme",0.0012584343,0.00031259237,"down",1.4767396,-1.4767396,-0.5624155]
["Hepatic Fibrosis / Hepatic Stellate Cell Activation",0.467,0.0437,"NaN","MET","MET proto-oncogene, receptor tyrosine kinase","Plasma Membrane","kinase",0.0008691947,0.00010051858,"up",1.5833938,1.5833938,0.66302013]
["Hepatic Fibrosis / Hepatic Stellate Cell Activation",0.467,0.0437,"NaN","CXCL8","C-X-C motif chemokine ligand 8","Extracellular Space","cytokine",0.0011259156,0.00022286079,"down",1.5851029,-1.5851029,-0.66457653]
["Hepatic Fibrosis / Hepatic Stellate Cell Activation",0.467,0.0437,"NaN","TGFBR1","transforming growth factor beta receptor 1","Plasma Membrane","kinase",0.0008942897,0.00011058827,"up",1.5758384,1.5758384,0.65611964]
["Hepatic Fibrosis / Hepatic Stellate Cell Activation",0.467,0.0437,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["Hepatic Fibrosis / Hepatic Stellate Cell Activation",0.467,0.0437,"NaN","IGF1R","insulin like growth factor 1 receptor","Plasma Membrane","transmembrane receptor",0.0016147236,0.0006161828,"up",1.8701973,1.8701973,0.90319043]
["Hepatic Fibrosis / Hepatic Stellate Cell Activation",0.467,0.0437,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["Hepatic Fibrosis / Hepatic Stellate Cell Activation",0.467,0.0437,"NaN","MYL6B","myosin light chain 6B","Cytoplasm","other",0.0037700427,0.0025393397,"up",1.3426967,1.3426967,0.4251334]
["Hepatic Fibrosis / Hepatic Stellate Cell Activation",0.467,0.0437,"NaN","SERPINE1","serpin family E member 1","Extracellular Space","other",0.0016010772,0.00060374127,"up",1.3806411,1.3806411,0.46533832]
["Oncostatin M Signaling",0.457,0.0588,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Oncostatin M Signaling",0.457,0.0588,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["Pyrimidine Ribonucleotides De Novo Biosynthesis",0.457,0.0588,"NaN","CMPK1","cytidine/uridine monophosphate kinase 1","Nucleus","kinase",0.00036445798,4.4485446e-06,"down",3.5441682,-3.5441682,-1.8254471]
["Pyrimidine Ribonucleotides De Novo Biosynthesis",0.457,0.0588,"NaN","ENTPD7","ectonucleoside triphosphate diphosphohydrolase 7","Cytoplasm","enzyme",0.0027023053,0.001596711,"up",1.4324039,1.4324039,0.51843834]
["Chondroitin Sulfate Biosynthesis",0.457,0.0517,"NaN","CHST2","carbohydrate sulfotransferase 2","Cytoplasm","enzyme",0.0010089864,0.0001642536,"down",1.9582679,-1.9582679,-0.96957815]
["Chondroitin Sulfate Biosynthesis",0.457,0.0517,"NaN","CHST7","carbohydrate sulfotransferase 7","Cytoplasm","enzyme",0.001091852,0.00020487046,"up",1.4233469,1.4233469,0.5092873]
["Chondroitin Sulfate Biosynthesis",0.457,0.0517,"NaN","GXYLT1","glucoside xylosyltransferase 1","Cytoplasm","enzyme",0.0016147236,0.00061580446,"up",1.7539235,1.7539235,0.81058586]
["Hepatic Cholestasis",0.455,0.044,"NaN","CXCL8","C-X-C motif chemokine ligand 8","Extracellular Space","cytokine",0.0011259156,0.00022286079,"down",1.5851029,-1.5851029,-0.66457653]
["Hepatic Cholestasis",0.455,0.044,"NaN","IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["Hepatic Cholestasis",0.455,0.044,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Hepatic Cholestasis",0.455,0.044,"NaN","MYD88","myeloid differentiation primary response 88","Plasma Membrane","other",0.0019091989,0.0009046913,"down",1.3930262,-1.3930262,-0.47822243]
["Hepatic Cholestasis",0.455,0.044,"NaN","PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Hepatic Cholestasis",0.455,0.044,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Hepatic Cholestasis",0.455,0.044,"NaN","HNF4A","hepatocyte nuclear factor 4 alpha","Nucleus","transcription regulator",0.0018693322,0.0008653767,"up",1.4698008,1.4698008,0.5556207]
["Acyl-CoA Hydrolysis",0.448,0.0833,"NaN","HNF4A","hepatocyte nuclear factor 4 alpha","Nucleus","transcription regulator",0.0018693322,0.0008653767,"up",1.4698008,1.4698008,0.5556207]
["BER pathway",0.448,0.0833,"NaN","PCNA","proliferating cell nuclear antigen","Nucleus","enzyme",0.0032386743,0.0020517183,"down",1.3257968,-1.3257968,-0.40685973]
["Coagulation System",0.441,0.0571,"NaN","PLAUR","plasminogen activator, urokinase receptor","Plasma Membrane","transmembrane receptor",0.0010741793,0.00018365598,"down",1.485067,-1.485067,-0.57052803]
["Coagulation System",0.441,0.0571,"NaN","SERPINE1","serpin family E member 1","Extracellular Space","other",0.0016010772,0.00060374127,"up",1.3806411,1.3806411,0.46533832]
["GPCR-Mediated Nutrient Sensing in Enteroendocrine Cells",0.434,0.0471,"NaN","GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["GPCR-Mediated Nutrient Sensing in Enteroendocrine Cells",0.434,0.0471,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["GPCR-Mediated Nutrient Sensing in Enteroendocrine Cells",0.434,0.0471,"NaN","PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["GPCR-Mediated Nutrient Sensing in Enteroendocrine Cells",0.434,0.0471,"NaN","ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["Stearate Biosynthesis I (Animals)",0.426,0.0556,"NaN","HNF4A","hepatocyte nuclear factor 4 alpha","Nucleus","transcription regulator",0.0018693322,0.0008653767,"up",1.4698008,1.4698008,0.5556207]
["Stearate Biosynthesis I (Animals)",0.426,0.0556,"NaN","ELOVL6","ELOVL fatty acid elongase 6","Cytoplasm","enzyme",0.003911406,0.0026581388,"up",1.4015174,1.4015174,0.48698965]
["autophagy",0.426,0.0556,"NaN","STX17","syntaxin 17","Plasma Membrane","transporter",0.006206978,0.004881112,"up",1.4434947,1.4434947,0.52956575]
["autophagy",0.426,0.0556,"NaN","ATG10","autophagy related 10","Plasma Membrane","enzyme",0.0016202792,0.00063359755,"down",1.7660402,-1.7660402,-0.8205182]
["HIPPO signaling",0.424,0.0465,"NaN","DLG5","discs large homolog 5","Plasma Membrane","other",0.0049674492,0.003643224,"up",1.3818208,1.3818208,0.46657053]
["HIPPO signaling",0.424,0.0465,"NaN","SMAD5","SMAD family member 5","Nucleus","transcription regulator",0.0014749195,0.00048909907,"down",1.3112969,-1.3112969,-0.3909944]
["HIPPO signaling",0.424,0.0465,"NaN","PATJ","PATJ, crumbs cell polarity complex component","Plasma Membrane","other",0.012302879,0.010879122,"up",1.3560606,1.3560606,0.43942168]
["HIPPO signaling",0.424,0.0465,"NaN","SKP2","S-phase kinase-associated protein 2, E3 ubiquitin protein ligase","Nucleus","enzyme",0.0014867174,0.000499228,"up",1.348095,1.348095,0.4309222]
["Role of IL-17A in Psoriasis",0.42,0.0769,"NaN","CXCL8","C-X-C motif chemokine ligand 8","Extracellular Space","cytokine",0.0011259156,0.00022286079,"down",1.5851029,-1.5851029,-0.66457653]
["Glycogen Degradation III",0.42,0.0769,"NaN","PGM2","phosphoglucomutase 2","Cytoplasm","enzyme",0.0019427151,0.0009402669,"down",1.6117538,-1.6117538,-0.6886314]
["NAD Phosphorylation and Dephosphorylation",0.42,0.0769,"NaN","NNT","nicotinamide nucleotide transhydrogenase","Cytoplasm","enzyme",0.022877716,0.02156732,"down",1.3108017,-1.3108017,-0.3904495]
["Bile Acid Biosynthesis, Neutral Pathway",0.42,0.0769,"NaN","AKR1C4","aldo-keto reductase family 1, member C4","Cytoplasm","enzyme",0.0008743986,0.000103180544,"up",1.8595277,1.8595277,0.8949362]
["Bladder Cancer Signaling",0.415,0.046,"NaN","CXCL8","C-X-C motif chemokine ligand 8","Extracellular Space","cytokine",0.0011259156,0.00022286079,"down",1.5851029,-1.5851029,-0.66457653]
["Bladder Cancer Signaling",0.415,0.046,"NaN","CDH1","cadherin 1","Plasma Membrane","other",0.0017019173,0.0006999703,"up",1.452055,1.452055,0.5380961]
["Bladder Cancer Signaling",0.415,0.046,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Bladder Cancer Signaling",0.415,0.046,"NaN","CDKN1A","cyclin-dependent kinase inhibitor 1A","Nucleus","kinase",0.0012674241,0.00031876643,"down",1.4186804,-1.4186804,-0.5045496]
["Antigen Presentation Pathway",0.411,0.0541,"NaN","PSMB9","proteasome subunit beta 9","Cytoplasm","peptidase",0.0015865989,0.0005862627,"up",1.5161694,1.5161694,0.60043097]
["Antigen Presentation Pathway",0.411,0.0541,"NaN","HLA-F","major histocompatibility complex, class I, F","Plasma Membrane","transmembrane receptor",0.00070557836,5.4619704e-05,"up",1.622745,1.622745,0.6984363]
["Complement System",0.411,0.0541,"NaN","CD55","CD55 molecule (Cromer blood group)","Plasma Membrane","other",0.0022323814,0.0011921417,"down",1.4334465,-1.4334465,-0.5194881]
["Complement System",0.411,0.0541,"NaN","CD46","CD46 molecule","Plasma Membrane","other",0.0012233602,0.00028883747,"up",1.4813726,1.4813726,0.5669345]
["Notch Signaling",0.397,0.0526,"NaN","PSENEN","presenilin enhancer gamma secretase subunit","Plasma Membrane","peptidase",0.0017462111,0.00074735825,"up",1.374307,1.374307,0.45870435]
["Notch Signaling",0.397,0.0526,"NaN","APH1B","aph-1 homolog B, gamma secretase subunit","Other","peptidase",0.0012306612,0.00029680028,"up",1.5021218,1.5021218,0.5870018]
["Androgen Biosynthesis",0.395,0.0714,"NaN","AKR1C4","aldo-keto reductase family 1, member C4","Cytoplasm","enzyme",0.0008743986,0.000103180544,"up",1.8595277,1.8595277,0.8949362]
["Superpathway of Citrulline Metabolism",0.395,0.0714,"NaN","GLS","glutaminase","Cytoplasm","enzyme",0.0045107757,0.0032061748,"up",1.6075542,1.6075542,0.6848674]
["Phenylalanine Degradation IV (Mammalian, via Side Chain)",0.395,0.0714,"NaN","HPD","4-hydroxyphenylpyruvate dioxygenase","Cytoplasm","enzyme",0.0029613448,0.0018153565,"up",1.5377063,1.5377063,0.62077993]
["Colanic Acid Building Blocks Biosynthesis",0.395,0.0714,"NaN","MPI","mannose phosphate isomerase","Cytoplasm","enzyme",0.00091646257,0.00012077414,"up",1.4872181,1.4872181,0.5726163]
["Calcium-induced T Lymphocyte Apoptosis",0.389,0.0469,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Calcium-induced T Lymphocyte Apoptosis",0.389,0.0469,"NaN","MEF2D","myocyte enhancer factor 2D","Nucleus","transcription regulator",0.0006217929,3.203251e-05,"down",1.3555743,-1.3555743,-0.43890414]
["Calcium-induced T Lymphocyte Apoptosis",0.389,0.0469,"NaN","ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["Hypoxia Signaling in the Cardiovascular System",0.379,0.0462,"NaN","HSP90AA1","heat shock protein 90kDa alpha family class A member 1","Cytoplasm","enzyme",0.0005783946,2.0937947e-05,"up",1.5556576,1.5556576,0.63752455]
["Hypoxia Signaling in the Cardiovascular System",0.379,0.0462,"NaN","PTEN","phosphatase and tensin homolog","Cytoplasm","phosphatase",0.003135014,0.0019617465,"down",1.3675829,-1.3675829,-0.4516283]
["Hypoxia Signaling in the Cardiovascular System",0.379,0.0462,"NaN","ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["Vitamin-C Transport",0.373,0.0667,"NaN","SLC2A1","solute carrier family 2 member 1","Plasma Membrane","transporter",0.0010998568,0.00021028184,"down",1.3829497,-1.3829497,-0.4677487]
["Role of PKR in Interferon Induction and Antiviral Response",0.37,0.05,"NaN","IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["Role of PKR in Interferon Induction and Antiviral Response",0.37,0.05,"NaN","ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["Thyroid Cancer Signaling",0.37,0.05,"NaN","CDH1","cadherin 1","Plasma Membrane","other",0.0017019173,0.0006999703,"up",1.452055,1.452055,0.5380961]
["Thyroid Cancer Signaling",0.37,0.05,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Neuroprotective Role of THOP1 in Alzheimer's Disease",0.37,0.05,"NaN","PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Neuroprotective Role of THOP1 in Alzheimer's Disease",0.37,0.05,"NaN","HLA-F","major histocompatibility complex, class I, F","Plasma Membrane","transmembrane receptor",0.00070557836,5.4619704e-05,"up",1.622745,1.622745,0.6984363]
["Transcriptional Regulatory Network in Embryonic Stem Cells",0.37,0.05,"NaN","SOX2","SRY-box 2","Nucleus","transcription regulator",0.0013107243,0.00034832067,"up",1.4385506,1.4385506,0.52461594]
["Transcriptional Regulatory Network in Embryonic Stem Cells",0.37,0.05,"NaN","HNF4A","hepatocyte nuclear factor 4 alpha","Nucleus","transcription regulator",0.0018693322,0.0008653767,"up",1.4698008,1.4698008,0.5556207]
["Synaptic Long Term Potentiation",0.359,0.0417,1.342,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Synaptic Long Term Potentiation",0.359,0.0417,1.342,"MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Synaptic Long Term Potentiation",0.359,0.0417,1.342,"PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Synaptic Long Term Potentiation",0.359,0.0417,1.342,"ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["Synaptic Long Term Potentiation",0.359,0.0417,1.342,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["Heparan Sulfate Biosynthesis (Late Stages)",0.359,0.0448,"NaN","CHST2","carbohydrate sulfotransferase 2","Cytoplasm","enzyme",0.0010089864,0.0001642536,"down",1.9582679,-1.9582679,-0.96957815]
["Heparan Sulfate Biosynthesis (Late Stages)",0.359,0.0448,"NaN","CHST7","carbohydrate sulfotransferase 7","Cytoplasm","enzyme",0.001091852,0.00020487046,"up",1.4233469,1.4233469,0.5092873]
["Heparan Sulfate Biosynthesis (Late Stages)",0.359,0.0448,"NaN","GLCE","glucuronic acid epimerase","Cytoplasm","enzyme",0.0039742477,0.002717961,"down",1.3718114,-1.3718114,-0.45608214]
["GABA Receptor Signaling",0.359,0.0448,"NaN","GABRB3","gamma-aminobutyric acid type A receptor beta3 subunit","Plasma Membrane","ion channel",0.0012591777,0.00031486017,"up",2.7503364,2.7503364,1.4596081]
["GABA Receptor Signaling",0.359,0.0448,"NaN","GABARAP","GABA type A receptor-associated protein","Cytoplasm","transporter",0.00061091204,2.6046639e-05,"up",1.4928515,1.4928515,0.57807064]
["GABA Receptor Signaling",0.359,0.0448,"NaN","GPHN","gephyrin","Plasma Membrane","enzyme",0.0065242443,0.0051553696,"up",1.3237419,1.3237419,0.40462187]
["γ-glutamyl Cycle",0.352,0.0625,"NaN","GCLC","glutamate-cysteine ligase catalytic subunit","Cytoplasm","enzyme",0.001961328,0.0009667417,"down",1.3574277,-1.3574277,-0.44087538]
["Parkinson's Signaling",0.352,0.0625,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Gustation Pathway",0.346,0.041,"NaN","PDE3B","phosphodiesterase 3B","Cytoplasm","enzyme",0.0026252405,0.0015308249,"up",1.3255126,1.3255126,0.40655044]
["Gustation Pathway",0.346,0.041,"NaN","ASIC1","acid sensing ion channel subunit 1","Plasma Membrane","ion channel",0.005377771,0.0040252223,"up",1.512104,1.512104,0.5965574]
["Gustation Pathway",0.346,0.041,"NaN","PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Gustation Pathway",0.346,0.041,"NaN","ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["Gustation Pathway",0.346,0.041,"NaN","PANX1","pannexin 1","Plasma Membrane","transporter",0.0016202792,0.00063036644,"up",1.3148646,1.3148646,0.39491427]
["Role of RIG1-like Receptors in Antiviral Innate Immunity",0.334,0.0465,"NaN","IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["Role of RIG1-like Receptors in Antiviral Innate Immunity",0.334,0.0465,"NaN","TBK1","TANK binding kinase 1","Cytoplasm","kinase",0.005976595,0.004633019,"down",1.3411525,-1.3411525,-0.42347333]
["Mitochondrial L-carnitine Shuttle Pathway",0.333,0.0588,"NaN","CPT1C","carnitine palmitoyltransferase 1C","Cytoplasm","enzyme",0.004112417,0.0028478752,"up",1.3991864,1.3991864,0.48458815]
["Triacylglycerol Degradation",0.323,0.0455,"NaN","LPL","lipoprotein lipase","Cytoplasm","enzyme",0.0019518846,0.00095576775,"down",1.3136675,-1.3136675,-0.3936002]
["Triacylglycerol Degradation",0.323,0.0455,"NaN","ABHD2","abhydrolase domain containing 2","Other","enzyme",0.0048918244,0.0035666921,"up",1.3477682,1.3477682,0.43057236]
["Melatonin Signaling",0.323,0.0423,"NaN","PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Melatonin Signaling",0.323,0.0423,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Melatonin Signaling",0.323,0.0423,"NaN","PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["FXR/RXR Activation",0.319,0.0397,"NaN","SDC1","syndecan 1","Plasma Membrane","enzyme",0.001123322,0.00022071275,"up",1.3963997,1.3963997,0.48171198]
["FXR/RXR Activation",0.319,0.0397,"NaN","LPL","lipoprotein lipase","Cytoplasm","enzyme",0.0019518846,0.00095576775,"down",1.3136675,-1.3136675,-0.3936002]
["FXR/RXR Activation",0.319,0.0397,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["FXR/RXR Activation",0.319,0.0397,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["FXR/RXR Activation",0.319,0.0397,"NaN","HNF4A","hepatocyte nuclear factor 4 alpha","Nucleus","transcription regulator",0.0018693322,0.0008653767,"up",1.4698008,1.4698008,0.5556207]
["CDK5 Signaling",0.317,0.0404,"NaN","ITGB1","integrin subunit beta 1","Plasma Membrane","transmembrane receptor",0.0010771177,0.00018568568,"down",1.7316988,-1.7316988,-0.792188]
["CDK5 Signaling",0.317,0.0404,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["CDK5 Signaling",0.317,0.0404,"NaN","PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["CDK5 Signaling",0.317,0.0404,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["Atherosclerosis Signaling",0.313,0.0394,"NaN","CXCL8","C-X-C motif chemokine ligand 8","Extracellular Space","cytokine",0.0011259156,0.00022286079,"down",1.5851029,-1.5851029,-0.66457653]
["Atherosclerosis Signaling",0.313,0.0394,"NaN","CXCR4","C-X-C motif chemokine receptor 4","Plasma Membrane","G-protein coupled receptor",0.0018305046,0.00083504117,"down",1.3248457,-1.3248457,-0.4058243]
["Atherosclerosis Signaling",0.313,0.0394,"NaN","LPL","lipoprotein lipase","Cytoplasm","enzyme",0.0019518846,0.00095576775,"down",1.3136675,-1.3136675,-0.3936002]
["Atherosclerosis Signaling",0.313,0.0394,"NaN","TNFRSF12A","tumor necrosis factor receptor superfamily member 12A","Plasma Membrane","transmembrane receptor",0.0014867174,0.00050635205,"up",1.3754094,1.3754094,0.45986107]
["Atherosclerosis Signaling",0.313,0.0394,"NaN","PAFAH1B3","platelet activating factor acetylhydrolase 1b catalytic subunit 3","Cytoplasm","enzyme",0.0029175605,0.0017729017,"up",1.3077043,1.3077043,0.38703638]
["Toll-like Receptor Signaling",0.299,0.0405,"NaN","IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["Toll-like Receptor Signaling",0.299,0.0405,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Toll-like Receptor Signaling",0.299,0.0405,"NaN","MYD88","myeloid differentiation primary response 88","Plasma Membrane","other",0.0019091989,0.0009046913,"down",1.3930262,-1.3930262,-0.47822243]
["Glutathione Redox Reactions I",0.299,0.0526,"NaN","GSTT2/GSTT2B","glutathione S-transferase theta 2 (gene/pseudogene)","Cytoplasm","enzyme",0.0011259156,0.00022387244,"up",1.4915317,1.4915317,0.5767947]
["G-Protein Coupled Receptor Signaling",0.29,0.037,"NaN","PIK3R3","phosphoinositide-3-kinase regulatory subunit 3","Cytoplasm","kinase",0.0011846017,0.00025720376,"down",1.4334757,-1.4334757,-0.5195175]
["G-Protein Coupled Receptor Signaling",0.29,0.037,"NaN","IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["G-Protein Coupled Receptor Signaling",0.29,0.037,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["G-Protein Coupled Receptor Signaling",0.29,0.037,"NaN","GRB2","growth factor receptor bound protein 2","Cytoplasm","kinase",0.0036755858,0.0024531144,"down",1.3941183,-1.3941183,-0.47935298]
["G-Protein Coupled Receptor Signaling",0.29,0.037,"NaN","PDE3B","phosphodiesterase 3B","Cytoplasm","enzyme",0.0026252405,0.0015308249,"up",1.3255126,1.3255126,0.40655044]
["G-Protein Coupled Receptor Signaling",0.29,0.037,"NaN","FGFR1","fibroblast growth factor receptor 1","Plasma Membrane","kinase",0.005185627,0.0038445531,"up",1.4777534,1.4777534,0.5634055]
["G-Protein Coupled Receptor Signaling",0.29,0.037,"NaN","PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["G-Protein Coupled Receptor Signaling",0.29,0.037,"NaN","AKT3","v-akt murine thymoma viral oncogene homolog 3","Cytoplasm","kinase",0.009432929,0.007966396,"up",1.405944,1.405944,0.49153912]
["G-Protein Coupled Receptor Signaling",0.29,0.037,"NaN","FGFR2","fibroblast growth factor receptor 2","Plasma Membrane","kinase",0.0010386986,0.00017440978,"up",1.7208374,1.7208374,0.78311074]
["G-Protein Coupled Receptor Signaling",0.29,0.037,"NaN","ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["Role of Wnt/GSK-3β Signaling in the Pathogenesis of Influenza",0.283,0.0395,"NaN","FZD10","frizzled class receptor 10","Plasma Membrane","G-protein coupled receptor",0.00084399927,9.184798e-05,"down",1.4670624,-1.4670624,-0.5529302]
["Role of Wnt/GSK-3β Signaling in the Pathogenesis of Influenza",0.283,0.0395,"NaN","FZD5","frizzled class receptor 5","Plasma Membrane","G-protein coupled receptor",0.0011555209,0.00024123449,"down",1.5153433,-1.5153433,-0.59964466]
["Role of Wnt/GSK-3β Signaling in the Pathogenesis of Influenza",0.283,0.0395,"NaN","FZD1","frizzled class receptor 1","Plasma Membrane","G-protein coupled receptor",0.0036817046,0.002460812,"down",1.529664,-1.529664,-0.6132148]
["Cardiomyocyte Differentiation via BMP Receptors",0.283,0.05,"NaN","ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["DNA Methylation and Transcriptional Repression Signaling",0.283,0.05,"NaN","SAP18","Sin3A associated protein 18kDa","Nucleus","transcription regulator",0.0006217929,3.2134e-05,"down",1.6716334,-1.6716334,-0.74125844]
["1D-myo-inositol Hexakisphosphate Biosynthesis II (Mammalian)",0.283,0.05,"NaN","INPP5A","inositol polyphosphate-5-phosphatase A","Plasma Membrane","phosphatase",0.0017193076,0.00071636395,"up",1.6724749,1.6724749,0.7419845]
["Chondroitin Sulfate Biosynthesis (Late Stages)",0.274,0.0408,"NaN","CHST2","carbohydrate sulfotransferase 2","Cytoplasm","enzyme",0.0010089864,0.0001642536,"down",1.9582679,-1.9582679,-0.96957815]
["Chondroitin Sulfate Biosynthesis (Late Stages)",0.274,0.0408,"NaN","CHST7","carbohydrate sulfotransferase 7","Cytoplasm","enzyme",0.001091852,0.00020487046,"up",1.4233469,1.4233469,0.5092873]
["Dopamine-DARPP32 Feedback in cAMP Signaling",0.273,0.037,0,"KCNJ12","potassium voltage-gated channel subfamily J member 12","Plasma Membrane","ion channel",0.0022579338,0.0012125941,"up",1.3948784,1.3948784,0.48013934]
["Dopamine-DARPP32 Feedback in cAMP Signaling",0.273,0.037,0,"PRKCI","protein kinase C iota","Cytoplasm","kinase",0.002677772,0.0015752957,"down",1.4061365,-1.4061365,-0.49173665]
["Dopamine-DARPP32 Feedback in cAMP Signaling",0.273,0.037,0,"ATF1","activating transcription factor 1","Nucleus","transcription regulator",0.0070709703,0.005685401,"down",1.3784643,-1.3784643,-0.46306193]
["Dopamine-DARPP32 Feedback in cAMP Signaling",0.273,0.037,0,"PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Dopamine-DARPP32 Feedback in cAMP Signaling",0.273,0.037,0,"ITPR1","inositol 1,4,5-trisphosphate receptor type 1","Cytoplasm","ion channel",0.0039895363,0.0027335712,"up",1.5355254,1.5355254,0.6187324]
["Dopamine-DARPP32 Feedback in cAMP Signaling",0.273,0.037,0,"ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["Maturity Onset Diabetes of Young (MODY) Signaling",0.269,0.0476,"NaN","HNF4A","hepatocyte nuclear factor 4 alpha","Nucleus","transcription regulator",0.0018693322,0.0008653767,"up",1.4698008,1.4698008,0.5556207]
["Endoplasmic Reticulum Stress Pathway",0.269,0.0476,"NaN","HSPA5","heat shock protein family A (Hsp70) member 5","Cytoplasm","enzyme",0.007907775,0.006494456,"down",1.3693051,-1.3693051,-0.45344397]
["Fatty Acid α-oxidation",0.256,0.0455,"NaN","PTGS2","prostaglandin-endoperoxide synthase 2","Cytoplasm","enzyme",0.0012584343,0.00031259237,"down",1.4767396,-1.4767396,-0.5624155]
["Gαs Signaling",0.254,0.0367,"NaN","GNG4","G protein subunit gamma 4","Plasma Membrane","enzyme",0.0017953549,0.00079175,"up",1.3405488,1.3405488,0.4228237]
["Gαs Signaling",0.254,0.0367,"NaN","MAPK1","mitogen-activated protein kinase 1","Cytoplasm","kinase",0.00067191356,4.1198415e-05,"up",1.3719624,1.3719624,0.45624098]
["Gαs Signaling",0.254,0.0367,"NaN","PRKAG2","protein kinase AMP-activated non-catalytic subunit gamma 2","Cytoplasm","kinase",0.0019103753,0.00090664666,"up",1.322077,1.322077,0.40280625]
["Gαs Signaling",0.254,0.0367,"NaN","ATF2","activating transcription factor 2","Nucleus","transcription regulator",0.0054514054,0.0041014664,"up",1.4380094,1.4380094,0.52407306]
["CD27 Signaling in Lymphocytes",0.248,0.0385,"NaN","IKBKG","inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma","Nucleus","kinase",0.004360689,0.003061121,"up",1.3711545,1.3711545,0.4553912]
["CD27 Signaling in Lymphocytes",0.248,0.0385,"NaN","MAPK9","mitogen-activated protein kinase 9","Cytoplasm","kinase",0.0006672249,3.830129e-05,"up",2.1703203,2.1703203,1.1179079]
["TCA Cycle II (Eukaryotic)",0.243,0.0435,"NaN","DHTKD1","dehydrogenase E1 and transketolase domain containing 1","Cytoplasm","enzyme",0.0012233602,0.0002803407,"up",1.3357142,1.3357142,0.41761136]
["Unfolded protein response",0.233,0.037,"NaN","CEBPB","CCAAT/enhancer binding protein beta","Nucleus","transcription regulator",0.021593252,0.020254135,"down",1.3026826,-1.3026826,-0.38148564]
["Unfolded protein response",0.233,0.037,"NaN","HSPA5","heat shock protein family A (Hsp70) member 5","Cytoplasm","enzyme",0.007907775,0.006494456,"down",1.3693051,-1.3693051,-0.45344397]
["CDP-diacylglycerol Biosynthesis I",0.232,0.0417,"NaN","MBOAT2","membrane bound O-acyltransferase domain containing 2","Cytoplasm","enzyme",0.001550606,0.00055170426,"up",1.5328599,1.5328599,0.61622584]
["Lipid Antigen Presentation by CD1",0.211,0.0385,"NaN","PSAP","prosaposin","Extracellular Space","other",0.00086182606,9.835655e-05,"down",1.5208821,-1.5208821,-0.60490835]
["NAD Salvage Pathway II",0.211,0.0385,"NaN","NUDT12","nudix hydrolase 12","Cytoplasm","phosphatase",0.0015242294,0.00053365715,"up",1.4112375,1.4112375,0.49696076]
["Phosphatidylglycerol Biosynthesis II (Non-plastidic)",0.211,0.0385,"NaN","MBOAT2","membrane bound O-acyltransferase domain containing 2","Cytoplasm","enzyme",0.001550606,0.00055170426,"up",1.5328599,1.5328599,0.61622584]